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An option to calculate the GC content even if there are gaps, 'N's, or other ambiguous bases (ie. not ACGTSW) in the region probably ought to be the default. Maybe as the proportion of ACGTSW bases.
An option to calculate the GC content even if there are gaps, 'N's, or other ambiguous bases (ie. not ACGTSW) in the region probably ought to be the default. Maybe as the proportion of ACGTSW bases.