diff --git a/Formula/n/nanobind.rb b/Formula/n/nanobind.rb
new file mode 100644
index 000000000000..1d669e3f22fc
--- /dev/null
+++ b/Formula/n/nanobind.rb
@@ -0,0 +1,94 @@
+class Nanobind < Formula
+  desc "Tiny and efficient C++/Python bindings"
+  homepage "https://github.com/wjakob/nanobind"
+  url "https://github.com/wjakob/nanobind/archive/refs/tags/v2.1.0.tar.gz"
+  sha256 "c37c53c60ada5fe1c956e24bd4b83af669a2309bf952bd251f36a7d2fa3bacf0"
+  license "BSD-3-Clause"
+  head "https://github.com/wjakob/nanobind.git", branch: "master"
+
+  bottle do
+    sha256 cellar: :any_skip_relocation, all: "67d3bc9718d09845035fdb44fa3ac8e60e80bcc8170900f25a945589eeb02e9d"
+  end
+
+  depends_on "cmake" => [:build, :test]
+  depends_on "python@3.12" => [:build, :test]
+  depends_on "robin-map" => [:build, :test]
+
+  def install
+    system "cmake", "-S", ".", "-B", "build",
+                    "-DNB_USE_SUBMODULE_DEPS=OFF",
+                    "-DNB_CREATE_INSTALL_RULES=ON",
+                    "-DNB_INSTALL_DATADIR=#{pkgshare}",
+                    *std_cmake_args
+    system "cmake", "--build", "build"
+    system "cmake", "--install", "build"
+
+    python_versions = Formula.names
+                             .select { |name| name.start_with? "python@" }
+                             .map { |py| Version.new(py.delete_prefix("python@")) }
+    python_versions.each do |pyver|
+      site_packages = lib/"python#{pyver}/site-packages"
+      site_packages.install_symlink pkgshare
+    end
+  end
+
+  test do
+    python = "python3.12"
+
+    (testpath/"my_ext.cpp").write <<~CPP
+      #include <nanobind/nanobind.h>
+
+      int add(int a, int b) { return a + b; }
+
+      NB_MODULE(my_ext, m) {
+          m.def("add", &add);
+      }
+    CPP
+
+    python_version = Language::Python.major_minor_version(python)
+
+    cmakelists = testpath/"CMakeLists.txt"
+    cmakelists.write <<~CMAKE
+      cmake_minimum_required(VERSION 3.27)
+      project(test_nanobind)
+
+      find_package(Python #{python_version} COMPONENTS Interpreter Development.Module REQUIRED)
+      find_package(nanobind CONFIG REQUIRED)
+      nanobind_add_module(my_ext my_ext.cpp)
+    CMAKE
+
+    system "cmake", "-S", ".", "-B", "build", *std_cmake_args
+    system "cmake", "--build", "build"
+
+    cd "build" do
+      assert_equal "3", shell_output("#{python} -c 'import my_ext; print(my_ext.add(1, 2))'").chomp
+    end
+
+    ENV.delete("CMAKE_PREFIX_PATH")
+    cmakelists.unlink
+    cmakelists.write <<~CMAKE
+      cmake_minimum_required(VERSION 3.27)
+      project(test_nanobind)
+
+      # Ensure that nanobind can be found only via `execute_process` below.
+      set(CMAKE_FIND_USE_SYSTEM_ENVIRONMENT_PATH FALSE)
+      set(CMAKE_FIND_USE_CMAKE_SYSTEM_PATH FALSE)
+      find_package(Python #{python_version} COMPONENTS Interpreter Development.Module REQUIRED)
+      execute_process(
+        COMMAND "${Python_EXECUTABLE}" -m nanobind --cmake_dir
+        OUTPUT_STRIP_TRAILING_WHITESPACE OUTPUT_VARIABLE nanobind_ROOT COMMAND_ERROR_IS_FATAL ANY)
+      find_package(nanobind CONFIG REQUIRED)
+      nanobind_add_module(my_ext my_ext.cpp)
+    CMAKE
+
+    prefix_path_dirs = deps.filter_map { |dep| dep.to_formula.opt_prefix if !dep.build? || dep.test? }
+    system "cmake", "-S", ".", "-B", "build-python",
+                    "-DCMAKE_PREFIX_PATH=#{prefix_path_dirs.join(";")}",
+                    *std_cmake_args
+    system "cmake", "--build", "build-python"
+
+    cd "build-python" do
+      assert_equal "3", shell_output("#{python} -c 'import my_ext; print(my_ext.add(1, 2))'").chomp
+    end
+  end
+end