diff --git a/readme.txt b/readme.md similarity index 63% rename from readme.txt rename to readme.md index ef90b8b..a915b43 100644 --- a/readme.txt +++ b/readme.md @@ -1,33 +1,37 @@ NEURON mod files for the Na, K-A, and K-DR currents from the paper: -Safronov and Vogel, J.Physiol. 487:91-106 (1995). +Safronov and Vogel, *J.Physiol*. 487:91-106 (1995). -Running the kinetics_na.hoc or kinetics_k.hoc simulation files +- Running the kinetics_na.hoc or kinetics_k.hoc simulation files will show the activation and inactivation steady-states, the time constants, and a family of curves generated modeling the same protocols used in the paper. -Markers show the experimental values estimated from Figs.4C +- Markers show the experimental values estimated from Figs.4C (Na), 8C (KA), and 10C (KDR) of the paper. Note that m is used rather than the more usual m^3 for activation of the Na current. Na recovery from inactivation is not implemented. -Under unix systems: +## Under unix systems: to compile the mod files use the command -nrnivmodl +``` nrnivmodl ``` and run the simulation hoc file with the command -nrngui kinetics_na.hoc +``` nrngui kinetics_na.hoc ``` or -nrngui kinetics_k.hoc +``` nrngui kinetics_k.hoc ``` - -Under Windows using NEURON 5.1: -to compile the mod files use the "mknrndll" command. +## Under Windows using NEURON 5.1: +to compile the mod files use the ``` mknrndll ``` command. A double click on the simulation files kinetics_na.hoc or kinetics_k.hoc will open the simulation windows. +\ Questions on the model parameters should be directed to the authors. Questions on how to use this model with NEURON should be directed to michele@pa.ibf.cnr.it + +Changelog: +---------- +2024-10: Converted readme to markdown