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For low base quality of sequences #202

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YouxinZhao opened this issue Mar 26, 2024 · 1 comment
Open

For low base quality of sequences #202

YouxinZhao opened this issue Mar 26, 2024 · 1 comment

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@YouxinZhao
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I am using nextDenovo to assamble genome with ONT reads.
The long reads usually have low base quality.
And I wonder how these sequences will be handled in Nextdenove? Discard or correct?
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@moold
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moold commented Mar 26, 2024

Nextdenovo discards reads with low mapping coverage or clips regions of low mapping coverage in reads, and low-quality reads generally have lower mapping coverage.

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