The crispr subcommand currently loops per-pattern via search_with_fn (bin/crispr.rs L227), but could use search_encoded_patterns (the v2 path used in run_batch_v2 in grep.rs) to batch all guides into a single SIMD pass per text chunk, which would dramatically improve throughput for multi-guide CRISPR off-target screening workloads.
The
crisprsubcommand currently loops per-pattern viasearch_with_fn(bin/crispr.rs L227), but could usesearch_encoded_patterns(the v2 path used inrun_batch_v2in grep.rs) to batch all guides into a single SIMD pass per text chunk, which would dramatically improve throughput for multi-guide CRISPR off-target screening workloads.