diff --git a/.gitignore b/.gitignore
index d08bdd88..1c30809a 100644
--- a/.gitignore
+++ b/.gitignore
@@ -15,4 +15,5 @@ benchmark/bin/env.sh
 benchmark/src/results
 benchmark/src/results/overlap
 mprofile*dat
-*csv
\ No newline at end of file
+*csv
+!docs/notebooks/example.csv
\ No newline at end of file
diff --git a/Cargo.lock b/Cargo.lock
index d84574f0..946f46a3 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -6346,9 +6346,9 @@ dependencies = [
 
 [[package]]
 name = "serde_json"
-version = "1.0.138"
+version = "1.0.140"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "d434192e7da787e94a6ea7e9670b26a036d0ca41e0b7efb2676dd32bae872949"
+checksum = "20068b6e96dc6c9bd23e01df8827e6c7e1f2fddd43c21810382803c136b99373"
 dependencies = [
  "indexmap",
  "itoa",
diff --git a/docs/notebooks/base_sequence_quality.ipynb b/docs/notebooks/base_sequence_quality.ipynb
new file mode 100644
index 00000000..1e484745
--- /dev/null
+++ b/docs/notebooks/base_sequence_quality.ipynb
@@ -0,0 +1,514 @@
+{
+ "cells": [
+  {
+   "cell_type": "markdown",
+   "id": "76af9b7e",
+   "metadata": {},
+   "source": [
+    "# Team Z6\n",
+    "- Mariusz Paluch\n",
+    "- Bartłomiej Ściseł\n",
+    "- Jakub Winter"
+   ]
+  },
+  {
+   "cell_type": "markdown",
+   "id": "83d7ccd7",
+   "metadata": {},
+   "source": [
+    "### Import dependencies"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 14,
+   "id": "58b40aa6",
+   "metadata": {},
+   "outputs": [],
+   "source": [
+    "import pandas as pd\n",
+    "\n",
+    "import polars_bio as pb"
+   ]
+  },
+  {
+   "cell_type": "markdown",
+   "id": "2e29cd0a",
+   "metadata": {},
+   "source": [
+    "### Usage examples"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 15,
+   "id": "b0d81403",
+   "metadata": {},
+   "outputs": [],
+   "source": [
+    "pb.set_option(\"datafusion.execution.target_partitions\", \"2\")"
+   ]
+  },
+  {
+   "cell_type": "markdown",
+   "id": "b238193d",
+   "metadata": {},
+   "source": [
+    "#### Usage example - .fastq file"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 16,
+   "id": "0420c240",
+   "metadata": {},
+   "outputs": [
+    {
+     "name": "stdout",
+     "output_type": "stream",
+     "text": [
+      "    pos     avg    q1  median    q3  lower  upper\n",
+      "46    0  30.135  31.0    33.0  34.0   26.5   38.5\n",
+      "14    1  31.210  31.0    34.0  34.0   26.5   38.5\n",
+      "54    2  32.015  31.0    34.0  34.0   26.5   38.5\n",
+      "99    3  35.690  35.0    37.0  37.0   32.0   40.0\n",
+      "7     4  35.680  35.0    37.0  37.0   32.0   40.0\n",
+      "..  ...     ...   ...     ...   ...    ...    ...\n",
+      "95   96  31.315  32.0    34.0  35.0   27.5   39.5\n",
+      "62   97  30.670  31.0    34.0  35.0   25.0   41.0\n",
+      "67   98  31.550  32.0    34.0  35.0   27.5   39.5\n",
+      "53   99  31.250  32.0    34.0  35.0   27.5   39.5\n",
+      "55  100  31.105  31.0    34.0  35.0   25.0   41.0\n",
+      "\n",
+      "[101 rows x 7 columns]\n"
+     ]
+    }
+   ],
+   "source": [
+    "result = pb.base_sequence_quality(\"example.fastq\", output_type=\"pandas.DataFrame\").sort_values(by=\"pos\")\n",
+    "print(result)"
+   ]
+  },
+  {
+   "cell_type": "markdown",
+   "id": "d8eb42e4",
+   "metadata": {},
+   "source": [
+    "##### Results visualization\n"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 17,
+   "id": "7322aae3",
+   "metadata": {},
+   "outputs": [
+    {
+     "data": {
+      "image/png": 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",
+      "text/plain": [
+       "<Figure size 1500x500 with 1 Axes>"
+      ]
+     },
+     "metadata": {},
+     "output_type": "display_data"
+    }
+   ],
+   "source": [
+    "pb.visualize_base_sequence_quality(result)"
+   ]
+  },
+  {
+   "cell_type": "markdown",
+   "id": "5126c39b",
+   "metadata": {},
+   "source": [
+    "##### Performance Benchmarking\n",
+    "| Implementation | Target Partitions | Time  |\n",
+    "| -------------- | ----------------- | ----- |\n",
+    "| fastqc-rs      | -                 | 22.9s |\n",
+    "| polars_bio     | 1                 | 9.0s  |\n",
+    "| polars_bio     | 2                 | 7.8s  |\n",
+    "| polars_bio     | 4                 | 14.9s |\n",
+    "| polars_bio     | 8                 | 7.4s  |\n",
+    "\n",
+    "- The measured execution time is for the algorithm to run on file ftp://ftp.sra.ebi.ac.uk/vol1/fastq/ERR194/ERR194147/ERR194147.fastq.gz, which contains about 8,240,000 records.\n",
+    "- The `fastqc-rs` execution time applies only to the base sequence quality task (pieces of code relating to other tasks have been removed for the purpose of this comparison).\n"
+   ]
+  },
+  {
+   "cell_type": "markdown",
+   "id": "9886c394",
+   "metadata": {},
+   "source": [
+    "#### Usage example - .csv file"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 18,
+   "id": "66c3af24",
+   "metadata": {},
+   "outputs": [
+    {
+     "data": {
+      "text/html": [
+       "<div><style>\n",
+       ".dataframe > thead > tr,\n",
+       ".dataframe > tbody > tr {\n",
+       "  text-align: right;\n",
+       "  white-space: pre-wrap;\n",
+       "}\n",
+       "</style>\n",
+       "<small>shape: (101, 7)</small><table border=\"1\" class=\"dataframe\"><thead><tr><th>pos</th><th>avg</th><th>q1</th><th>median</th><th>q3</th><th>lower</th><th>upper</th></tr><tr><td>u64</td><td>f64</td><td>f64</td><td>f64</td><td>f64</td><td>f64</td><td>f64</td></tr></thead><tbody><tr><td>0</td><td>30.135</td><td>31.0</td><td>33.0</td><td>34.0</td><td>26.5</td><td>38.5</td></tr><tr><td>1</td><td>31.21</td><td>31.0</td><td>34.0</td><td>34.0</td><td>26.5</td><td>38.5</td></tr><tr><td>2</td><td>32.015</td><td>31.0</td><td>34.0</td><td>34.0</td><td>26.5</td><td>38.5</td></tr><tr><td>3</td><td>35.69</td><td>35.0</td><td>37.0</td><td>37.0</td><td>32.0</td><td>40.0</td></tr><tr><td>4</td><td>35.68</td><td>35.0</td><td>37.0</td><td>37.0</td><td>32.0</td><td>40.0</td></tr><tr><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td></tr><tr><td>96</td><td>31.315</td><td>32.0</td><td>34.0</td><td>35.0</td><td>27.5</td><td>39.5</td></tr><tr><td>97</td><td>30.67</td><td>31.0</td><td>34.0</td><td>35.0</td><td>25.0</td><td>41.0</td></tr><tr><td>98</td><td>31.55</td><td>32.0</td><td>34.0</td><td>35.0</td><td>27.5</td><td>39.5</td></tr><tr><td>99</td><td>31.25</td><td>32.0</td><td>34.0</td><td>35.0</td><td>27.5</td><td>39.5</td></tr><tr><td>100</td><td>31.105</td><td>31.0</td><td>34.0</td><td>35.0</td><td>25.0</td><td>41.0</td></tr></tbody></table></div>"
+      ],
+      "text/plain": [
+       "shape: (101, 7)\n",
+       "┌─────┬────────┬──────┬────────┬──────┬───────┬───────┐\n",
+       "│ pos ┆ avg    ┆ q1   ┆ median ┆ q3   ┆ lower ┆ upper │\n",
+       "│ --- ┆ ---    ┆ ---  ┆ ---    ┆ ---  ┆ ---   ┆ ---   │\n",
+       "│ u64 ┆ f64    ┆ f64  ┆ f64    ┆ f64  ┆ f64   ┆ f64   │\n",
+       "╞═════╪════════╪══════╪════════╪══════╪═══════╪═══════╡\n",
+       "│ 0   ┆ 30.135 ┆ 31.0 ┆ 33.0   ┆ 34.0 ┆ 26.5  ┆ 38.5  │\n",
+       "│ 1   ┆ 31.21  ┆ 31.0 ┆ 34.0   ┆ 34.0 ┆ 26.5  ┆ 38.5  │\n",
+       "│ 2   ┆ 32.015 ┆ 31.0 ┆ 34.0   ┆ 34.0 ┆ 26.5  ┆ 38.5  │\n",
+       "│ 3   ┆ 35.69  ┆ 35.0 ┆ 37.0   ┆ 37.0 ┆ 32.0  ┆ 40.0  │\n",
+       "│ 4   ┆ 35.68  ┆ 35.0 ┆ 37.0   ┆ 37.0 ┆ 32.0  ┆ 40.0  │\n",
+       "│ …   ┆ …      ┆ …    ┆ …      ┆ …    ┆ …     ┆ …     │\n",
+       "│ 96  ┆ 31.315 ┆ 32.0 ┆ 34.0   ┆ 35.0 ┆ 27.5  ┆ 39.5  │\n",
+       "│ 97  ┆ 30.67  ┆ 31.0 ┆ 34.0   ┆ 35.0 ┆ 25.0  ┆ 41.0  │\n",
+       "│ 98  ┆ 31.55  ┆ 32.0 ┆ 34.0   ┆ 35.0 ┆ 27.5  ┆ 39.5  │\n",
+       "│ 99  ┆ 31.25  ┆ 32.0 ┆ 34.0   ┆ 35.0 ┆ 27.5  ┆ 39.5  │\n",
+       "│ 100 ┆ 31.105 ┆ 31.0 ┆ 34.0   ┆ 35.0 ┆ 25.0  ┆ 41.0  │\n",
+       "└─────┴────────┴──────┴────────┴──────┴───────┴───────┘"
+      ]
+     },
+     "execution_count": 18,
+     "metadata": {},
+     "output_type": "execute_result"
+    }
+   ],
+   "source": [
+    "pb.base_sequence_quality(\"example.csv\").sort(by=\"pos\")"
+   ]
+  },
+  {
+   "cell_type": "markdown",
+   "id": "5ab1da41",
+   "metadata": {},
+   "source": [
+    "#### Usage example - .parquet file"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 19,
+   "id": "a2cb9c97",
+   "metadata": {},
+   "outputs": [
+    {
+     "data": {
+      "text/html": [
+       "<div><style>\n",
+       ".dataframe > thead > tr,\n",
+       ".dataframe > tbody > tr {\n",
+       "  text-align: right;\n",
+       "  white-space: pre-wrap;\n",
+       "}\n",
+       "</style>\n",
+       "<small>shape: (101, 7)</small><table border=\"1\" class=\"dataframe\"><thead><tr><th>pos</th><th>avg</th><th>q1</th><th>median</th><th>q3</th><th>lower</th><th>upper</th></tr><tr><td>u64</td><td>f64</td><td>f64</td><td>f64</td><td>f64</td><td>f64</td><td>f64</td></tr></thead><tbody><tr><td>0</td><td>30.135</td><td>31.0</td><td>33.0</td><td>34.0</td><td>26.5</td><td>38.5</td></tr><tr><td>1</td><td>31.21</td><td>31.0</td><td>34.0</td><td>34.0</td><td>26.5</td><td>38.5</td></tr><tr><td>2</td><td>32.015</td><td>31.0</td><td>34.0</td><td>34.0</td><td>26.5</td><td>38.5</td></tr><tr><td>3</td><td>35.69</td><td>35.0</td><td>37.0</td><td>37.0</td><td>32.0</td><td>40.0</td></tr><tr><td>4</td><td>35.68</td><td>35.0</td><td>37.0</td><td>37.0</td><td>32.0</td><td>40.0</td></tr><tr><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td></tr><tr><td>96</td><td>31.315</td><td>32.0</td><td>34.0</td><td>35.0</td><td>27.5</td><td>39.5</td></tr><tr><td>97</td><td>30.67</td><td>31.0</td><td>34.0</td><td>35.0</td><td>25.0</td><td>41.0</td></tr><tr><td>98</td><td>31.55</td><td>32.0</td><td>34.0</td><td>35.0</td><td>27.5</td><td>39.5</td></tr><tr><td>99</td><td>31.25</td><td>32.0</td><td>34.0</td><td>35.0</td><td>27.5</td><td>39.5</td></tr><tr><td>100</td><td>31.105</td><td>31.0</td><td>34.0</td><td>35.0</td><td>25.0</td><td>41.0</td></tr></tbody></table></div>"
+      ],
+      "text/plain": [
+       "shape: (101, 7)\n",
+       "┌─────┬────────┬──────┬────────┬──────┬───────┬───────┐\n",
+       "│ pos ┆ avg    ┆ q1   ┆ median ┆ q3   ┆ lower ┆ upper │\n",
+       "│ --- ┆ ---    ┆ ---  ┆ ---    ┆ ---  ┆ ---   ┆ ---   │\n",
+       "│ u64 ┆ f64    ┆ f64  ┆ f64    ┆ f64  ┆ f64   ┆ f64   │\n",
+       "╞═════╪════════╪══════╪════════╪══════╪═══════╪═══════╡\n",
+       "│ 0   ┆ 30.135 ┆ 31.0 ┆ 33.0   ┆ 34.0 ┆ 26.5  ┆ 38.5  │\n",
+       "│ 1   ┆ 31.21  ┆ 31.0 ┆ 34.0   ┆ 34.0 ┆ 26.5  ┆ 38.5  │\n",
+       "│ 2   ┆ 32.015 ┆ 31.0 ┆ 34.0   ┆ 34.0 ┆ 26.5  ┆ 38.5  │\n",
+       "│ 3   ┆ 35.69  ┆ 35.0 ┆ 37.0   ┆ 37.0 ┆ 32.0  ┆ 40.0  │\n",
+       "│ 4   ┆ 35.68  ┆ 35.0 ┆ 37.0   ┆ 37.0 ┆ 32.0  ┆ 40.0  │\n",
+       "│ …   ┆ …      ┆ …    ┆ …      ┆ …    ┆ …     ┆ …     │\n",
+       "│ 96  ┆ 31.315 ┆ 32.0 ┆ 34.0   ┆ 35.0 ┆ 27.5  ┆ 39.5  │\n",
+       "│ 97  ┆ 30.67  ┆ 31.0 ┆ 34.0   ┆ 35.0 ┆ 25.0  ┆ 41.0  │\n",
+       "│ 98  ┆ 31.55  ┆ 32.0 ┆ 34.0   ┆ 35.0 ┆ 27.5  ┆ 39.5  │\n",
+       "│ 99  ┆ 31.25  ┆ 32.0 ┆ 34.0   ┆ 35.0 ┆ 27.5  ┆ 39.5  │\n",
+       "│ 100 ┆ 31.105 ┆ 31.0 ┆ 34.0   ┆ 35.0 ┆ 25.0  ┆ 41.0  │\n",
+       "└─────┴────────┴──────┴────────┴──────┴───────┴───────┘"
+      ]
+     },
+     "execution_count": 19,
+     "metadata": {},
+     "output_type": "execute_result"
+    }
+   ],
+   "source": [
+    "pb.base_sequence_quality(\"example.parquet\").sort(by=\"pos\")"
+   ]
+  },
+  {
+   "cell_type": "markdown",
+   "id": "b519abbd",
+   "metadata": {},
+   "source": [
+    "#### Usage example - `polars.lazyframe.frame.LazyFrame` object"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 20,
+   "id": "1899ca01",
+   "metadata": {},
+   "outputs": [
+    {
+     "name": "stderr",
+     "output_type": "stream",
+     "text": [
+      "INFO:polars_bio:Table: example registered for path: ./example.fastq\n"
+     ]
+    },
+    {
+     "name": "stdout",
+     "output_type": "stream",
+     "text": [
+      "<class 'polars.lazyframe.frame.LazyFrame'>\n"
+     ]
+    },
+    {
+     "name": "stderr",
+     "output_type": "stream",
+     "text": [
+      "200rows [00:00, 212477.41rows/s]\n"
+     ]
+    },
+    {
+     "data": {
+      "text/html": [
+       "<div><style>\n",
+       ".dataframe > thead > tr,\n",
+       ".dataframe > tbody > tr {\n",
+       "  text-align: right;\n",
+       "  white-space: pre-wrap;\n",
+       "}\n",
+       "</style>\n",
+       "<small>shape: (101, 7)</small><table border=\"1\" class=\"dataframe\"><thead><tr><th>pos</th><th>avg</th><th>q1</th><th>median</th><th>q3</th><th>lower</th><th>upper</th></tr><tr><td>u64</td><td>f64</td><td>f64</td><td>f64</td><td>f64</td><td>f64</td><td>f64</td></tr></thead><tbody><tr><td>0</td><td>30.135</td><td>31.0</td><td>33.0</td><td>34.0</td><td>26.5</td><td>38.5</td></tr><tr><td>1</td><td>31.21</td><td>31.0</td><td>34.0</td><td>34.0</td><td>26.5</td><td>38.5</td></tr><tr><td>2</td><td>32.015</td><td>31.0</td><td>34.0</td><td>34.0</td><td>26.5</td><td>38.5</td></tr><tr><td>3</td><td>35.69</td><td>35.0</td><td>37.0</td><td>37.0</td><td>32.0</td><td>40.0</td></tr><tr><td>4</td><td>35.68</td><td>35.0</td><td>37.0</td><td>37.0</td><td>32.0</td><td>40.0</td></tr><tr><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td></tr><tr><td>96</td><td>31.315</td><td>32.0</td><td>34.0</td><td>35.0</td><td>27.5</td><td>39.5</td></tr><tr><td>97</td><td>30.67</td><td>31.0</td><td>34.0</td><td>35.0</td><td>25.0</td><td>41.0</td></tr><tr><td>98</td><td>31.55</td><td>32.0</td><td>34.0</td><td>35.0</td><td>27.5</td><td>39.5</td></tr><tr><td>99</td><td>31.25</td><td>32.0</td><td>34.0</td><td>35.0</td><td>27.5</td><td>39.5</td></tr><tr><td>100</td><td>31.105</td><td>31.0</td><td>34.0</td><td>35.0</td><td>25.0</td><td>41.0</td></tr></tbody></table></div>"
+      ],
+      "text/plain": [
+       "shape: (101, 7)\n",
+       "┌─────┬────────┬──────┬────────┬──────┬───────┬───────┐\n",
+       "│ pos ┆ avg    ┆ q1   ┆ median ┆ q3   ┆ lower ┆ upper │\n",
+       "│ --- ┆ ---    ┆ ---  ┆ ---    ┆ ---  ┆ ---   ┆ ---   │\n",
+       "│ u64 ┆ f64    ┆ f64  ┆ f64    ┆ f64  ┆ f64   ┆ f64   │\n",
+       "╞═════╪════════╪══════╪════════╪══════╪═══════╪═══════╡\n",
+       "│ 0   ┆ 30.135 ┆ 31.0 ┆ 33.0   ┆ 34.0 ┆ 26.5  ┆ 38.5  │\n",
+       "│ 1   ┆ 31.21  ┆ 31.0 ┆ 34.0   ┆ 34.0 ┆ 26.5  ┆ 38.5  │\n",
+       "│ 2   ┆ 32.015 ┆ 31.0 ┆ 34.0   ┆ 34.0 ┆ 26.5  ┆ 38.5  │\n",
+       "│ 3   ┆ 35.69  ┆ 35.0 ┆ 37.0   ┆ 37.0 ┆ 32.0  ┆ 40.0  │\n",
+       "│ 4   ┆ 35.68  ┆ 35.0 ┆ 37.0   ┆ 37.0 ┆ 32.0  ┆ 40.0  │\n",
+       "│ …   ┆ …      ┆ …    ┆ …      ┆ …    ┆ …     ┆ …     │\n",
+       "│ 96  ┆ 31.315 ┆ 32.0 ┆ 34.0   ┆ 35.0 ┆ 27.5  ┆ 39.5  │\n",
+       "│ 97  ┆ 30.67  ┆ 31.0 ┆ 34.0   ┆ 35.0 ┆ 25.0  ┆ 41.0  │\n",
+       "│ 98  ┆ 31.55  ┆ 32.0 ┆ 34.0   ┆ 35.0 ┆ 27.5  ┆ 39.5  │\n",
+       "│ 99  ┆ 31.25  ┆ 32.0 ┆ 34.0   ┆ 35.0 ┆ 27.5  ┆ 39.5  │\n",
+       "│ 100 ┆ 31.105 ┆ 31.0 ┆ 34.0   ┆ 35.0 ┆ 25.0  ┆ 41.0  │\n",
+       "└─────┴────────┴──────┴────────┴──────┴───────┴───────┘"
+      ]
+     },
+     "execution_count": 20,
+     "metadata": {},
+     "output_type": "execute_result"
+    }
+   ],
+   "source": [
+    "a_lazyframe = pb.read_fastq(\"./example.fastq\")\n",
+    "print(type(a_lazyframe))\n",
+    "pb.base_sequence_quality(a_lazyframe).sort(by=\"pos\")"
+   ]
+  },
+  {
+   "cell_type": "markdown",
+   "id": "cdb4aad6",
+   "metadata": {},
+   "source": [
+    "#### Usage example - `polars.dataframe.frame.DataFrame` object"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 21,
+   "id": "7830b8aa",
+   "metadata": {},
+   "outputs": [
+    {
+     "name": "stderr",
+     "output_type": "stream",
+     "text": [
+      "INFO:polars_bio:Table: example registered for path: ./example.fastq\n",
+      "200rows [00:00, 177236.59rows/s]"
+     ]
+    },
+    {
+     "name": "stdout",
+     "output_type": "stream",
+     "text": [
+      "<class 'polars.dataframe.frame.DataFrame'>\n"
+     ]
+    },
+    {
+     "name": "stderr",
+     "output_type": "stream",
+     "text": [
+      "\n"
+     ]
+    },
+    {
+     "data": {
+      "text/html": [
+       "<div><style>\n",
+       ".dataframe > thead > tr,\n",
+       ".dataframe > tbody > tr {\n",
+       "  text-align: right;\n",
+       "  white-space: pre-wrap;\n",
+       "}\n",
+       "</style>\n",
+       "<small>shape: (101, 7)</small><table border=\"1\" class=\"dataframe\"><thead><tr><th>pos</th><th>avg</th><th>q1</th><th>median</th><th>q3</th><th>lower</th><th>upper</th></tr><tr><td>u64</td><td>f64</td><td>f64</td><td>f64</td><td>f64</td><td>f64</td><td>f64</td></tr></thead><tbody><tr><td>0</td><td>30.135</td><td>31.0</td><td>33.0</td><td>34.0</td><td>26.5</td><td>38.5</td></tr><tr><td>1</td><td>31.21</td><td>31.0</td><td>34.0</td><td>34.0</td><td>26.5</td><td>38.5</td></tr><tr><td>2</td><td>32.015</td><td>31.0</td><td>34.0</td><td>34.0</td><td>26.5</td><td>38.5</td></tr><tr><td>3</td><td>35.69</td><td>35.0</td><td>37.0</td><td>37.0</td><td>32.0</td><td>40.0</td></tr><tr><td>4</td><td>35.68</td><td>35.0</td><td>37.0</td><td>37.0</td><td>32.0</td><td>40.0</td></tr><tr><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td></tr><tr><td>96</td><td>31.315</td><td>32.0</td><td>34.0</td><td>35.0</td><td>27.5</td><td>39.5</td></tr><tr><td>97</td><td>30.67</td><td>31.0</td><td>34.0</td><td>35.0</td><td>25.0</td><td>41.0</td></tr><tr><td>98</td><td>31.55</td><td>32.0</td><td>34.0</td><td>35.0</td><td>27.5</td><td>39.5</td></tr><tr><td>99</td><td>31.25</td><td>32.0</td><td>34.0</td><td>35.0</td><td>27.5</td><td>39.5</td></tr><tr><td>100</td><td>31.105</td><td>31.0</td><td>34.0</td><td>35.0</td><td>25.0</td><td>41.0</td></tr></tbody></table></div>"
+      ],
+      "text/plain": [
+       "shape: (101, 7)\n",
+       "┌─────┬────────┬──────┬────────┬──────┬───────┬───────┐\n",
+       "│ pos ┆ avg    ┆ q1   ┆ median ┆ q3   ┆ lower ┆ upper │\n",
+       "│ --- ┆ ---    ┆ ---  ┆ ---    ┆ ---  ┆ ---   ┆ ---   │\n",
+       "│ u64 ┆ f64    ┆ f64  ┆ f64    ┆ f64  ┆ f64   ┆ f64   │\n",
+       "╞═════╪════════╪══════╪════════╪══════╪═══════╪═══════╡\n",
+       "│ 0   ┆ 30.135 ┆ 31.0 ┆ 33.0   ┆ 34.0 ┆ 26.5  ┆ 38.5  │\n",
+       "│ 1   ┆ 31.21  ┆ 31.0 ┆ 34.0   ┆ 34.0 ┆ 26.5  ┆ 38.5  │\n",
+       "│ 2   ┆ 32.015 ┆ 31.0 ┆ 34.0   ┆ 34.0 ┆ 26.5  ┆ 38.5  │\n",
+       "│ 3   ┆ 35.69  ┆ 35.0 ┆ 37.0   ┆ 37.0 ┆ 32.0  ┆ 40.0  │\n",
+       "│ 4   ┆ 35.68  ┆ 35.0 ┆ 37.0   ┆ 37.0 ┆ 32.0  ┆ 40.0  │\n",
+       "│ …   ┆ …      ┆ …    ┆ …      ┆ …    ┆ …     ┆ …     │\n",
+       "│ 96  ┆ 31.315 ┆ 32.0 ┆ 34.0   ┆ 35.0 ┆ 27.5  ┆ 39.5  │\n",
+       "│ 97  ┆ 30.67  ┆ 31.0 ┆ 34.0   ┆ 35.0 ┆ 25.0  ┆ 41.0  │\n",
+       "│ 98  ┆ 31.55  ┆ 32.0 ┆ 34.0   ┆ 35.0 ┆ 27.5  ┆ 39.5  │\n",
+       "│ 99  ┆ 31.25  ┆ 32.0 ┆ 34.0   ┆ 35.0 ┆ 27.5  ┆ 39.5  │\n",
+       "│ 100 ┆ 31.105 ┆ 31.0 ┆ 34.0   ┆ 35.0 ┆ 25.0  ┆ 41.0  │\n",
+       "└─────┴────────┴──────┴────────┴──────┴───────┴───────┘"
+      ]
+     },
+     "execution_count": 21,
+     "metadata": {},
+     "output_type": "execute_result"
+    }
+   ],
+   "source": [
+    "a_lazyframe = pb.read_fastq(\"./example.fastq\")\n",
+    "a_dataframe = a_lazyframe.collect()\n",
+    "print(type(a_dataframe))\n",
+    "pb.base_sequence_quality(a_dataframe).sort(by=\"pos\")"
+   ]
+  },
+  {
+   "cell_type": "markdown",
+   "id": "ddf5da9d",
+   "metadata": {},
+   "source": [
+    "#### Usage example - `pandas.core.frame.DataFrame` object"
+   ]
+  },
+  {
+   "cell_type": "code",
+   "execution_count": 22,
+   "id": "56817174",
+   "metadata": {},
+   "outputs": [
+    {
+     "name": "stderr",
+     "output_type": "stream",
+     "text": [
+      "INFO:polars_bio:Table: example registered for path: ./example.fastq\n",
+      "200rows [00:00, 74651.67rows/s]"
+     ]
+    },
+    {
+     "name": "stdout",
+     "output_type": "stream",
+     "text": [
+      "<class 'pandas.core.frame.DataFrame'>\n"
+     ]
+    },
+    {
+     "name": "stderr",
+     "output_type": "stream",
+     "text": [
+      "\n"
+     ]
+    },
+    {
+     "data": {
+      "text/html": [
+       "<div><style>\n",
+       ".dataframe > thead > tr,\n",
+       ".dataframe > tbody > tr {\n",
+       "  text-align: right;\n",
+       "  white-space: pre-wrap;\n",
+       "}\n",
+       "</style>\n",
+       "<small>shape: (101, 7)</small><table border=\"1\" class=\"dataframe\"><thead><tr><th>pos</th><th>avg</th><th>q1</th><th>median</th><th>q3</th><th>lower</th><th>upper</th></tr><tr><td>u64</td><td>f64</td><td>f64</td><td>f64</td><td>f64</td><td>f64</td><td>f64</td></tr></thead><tbody><tr><td>0</td><td>30.135</td><td>31.0</td><td>33.0</td><td>34.0</td><td>26.5</td><td>38.5</td></tr><tr><td>1</td><td>31.21</td><td>31.0</td><td>34.0</td><td>34.0</td><td>26.5</td><td>38.5</td></tr><tr><td>2</td><td>32.015</td><td>31.0</td><td>34.0</td><td>34.0</td><td>26.5</td><td>38.5</td></tr><tr><td>3</td><td>35.69</td><td>35.0</td><td>37.0</td><td>37.0</td><td>32.0</td><td>40.0</td></tr><tr><td>4</td><td>35.68</td><td>35.0</td><td>37.0</td><td>37.0</td><td>32.0</td><td>40.0</td></tr><tr><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td><td>&hellip;</td></tr><tr><td>96</td><td>31.315</td><td>32.0</td><td>34.0</td><td>35.0</td><td>27.5</td><td>39.5</td></tr><tr><td>97</td><td>30.67</td><td>31.0</td><td>34.0</td><td>35.0</td><td>25.0</td><td>41.0</td></tr><tr><td>98</td><td>31.55</td><td>32.0</td><td>34.0</td><td>35.0</td><td>27.5</td><td>39.5</td></tr><tr><td>99</td><td>31.25</td><td>32.0</td><td>34.0</td><td>35.0</td><td>27.5</td><td>39.5</td></tr><tr><td>100</td><td>31.105</td><td>31.0</td><td>34.0</td><td>35.0</td><td>25.0</td><td>41.0</td></tr></tbody></table></div>"
+      ],
+      "text/plain": [
+       "shape: (101, 7)\n",
+       "┌─────┬────────┬──────┬────────┬──────┬───────┬───────┐\n",
+       "│ pos ┆ avg    ┆ q1   ┆ median ┆ q3   ┆ lower ┆ upper │\n",
+       "│ --- ┆ ---    ┆ ---  ┆ ---    ┆ ---  ┆ ---   ┆ ---   │\n",
+       "│ u64 ┆ f64    ┆ f64  ┆ f64    ┆ f64  ┆ f64   ┆ f64   │\n",
+       "╞═════╪════════╪══════╪════════╪══════╪═══════╪═══════╡\n",
+       "│ 0   ┆ 30.135 ┆ 31.0 ┆ 33.0   ┆ 34.0 ┆ 26.5  ┆ 38.5  │\n",
+       "│ 1   ┆ 31.21  ┆ 31.0 ┆ 34.0   ┆ 34.0 ┆ 26.5  ┆ 38.5  │\n",
+       "│ 2   ┆ 32.015 ┆ 31.0 ┆ 34.0   ┆ 34.0 ┆ 26.5  ┆ 38.5  │\n",
+       "│ 3   ┆ 35.69  ┆ 35.0 ┆ 37.0   ┆ 37.0 ┆ 32.0  ┆ 40.0  │\n",
+       "│ 4   ┆ 35.68  ┆ 35.0 ┆ 37.0   ┆ 37.0 ┆ 32.0  ┆ 40.0  │\n",
+       "│ …   ┆ …      ┆ …    ┆ …      ┆ …    ┆ …     ┆ …     │\n",
+       "│ 96  ┆ 31.315 ┆ 32.0 ┆ 34.0   ┆ 35.0 ┆ 27.5  ┆ 39.5  │\n",
+       "│ 97  ┆ 30.67  ┆ 31.0 ┆ 34.0   ┆ 35.0 ┆ 25.0  ┆ 41.0  │\n",
+       "│ 98  ┆ 31.55  ┆ 32.0 ┆ 34.0   ┆ 35.0 ┆ 27.5  ┆ 39.5  │\n",
+       "│ 99  ┆ 31.25  ┆ 32.0 ┆ 34.0   ┆ 35.0 ┆ 27.5  ┆ 39.5  │\n",
+       "│ 100 ┆ 31.105 ┆ 31.0 ┆ 34.0   ┆ 35.0 ┆ 25.0  ┆ 41.0  │\n",
+       "└─────┴────────┴──────┴────────┴──────┴───────┴───────┘"
+      ]
+     },
+     "execution_count": 22,
+     "metadata": {},
+     "output_type": "execute_result"
+    }
+   ],
+   "source": [
+    "a_lazyframe = pb.read_fastq(\"./example.fastq\")\n",
+    "a_pandas_dataframe = a_lazyframe.collect().to_pandas()\n",
+    "print(type(a_pandas_dataframe))\n",
+    "pb.base_sequence_quality(a_pandas_dataframe).sort(by=\"pos\")"
+   ]
+  }
+ ],
+ "metadata": {
+  "kernelspec": {
+   "display_name": "venv",
+   "language": "python",
+   "name": "python3"
+  },
+  "language_info": {
+   "codemirror_mode": {
+    "name": "ipython",
+    "version": 3
+   },
+   "file_extension": ".py",
+   "mimetype": "text/x-python",
+   "name": "python",
+   "nbconvert_exporter": "python",
+   "pygments_lexer": "ipython3",
+   "version": "3.12.10"
+  }
+ },
+ "nbformat": 4,
+ "nbformat_minor": 5
+}
diff --git a/docs/notebooks/example.csv b/docs/notebooks/example.csv
new file mode 100644
index 00000000..852077c0
--- /dev/null
+++ b/docs/notebooks/example.csv
@@ -0,0 +1,201 @@
+name,description,sequence,quality_scores
+SRR9130495.1,D00236:723:HG32CBCX2:1:1108:1330:1935/1,NCAATACAAAAGCAATATGGGAGAAGCTACCTACCATGCTTAAAAACGCCAATGAGCAGNGATTTGTCANCNNNNNNNNCNNNNNNNNTNNTANNANNCTC,"#4BDFDFFHGHGGJJJHIIIIGGIIJGJJGIIIIBHIJJJIIJIJJIJDHIGGGIJJJI#-@AEHGEFF#,########,########+##++##+##+2<"
+SRR9130495.2,D00236:723:HG32CBCX2:1:1108:1472:1938/1,NGTCAAAGATAAGATCAAAAGGCACTGGCTTACCTGATTAAGAAATTGTGTAGTCCAACATCAAAATACNTNTNNNNNAGAGNCANGNCAAGCNNANNAAT,"#1=DDDDD>DHFH@EFHHGHGGFGIIIGIGGGGIIGIIDDCHIIIIIID@FEGGGIIIIICHIIIIIIG#-#-#####,,;;#,5#,#,,8<?##,##++8"
+SRR9130495.3,D00236:723:HG32CBCX2:1:1108:1728:1948/1,GTTTTCCTCTGGTTATTTCTAGGTACACTGGAAAAGAGTTTGCATTAAAGATTATAGACAAAGCCAAATGCTGTNGNAAGGTACAGTATACACAACTGCTA,@@@DDDFFHHHFHBHIIGJIJIIJIIIEHGIGIJJIIGGIIIJIIJIJIIIIIHIJJIIJJIGHGIJJIGGHC=#-#-5?EBEFFFDEEEFEAEDBCCCDC
+SRR9130495.4,D00236:723:HG32CBCX2:1:1108:1635:1961/1,GGGAGGCGCCCCGACCGGCCAGGGCGTGAGCCCCAGCCCCAGCGCCATCCTGGAGCGGCGCGACGTGAAGCCAGATGAGGACCTGGCGGGCAAGGCTGGCG,CCCFFFFFHHHHGHIIIGIIJIIIJJGHFFFFDDDDDDDDDDDDBDDDDBDCCDDDDDDDDDDDBDDDDACDDDDDDDDDDDDDCDDDDDDDDDDDDDDDD
+SRR9130495.5,D00236:723:HG32CBCX2:1:1108:1605:1988/1,CACTCCGCCACTACAGCAGTCCCCCAGTGTCATCCGGAGACTTGTGACCATCTCGCCCAACAATAAGCCCAGTGAGTAGGAGGAAAGTCTGGAAATGGGTA,"++=A1A:1ADA<;FFDC?;CG<F;::1CFIFCFABF?)77/*8.=FEFFI@38=CC=8<BD=B;36;6.,5?(-:3>5@A:AB@8>@:@A@9(:((+(834"
+SRR9130495.6,D00236:723:HG32CBCX2:1:1108:2392:1965/1,CGATAAAGGACTTTCAGTCAACCAACTAGATAATGACCACTGGGCACCCATTCATTATGCATGCTGGTAAATAAATTATTCTGTTCAGGAACATTGAACTC,CC@DDDBDFFHHHJJIJJIIJIJJJIIIHGIGGHCGGIGHH<FGHHIGEFHHIGIHHGHIIJJJJEGIGIEEHHHGHHHGFFFDDFFEEEEEDDA@DCCCC
+SRR9130495.7,D00236:723:HG32CBCX2:1:1108:3536:1968/1,TGGCAATGGTGTTTCTTCTTATATGATGCTTATATCCAAGGGAGGGCCACATGGAAACTCCAGGGCTCCTGGGTCATGGCAATGGAGTGAGTGGAAAGCTA,@CCFFFFFHHHHHIGIJJIJIJJJIJJJJJJJJJJJJGGIJIIJJJJJJJJJJIJIJJJIIJIJJHHHHFFFFFEEEDDDDDDDDDDDDDDDDCDDDBDDC
+SRR9130495.8,D00236:723:HG32CBCX2:1:1108:3726:1969/1,TATTTCTTACTCTTTCAGATGTTACCCTCCCCCGACTTAAGGCCTTCATACCTCAGCTGCTGTCACGGCTGCATATTGAAGCACTTCTCCATGGAAACATA,CCCFFFFFHHHHHJJJJGGIIJIJJHGJJJJJJJJJHIIJHDGGIJJJIIGIJJJJJIIJJJIJJHHHFFDDEDDDEEDDCDDDDDDDDDCDDDDDCDDDD
+SRR9130495.9,D00236:723:HG32CBCX2:1:1108:3936:1939/1,NAAACTTTGATGTCCTAGCCCCAGGAGATGGGCACTGGGAAAGTGGTTGATCGGAAAGTAGAGCTTGAANANGNNNNNGGTCNTGAACTCCATNNACNGCT,"#4=DFDFFHHHHHIJJJHGIIIJJJJGIIJEIIIIJFGHFHJJHIJGJIIJJJIJJJGGIIEHIGGHHH#,#,#####,,;?#,5??@CCDDD##+2#+8?"
+SRR9130495.10,D00236:723:HG32CBCX2:1:1108:3767:1949/1,CTGTCAGTACAGTGGGACCCACAGAACAGACTGGATTTTGCAACCTTCCAAGGCAGTGTCTACTACAAGGTGTGNCNGTGGAGAGGTTTCTCAGAGAAGCC,"B@@DDBDFDFHHC<F<BGHGBFHGIJIGEGIJIGFAFHCDGIHCGEHEE@AGHGIJHIIIHGDGE@EIGH;?AA#,#(5=?@?C?BC?CAAC>AACC??A<"
+SRR9130495.11,D00236:723:HG32CBCX2:1:1108:4089:1977/1,CATTCCAACCAGCCGCTTAAAGTTTCTAAAAGAAGCTGGTCATGGAACCCAGAAGGAGGAGATACCTGAGGAGGAATTAGCAGAGGATGTTGAAGAGATTG,CCCFFFDFHHHHHJIJJJJIIJJJJJJJJJJJIIGJJJIGHGIJJIJJIJJIIFHGHIJJGHEHHFCEFFDEDDBDDDDDDDDDDDBACDDDDDDDDDDDD
+SRR9130495.12,D00236:723:HG32CBCX2:1:1108:6197:1936/1,NCTTAAAGGCAAGGTGCTCGGCTTCCGCTATCAAGACCTCCGACAGAAAATCCGGCCTGNGGCTAAAGANCNNNNNNNNANNNNNNNNCNNGGNNCNNGGC,"#1BDFDEFGHHHHIJJJJJJIJJJJJJJJJJIJJIGIJJIJJJIJJJJHIJJHHHFFDC#,;?BBDDDD#,########+########+##++##+##++8"
+SRR9130495.13,D00236:723:HG32CBCX2:1:1108:6415:1939/1,NTGTGTATGGGGATGAGGAAGGATATTAATATGTTCTATTTGAGATTTAGGGATTACATTTGTTTTTGCNCNCNNNNNTTTTNTCNTCATTTGNNGTNAAT,"#1:ADDDFHGGHFGGBHIGGIIJJEIIIJJIJIJJJFGJIIHGHGDGHJGHIHIIIIJJIIHFHIIJJJ#-#-#####,,;?#,;#,8?DDEE##,+#+2<"
+SRR9130495.14,D00236:723:HG32CBCX2:1:1108:6361:1952/1,TCAGATCTTATTTTAATAGTTGACTTTACCTCTTCTTTGACTTCCTCTTCCTCGGTCTCAGTAGATATAGATGGTACCTTGGGCTTATGCCATGAGATCTG,CCCFFFFFHHHHDHIIIIJJJJJJJJJJHIIIJJJJJJJIHJHJII>GHIEGHIIIIJJJIJJIHHIJJJIJIGHIJJGJJHFHHFFDCFFEDCEDCCDEC
+SRR9130495.15,D00236:723:HG32CBCX2:1:1108:6263:1960/1,CAATATCTGACTGAATGGGCCCATTTTCATAATATTCTGAAACTGTTCATACATGTCTCGCAATGTAAACTGACCTGAAATGCAATACAAAAAAATTCAGA,CCCFFFFFHHGHGGGIIIIJJIJIJJIIIIIIIIEIHGGIEGGHGIJJIJJJCECGHIIIJJJJJIFGHIIHGIIJJHHGEFHDFFFFFCCCDDBBCCDCA
+SRR9130495.16,D00236:723:HG32CBCX2:1:1108:6338:1988/1,AGACACTAAAATGCCATGTATGAGACTACATAGACATACCAATTTACAACACAAACACATGAAATATACATGAGAAAACATTAACTTACTTCCAGTTGGGA,C@CFFDDDHGHHHIIIIHJJIIHIHGIJJJJJIJJJIJIIHEHIIJJJJJJIJJIIIIIJJDHIJIJGIJIJJIJJHHGGHFFFFFFFEEEDCCC@ACCBA
+SRR9130495.17,D00236:723:HG32CBCX2:1:1108:6742:1944/1,NGAAACACTCTTTTTCTGGAATTTGCAAGTGGAGATTTCAGCCGCTTTGTGGTCAATGGTAGAAAAGGAAATATNTNCATATAAAAACTAGACAGAATGAT,"#1BDFDFFHGHGHJJJJJJJJHIJHHIJIIJJIJJGIJJIJIIJJGIJIHIJJJIIJJJHIEIIJJJJIHDEFH#,#,5=ADEEEDCDDDDDDDCDD5@CD"
+SRR9130495.18,D00236:723:HG32CBCX2:1:1108:7076:1942/1,NGTCTAAGAATGAAGTGCTTATGGTCAACATAGGCTCCCTGTCGACAGGAGGAAGAGTTAGTGCAGTCAAGGCTNANTTGGGCAAAATTGTTTNNACCAAT,"#1:B:BDDHHFFHIEGGIGIDEHGEEGIGHIIIFACHIGIGCFGEHIGGHHGHGH@DCGGIDEIIIIFFHHAEE#,#,5=@BBC@BCCCCCCC##,+8?BC"
+SRR9130495.19,D00236:723:HG32CBCX2:1:1108:7440:1957/1,CACCTGATGTCCCACAGTCCTCATAGACACTAGCACTGACTGCTGGCCATCGTCTCAGCCAGATGATGTTGACCTGCTAGCTTTTCAATTAAATTATTAAA,+=144=DD>D4CCD?E@AECFFIIIIEI?E+??;3EBDECEIBEECDIEIIADDDDEIDCDCA;=A@CECE7ACD=(;;A@DA@A@A:ADAAAD>AADBB>
+SRR9130495.20,D00236:723:HG32CBCX2:1:1108:7363:1977/1,ACTCATAGAGTTGAAGATTCCCTTTCATAGAGCAGGTTTGAAACACTCTTTCTGGAGTATCTGGATGTGGACATTTGGAGCGCTTTGATGCCTACGGTGGA,CCCFFDDDFHHHHJJJIJJJJHHIIHGIJIJJJIGGHGIJIJJIIIJJJJJIJIGBFDHIIJIJGIJIGGCHGGIJHIIHHHFECDECEEDCDDCBD9?B?
+SRR9130495.21,D00236:723:HG32CBCX2:1:1108:7298:1979/1,AACCGTCGCCAGGTACCATCCCAGAGAACTCTGTCTTCCTTACTTATAGCCAAGTTGCCGGCAGATCACAGCTGCATGCTTATCGGTCCATCCGTCATCGC,BCCDDDFFGGFGFJIBBHHIJJIIHHIIIGJIIHIIJJJIIEIGHJIIJJJJIIHHGIJFGHGFDDCEECDDDDDDDDDDEDDDDDDDBDEDDD<BBDDDB
+SRR9130495.22,D00236:723:HG32CBCX2:1:1108:7487:1988/1,TGAGAAAGCCTTCATCACATACAGAACACTTCTAAACCACAAAAAAATTCATCTTGGAGAAAAGCCCTATAAATGCGATGTGTGTGAGAAATCTTTTAACT,CCCFFDDEFHHGHJIEGGHGIJEIGHECGIIJIIIIIIGHGGEIIIJJJIGGFGGH@FECHDHCHHHFFDCEECDCDBDBDDED@ACCDDDDCDACC>CCC
+SRR9130495.23,D00236:723:HG32CBCX2:1:1108:7307:1995/1,TAATTTGGTATATGTCTTTTTAAAGGCATTTTTATTAGATATTTCCTTAATTTACATTTCAAATGTTATCCCCAAAGCCCCCTATAATCTACCCCTGCCTT,;?7DD?;DBFHHFIA<DBEC<EHH@3AC?C@HGE@?FGAFHDBA*1?4FBCGAGHGEB99B49D<F9BF488CBD9)7@AE:/;7;@A?@@@3;=?=;;(;
+SRR9130495.24,D00236:723:HG32CBCX2:1:1108:7539:1956/1,TTGTTTTGACCAGGCACGGTGGCTCACGCCTGTAATCCCAGCACTTTAGATCGGAAGAGCACACGTCTGAACTCCAGTCACCACTTCGAATCTCGTATGCC,?8?=BA?DFDFFB:?F@<8AFBFDFDBFF@?BBGGEGB9?FGIIF<??CFEAEFFIDFFIFFF@9BDDCC;6;65@>;A@AABBB@B?2<58+:?<<9<@:
+SRR9130495.25,D00236:723:HG32CBCX2:1:1108:7870:1955/1,CTATCCCGTCGGGTGACTGTTTCCTGCTTTGCAGTTATTCAGTGGCAGAGCGTGGCGCTCTAATTTCTGCTTTCCTCTTTCCTGCAGATTGTGTGCTACAT,CCCFFFDFFHHFHBHGJIIIHGIIIJJIJIIIIJHIIIIEIJJIIJJJJIJIJIJDFEDDDCEEEEEEDDDDDDDDCDDDCDDDDDDDCDDDCDDDDDDDD
+SRR9130495.26,D00236:723:HG32CBCX2:1:1108:8157:1994/1,GAAGTGCTCTTCGTTACTACTTAAATCCCCCTGGGCATGTTTCATTATTTTACAATTTGTGCAGAACCCTATCCAAACACACATGGAGTACAAATGACTTC,CCCFFDDDDHHDHHIGIIBIHHHJJJ@FGG<FEGHGDEIGIIIIIDBBFGGB@GFGGEFHGGHEC@DCEGGDEHEHDBEFEDDEE>A?@CCCCCC@CCCDD
+SRR9130495.27,D00236:723:HG32CBCX2:1:1108:8703:1937/1,NATAAAAAAATAACATCCTTTCCTCCTAATAGCTTAATTATTTGAAAAAAAATATTTTCNAATCACATGNANNNNNNNNTNNNNNNNNTCTTTNNTNNCCT,"#1=DFDDDHHHHHIIJJJJJFIJJJIGIEGIIJJJHHIJJJJJIIJIIIIIJEHEHHHA#,;??AEDDC#,########,########++8??##+##(+2"
+SRR9130495.28,D00236:723:HG32CBCX2:1:1108:8702:1991/1,CTCAGAGATTAAAAATGAATAACGCCTGCCGGCCAATGAGCGGACTCACAGTCCCTGTTTGTTTGTAAGCTAGGTGATTTTCAATCCACAGGGCAGGCTGA,@@@DFDFFGGDHFGIIBGEHJIIIBGIIIJJIIJIJIIFGGEGIJJJHGGHHHDCFFDDDEDEDDDDDCDDDCBDDACDEDEDDDDCCCCD<?BBBBDBDB
+SRR9130495.29,D00236:723:HG32CBCX2:1:1108:8950:1937/1,NGGTGTGCAACGGCGTGATCACAGCTCACTGCAATCTCAACCTCCCAGGCTCCTGTTATNCTCCCACCTNANNNNNNNNANNNNNNNNGACTANNGNNATG,"#1=DDDDFHHHFHJJJJJJJJIIGIJGIJIJIJIJIJEHDHIIJIJJIIIJJJJGHGGH#,;BBDEEDD#,########,########++8?@##+##++<"
+SRR9130495.30,D00236:723:HG32CBCX2:1:1108:9308:1960/1,CATCTCCTCTGTGCGTTGCAGTGAGTATGGCTTTGCTGAGAAGGTGGTGGAGGGAATGTTCATTGTGGTCAACTCCATCACCATCAAGATCCACTCCAAGG,CCCFFFFFHHHHHFIJJJJJJJJJJJIJIJJJJIHIIFHJJJIJIIFGIGAGIFEHECDHGIHFHHHHFFFFEDEEEEEEDDDDDDDDDDDDDDDDDDDDD
+SRR9130495.31,D00236:723:HG32CBCX2:1:1108:9667:1990/1,CCACAGGAAAAGAGAATCTAAAAGAAATATGGGAGAAGTGATAGCCTTGTGACAAATTCCTCCAGTGGGGAATTTAGCCAGAACTTTTACCTTTCCTATAA,CCCFFDDEHHHHHJJJJJJJJJJJJJIIIGGIIGIHIIIJJJJJIJEGGHJJIJJJJJJJIJIJJGGIJHHGFFFFFFEEEEEDDDDDDDCDDDDDDDDCC
+SRR9130495.32,D00236:723:HG32CBCX2:1:1108:9793:1965/1,GTTGTTACATGTTCATTCTCTCTATTTGTATCTTCTTTCTCTCTCACATCTGCTCCTCTGCCTAGACACTCCTGAGGAAAACCCTTATTTCCCTACATACA,@@@FFDDFHHGHDFFGIIIJGIIBHJJJJEIJIJIJIGGIIIDIJIIGHGIIIJIIHIIIJIIJDIJIJHHIIDGIFGGGIGGHHFFFDEFEDEEDEDDCD
+SRR9130495.33,D00236:723:HG32CBCX2:1:1108:10297:1993/1,TTCACTTTTGGAATTTTAGGCATTCTAATAGATGTATAGTGGTATCTCATTGTGGTTTTGATTTGCATTTCTTTAATGAAATTATGTTGAGCATTTTTTCA,@@@F?DADFDHHFGGIGIIFHJIGIGIHGIJJJJJJBGEF?CGF>GII@GIFGFE???BFBBEHIGGIEEHIHIGGHHGIHA3?CH;?@CB@DCCEDEDD3
+SRR9130495.34,D00236:723:HG32CBCX2:1:1108:10535:1962/1,AATACAGAAAAGTTAAGAGCCAGCCCCAGGCGGATTGGATGAATAGGTTGCATCTCTTTCTTGCTTATATCAAATGCCTCTTGGCAGGCTCCTTGGGAATT,???BD:A:<?CACFGIIIB;A@D=+22+1:)1:D:?FD)/=<F@H=FGC@AGCE7=?E>3=?B:;?;;CA;;;A3-5>5-5:(::@8/2?8?9>>3(83(+
+SRR9130495.35,D00236:723:HG32CBCX2:1:1108:11147:1968/1,GCTGCCTTCTCCCCTCAAGGATGCAGTGGAAGTGTCAACCTGGAGAAGATGCTACACGATGCAGGAGGTGAACTCGGCCCTCAGTAAAATCCAGCTGGTGG,CCCFFFDFHHHGHJFEGIHEGHIGIIGCCGGGIIJJIJJGGGGHCGIF>DGHIIIEHHGIIJJDBGHFHFCCFFFDDCDDDDBDDDCCDEDA:CACD@CDD
+SRR9130495.36,D00236:723:HG32CBCX2:1:1108:11124:1986/1,GACAGGGTTTCACCATGTTAGCCAGGACGGTCTTGATCTCCTGACCTCGTGATCCGCCTGTCTCGGCCTCCCAAAGTCCTGGGATTACAGGCGTGAGCCAC,CCCFFFFBFFFHGGHGHIHIIGIJFJJJIJHIIIFGHGGIIGEGHIH@@FGGIJIIGGIHIEEHEEFFDDCCCCBDDACCDCDBAACCDDDBDDDDBDDCC
+SRR9130495.37,D00236:723:HG32CBCX2:1:1108:11773:1947/1,TACCTGCCTCTGCCTCTCGAGTGCTGGGATGAAAGATGTGCACACCCCCACCACCACCACCACCACTGCCTGGCNCNGTTTTTGATTTCTTATTCTCCAGA,"CCCFFFFFHGHHHJIJIJIIEHIJJIJJIJJIHIHJJIGFIIIIJBHHGFF>HGIJIEHHHFGDEEEEEECC?B#,#,,5?<?BDCCD@@CCDCDDCCDCA"
+SRR9130495.38,D00236:723:HG32CBCX2:1:1108:12184:1941/1,NGTGTGTATATATTACTGCTCATTAACGGTGCACGTGGTCACCCAAGAGCTCTGATAGCAAGGTACAAAGAGATNNNTGTTGTTTTCACGCCCNNTANCAC,"#11ABDDDHHDFHIIIIIIIIHIIHFHFHIIIIIIGGGIIIGDFFHIIIIIHIIIIIIIIIIIHGCHIIGBEEH###,,;?ACDDDDDDDDBB##,+#+28"
+SRR9130495.39,D00236:723:HG32CBCX2:1:1108:12711:1965/1,TTCCAGAACATCCCCAAACTTTCCAAGGTTTGGTTACACTGTGAGACGTTCATCTGCGACAGTGAGAAGCTCTCCTGCCCCGTGGTGAGGGTCCTGGCTCC,@@@DDFFDHFHHFIIJJJJIJJHGEHJJFIHHEHGHHHIIIJIIHJJIHIJDGIIIIIJJJJJHHHGHEFFFFFEEEEDDDD?BDBBCDDDDDDACCDDDB
+SRR9130495.40,D00236:723:HG32CBCX2:1:1108:13153:1937/1,NGTGTACTTGACTAACTCCAAAGTTGTCAGTCGAAAGTGACTTTCCTGTCACAGATCATNCGGTGTTTGNTNNNNNNNNANNNNNNNNTNNAANNTNNCAG,"#1:BDD?DHHHHHIGIIFCE;4CHHGGI>@HF1CGBGHC<DHIGHIIGG>DD<BH@GGI#-71CFHIGH#-########,########,##,,##+##++2"
+SRR9130495.41,D00236:723:HG32CBCX2:1:1108:13100:1949/1,CTAAAACATCGAGCTTCAAATGTCTTCCTAGTATACCGCACGAATGTTTCTTTTACCATATTTTCTGGAGTGTTNGNTTAGTTTTTCCTCAAAGAGGTGTA,"@@@FFEDDHHHFHJJIJJGHJIGBFHHIHJIGIJEGJJJJFIIIJJGEIHHHIIIHIJJJJJIFHIHHHHFFDD#,#,5=?BDCCBCCCDDDCDDDBCACC"
+SRR9130495.42,D00236:723:HG32CBCX2:1:1108:13438:1959/1,CTTCCGATTCCATTCGATGATGATGGCATTCGATTCCTTTCAATCATTCCCTTTGATTCCATTCAAAGGTGATTTCATTCAAGTCCATTCGATAATTGCAT,CCCFFDFFHGHHHIJJJJIIJJJIGGHEEGIIIIIIIFGJJIIJIJJIJIIJJJJIJJJIJJJIIGIHGIJGIEIJGIJIIJIHGIFEHFHHHFDBFFFCC
+SRR9130495.43,D00236:723:HG32CBCX2:1:1108:13715:1971/1,TTTTGCTGCAAACCTGTCGATATCAACATTTCTGCTTCATGCTTCAGGTGGGTTTTCTCAGATGTATGCCTGTGTGTGCGACTGGCTGGGCTTTTCATACA,CCCFFFEDDHHHHIGIGHJIIGGIHIJHEHIIJJJJJIFIJIGIIIJIHHIJIJJIJJIHHFGIIIIGIJHHHHEEFFFFACBDDDDDDBDDBDDDDEEDC
+SRR9130495.44,D00236:723:HG32CBCX2:1:1108:13659:1977/1,GTATACAATATATGGTTTGTGAACTTTGATATTTCATGTAGAGTATAAAATATATATTTGGGGTACTTTGATATTTTATGTACAGTATATAATCTATGTTT,CCCFFFFFHHHGHJJHIIIJJJIIJJJJJJJJJJJJIJHJJJIJJJJJJIJJJJJJHIJJJJIGHJJJJJIJJGHIJJJJJIJIJHHHHHHGHFDFFFFFE
+SRR9130495.45,D00236:723:HG32CBCX2:1:1108:13735:1988/1,TGGCAAGGGCTGCCCTCGTCCACATCCTGGGGTGTGTTAATGGGACTGTTGCTGTCTAATGGGAGTGCTTTGCCTGAGGGAAGCCTGCATCTCACATCCAC,"?@@DDBD?FD?DDHEG=E@FBHD?<FH@FGHG:@DB(9==BFE2C@>FF7=DEG.?AAC?3@EED;6@;>(-;@AC?31(,5?<?C8?CCA@>(4::A>AC"
+SRR9130495.46,D00236:723:HG32CBCX2:1:1108:14226:1948/1,AACCTGCACCCAGAATGGCAGGAGGTCCTGGTGGCCCAGGGGGTCCTGGTGGTCCAGGAACACCAGGTCTCCCANANCCAGGTGGCCCAGGCAGGCCTGGA,??1D1BDDHFHHBBHGGGAFG)AF1:?CEGD@BGAFDGIGGB'5;CE77?=???>>C<A@??C=9<<CCC:>C3#+#++228>>28((2(<??<95@AB<1
+SRR9130495.47,D00236:723:HG32CBCX2:1:1108:14223:1987/1,GCTTTCCTGGGAGTGAGCTCCCTGGCGGCCGCGGGGAGCTCAGGGCAGGCTCAGGCATCTCCAAGGCGGCCCTGGAGGTGATAAAACTTGAGAAATAACTA,CCCFF?DDHFBHGHGGIIGGIGIEGFGIGEIIIIFBDBD?CCDDBDDDBDDDCC?CDCDDDDDDDDD@BBDBBBD<AB8ACCCCCDD>>ACC?CCDDCCD@
+SRR9130495.48,D00236:723:HG32CBCX2:1:1108:15049:1993/1,TGACCAAGAACTCACAGAGATCCCCCCCCCCAGGGCTAAGATTAAAGGCATGTGCCACTGCCACTGGATAGATATTATCTTTTATTTTACCTGACTGGTTG,@CCFFDDDHDFHGJJJJIJGIHHHIIJJIJFE=(5;?@>@A@;@C>CAB=@<:@C@CA:>CC3:>CB<@@?344>>@@A>CDC>ACDD:>4>>>ACD?CC(
+SRR9130495.49,D00236:723:HG32CBCX2:1:1108:15487:1951/1,ACGGAGGGTGGGGCTGGGTGATTGTGGTTGTCTCCTTCTTCACCCAGTTCCTCTCTTACGGATCCCCGTTAGCTNTNGGGGTCTTGTATGTAGAATGGCTG,BCCFD@DFDFHHGDGIIICGHIIJJIJGHIIJIIJJJIJIJIJEHIGHHHHHHHFFFFFFDDCDDCD@DDDDD:#+#+2<@8<CDCCDEDDBCCDCCDDCB
+SRR9130495.50,D00236:723:HG32CBCX2:1:1108:15659:1969/1,AAGTGCAGCACATGTGAAAAGTCCTTCAGCCACAAGACCAACCTGAAGTCTCATGAGATGATTCACACAGGAGAAATGCCTTATGTCTGTTCCCTATGTAG,?;=BDDDEDDFFFIIIIIIIIIGGHIHHBHHIIGEGIGGEHGIII@HDHI>GHIIIEHGACFHIIGGIBHIIHHC??BDC@BBCECDCE63>@@CACCDD@
+SRR9130495.51,D00236:723:HG32CBCX2:1:1108:15923:1957/1,CCGCAACTGCCATGGAGCCACAGCCTGGTCCGTAATAGATGCAAAGCTTCTCAATAGTCAGGGGCGTGGTTTCGCGCAGCTTGGAGGCCAGCAACAGGCAG,CCCFFFFFHFHHHIIFIIIGIIFIIGJIIJJIFHGHIIIIIJIIFIJIIIJJJJJJJGGIGJFFH@?BBBDBCDDDDDDDDDDDDDDDDDDDDDDDDDDD?
+SRR9130495.52,D00236:723:HG32CBCX2:1:1108:15793:1968/1,GTTTTTCCACAGACCTCTGATCTCTTACATTCGAAAGTTCTACTACTATGATCCTCAGGAAGAGGTGTACCTGTCCCTAAAGGAAGCGCAGCTCATTTCCA,BB@FFFFFFFHGDGFHJJJJIFIIGGG@FIIIGIBGGDHIIIJCHIIJJDHIIJJJIIIGIIJJFHHIJCHGDHIIHHHHHFFFFFDDDDDDCDDDDEDDE
+SRR9130495.53,D00236:723:HG32CBCX2:1:1108:16082:1968/1,GAAACTTGTTTGTGACGTGTGTATTCAACTAACAGAGTTGAACCTTTCTTTTTACAGAGCAGCTTTGAAACACGCTTTTTGTAGAATCAGATCGGAAGAGC,@<@ADDDECBFFHIFEGDG;EEHHB@<CHHHGHCFII9CDCG@@DGHGH>FHGHIIGGEHGGHGGEGEGICGCEFFDB@D>AE<A@>>ADC@CBB<B@??A
+SRR9130495.54,D00236:723:HG32CBCX2:1:1108:16094:1977/1,AGACAGTTTGAAAGAAATAATTGATGTGATAAGCTTGGAGTTAGTAGTGGATGCAAGCTGTCAGTTCAAGTAATCTCTCTATTACTGAAGGTTCCCATCAT,@C@BFFFFHHFHDDEFGEHGIGH>FGIIJJJJIHHIJJGH?DGGHCFHHIJJEEIIJAHIJJFG=FGGGIFHHIIDHGEHIHHHHGHGEB;?CDCECEEDD
+SRR9130495.55,D00236:723:HG32CBCX2:1:1108:16048:2000/1,AGGACAGGAAGGACGCTTTGAGATATGATTTCACAGGCGACAGTGAGAGAAAACCAATGTCTTTAATGCATTTCTCTGCAGCATGTGACAAACTTTCAACA,CCCFFFFDFHGHHIIJJJJIFGGIJJIIIIJIJIHJIIJIHGIJJIJGGIIJIJJHHHHEDCDFFFEEEDDEDEEDDDDDDDDDDCDEDDCDDDDDDCCD@
+SRR9130495.56,D00236:723:HG32CBCX2:1:1108:16580:1970/1,GCCTGTACTCCCAGCTACTTGGGAGGCTGAGACAGGAGAATCACTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGACCGGGCTATTGCACTAGATCG,@@@FFD?DBFFHHIIEHCIJIFIJHEDCH@GGEBFHHIJJIIIIIJJJJJIFHFHF@G-6@AAEDFFF>AEC@@A?;=?BCD6/<@>BAAC>:@C:CDDA?
+SRR9130495.57,D00236:723:HG32CBCX2:1:1108:16594:1971/1,TCCTCTGACTTTGACACTAGTGTTGACCTTGCATGAGGAGATGTTCTCCATTTGGACTAACCTGATGTACACAGACGTTACACTTATCACAGAATACCATA,CCCFFDDFFHFHFHIJIJJIHIIIJJJJJIJJJJIIIIHIGIIJJJIGIIJJIIJEHIIJIJJJIGIJJJEIHJJIIHHEFFFFFFCCEEEEDCDDDDDDC
+SRR9130495.58,D00236:723:HG32CBCX2:1:1108:16808:1998/1,ACCAATTTTCCCCTCCCCTTCCTCCCTCCCTCCCAGCCCCCTTCCTCTCTCTACCTCCTGTTATTGTTTTGTTCCTTGTTCTATGTAGGATTGAAGCATCT,@@@FFDDFHDFHGIJJJJIIGGDFHI>DGC;DHI9??FHIJIIHG<C=8B;=CFE@EGEE@A=?EHHFFF<BAA@@AECDA>>>3>;ACCCC9:@>@:>AA
+SRR9130495.59,D00236:723:HG32CBCX2:1:1108:17428:1967/1,TGCATGGTGCTGAAAGCTTTGTTGCAGCTTTTCTTGGGATTGCTTAGCTGCTCCGGGTCGATCCACTTGCAGATGAGCTCTTGCTTGATGCACTGCTGCCG,?<<??BDDD4:<D<DE+<C<CFEE<<+2A<?E*@E9*)?DD)::*:?4B*BDDDDIAD/@A(6??DA@;3?;;6(((.-(55(;35:9>A3>A>>AAAA?3
+SRR9130495.60,D00236:723:HG32CBCX2:1:1108:17508:1988/1,TTGTTCAGAAAAAAGTATCTTGAAACCAAAAGAACTGGGATCTTGTTAAATGCAGATTCTGTTCATTAGGTATAGGTATGCAGTCTTACAAAATGAGGTAG,CCCFFEFFHHHHHJJJJJJJJJJJJJJJJJGIJJJJJJJIIJJJJJJJJIJJIJJJJJJJJJJJIJJIIIEHHBHGHHEFFFFFEEEEDEEDDCDCDDCDC
+SRR9130495.61,D00236:723:HG32CBCX2:1:1108:18425:1951/1,CCACTTAATAAATCACCTATCAAGTTGAATTATTTGTGCAAAGGCACTAGGCTGAATAGAGACCACTCAGTAGCNTNTTTTTAATCTTGCTAAGAAAGAAT,CCCFFDDFHFHHGJIIJJJJJJHGHEHHHIIJIJJIJGJIHIJHEFDHGHIFIJJGHIJJJFIGGIHIIIJIII#-#-5@DFFEEEDEEEDEDDACDCCBC
+SRR9130495.62,D00236:723:HG32CBCX2:1:1108:18468:1964/1,CTATTGACTTTTATTAGAAAGGGTCTTGTTGCATAGGTAGGTCTTTAACAACCATCTCTTAAAGGGCTGGGATTGCCAGAGTAGGCCAACACGCCCAGCTA,CCCFFFFFGGHHGIGIJIJJIIIJJJJIJJIJJJJIIJDGEHGIIJJJIJJJHIJJIGFHGIJGEGIJJJIIHHHHHHFFFFFEDEEDDDDDDDBDDBBD@
+SRR9130495.63,D00236:723:HG32CBCX2:1:1108:18615:1941/1,NAGCCGAGAGGCGCCGGCTCACCTGCCTGGGTCCCGGCCTTTCTCCTGCAGTGCCAGGGATTCACCTGANGNCNNNNNNTCTNCTAGGCAAGCNNATNCTT,#1:DDFDDHHHHHIIJIIFGJJIEFHHIHHIIIJJIEHFFEEEEEEE<CDCDDCCCDBDDCDDDDDDDC#+#+######++8#+8??<CDDBD##+2#+2<
+SRR9130495.64,D00236:723:HG32CBCX2:1:1108:18957:1948/1,ATAATGAAGAAATTTTGGACCTTCTATGTTCATCTCGTGAGAAAGCTACTCAAATAAATATCCGGGAGGACCCTNANGAAGGCATAAAGGTGTGTTTTCCC,"CCCFFFDAHFFGHJIIJBBGGIJJIJIIJIJJJIF@GGGHIIJGEEGHI@GIGGIEIIIIJGJIIJHEEHFEBC#,#,5?BDDDDDDDDCCCCDACCDDCC"
+SRR9130495.65,D00236:723:HG32CBCX2:1:1108:18983:1999/1,CATCATCCTGAGTAAGGTAACCCAATCACAAAAGAACTCACATGATATCTACTCACTGATAAGTGGATATTAGCCCAGAAACTTAGAATACCCAAGGTACA,CCCFFFFFHHHHHIJJJHFIJJJJJJIJJIGJJJHIIIJJIJJIIJJJJJJJJJJJJJJJJIJIJJIJJJJIJJJJJHHHHFFFFDFEEEEEE@ADBDDDD
+SRR9130495.66,D00236:723:HG32CBCX2:1:1108:19168:1981/1,TAACCGGTGAAGTGTCAAAGAGGCAGGAGTGGAGGGCTGCGGGGGTGACAGGGTGTGGTCTGCCTGGAGCGGCGACGTGGGAGAGCGGGACAGAGGCCTGG,CCCFFDFDHHHHHIJJJJJIIJJJJJIGEHGHHIJIJIJJJIIDDDDDDDDDDDDDDDCDDDCCDDDDDDDDDDDDD@BBDDDDDDDDDDDDDDDDDDDDD
+SRR9130495.67,D00236:723:HG32CBCX2:1:1108:19555:1966/1,ATCACATCTCCATTCAATTCACCTATTTGCCCTGTGCAGAAGACAGACAGATCTTGGAGAATGATAGTGGATTATTATAAGCTTAGCTAAGTGGTGACTCC,CC@FFEFFHHFFHIIIJJJIJIJIIJIJIIIJIGHGEGGGIIFGIJGIJIIIIIJJFHIJIJJIIJICGGIJJJJIJJIHHGGHFFFFFFBAECECACDDA
+SRR9130495.68,D00236:723:HG32CBCX2:1:1108:19764:1940/1,NCAATTTTGGAAAAGTGAGTGAATTAAAATTCCAGGAAGAAGTTTAGCAAAATTGTAGANCGGAAGAGCNCNCNNNNNNANNNNANNNACCACNNCNNATC,"#1=DDDFFGGHHHJJGFGIJJIIJIJJJIJJIJIIJJIJIIGGGIJJJIIIIHHGIFHI#-<CHGIJJJ#-#-######,####,###,,8?B##+##+++"
+SRR9130495.69,D00236:723:HG32CBCX2:1:1108:19805:1986/1,CGCAGTGCCCCGTCCTGATTGATCGCATCGCTGGGCTCAGATGACTGTAAAATGAATAGATGAAATCCTTGCTTCTGGAAGATTTTCTTGGGCATCTCCGG,CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJIJJJHIIHHIIIJJJJJJJJIGGGHIJHHEHHGHFFFFFFEEEEEEDDDCDDDEDDDCDDDDDDDDDD
+SRR9130495.70,D00236:723:HG32CBCX2:1:1108:20271:1962/1,TGATGATTCCATTCCATTCCATTCAATGATTCCATTCGATTCCGTTTGATGATGATTTCATTCGAGTCCATTTGATGATTCCATTTGATTCCATTCGATGA,@<<ADDDDDFHFFFFHEFHEGIIJIICHEGIJJCHHCBBHHJJIHECG@GHIIICIJJEGIGGEGIIIGHIIIIGHFCHHGDFGEGIIEEHIGHIDGGIGF
+SRR9130495.71,D00236:723:HG32CBCX2:1:1108:21157:1952/1,CCCAGCACCAAGCGTCCATCTGACTGCTCATCGGCGGTCTAGGGAGTAAGCCGTCTGGAGTTCTCTAACCTGATNCNGTTTCCACTTCCACAGGTGACAGA,@@@DDD?>?DFF<GF;CA?FHDHAH?:E<DF4D@@DF-''=@CAFA?;;B77=@B?B@B<55>;5:AAB9>29(#+#++8++4>>:@>AA:@1<@@A(:4?
+SRR9130495.72,D00236:723:HG32CBCX2:1:1108:1440:2047/1,GCTGGTGCAGGACACCAGAATCCGCTCGATCATGCTCCCTAGAGAGGAGGGGCACAGTGAGTACACATAAGCACATGTACACACACACCCAGGACCCAAAG,CCCFFFDEHHGHHHIIIIIIIIJJIJJJGEGHIJIJJJJIIJGHIIJJJIDFEDFFFFEEEEDEDDDDDDDDDDDDDEEEEDDDDDDDDDDDDDDDDDDDA
+SRR9130495.73,D00236:723:HG32CBCX2:1:1108:1468:2080/1,ACTGTCTTTTTTTTAAAACAGGTGATTGCCCGTTGATTGTTCAGTTTGCTGCTAATGATGCAAGACTTTTATCTGATGCTGCCCTGCTAGTCTGTCCCTAT,CCCFFDDEHFFDHIEIIJHGCGFHCIIHIIIHH@FGGIHIGHIJJIJGIIIJBHIGEIHGHHGGHFFFFFFEEEEDEDDDDDDDDDDDCDDDEDDDDDDDD
+SRR9130495.74,D00236:723:HG32CBCX2:1:1108:1333:2084/1,ATGAGCACACAAGGGATGATCAGATTGATGGTGTAGAAGAGTGGCTTGCGCTTGATGATGAAGTCATAGGTCACGTCCACATAGCTGGGGTCCTGTGGGTT,CCCFFFFFHHHHHJIJHDIIHHHIIJIIJJJJJIJJIIJIJJJIBDGIJJJJIJJJJGIIIJIAHEEHEFFFFF>EDCDDDDDCDDCDDDDDDDDDCDDDD
+SRR9130495.75,D00236:723:HG32CBCX2:1:1108:1447:2137/1,TCCACTTGTACAAAAAATTACAAAAATTAGCTGGGCATGGTGGCACACACCTGTAGTCCCAGCTACTCGGGAGGCTGAAGTGGCAGGATCACTTGAGGCAG,CCCFFEFFHFHGHJJJJIJJJJIIDIEHJIIJJJIGJJJHGJIIDHIDGIJIJJIGHIJJJJJHHHFEEBDCDBBDDDDDDDDDDDDDDDDDDDDDCDDD@
+SRR9130495.76,D00236:723:HG32CBCX2:1:1108:1499:2151/1,GAGAAAAAGCATCCCTTTAATAAGGCCGCCCCGGTTCCAAATCAATCCTGGCATTGCAGGAGGCAAGGGGGAAACACAGCCACGAAATTGGATTAGCTCTT,CCCFFFFFGGHHHJIIJHIEIJJIIIIJIIGJJIHJIJJIGIJJJIIJJHHHHHFFFFFFDCDBDDDDDDDDDDDCDDDBDBDDBBDDDDDCDDDDCDDCD
+SRR9130495.77,D00236:723:HG32CBCX2:1:1108:1280:2166/1,GCCTTCTTCCCAGCAGCAATATGGCTCTTTCTTCAGCTCTTATCAGTCACATCCATCAACGAGTGGCTTTTAAAAGGGTATGTTTAAACCTTTTGACGGGA,CCCFFDEFHHHGGJIJJIJIJEIJJJJJIFGIIIIIIIJIIGIJJGIIBHIJJJJIJIEH>CG;CHCHGHICHFFFFFFDDC;@CCEEDDCDDCCDDDDDB
+SRR9130495.78,D00236:723:HG32CBCX2:1:1108:1458:2216/1,TTTCTTTCCACACATCCCACCTAACACCCAAACTAAGCACTCAGTGCTTGGAATCTCCCCACCCATTCCCTCACCCCTGCTCTTCCATCATTTCCTCCAGC,CCCFFFFFHHHHHIDHIIJJJJHIIJFHIJIJIGIJHGIIIIGJEHIGIIJCGEEHJJJJJJJDHEHHGFFFFFDCDDDDDDDDDDDECCDDEEEDDDDDD
+SRR9130495.79,D00236:723:HG32CBCX2:1:1108:1634:2001/1,TGTGCATTTCTCATTTTTCACGATTTTCAGTGATTTCGTCATTTTTCAAGTCGTCAAGTGGATGTTTATGATTTTCCATGATTTTCAGTTTTCTTGCCATA,CCCFFFFFHHHHGJJJJJJJJIJHGIJJJJIIIIJJIGIIJJJIJJJIIFIIJJJJJIJJJIJIIIIIIJIJGJJJJFHHGGHGFFFFCEFFDEEDEEDDD
+SRR9130495.80,D00236:723:HG32CBCX2:1:1108:1566:2120/1,GGACGAAGTAAGGGAGGAGCAACTGACAACATTCATCTTGTCTGTCTCCTCCACGTCCCGAGGTACAAGGCGGATGTCATTCTTACTAATTTTTTTCTTCT,CCCFFFFFHHHHHIIJJJJIJJJIJJJJJJJIFIJJJIJIJIJIIJJIJIJJJJIJJIIJHHFFEEEEEDDDDDDDCDEDEDEEDDDEDDEECDDDDDDDD
+SRR9130495.81,D00236:723:HG32CBCX2:1:1108:1863:2047/1,AAATTCGGACCCCTTGGGTGGAATATTCCTTACGAATTCAATGAGACAGATCTAAGAATCAGTGTGCAGCAACTCCACATGTTCCTGGACCAGTATGAGGT,@BCFFFFFHHFHHHIJIJGIIIJIJJJJIIJJIIIIJJJJGIJJJIJJIEGIIGIJIJJJEGHHHGEEHFFFFDEEEDDDDEEEDDDDDDDBBCDDCCCCC
+SRR9130495.82,D00236:723:HG32CBCX2:1:1108:1844:2145/1,TAACTCTCTGCCTGCGATGTCCCTACCTTCCAGAATGGTGCCATGACAACGGTGTCAACTACAAGATCGGAGAGAAGTGGGATCGGCAGGGAGAAAATGGC,@CCFFFFFHHGHHJJJJJJJIJJJJJIJIIIHIIIJIIJJJJIJIIJIJJJJJJJJJIJJIIJEHHGHHFDFDDDDDCDCDDDDDDDDDDD?>BDDDDDDD
+SRR9130495.83,D00236:723:HG32CBCX2:1:1108:1772:2188/1,GAGGTAGGGGTGTGTGTGAATGGGTGAGTGTGTGCCTATGCTTGTATGCCATATGAGAGAAAATGCAGCATTTAAAATCAGTGGTTAACGGCCAGCACAGT,B@BFDFDDHHDDHHGIGIJIJGIJ:CFHHIGGIJJIEHGIIIJIIIFHGIJBHIJJJJJJCHHIHHHHHGFDFFFFEEEECEEDDDDDDDDDDBDDDDDCA
+SRR9130495.84,D00236:723:HG32CBCX2:1:1108:2103:2085/1,TACAAATGTGCCAGGCACTCTTCTAAGTCCTCACATGCATGAAGTTATACAACTCTACAACAAACCTAGGAATATAAACTGAGGGCAGGGACCCCCAGCAA,CCCFFFFFHHHHHJIJIJJJJJJJJJJJJIJJJJJJIJJJIJJJFHIJJJJIIJJJJJIJIIHIICHHIJJJIIIJJHHHFHHFDDDDDBDDDDDBDDDDD
+SRR9130495.85,D00236:723:HG32CBCX2:1:1108:2067:2091/1,ACCAGCCCTGCTGCCACCCAGCCCACGTCCCGCGCGCCACCCATGCTGCTGCCTCGGAGCTGCAGGGAGCCGGGGAGCCAGGGCCACACGCAGGTGCAGCT,?@@D?A:BF8DDFFFFFFFFAECBF@GFECAEFIIIIIIFBE?DBBD;@CCCCBBBBBB@B::AABBBBBB7>BBB>@BB?B>B<BBBB@BBBBBBBBA@B
+SRR9130495.86,D00236:723:HG32CBCX2:1:1108:2104:2209/1,GGTTGTGAATACTGCAGTCTTTGCCTGTCCAGTCTGGCTGACAGATACACTTCCCCTCGTTGCTGCAAACCTACAGGTAGGCGAGGCCAGCATGGATAAGC,@<@DDDFDHDHDFGHEGHIGGGIIHIIBGHHIHIIIIDGGGFEHIIIIIIIIIIIIGGGGFHGEAEDHIHG@EHFFF@C@1>>BB?/?A?BCCCBDDDD>@
+SRR9130495.87,D00236:723:HG32CBCX2:1:1108:2387:2038/1,GGCTAACCACTGCCTTGTCAAGTTGTGTAGAGTGAGATTCAGGGGTGTTGAAGTAATGTCCTTGTTACTTGCTGTAGGGCATCTGTTTTCTGTGTATCCCA,CCCFFDDDDHGHGJEIGHHIJIHGGIIHGIIIIIEGBEHGGHIGGAFHIJJJJJJJJIDGHIIGIJJJIIHGFHEHFDFEDCEECDCDDACCCAACDFCCC
+SRR9130495.88,D00236:723:HG32CBCX2:1:1108:2285:2075/1,CTGAAAGCTGAGCGTGAGCGTGGTATCACTATTGACATCTCCCTGTGGAAATTCGAGACCAGCAAATACTATGTGACCATCATTGATGCCCCAGGACACAG,?;@DDBDDDFFD>ACGED@D8@):E*::??FFC@<BDGE99?F?B?F;?CCBF>;FEF>E;CC=CC=@DDD>?;>A>A>A;AB3;A(;@:??<?89<???2
+SRR9130495.89,D00236:723:HG32CBCX2:1:1108:2395:2081/1,CAGACCAAGGAGAGCAAATGCTTAAGGTACCAATACCTGGTTAATTCCAAAACAATACTTACTTTAGGGTCCGAGCTCTTGAACTTTAACCTTTCCACCAA,CCCFFFFFGGHFHJEIIJJJJJJIJJIJJJJJJIJJJJHIIIJJJJIJJJJJJJIJJJJJJJIJJJJJJJJIGGFFDEDCEEDDDDDDDDDDDDDDDDDDB
+SRR9130495.90,D00236:723:HG32CBCX2:1:1108:2350:2145/1,GGAGCTCATGGAGGAAGAACTGTATGTATCTCTGGGGAATGTACTTCCTACAGCTGACATTGCCCAGTTTAAGCAGGTGTCAAGTCTGTGGCTGGCAAGAT,CCCFFFFFHHHHHIJHIGIIJIHHIJJHIJIFIJJJJGGIJHGIFJIGIHIIJJIJIJHIFHGGFIJJIJJJHJGGHHHFEFFFFEDDEEEDDBDDDD?CC
+SRR9130495.91,D00236:723:HG32CBCX2:1:1108:2261:2146/1,GACGATGATCTTGACTTCCCTCTGCCCGACATCCGATTAGAAGAGGGGGCCATGGAAGATGAAGAGCTGACCAACCTGAACTGGCTGCATGAGAGCAAGAA,CCCFFFFFHHHGHIIJI?FHHHGJJJJJGIIJJJJIJIHHHIJJIFGIIHFDFFEEEEACDDDDDBDDDDDDDDDDDDCCDDCDD@BDDDDDDDDDDDDDD
+SRR9130495.92,D00236:723:HG32CBCX2:1:1108:2270:2221/1,GTTACATCATCATCATCTATCTATTGAGCCTTAACTCCCTACTCAGAGAAGAGATTTTAGTCCATATCCGGCAGCCCGAGGGTACAGCGCTGAACCACTTC,<;?BD?>DFBCB4<<AEAEHE@FHB9FCGHBHG?HE9E3?CDHD<C3B@BDEII<9?:?FBFAGB:<C=@8@;:C;(59<@B8>CCD@=BB@-(4812>>>
+SRR9130495.93,D00236:723:HG32CBCX2:1:1108:2748:2098/1,CATCATCTTTTTTTTTTTTTTCTCCTGAAAACTGTCTAGTAGTTTGATATATTTTGTCCGAGGTTATTTCAAGTGTTTTTTTTTTTTTTTTTAAAACGGTG,@@@DDDDDHHHHHIIFEHIIH8))7)7CEF9).)7;;>B@>9BD;;(6(55>DDDCBCC@/8-084@CC>C(((+4>?CBBBBBBBBBBB>&23:A(5?((
+SRR9130495.94,D00236:723:HG32CBCX2:1:1108:2733:2156/1,GACTGAGAAGAACAGAAAGGGAGAGAGAGGCCAATGGAAATACATGAGAAGGGAGAGAGGGAGAGAGAGGGAGGGAGGGAGGGAAGGAGGGGGAGAGGGAG,CCCFFFEFGHHHHJJGIIIJJHIIHHIIJJJJJIJIIHGJJJGIJJJJJJJJJHGGHHIHHHFDFCDCDDD>BDDBDDDDDDD>BDD?BDDDDBDBDBD<B
+SRR9130495.95,D00236:723:HG32CBCX2:1:1108:2665:2186/1,AAGGAAGAAACTCTGGATACATCTGAACATCTGAAGGAACAAACTCCAGACACGCCATCTTTAAGAACTGTAACACTCAGATCGGAAGAGCACACGTCTGA,@@@DADA?DAFHHHIJBHGIIEHJIFJJIJJIJIJJIIIJJJIGIIGIJJJGIIGIIJJJIGJIIIJIJHHHHHHFEFFDFE3;>@D?ABD@BD?BBDDDC
+SRR9130495.96,D00236:723:HG32CBCX2:1:1108:2818:2076/1,ACACTTCATGGCAACCTGGCTTAGATTCTTCAAAATTTCTGATCCTATACCAAAGCCTCTGTAATCACTCATCACGAAGAAGTCTTCAAGATACAGTAACT,CCCFFFDDHGHHHJJJJIIJIIHIJHGCHIFEGGJJJJIJIGIIJJJIIJCEHIIIIJIBGHGGIIJIIBFGGGGHHGHFFFFDEEDECEDDDDCD>CCDE
+SRR9130495.97,D00236:723:HG32CBCX2:1:1108:2848:2112/1,AACCTCTTCTCTTTGTCTTTCTCTTTATCCTTCTCCCTCTTGCCAGGACTGGACTCGCTGGTGATGGTGACGACGCTGGTGGGTAAGGTCTGCGCCCGACT,@@BFFFFEHGHHGIJDEHIJIIIIIIJIFHIIIJEIDHIIIIJJIIIGIEIIJJIIIJFEHFHIIIGIIJIFBEDDBD>=?BB@CACCCAACDDBDBB5<B
+SRR9130495.98,D00236:723:HG32CBCX2:1:1108:2918:2118/1,CCACATCCCCAACCCTGAGCCTTCCCACTCCATCATCTCTAGATCCAGTGGTGCCTGGTGAGGAACAACCACTCCCAGACATGCCCTCAGGAGCAAGCCTT,?@@BDDBDHHDBFDAEGBECFIBGHEH@G@CGFGHGGIEEHGAGGCHAFGGFEGGGHIIIGHHIIDEEE?7?C>;6@;ACBCCCC?@AA>C>?<<<9<?CC
+SRR9130495.99,D00236:723:HG32CBCX2:1:1108:3133:2096/1,GGCACTTGGCAGTAATGTGACACACACAATAGAGCACAATCAACAGGAGAGCCATAGGAGAAGCCCCCTTACCCGGCCCCTTTACCTAGGAACATGGCCAT,@C@DBBDBFHHFHIFCGIG<@9FDEHGGHGEGGIBHGD)?BF>)?FHFCAG=GFFG>FGGEGHIEEBEDEFC>C@::=BB@BCACCC@CA3:(8@C<8?CC
+SRR9130495.100,D00236:723:HG32CBCX2:1:1108:3014:2117/1,CCCTCCTGAAAAGGTCCAGCTCCAAAGCCTGACCCGTAGCTGCAGAGAAGAAAGCTTTTCCTCTAAAGGCTGAGGAAAAGATGAAAAATCACTGCTAGAAC,CCCFFFFFHHHHGIJIJJJJJJJJJJJJJJJIJJJIJJIJJJJIJGIDHHIIIJJIJJJJJIJJJHHHHHFFFFDEEEEDDDDDDDDDDDDDDDDDDDDDD
+SRR9130495.101,D00236:723:HG32CBCX2:1:1108:3316:2011/1,GCAGAGCTGAATGGGCAAGCCCAGGACCCTTTTCAGACATTCTGCTGGCCTTTGGAAAGTGTACTCCTGTTGTATTTGATTACTTTTAGAGGACAGTACAT,CCCFFDDFHHHGHJJJJIJFGIGHJGIJIIIIIHIIGIIJIIIIJJJIIIIJIIIGIJGIJJJJIIJJJEEEE?ECFFFFFFCCEDEEEDDDDDDDDEDCD
+SRR9130495.102,D00236:723:HG32CBCX2:1:1108:3264:2036/1,GGGTGCTGGAGATAGCCCACGTACACTCCTTCTTGCTGGGGTACTTGTCAGGCCAGTTGGGGCTGGTGATGGTGCCACTGGTGGATGTCACCTTGTGTTCA,"=@<=B+AD>BFDFIIDEDGEIGFIIIIIICDFGFFGIII;D?F>?*/9BF>DAF;CFFGI>/:=?>7@BAA:;@5=A5>@=,98?:>@(;:4>ABAB?ABD"
+SRR9130495.103,D00236:723:HG32CBCX2:1:1108:3400:2065/1,TCTGTCTGTCACCAGGTTGGAGTGCAGTGGTAGGATCATGGCTCACTGCAGCCTCGTCCTCTTGGGTTCAAGCAATCCTCCTGCCTCAGCCTCCCAGGTAG,@@BDFFFFHHHGHIJJFHEG@GHHIIAFD@HGGGEHIJJJGIJJGGGIHFDAHHHHJFCGGGHGJI;CHFCEDDFFFCEDEEDDDDDDDD<<ABBCCDD>C
+SRR9130495.104,D00236:723:HG32CBCX2:1:1108:3468:2219/1,TGCACTTCGTTCTCTTAATGAAACCCTTTGACTTAACCATGACTCCGCTCTGCTCTTGAGTTTGCAAGTGTGTGCGAGTGCCCGAGAGACAGTTTTTTTTT,CCCFFEFFHHHHHJIJIIJJIIJJJIIJJIHIHJJJJJFHFHIIJIJJJJIJIJJJJJGGIIJJJGDIJJJIHHHGFFDDEEEDDDDDDDCCDCEDDDDDD
+SRR9130495.105,D00236:723:HG32CBCX2:1:1108:3722:2006/1,TCCATAGTTTCGCAGAAGACTTGGAAGGATGTTGATGTATATGCAGGTCCATTATCAGTTTTTAAATTAGATGGTTTTCCCCAAGCTGCCCATGCGTCTAA,CCCFFFDDHHHHHJJIJJIIHGHIGIIDFHHIIIHHIJJIJJIJIJJJJJJIIJJIJG=DHHJJIJIIIJJJJJIGHGHHFFBFDDEEEDDDDDDBBDDDD
+SRR9130495.106,D00236:723:HG32CBCX2:1:1108:3517:2148/1,CTCTGTTCTGTTCCATTGATCTATATCTCTGTTTTGGTACCAGTACCATGCTGTTTTGGTTACTGTAGCCTTGTAGTATAGTTTGAAGTCAGGTAACGTGA,CCCFFEBFHHHHFGGGIEEHIIJIJJIJJIIJIJJHIIJIIJJIIFHGIIIIJJJJJJFIJIJJJJGIIJIJCHIJIJHGJIJHHHHHHFFFFFFEEDECA
+SRR9130495.107,D00236:723:HG32CBCX2:1:1108:3927:2234/1,CTGTGCTCTATGTACACGCCCATCTGTTTGCCTGACTACCACAAGCCGCTACCACCGTGCCGTTCCGTGTGCGAGCGCGCCAAGGCCGGCTGCTCGCCGCT,@C@FFFFFHHHHHJJJJGIIJIJJIJEHIIGHGJJIJJJJJJIIGHHIJIJIGHJIIJIHHGFFDEDE?BBDDBDCDDDBDDDDBDD>BDBDDDDBDDDB<
+SRR9130495.108,D00236:723:HG32CBCX2:1:1108:4124:2011/1,GACTCAGAGCCAGGGCCCGGGAACAGAGATGACTCGAAGGCTAGGGCTCCAGCCAGACTTACCGGCACACGTACACCTCTAGGGGTGGCAGGGTGCTGGGT,CCCFFDDEGGGHHIJIIIJIIIIJIHHJJIJIIJIJIGGIIGIIHIGGIGHBHGHFEFFEECEDDDDDDDDBDDDDDCBACCDDDDDDBDDDDDDDDCD?9
+SRR9130495.109,D00236:723:HG32CBCX2:1:1108:4130:2090/1,TTCTATTTCTATAAACTGGCCTATTTTGGGTATTTCATATATATGGAAATATATAATTTGATTTTTTTGTTCTCTTAGCTGTATGTTTTCAGGATTCTTTC,@BBFDFFFHHGHHIJJJJJJJIIIJJJJIJJJIJJJJIJJIIIJJJIJJJJIJIIJJJJJJJJJIHJIJJHHHHHHFFFFFFEEEDECEEDDDDDCDDEDD
+SRR9130495.110,D00236:723:HG32CBCX2:1:1108:4176:2091/1,AAATTGAAAGTAAATGTATACTGTAGTCCCACGCACGAGTGAATAAAGGGGTGTCTAAAAGGAGTGTGTTCTCTTCCAGGCTGCATCTCTCGGTACTCAGC,;8;ABD?+AA=ADBHIGBHE?A<IHGA<ECFGHABFG?DGEFGHIIG@3DBF<;CAC@AHFFFHEEE@DCCACCACCCCCBBBBCC@CCDCB???>CCCCC
+SRR9130495.111,D00236:723:HG32CBCX2:1:1108:4108:2121/1,ATGCGGAAGTAGGCAAAAATGATGTGCTAGACTACAAGAATTCCTTTTACAGAAAGTAACAAATACAGAGCCAAGAAAGTTTTTGTTAATTATCACGGTGT,@@@ADADA@AD>FIIBBBFGIBGHJDCIGEGGGHHHIJIIJJJJGHIIEHHEGHJIHGGGIFAGGGGIIG>=CHHFD?@;CCEDDDDCDD>>ACDCB@8<5
+SRR9130495.112,D00236:723:HG32CBCX2:1:1108:4384:2110/1,ACACAGGCAGCAATGATGTCTTTACTTCTTTATTTTTTTCGACTTCATCTACAGAGCTTAGCACAGCCATTGGAACAAAATTGGAGCTCAGTGCACAGTTA,@@@FDEFDDFF3CCF?FHCH@DEEGEFHIIFGBGGGDGIHAFBGDDHHIB<CCH>AGGDGHE@CHAHBFFFF<CCEDDDDAC@CADCDAC?AACCCCA4:A
+SRR9130495.113,D00236:723:HG32CBCX2:1:1108:4449:2134/1,CTAGCTGGGAGTGGTTAATCCCAGATCTCTGGACACAGGGGTAGATGGAACAACTCAGTGAGTTCCAGACCAATCTGGACTACATAGCAAGTTCTAGGCCA,B@CFDDDDHHHHHJJIIJJJJIJIFGIJJJIJJIIJIIJJJJJIJIIIIGIJGHIIFFHIJIIJIIHHEFHFFFFFEEEEEEDDDFDCDDDDCDEEDCDDD
+SRR9130495.114,D00236:723:HG32CBCX2:1:1108:4398:2225/1,GCTGAATAACCAACTGACTATGTTTCAGAAAATCAACCACTTCCCTGGCATGACGGAAATCTGCCGCAAAGATCTGCTGGCTCGGAACCTCAACCGCATGC,CCCFFDFEHHHGGJIIGGIIJJHIJJJGGGHIJJJIIIIJJJIJJJJIJGIJJIIGDIIIJJJJJJHHFFFEEDEDEDDDDDDDDDDDDCDDCDDDD>BDD
+SRR9130495.115,D00236:723:HG32CBCX2:1:1108:4445:2247/1,TCTGTATTCTGTGTCATCTGCCATTCCTTGACTCCCTGCGCCCTTCAGCCCACAGGAAACGTGTGGATGACACACGAGGAGATGGAGTCTCTGACGGCAGC,CCCFFDDDHHHHGJJJJIJJJJBHHJJIIGIIJJJIIGIFIJJIIIIGIJJIIIJIJCHIIJJJIHHFHEFFFFDDDDDBDDCDDCDCDDDDCCCDBBDDB
+SRR9130495.116,D00236:723:HG32CBCX2:1:1108:4698:2005/1,GAGGGAAGGAGGGAGGGAAAGAAGAAGGGAGAGAGGGAGGAAGGCAGGACTGTCGATGCAAGTACCTCGCTTCCTTGTTCTTAACTCATTTGATTCTTGCT,C@BFFFFFGHHGHIIIJJIBGGDHC@FEGDHIIIHGEHHEGCGIHHHFFFFDEEDDDEDDDDCDCCCDDDDDDDDDDDDDEDCCCDDDCDDDED:CCDDDD
+SRR9130495.117,D00236:723:HG32CBCX2:1:1108:4588:2182/1,CTGGGGTGCAGTGGTGCAATCATAGCTCACTGCAGCCTCAATTTCCTAGGCTTAAGCATTTCTTCCACCTCAACTTCCCAAGTAGCCAGGATTACAAGCAC,CCCFFADDFFHHGGHHGIIJIJJJJJJHIIJIJJIFIJJEIIJIJIGIJIJJJJJJIJJJIIHIIJHIIFFHGHHFFFFFEDEECCCCBDBDDDDDDCDBC
+SRR9130495.118,D00236:723:HG32CBCX2:1:1108:4964:2029/1,CCCCGTCTCTACTGAAACACACACACACACACACACACACACACACACACAATTAGCCAGGCGTGGCAGCGTCTGCCTGTAGTCCCAGCTACTCAGGAGGC,;8=:DDDDFFFAFIIFFBEIIEFIFIFIEFFFIIBEGEF?BF<4;A@EE/?;AB>7;7;>@?>B?''5<@;@?;0((4:@>34@@>:4<@>BAB@(948&+
+SRR9130495.119,D00236:723:HG32CBCX2:1:1108:4831:2078/1,GCGAAGAAAACTGAAAAAGGTGGAAAATTTAGAAATGTCCACTGTAGGACGTGGAATATGGCAAGAAAACTGAAAATCATGGAAAATGAGAAACATCCACT,CCCFFFFFGFHHFFHGIHDICFHIGGIDHIIJJJJIIIIIGIGHGIJJJJJJJJJJJIJJJIJJIHHHHHFFFFFEEEEEEEDDDDDDDDDDDDDDDDCDD
+SRR9130495.120,D00236:723:HG32CBCX2:1:1108:4877:2117/1,GCATAATGTTGCCACTGCACTCCAGCTGGGACGACAAAGACTGTCTCTAAAAAAGTAATAAATAAATAAAAGTTTGAAATGCATTGTCCTAGGTTTTAGTC,CCCFFDEFHHHHHIIJJJJJIJIIIGIJJJJJJIIJIJJJIJJJJJJJJJJJJJIIHHGHHHHHFDFFFFFEEEEEEDDDDDCEEDEEDDDDDCDDDDDDD
+SRR9130495.121,D00236:723:HG32CBCX2:1:1108:4918:2158/1,AAACATGTCAATGGCCAAAAAAAACAGACAATCAAAAAATGGACAAATATATGAACAGACATTTCTCACAAGAGGACATACAAATGGCCAGCAAATATATA,CCCFFFFDHHGHHIIJIJJJIIIJJJJJJJIJJIJJJIIJJJJIJJIJJIHGFHHHHFFFFFEFEEEEEDDDDDDDDCDDDDDDDCCBCDDDDDDDDEEEE
+SRR9130495.122,D00236:723:HG32CBCX2:1:1108:4939:2211/1,CCTGGTCTCAGCATTCCTCACACGTCATAGCGAGGCCCATGGCTGTAGAAATCCCACCATTCTCTTCTCCCCAGGCCTGGCATCCGTAGAAGCCTACAGCT,@CCFFFFFHHHHDHIDIHIJIJJJJJIGGEGIJIIGIIIJJJGGIJJJJIGGHGIIIJJGHHHHHFFFFEFDEDDDDDDBDDDDDDDDD?CDDDDDDDDAC
+SRR9130495.123,D00236:723:HG32CBCX2:1:1108:5169:2188/1,TCTGACCCCATGTCCTCAGGCCAGAACCCGGGAGCCTGTCAGAAAAGGTCTCTCACCTAGAGTCCATGCTCTGGAAGCTCCAGGAGGACCTGCAGAGGGTG,??@DD?DFHDFHFIIIIGFHEGGDFFHIBHGIAFIGGIIIFI@CHE@FGH@CDGGIFHEEFCCED@DEEEECCCCCCCCCCCCCCBB8ABC?ACAAABBBB
+SRR9130495.124,D00236:723:HG32CBCX2:1:1108:5192:2231/1,ACTCTCCTGGCCCACGAGAGAGTCCACACAGGAGAGAAACCTTACCAGTGTCATGAGTGCGGCAAGAACTTTAGTCAGAAATCCTACCTTCAAAGCCATCA,CCCFFFFFHFHHGJJGEFGHGIIEIIFJJJIHGIJIIJIIIJIIGIEHHIGIHIJIIJIIBDFDDDDDDDDDCDDDCCDDDDDDDCDDCDDDDDCDDDDDA
+SRR9130495.125,D00236:723:HG32CBCX2:1:1108:5408:2041/1,TGTGTGCATCCTCATGTGTCCTTGATAAGTGGTGTGATAAATGAAGGCTTTGCCACATTCCTTACACATGTAGGGCTTCTCTCCAGTGTGAGTCCTCTCAT,@@@DDDEBFHHHHIIIHIFHIDHIIIJHHJIHEGFIIHIJJIIJJEIJGHHIEIEGIIJIJJJGIGHGJJIIGIGIHJEHHHHHFFEFFFCC@CEEDDDDE
+SRR9130495.126,D00236:723:HG32CBCX2:1:1108:5351:2057/1,CTCTATATATTTTAACAAATGCATAATGTCATGTGTTTACCATTACAGTAGGATAAAGAACAGTCTCATTGCCTTAAAAAGTTCCCTAACATTTTAATTGT,CCCFFDEDFHHHHJIJIIJJJIJJJHJJJJIJIIIHHIJIJIJJJJIIHIJJIIJJJJJIJJJJJJIJIJIJIIJJJJJJJGGIGHHFHFFFFFFFEEEEE
+SRR9130495.127,D00236:723:HG32CBCX2:1:1108:5475:2108/1,AGCCCAGAAGGCTGGACACACCTCCCCCTCACCCCATCCCGCTCCCCAATCAACCCAGTCCTCAAGAAGCACACTGTGGCTGCTTGCTCTCTTGCCCCCCT,CCCFFDFFHGHGHJJIJJJIGIIIHIGIIJIIJJJIJJJHGIJIJIIIJHHGHHFFEDEEEECCDDDDDDDDDDDDDDDDDDDDDDDDDDCCDCDDDDDDB
+SRR9130495.128,D00236:723:HG32CBCX2:1:1108:5542:2138/1,TGGCTAGCTACTGCTGCTGCTGCATCAAAGCCCAAATATTCACTGGCATCAGCTGTTTTGTTCTTTAGCATATTAGTAAAGTGCTCATTTAGAGACATCTT,@CCFFFFFHHHHGJIJJIJJJIJJJJJJJJJJJJJJIGGIJJJJJHJJJJJJJJJHIEIIJJJIIJJJIJIIJJJJHHHHHHHF@DFFFFEDEEEEDDCDD
+SRR9130495.129,D00236:723:HG32CBCX2:1:1108:5707:2147/1,CCAGCATCACTCATGGAACCGGAGGCACTAAGGCCCCTCGGGAGACGCTGAGCAGGTGGGTAGAGGCATACTTCTGGGAGATGGCATCAAGAGCCAGTCAA,CC@FFDDFFDHG>FFFHGGIJIEIIIHIGIGHBHCEHGGGFH@FHGIHHFBFDEEDDEDDDDBDC?BBDCDDDDDC:?A?BDDDCCDC>ACDDDBDDACCC
+SRR9130495.130,D00236:723:HG32CBCX2:1:1108:5614:2168/1,AAACCATGTCTCTACTAAAACTACAAAAATTAGCTGGGCAACATGGTGGGTGCCTGTATCCCAGCTACCTGGGAGGGTGAGGCACGAGAATCACTTGAACC,CCCFFFFFHHHHHIJJJJIJGJIJJJIJJJJIJJJJJIJJJJIJJHIIHJIJJJJJJJJJJJJJJJJGHFHHF@DDDDDDDDDDDDDDDBDDDDDDDDDDD
+SRR9130495.131,D00236:723:HG32CBCX2:1:1108:5985:2027/1,GCGGCAGCGGCCGCGATGGAAGAACTTACGGCGTTCGTCTCCAAGTCTTTTGACCAGAAAGTGAAGGAGAAGAAGGAGGCCATCACGTACCGGGAGGTGCT,CCCFFFDDHHDGHFIJFHFFHHBFGHGEIJJJFFDDDDDDDDDDD@CCDCDDDDDAAACACDC@CCDBB<BDDDCDDDDBDDDDDDDDDBDDDD<>BDBD@
+SRR9130495.132,D00236:723:HG32CBCX2:1:1108:5816:2071/1,TTTACATATAAGAACCTGATGACCTTTTGTTTTTGTCCAGGAGAGTCCTTCTTGTCTACGAAATGCAGCTATCACAGCAGCTGGACTTGTTTCCTGAATGC,C@CFFDDAFFFHHHHHHGFIHJIJFHHHCAAEHIGHJGCCGHIHEHJJJEHGIIIFIGBBAEHGIJIGIIHHEHHHFFFFEECCABCDCCCCACDDACDA:
+SRR9130495.133,D00236:723:HG32CBCX2:1:1108:5835:2081/1,CCAGGGCTCCAAGGGGCTGGTTACGAAGTGTCTCCTGCTGCATGAGGTCCCCACGGGAGAGATTGTGGTCCGCCTTGACCTGCAGTTGTTTGATGAGCCGT,@CCDDDFFHHHGHGJGJFHIEHIGCGHIGJGIIIJJJJJJJJJIIIEIJFGIJJIJG<?BC7>CCDDBDDCDDDBDDDDCDDDDDDDD>BACDDDEDDCBD
+SRR9130495.134,D00236:723:HG32CBCX2:1:1108:5841:2101/1,GGGCATGGTGGCATGCGCCTGTAGTCCCAGCTATTCGGGAAGCTGAGGCAGGAAAATCTCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCAAGCTTGCA,@CCF?BDDHFHGHIIIIIIIIIGHGHHIIIFIIIIIGGFGGIIIIEFGGEGHCD>CGGFHHHGGHFFFCDDADDDDDDDBDBCDCCCCA@CCCCBDDDDDD
+SRR9130495.135,D00236:723:HG32CBCX2:1:1108:6165:2044/1,TTTATACCATTTTTTTTTTTAGCATATATCCTTGTACTTTATAGGAATTATTTGCTTTATTCTCTTGTGACTTGTAAATTGATGTACTTAATTAAATCTTT,"@@CBAB;DHFFHHIGIIGGHGFF@?BGB@8=FHEGHIGD=@CGHIA;@EHFHGHBFFFCBD;>(>@A@C>>;>CA;;35>@3;>5>,;3>:;(:@:>:@@C"
+SRR9130495.136,D00236:723:HG32CBCX2:1:1108:6059:2069/1,CTATGACCGCTATGTTGCCATCTGTAGCCCACTGCTTTATAACACTGTAATGTCCCACAAGGTCTGTTCCATAATGATGGCTGTGGTATACTCACTGGGCT,CCBFFDBEHHHHFEGIIGHGIIIJIIHIJIFIJJJJJJJJJJIIJJIJJJJIIHHIJIIIFIHIJFIGIIIHGGHHHHFFFFDEEEEEDEFEDDDCDDDBC
+SRR9130495.137,D00236:723:HG32CBCX2:1:1108:6161:2181/1,ATGAAGCAACAACCTTATAGGCATTTTAACTCATAGGTTTTAAAACTTAAGGTTATTTTCATAGGAGTCCCTTTTAGCAGAAATGCTCACCACAGGACCAG,@@C<DDDEHFDDHGGBFHIHHIGIEIIHGHEFGHHHE9?C?DFG>GGDD@4???BDHCH@GH<=FHGEGGGIGCEG@E7ACH@:77?C@A@CBAA???2<A
+SRR9130495.138,D00236:723:HG32CBCX2:1:1108:6485:2147/1,TTGTGCATGCATATCTGGATATGTATCACTAAAGATAATTAAATACAGCAGGTCAAAGATCAGTAACAACCATTAACCAAAAACCAAATAAGCCAAAACCT,@@?DDEFFGFHGAHHGBFHHIIJJHIJJEGIJJGHHJJJJJJJJJJIGIGEIGIEIJJJJJIJHIEFGGGIJIJHIIIEIGHHHFFFCCECEC??CCDDDC
+SRR9130495.139,D00236:723:HG32CBCX2:1:1108:6335:2229/1,TTTAAAAAAGATATTTGATATAATTTCAAACTTACCGAATTTGGTAAGCCTTGTTTAGATCGGAAGAGCACACGTCTGAACTCCAGTCACCACTTCGAATC,@@@DFEFFHHFHHIGIIGGGHGGGIIGIIGGHH@FCGHGGJIIIIFHECGHFHIJIJIGGIHGGIGEHGHBDDBCACDDCCDDDDDDDDCCDACCAB<A@?
+SRR9130495.140,D00236:723:HG32CBCX2:1:1108:6596:2108/1,CTGGTGACCAAACACACCTGCGTGGCTTTCTGCTAGTGAACCCCCTTTCTGTCAAAACAAGCCCTCGGGCGGCCTCCTGTCCACCCTAGCCTGGCAGGTCA,CCCFFADFHDFHHJJJJJJJJFJJIIJJJJJIIIHIIIIHGGIJJHHJGIJCHGGIGHJHHHGFFFDDCDDDBBDDDDDDDDDDDDDCCDDDDDBDDC?C@
+SRR9130495.141,D00236:723:HG32CBCX2:1:1108:6612:2130/1,TTCTACCTGGCAATGCTCCTGTTCATGTTGTTCCTTTGCATGCTGCCCACCATTTTTGCCATTGTCCACTACAAGCCGTCTCTGAACTGTGGTCCCTTCAG,CCCFFFFFHHFFHGJJJJIJJHIJIGIIGIIJIJJIHIJIJJEHIJJJJJIJJJJJIIJIIJHHIJIBGIJJFHIHHHFFFEEEEEEDDDDDDDDDCCDCD
+SRR9130495.142,D00236:723:HG32CBCX2:1:1108:6763:2034/1,GATGCTGTCATAGACATTTCGTCCCCACATAACTGCTTTGACAATGCTTGTAAAGTTGTCATCTGTGAGAATAATATCAGACGCTTCTTTAGCCACATCAG,CCCDDDDDHHHGGIJIJJJIJJJJGGIJJGIEIJJIJJJIGGIJIJJJJGIGIIIJIJJJJIIIIIJJIJ@FG@EHIGJHHHHBFDCEDEEDDDDDDDCCC
+SRR9130495.143,D00236:723:HG32CBCX2:1:1108:6781:2064/1,AAGGGAGTCGGGGCAGCGGGGCGTGGCAGAGCGGGGAGCTGGACTGTGGTGTAGCTGCGACAGGGCCTTGGCTGACACCTAGATCCCAAGAGTTTAAGCAA,@?@FF=ADH>FFFIGIIGIIIIFDADBDDDDDDDBBBBBBCDD@CDDDD?BDDDDDDCDDBDDDBDDDCCCCCBBCCCDCCCCDDAC>ABDDDCDDDDA@C
+SRR9130495.144,D00236:723:HG32CBCX2:1:1108:6837:2146/1,CCTGTTATTTTAGTTGTTAAAGGTGGCATTCTGTTCTTGTGGCTGTCTTCTTTTAGGTTTGTTGAGGGATTACCTTCTTGTTTTTTCTAGGGCATTGTTCC,BCCFDDFDHFDHFGIIIIJIGIIJJIDGHIJIIJJJJJJGFIIIHFHHIJJJIGDGIGHGHIJICHGGEHGCHGFEHFHHFDDDDDDDDDDDC?CDDDDCC
+SRR9130495.145,D00236:723:HG32CBCX2:1:1108:6804:2189/1,TGAATCTCTCTTGGCCTCCTCCCCTCTCATGTCCCCTCCTCCCTCCTCTCCACTTACTCCTCCTCCTCCCCTCCCTCCTCCCAGATGGTTCTGTGTCTTTT,CCCFFEFFHHGHHJJJIJJIJJJJIJJJJJIJIFIJIGIIGGJIJJIIIIIGIIJIJIJGIIIJIJJHHHFDFFDCDCCDDDCDBCCDCDDD@ACCCDDDD
+SRR9130495.146,D00236:723:HG32CBCX2:1:1108:6940:2229/1,CTTAATGCCACTATCACCACTTCCTTCAAGAGTGAGGGAGAGGAAGAGGAGGAAGAGGAGGAGGAAGAAGAGGAGGAGGAGGAAGAGGAGGGTGAAGGGGA,@@@DBDDEFHHHHGIJIEGGIGECHIFIIJGFHHACCF?D:DFF;?FHH9DFCGGHFG@CA?AB?DD>?A@BDDBB=?B5<B5?AAAB8?BB??8@ADBB5
+SRR9130495.147,D00236:723:HG32CBCX2:1:1108:6772:2250/1,GAGGAAGGAAGGAAGGAAGAAGGGAGAGAGGAAGAGAGGGAGGGAGAAAGAAAGGGAAGGAGGAAGGGAGGGAAGGAAGGAGGAAGGAAGAAGAGGGAAGA,?<???DDDF;AF:CEHCAC+ACFFCGFGFHGEII@BGFFG@;FB;@HECE?E>@BBFCAA@A;;5?BB9;=>;BB?1>A?ABD<BBDBDDBACCDDDBA?A
+SRR9130495.148,D00236:723:HG32CBCX2:1:1108:7203:2046/1,CCCAGGCTGGTGTGCAATGGCGCGATCCCGGCTCACTGCAAGCTCCGCCCCCCAGGTTCAAGCAATTCTAGATCGGAAGAGCACACGTCTGAACTCCAGTC,@CCFDDFFHFHHHGIIJIHIIGHGGGIJGJEGGHGIJIGIGGGHIIJJIGEDBB?@ACCDEACBCCDDDEDDDDDDDDDDDDDDDDDDDDD<AC@CCC>CC
+SRR9130495.149,D00236:723:HG32CBCX2:1:1108:7167:2101/1,TTTCATGTTTTAGGTCTTGTAAGCAAGATTTTTCCTGTTGAAAAACTGGTTGAAGAAGCCATCCAATGTGCAGAAAAAATTGCCAGCAATTCTAAAATCGT,?@?DB?DDHHGDHIHHGBIECFDHHE>C<ACFA@FE?:CEH<DGIIEECBGHGGIIHGIIIEFHF=@@FHHIIIIHHHDFFCECCCDDDDC@@C@C:@@?B
+SRR9130495.150,D00236:723:HG32CBCX2:1:1108:7286:2036/1,CCCATTCTTTTCTGGTGAAGGCAAACTGCCCCATCCCCTTATTGGGAAGGGATCTTCTAGCCAAAGTGAGGACCTCTATTTCCTTTGACCCTTCCCCCAAT,CCCFFFFFHGHHHJJJJJJIJIJIIJGHHIIIJJIDIJJIIGIHEHGIDHIIEHIJFHIJIJJIJIJJGHFEHFFFFEEEEEDEEDCDDDBDDDCDCDDDD
+SRR9130495.151,D00236:723:HG32CBCX2:1:1108:7407:2109/1,CAAGTATCCCTTGTTCTCCCTTGTGATGATTAGGGTGAGAATGTCCCCAGGAGGCTCAGATGTTTGAACACATAGTCCCCAGTTGGTGGCGCTATTTGGGG,1:?BBADD<?CBCFHABCAAFEC<ACHEEHIII<CEDFHHIHHCC?BD@GGEHGHIIICHHF@GCGDCGHEGHA??>7?BB7;@A(5==;88323>CDC9B
+SRR9130495.152,D00236:723:HG32CBCX2:1:1108:7449:2110/1,GGCTTCAGGAGCTTCAGAAGTTAAGAGCTGCAAAAAAGAAGAAAAAGGATCGGCCAAGTAAAGACTGTTCCAAGTTGGACATGCTTGCTAGAAATTTCCAG,CCCFFDFEHGHHGJIIBEEHHIIIHHIGGJIIJIIGIIGGHIIIJIGGGGGGGIIJJHHFHHGFFFFFEEEEEEEDDDDDDDCDDEDDDDDDDDDDDDEDC
+SRR9130495.153,D00236:723:HG32CBCX2:1:1108:7499:2197/1,TTCTCATAGTTCAGCTTCCACTTGCGGTAGCTTGTTCCACTTGCGGAACATGTGGTGTTTGGTTTTTTGTACCTGCACTAGTTTGCTGAGAAAGATCGGAA,@@@DDDDEHHFFHABECCAFHHHFDGIHJIIEFGHIIGIGEHEBGG0AEDHGFFFGIDG@EH=ADEBADDE@CCCBCACDDDEEDDCCCBCCC@CC>AB@@
+SRR9130495.154,D00236:723:HG32CBCX2:1:1108:7309:2205/1,GGAGGCTGAGGCAGGAGAATCGCTTGGACCCGGGAGGTGTAGGTTGCAGTGAGCCAAGATTGCGCCACTGCACTCCAGCCTGGGTGACAAAGTGAGATATT,BC@FFFDFDHHGFIGIIIJIJJJJJIJJJIIJJJIIIHHIJIJJJIJHHHHGHFFFEBAEECEDDB:@CDDDDCDDDDDDDDDBCBDCDCDDDCD<A@CDD
+SRR9130495.155,D00236:723:HG32CBCX2:1:1108:7701:2002/1,CTGCGCCGGCCAAAATCCATCCAGCCCATGTAGTCCCGGTCACTTATTCTATGGCTGGGGTCCAGGCTCTGCAGGTTCTTAAGAACGGACATGCGGCCAGA,;@?ADDDFFHGDFHIJJJJIGGBEI?;FHIIFIGHA@@;F;;CDH)=ECACHHCD9B<AC>BDCC?A<ACCDDDB9:3>CDD34>C@BD<>>:CB<>@BA8
+SRR9130495.156,D00236:723:HG32CBCX2:1:1108:7518:2119/1,TTATCAAAGAGGCCCAAGAGAAACCACTTGTCTGACTTCTACCATATGAGTTTAGAATAAGATGATGGCTGCCTATGAGGAAGCAGGCCCTCAACAGATAC,@@@DDBD4CFFAAHII=G9FDHG;?F@;EEBEFCF>BGBGD<F?DCHEFB?FGGB@HAHIG)8=CCGCDGIIHHH@HFED>BECC@BBBBBBBCCABC@CC
+SRR9130495.157,D00236:723:HG32CBCX2:1:1108:7577:2169/1,AGTTACTTAATATACCTTAGCCGAAACTTCTGCACTGATTTCCTCCTGTGTTTCAGCCAGCCGCTTTTTGGCAAGTTCGGTTCTCCGATCACACTCTGCAA,@@@DDDFFFFHGHIICGHFH@FGGHGHHJGIHJIJIJGIIIBDHCBGGHEHIJJIGIIIBGIEIGGHHCEBDFEDECD?@DDDDDDDDDDBCCDDDDDDC>
+SRR9130495.158,D00236:723:HG32CBCX2:1:1108:7659:2196/1,TTCTGATTTTTGCTGCAGCTTCTGCTTATAATCATATGGCCAGTTGTGCTTGTCAGAGTAATGGTGAAGTCCACAAAACAAATTTCCACATCGGCAGTCAA,CCCFDDDDHDFHFGIFCHIII9FHHIGGHHIJJJJIJJEHGEGIIJJJJJJJJDHGI:DFGIIGHGJGCGHGIJJGIIHGHGFFECB@CEC@B@BDD?CCD
+SRR9130495.159,D00236:723:HG32CBCX2:1:1108:7733:2213/1,GGCCAGATGTTTCTGTAAAGATTGAATTAGATCCCCAGGGAGAGGCAGCACAAAGTGCAAATGAATCAAAAACTGAGTAGAATATTGTAGAGTGCCAATTA,@<@DDA+AFFHHHIIFBHC@@F<FHHHEGIIIIIGI;?:D?:DDGHGICGG;F8=BGIED@FEDECGEAEAE8@?BCECC@@@ADDACDC;ACC>>@>CC:
+SRR9130495.160,D00236:723:HG32CBCX2:1:1108:7590:2217/1,GGGGCTGGGCCCACCTGGGACAGAGGGCCACATGTAGAGGCAGCGCTCCCCCGTCTTGAGCTGATCTTTGCAGTCGAATAGCATGAGGTTGGCCCAAGCGA,CC@FFDDDGHHDHIJDGII<GIDGEHIIIJGIIGIEGGIJJIEIJGIHIFHHFCDDDDDDDCDCCDECDC(;@C9=8?C?CDDEDACD>ACBDDBBBDDD@
+SRR9130495.161,D00236:723:HG32CBCX2:1:1108:7735:2228/1,GCAGCACTGTCTGAGTATGGGAGCAAAGCCTAATCTGGCTTGCCCGGCCTCTCACCTCTGTGGCGCTCTGCATCATGGTGCTTCTTGTCATCTTTTATTGC,?@;DDDDDFCFFHIHHGBHIBH?FHIBDEHB@GEIHIEHGHAFFHGEEH<CEHIGIGIGGIFFC<><<?CCCCCCCFCCCCA@@CCCCCA5>@CC@C@CCA
+SRR9130495.162,D00236:723:HG32CBCX2:1:1108:7898:2065/1,GTTGGCTTCCCCCTCCCCTCTCCCGTGAGCTGAAAAGCAACAAGGGCTCCACCAGCCTGCAAAATAAGACTTGGGGGGGGGGGGGCAGGGATTGCTTTTTT,@@@FDDDDHHFHFIJIFHIIJJJDHFGIGIGJAFHIDG>@GGFHGGHJIGCHIIGEEHFGF@CFEECC>;>CCABBD<99B@BD99&)&&+9(3(4>(+:0
+SRR9130495.163,D00236:723:HG32CBCX2:1:1108:7872:2066/1,CACGCTGGATGAGTTCCTGTTCAGCGACCTGCAGGCGCTGGAAGTGCTGTTGCTCTACAATAACCACATTGTGGTGGTGGACCGGAATGCCTTTGAGGACA,CCCFFFFFGHGGHJJJJJJJJJJIJJJJJJHJJJJJIJJIJJJIGIJJIJJJJIHHHHHHFFDFFEDDEEEEDDDDBDDDDDDDDDDDDDDDDDDDDDDDD
+SRR9130495.164,D00236:723:HG32CBCX2:1:1108:7826:2191/1,ATCTCTGGACCCAAACTGGAGGGTGACATTAAAGTTCCCAGGGTGGATTTGAAGGGCCCAGAAGTGGACATTTCTGCTCCCAAGGTCAATATTGATGGGAA,CCCFFEFFGHHGHIHHIIJIIIJJIJIGIIJIHIGIJJJJIJJBFGGIJJIJJJJJIJIHFHHFFF@EEDEEFEEDDDDDDDDDBACDDF@CDEDEDDBDD
+SRR9130495.165,D00236:723:HG32CBCX2:1:1108:7791:2195/1,GGAGAACAGCGTGTAGAGCACTCACAGTCTGCTGCCTTCAGGTGTGGGAGGCACTGCTCACACTGATCTTCTTCCCGGTGTGTGTGGTGTTTGCCTGGATG,CCCFFDEFFGHHHJDIIJJIFJJJJJIJJJGIJJIIJIIIJIJIIGEGHHJJJJJIIFIJJJHHHHFHFFDDFFEDC>9;?BBDDD?CDDDDDDDCC?BDC
+SRR9130495.166,D00236:723:HG32CBCX2:1:1108:7767:2199/1,GACTAGCCTGGCCAACATGGCAAAACCCAGTCTCTATTAAAAATACAAAAATTAGCTGGGCATGGTGGTGCACGCCTGTAGTCCCAGCTATTCAAGAGGCT,@@@DDDFFFHHFBHBHBDEHHGGGHIIJIIHIHJIEEEIGHEIHIIGHIIHHGJIEHGI?G@CDHI=CA?BDFF<?ABCDDC@CDA>ACDCCDFCC32??A
+SRR9130495.167,D00236:723:HG32CBCX2:1:1108:7824:2210/1,GCACCACCGTGCCTGGCTAATTTTTATATATTTAGTAGAGATTGGGTTTCACTGTGTTGGCCAGGCTGATCTTGAACTCTGGACCTCAGGTGATCCTCCCG,@@@FFDDFDFAHHJJIJIIGHHHHHIIJIIDGG>GHHIGGCGHGIEHGGH>FFHJJJHDGBGHJCGGGHFEHHHHFFFFFECDECEDDDCDDDDCCDDCDD
+SRR9130495.168,D00236:723:HG32CBCX2:1:1108:8205:2084/1,CTTAGCCGCTGGTGATGCTAAGGGCATGGTCAAAGTGTGGCAGCTGAGCACAGCCTTCACAGAACAAGGGCCCCGGGAGGTGGAGGACTTGGATCAGCTAG,CCCFFDEDFFHHHJEGIDHHIIIIJJJIJGIJJJGHJIJIJJJIIIJIGGIIGIJJIGHIIJGEFHGBEFDDDBDDD;>B2<@BBDBBCCCCDDDDDDDDD
+SRR9130495.169,D00236:723:HG32CBCX2:1:1108:8202:2124/1,GAGACTCTTGCACACATACCGGGGAGCTGGCTCACCCTGGCCCCTCCATCCTGTCAGACTGAAGAGAACAAGTGTCTTAATTTGGGTTTTTCTTATTATTA,CCCFFEFDHFHGHGJIIIJJIJJJIIIGIJJJJFIJJHGIJGHIIJJEEEHFGFFEFECCEEEEDDDDCC<A:>AD>CCDDDDCCD<?BBBDDDDDEEED@
+SRR9130495.170,D00236:723:HG32CBCX2:1:1108:8398:2058/1,TTATCTCACTTTATTCTCGTTCTCCTCGGACCTCCGTAGCCATATCACTTGTATAAAATAGGCTGAGATATAGTGACTGTAAGCTGTGATCTCAGTATTCA,@@@FDDFEHHGHHJEGFDEHIGIIJJIJFIIIIGHIDFCGBEGCGHGGGIDHJJGGGJIJE@HHGEECECEHCFFFEFF@CDEDCEDC(;@ACCDCADDDD
+SRR9130495.171,D00236:723:HG32CBCX2:1:1108:8469:2081/1,ATGGCAGCCTCCAGCCGCGCACAAGTTTTAGATCTGTACCGGGCGATGATGAGAGAGAGCAAGCATTTCAGCGCCTACAATTACAGGTGACCCGGGGGGAG,@@@DFBDDHFHGHIBFBFGIJIIGHH@GFFHGIJIIIJHIII8GHDDDC@CEDDDBDDDDDCDDDDDDC@CC9@BDDDCD@CDDDDDCCDDCDDDD@@B<B
+SRR9130495.172,D00236:723:HG32CBCX2:1:1108:8385:2092/1,CTTGTTGCTCATACTACCTCCCTCCCCAGTAACTTTGACACAATTCTCATGTGCCCTGCAGCTAGCAATGTCTCTCGTCTTCATCCTCCCTCTCAGAAAAT,CCCFFFFFHHGHFIJJJIIDIJJJJJJIIJJJJJJJJJJIIJIGIJJIJJIIHIJJJJJIJJIIGJIIEIIJJJHHHHDFFEEEEEEDDDDDDDDCCDCCC
+SRR9130495.173,D00236:723:HG32CBCX2:1:1108:8470:2098/1,CATGCCCCTGCTAACATCAATGCCCAGAAGGAAACCGTCAACCAGCAGCTTCCCATCTGGCATCTGTTTCTGCTCAAAGTCTTGCTCCAGTCCCAGCTGGT,CCCFFDADHHHHHGIIGGHEHIJJJJIJIIIIBFHIIHJGHIIGHFHIJIEHIIGIGIJIJHGHHHHHHHFFFFFEEECDEEECDDDDD@CCACCDDDCD<
+SRR9130495.174,D00236:723:HG32CBCX2:1:1108:8304:2120/1,CTAGTACGGCAAGGCCGAACCATCTCATACCAGGGTTGTGCCTCACAGATTTTCTTCTATCACACCCTGGGCTGTACTGAGTGCTTCCTGTATACAGTGAT,CCCFFDDFHHHGFGJJJJIIHIHJJJIJJIHIGCGHIIIJIIIIJIHIJIIHGHHHHHFFFFFFDDCDDDDDDBDCDEDCDDDDEDDDDDDDEDEED@CDE
+SRR9130495.175,D00236:723:HG32CBCX2:1:1108:8713:2027/1,CCTCCTGGGCCGCCCCAATGAAGGAGCCAGATGCCATCAAGCTGTTTGTGGGGCAGATCCCGAGGCATCTGGAGGAAAAGGACCTGAAGCCCATCTTCGAG,@@<:BADDBDHHHH<FG??CCGHHIIFG99BB8*988B=<BE3=8=CC6CC<BDB>?@@A=?8=?=BA93>CA??B@A????8<CCA:@:<<@CCCCD8(3
+SRR9130495.176,D00236:723:HG32CBCX2:1:1108:8742:2116/1,GGCCGACACTCAGACACTCATTAGAAGGACACTGAGGATACCATCTACCGACCTTTCCGGAAACTAAAGCACCGTTTGATTCTTCTGTATGTAGTTTTGGG,CCCFFFFFHHHGHIJJJJJJJGIJIJFIIIJJIFIJIJIIIJJJIJIGIIJJJJIIHHHGFFDEEEDDCDDCDD??C@CDDEDEDCDDEEEEECADDCBDD
+SRR9130495.177,D00236:723:HG32CBCX2:1:1108:8654:2133/1,TTCCGCAGGCACTGCCACGTGGTGGTGTAGAGGATGAAGGCAAAGGACTTGAGCGCAATGGCGATGCTGACGTACAGGTATCTGTAGACCACATTGTCGTA,CCCFFFFFHHHHGIFIHJJ@GHDFGDEDHEIIIJGGGICGIIJJJJJJIJJJJIIHHFFDCCDDDDDDCDDBBDDDEDCDEDDDEEDEDDDDDDCDEEDDD
+SRR9130495.178,D00236:723:HG32CBCX2:1:1108:8865:2086/1,CTCCTCCTCCTCCTCCTCCTCCTCCTCCTTCTTCTTTTTTTTTTTTTTTTAACCGAGAAGCGGGCAGAATAATGATCCTGAAAAAGCCCCTGCCTCCGGGA,CCCFFFFFHHHHHJIGGCEFGG@FGEGIGGBHIGGAHGIBGHGIHDDDB0<3((&0-75(+0570&0(+(+((++(4(+:>CD(8&8?()(+224@?@>35
+SRR9130495.179,D00236:723:HG32CBCX2:1:1108:8868:2131/1,GTACATTGTATCTTTGTTCTCATTAGTTTCAGAGAAATTATTGATTTCTGCCTTTATTTCATTATTTACCCAAGAGTGATTTGGAAGCAGGTTGTTCAGTT,<;;B?D>DFC:DBF@AEDHHAHHGH:A:AC4?<E;221?EHI*11????D9D<FH@BFBH??:9BFGIGFCGB=D=@=CHGIBDGA)6.7;;7@566.3;;
+SRR9130495.180,D00236:723:HG32CBCX2:1:1108:8793:2183/1,ACACAGAGACATGTTTGTACATATAGAAGTGTATGTAAGTATAACTTTGTTATGTTACTCAGCCATGACCTTTGGTTTCTGCGTGGCATTCACTCTAGGTT,CCCFFFFFGHHHHJJIIJFFGIIGJJHIIHHIIJJGGIIGJJIIJJJJJHJFIIJJJJJJJFGIIIIJJJIJJEGHIJJJJIGHHBFEEEEEEEDDDDDDD
+SRR9130495.181,D00236:723:HG32CBCX2:1:1108:8880:2229/1,AAAGGTCACCTGAGCCCCATTTGAGTCCCAACAAGCAAGAAAGGAGTCTTTGGACAGTGGTGAATAATCTCAGGCACCCACTTTTCGTTCACATTTTCAAA,CCCFFFFFDFHGGIGIJJIJIHHGJIJIGGIJGJJJJJIEGIGIIJGIIIJJJIJIHIGG@EGIIJGJGHHHHHFEFFDDDBDDCCDDDDCC@CCDCDDDD
+SRR9130495.182,D00236:723:HG32CBCX2:1:1108:9241:2001/1,ATATTTTCTCCTTAAGGTACCACAAGTTGATCTGGGGACCTCATAAGATGGATTCCAAAGGAGATGTTTCTGGAGTTCTGATTGCAGGTGGAGAAAATGGA,@@@DFDD?FCFFHCHGBBDBEHDDABEHG?CH@HGIIHIIIEHEC??FDAGGI9?F<F:FHIHIGFF@GDHIEACAEHHH@@;>BFFEDA?ABD@ACCD:>
+SRR9130495.183,D00236:723:HG32CBCX2:1:1108:9106:2031/1,CTAGAAATCCTGGATTTTCAGCACAATAACTTAGCCAGGCTCTGGAAACGCGCAAACCCCGGTGGTCCCGTTAATTTCCTGAAGGGGCTGTCTCACCTCCA,C@CFFDFFGGHHFJHIIJGIHCCEHHIGIFIIHIJJFIGJIGIJJIIJHIFGIJIJFFHHFDAD@BCCBDDDDBCC@CDDCCDDA<B<BDDDDDEDDDDDC
+SRR9130495.184,D00236:723:HG32CBCX2:1:1108:9233:2138/1,CAGAAGTGGGACAACCTAACAGGACAACTGAGGGACAGATGCGACTGGATTGACCAGGCTATCGTCAAAAGCACACAGTACCAGAGCCTGCTGAGAAGTCT,CCCFFBDDFFFHGJJJJJIJJJIJJIIJIJIJIJIHIIIJIJJIJIIGIJJJGIJJJHHHHHFFFECDDCCDCDDDDDCDCDDDDDDDDDDDDDDDDCDDD
+SRR9130495.185,D00236:723:HG32CBCX2:1:1108:9017:2163/1,TTAGATTCAAACTCTAGCTTCACCACTTTCTTTTTTTTTTTTTTTTTTCGAAAGGGGTCCCCCCTCCCTACCCCAGGCTGGGGTCCAGGGGCCAAATTTTG,<@@BDFDDFBBFBBHEABCEFHGHEH3EFGHIIIIHHIII>EFC'8;&+)+((&28&&&+((&)&&++((++8((2(((25(&&&(++(0&&&(+((+4(+
+SRR9130495.186,D00236:723:HG32CBCX2:1:1108:9230:2213/1,ACTTAGTGCAGTACCCACTATTCCCGCTCAGGCTCCGAATAGTAGATAGAGGGTTCCGATATCTTTGTGATTGGTTGAGAATAATCAACGATTAATGAACA,CCCFFFFEHGFFHFIICIIFIJHHGBHHGIGJJIJGGHIGFHIGIIJJJIIGJCFIJI@EFDFEDFFCCEEEEDDDBDDDDDDDECCDD@BDDDCDDDCDC
+SRR9130495.187,D00236:723:HG32CBCX2:1:1108:9264:2024/1,AACATAAGGTTTCTCATAAAACAAAGAAAAATGTCAATTCAGTTGTGAATTCATATTGATACCTGGAACTCTCCTGCTAGACCACCTCTAAAGGCCCAGGG,CCCFFFFFHHHGHIJJIDJIJJJDHIIJJJJIJJJJJJJIJJGCHIIJJJJJJJJJJIHJJJJJJGIJJIJIJIIIIJJHHHHGFFFFFECEEDDDDBBBB
+SRR9130495.188,D00236:723:HG32CBCX2:1:1108:9293:2034/1,GTGGGGAGGTTTGGGAGTGAGCAGCACACCCCAGTTAGACTCCTGTTGGGTTTCATAGGAGCTGGCTGCTGAATGTAAGAGTGCAGGCTACCCCGGGACTT,@@@FDA;1DAFHFIIFBGIGHGADHIGIIIIIIIIHBFEHIIIIIIIIHIACEEEHHBD@CDECECCBBCCACCCCEECCCCCCCCBBBCCCB?9>>>>BC
+SRR9130495.189,D00236:723:HG32CBCX2:1:1108:9484:2048/1,ATGTAGAGAGAGGGAAAAAAGGAGAGAGAGAAGGATAAAGAGAAGGATGCACAAGAAGACCAAAATACCTGATCATGTAGGGGAGAGCCTCTGGGAGAAGG,@@@DFDDDCDDFHICFHHDGIIHHCHCFFDGHHDCGIJIH@FFHFHGIIGIJIGIGF@CEBDFF@EECDCCCCCCDDEEEDDDDDDDDDDCDDCD<@BDCB
+SRR9130495.190,D00236:723:HG32CBCX2:1:1108:9388:2219/1,AGCTGCTGCGAGATGGTGGCTTGCATCTCCTTGGACGGCCGCTTGTTCTCCTTGAAGATGGCAATCAGCGTGCGGCGCTGCAGGTCTGTGAACACGAGGCG,"B?<DDF8BFAFCAAF93A19?;?B94?DCDHG49BDDG8BH;/5;AE>>3=?>;@DF@>CACC>;>@A>',,88>>-09599(+8>C<CDEC@>95>>>00"
+SRR9130495.191,D00236:723:HG32CBCX2:1:1108:9404:2245/1,TCCGGCTGGTACCTTCATAACTACAGTAATAGAAGACATTGAGTGCCTCCACCGCAGCTGGCCCTCTCTGTTTGTAGCCAAAGATCAGATCTATCCATTCA,CCCFFFFFHHHHHJJIJIIJEIIJJJJJIJJJIJJJIJIIIIIJJJIJJIIJJJJEIJJIHIGHHHFFFFFFDEEEEEDDDDDDDDDDDDDEDCDDDCDCC
+SRR9130495.192,D00236:723:HG32CBCX2:1:1108:9632:2134/1,ATAGTGGCTGCTGATGGATGTGCTCTATGCAAGGGAGGTGCTCACTATTTCTGTTCGTCAATTTGTAACCCACGGGAGGAAAGGGAACAAAGAGTGAACAA,CCCFFFFFHHHGAEFFHIICHGIJHGFIIIHIJDGIJJIIIEGIJJIIFHEGHGIICHIIFIJJJJIIJJHHHFFDBDD?BDDDDBDBDDBCDD:@CCCCD
+SRR9130495.193,D00236:723:HG32CBCX2:1:1108:9647:2175/1,AATACCAGCCCAAGACTTTGGGAGAAGGGAAGAAAACAAAGTAAAATAACTTACCACTTTGGCCCAGTCCGAGAACAAGTGAAAATACCCAGGCTGCCCCA,CCCFFFDFGHHFHIIJJGIIIJDIIJIJJJJIIHIIIIJJJHCFHHFHIJJJJJJGIHJJJIJJHGHHHFFFDDDDDCD>CCDDDDDDCDDDBDDDDDDDD
+SRR9130495.194,D00236:723:HG32CBCX2:1:1108:9552:2194/1,CCATGCCGACACAGGTAGATGGTACGGGGCTGCACGTGGATGTTCATCAGGTAGTATACAATTCGGCTCTGGATGTGGTCCTGCACTCTGTTCACCAAGAA,@@CFFFFFGHGHHJJJIJJJJIJJJIGHFEGGIFIJIJIIIIIJJIIJJIHHHHHHHFFFFFFFDCDDDC@@ACDDCDDDDDDDDDDDDCDDD@CCDDDDD
+SRR9130495.195,D00236:723:HG32CBCX2:1:1108:9620:2235/1,CCAATGATGGCCAACTAGGCCATCTTCTACTATGTACGCAGCTAGAGGCACGAGCGCTGGGGGTACCGATTAGTTCATATTGGTGTTCCACCTATAGGGTT,"===BD?DBAABD8AC3<E9>?F?D9C<?AA94*@?C<DG706BG**926B;;F>6'5;:>7<<>8:(',&22>(((:>3>+:(+28(43>@B(>:>A((32"
+SRR9130495.196,D00236:723:HG32CBCX2:1:1108:9908:2124/1,TCTTGTGAAGAAGATGCTGTTGGAAGCCTCTAAGAAGCCCGAACTGAATGCTCTTATAAACAATACCAGAGGAATTATTTTTTACAGTGTCCCTCACCATG,CCCFFFFFHGDFGIIJJIJJIGGJJIIJJIIJHIIIIJJJJI>HHIFIJIJIJJIIHIHIJJJJIHIHHHGFDEFFEEEEEEDDDDDFDEDCCDCDDDDDD
+SRR9130495.197,D00236:723:HG32CBCX2:1:1108:9923:2206/1,TGGGGCTGTGAACCGAAGTCTGCTCCTTTGCGTGAGCCACCCCTGCAGCCCCTCCCACAGTTCCTGAGGAGCCTTTAGTCCTCGTCCTTTCTCAGCTGTAT,@BCFFDAFHHHHHIIIIHIIJIIJIIJJJIIIJJIGGIIIJJFGGGGGEIIIGFHHEFFFEECCCC@CB@BDDDCDDCCDCCDDABBBCDDCC@CCDCCCD
+SRR9130495.198,D00236:723:HG32CBCX2:1:1108:10131:2036/1,ATGTGCTCAAAGGCTGGGTGGACCTTACCTCCAGTAAACCCCACGTTGTGAAGAAATCCATCAAGTACCTGGAACAAGGAACTCAAGACACCAAAGATGTG,@CCFFFDDFFBHDHIIIBFEGFGHGHGDFHFGIJJIIHDGEGHIJHFHIIIIJJJJJIIIFHHHFHFFFFFFBAEAACBBCADDDDDDDDADBABCCC>AA
+SRR9130495.199,D00236:723:HG32CBCX2:1:1108:10246:2089/1,GCCCTGGGATTGTCCCTCTGGGCACAGGGAGTCCTGGGGTTGTCCCTCTGAGTAGTTCTGTTGGGAGAGGAGGCCCTGGGATTGTCCCTCTGGGTACAGGG,CCCFFBDDHHHFHJIIIJJJJIIIIIFIIEHGIGJIJDHJIJIIJJFJIJ@FFCHJJJBEGEHHHDFDCD@DBB;=?A?@BDDDCACDDDDD@?CCCCDCB
+SRR9130495.200,D00236:723:HG32CBCX2:1:1108:10051:2156/1,ATGGAGGATGGCACCCTGCAGGCTGGCCCAGGAGGTGCCAGTGGGCCTCGTGCCCTGGAAATAAATAAAATGATTTCTTTTTGGAGGAATGCTCATAAACG,@@CDFFDFGFHFFIJGGII<GIJGIJDIIJJIIDDIIIGIJJIJIJJJJBHGGGHC;E;@DCEFDDCCCCCCDCDECCCDCC=;@??8?CAC>CCDDADDB
diff --git a/docs/notebooks/example.fastq b/docs/notebooks/example.fastq
new file mode 100644
index 00000000..4b357e52
--- /dev/null
+++ b/docs/notebooks/example.fastq
@@ -0,0 +1,800 @@
+@SRR9130495.1 D00236:723:HG32CBCX2:1:1108:1330:1935/1
+NCAATACAAAAGCAATATGGGAGAAGCTACCTACCATGCTTAAAAACGCCAATGAGCAGNGATTTGTCANCNNNNNNNNCNNNNNNNNTNNTANNANNCTC
++
+#4BDFDFFHGHGGJJJHIIIIGGIIJGJJGIIIIBHIJJJIIJIJJIJDHIGGGIJJJI#-@AEHGEFF#,########,########+##++##+##+2<
+@SRR9130495.2 D00236:723:HG32CBCX2:1:1108:1472:1938/1
+NGTCAAAGATAAGATCAAAAGGCACTGGCTTACCTGATTAAGAAATTGTGTAGTCCAACATCAAAATACNTNTNNNNNAGAGNCANGNCAAGCNNANNAAT
++
+#1=DDDDD>DHFH@EFHHGHGGFGIIIGIGGGGIIGIIDDCHIIIIIID@FEGGGIIIIICHIIIIIIG#-#-#####,,;;#,5#,#,,8<?##,##++8
+@SRR9130495.3 D00236:723:HG32CBCX2:1:1108:1728:1948/1
+GTTTTCCTCTGGTTATTTCTAGGTACACTGGAAAAGAGTTTGCATTAAAGATTATAGACAAAGCCAAATGCTGTNGNAAGGTACAGTATACACAACTGCTA
++
+@@@DDDFFHHHFHBHIIGJIJIIJIIIEHGIGIJJIIGGIIIJIIJIJIIIIIHIJJIIJJIGHGIJJIGGHC=#-#-5?EBEFFFDEEEFEAEDBCCCDC
+@SRR9130495.4 D00236:723:HG32CBCX2:1:1108:1635:1961/1
+GGGAGGCGCCCCGACCGGCCAGGGCGTGAGCCCCAGCCCCAGCGCCATCCTGGAGCGGCGCGACGTGAAGCCAGATGAGGACCTGGCGGGCAAGGCTGGCG
++
+CCCFFFFFHHHHGHIIIGIIJIIIJJGHFFFFDDDDDDDDDDDDBDDDDBDCCDDDDDDDDDDDBDDDDACDDDDDDDDDDDDDCDDDDDDDDDDDDDDDD
+@SRR9130495.5 D00236:723:HG32CBCX2:1:1108:1605:1988/1
+CACTCCGCCACTACAGCAGTCCCCCAGTGTCATCCGGAGACTTGTGACCATCTCGCCCAACAATAAGCCCAGTGAGTAGGAGGAAAGTCTGGAAATGGGTA
++
+++=A1A:1ADA<;FFDC?;CG<F;::1CFIFCFABF?)77/*8.=FEFFI@38=CC=8<BD=B;36;6.,5?(-:3>5@A:AB@8>@:@A@9(:((+(834
+@SRR9130495.6 D00236:723:HG32CBCX2:1:1108:2392:1965/1
+CGATAAAGGACTTTCAGTCAACCAACTAGATAATGACCACTGGGCACCCATTCATTATGCATGCTGGTAAATAAATTATTCTGTTCAGGAACATTGAACTC
++
+CC@DDDBDFFHHHJJIJJIIJIJJJIIIHGIGGHCGGIGHH<FGHHIGEFHHIGIHHGHIIJJJJEGIGIEEHHHGHHHGFFFDDFFEEEEEDDA@DCCCC
+@SRR9130495.7 D00236:723:HG32CBCX2:1:1108:3536:1968/1
+TGGCAATGGTGTTTCTTCTTATATGATGCTTATATCCAAGGGAGGGCCACATGGAAACTCCAGGGCTCCTGGGTCATGGCAATGGAGTGAGTGGAAAGCTA
++
+@CCFFFFFHHHHHIGIJJIJIJJJIJJJJJJJJJJJJGGIJIIJJJJJJJJJJIJIJJJIIJIJJHHHHFFFFFEEEDDDDDDDDDDDDDDDDCDDDBDDC
+@SRR9130495.8 D00236:723:HG32CBCX2:1:1108:3726:1969/1
+TATTTCTTACTCTTTCAGATGTTACCCTCCCCCGACTTAAGGCCTTCATACCTCAGCTGCTGTCACGGCTGCATATTGAAGCACTTCTCCATGGAAACATA
++
+CCCFFFFFHHHHHJJJJGGIIJIJJHGJJJJJJJJJHIIJHDGGIJJJIIGIJJJJJIIJJJIJJHHHFFDDEDDDEEDDCDDDDDDDDDCDDDDDCDDDD
+@SRR9130495.9 D00236:723:HG32CBCX2:1:1108:3936:1939/1
+NAAACTTTGATGTCCTAGCCCCAGGAGATGGGCACTGGGAAAGTGGTTGATCGGAAAGTAGAGCTTGAANANGNNNNNGGTCNTGAACTCCATNNACNGCT
++
+#4=DFDFFHHHHHIJJJHGIIIJJJJGIIJEIIIIJFGHFHJJHIJGJIIJJJIJJJGGIIEHIGGHHH#,#,#####,,;?#,5??@CCDDD##+2#+8?
+@SRR9130495.10 D00236:723:HG32CBCX2:1:1108:3767:1949/1
+CTGTCAGTACAGTGGGACCCACAGAACAGACTGGATTTTGCAACCTTCCAAGGCAGTGTCTACTACAAGGTGTGNCNGTGGAGAGGTTTCTCAGAGAAGCC
++
+B@@DDBDFDFHHC<F<BGHGBFHGIJIGEGIJIGFAFHCDGIHCGEHEE@AGHGIJHIIIHGDGE@EIGH;?AA#,#(5=?@?C?BC?CAAC>AACC??A<
+@SRR9130495.11 D00236:723:HG32CBCX2:1:1108:4089:1977/1
+CATTCCAACCAGCCGCTTAAAGTTTCTAAAAGAAGCTGGTCATGGAACCCAGAAGGAGGAGATACCTGAGGAGGAATTAGCAGAGGATGTTGAAGAGATTG
++
+CCCFFFDFHHHHHJIJJJJIIJJJJJJJJJJJIIGJJJIGHGIJJIJJIJJIIFHGHIJJGHEHHFCEFFDEDDBDDDDDDDDDDDBACDDDDDDDDDDDD
+@SRR9130495.12 D00236:723:HG32CBCX2:1:1108:6197:1936/1
+NCTTAAAGGCAAGGTGCTCGGCTTCCGCTATCAAGACCTCCGACAGAAAATCCGGCCTGNGGCTAAAGANCNNNNNNNNANNNNNNNNCNNGGNNCNNGGC
++
+#1BDFDEFGHHHHIJJJJJJIJJJJJJJJJJIJJIGIJJIJJJIJJJJHIJJHHHFFDC#,;?BBDDDD#,########+########+##++##+##++8
+@SRR9130495.13 D00236:723:HG32CBCX2:1:1108:6415:1939/1
+NTGTGTATGGGGATGAGGAAGGATATTAATATGTTCTATTTGAGATTTAGGGATTACATTTGTTTTTGCNCNCNNNNNTTTTNTCNTCATTTGNNGTNAAT
++
+#1:ADDDFHGGHFGGBHIGGIIJJEIIIJJIJIJJJFGJIIHGHGDGHJGHIHIIIIJJIIHFHIIJJJ#-#-#####,,;?#,;#,8?DDEE##,+#+2<
+@SRR9130495.14 D00236:723:HG32CBCX2:1:1108:6361:1952/1
+TCAGATCTTATTTTAATAGTTGACTTTACCTCTTCTTTGACTTCCTCTTCCTCGGTCTCAGTAGATATAGATGGTACCTTGGGCTTATGCCATGAGATCTG
++
+CCCFFFFFHHHHDHIIIIJJJJJJJJJJHIIIJJJJJJJIHJHJII>GHIEGHIIIIJJJIJJIHHIJJJIJIGHIJJGJJHFHHFFDCFFEDCEDCCDEC
+@SRR9130495.15 D00236:723:HG32CBCX2:1:1108:6263:1960/1
+CAATATCTGACTGAATGGGCCCATTTTCATAATATTCTGAAACTGTTCATACATGTCTCGCAATGTAAACTGACCTGAAATGCAATACAAAAAAATTCAGA
++
+CCCFFFFFHHGHGGGIIIIJJIJIJJIIIIIIIIEIHGGIEGGHGIJJIJJJCECGHIIIJJJJJIFGHIIHGIIJJHHGEFHDFFFFFCCCDDBBCCDCA
+@SRR9130495.16 D00236:723:HG32CBCX2:1:1108:6338:1988/1
+AGACACTAAAATGCCATGTATGAGACTACATAGACATACCAATTTACAACACAAACACATGAAATATACATGAGAAAACATTAACTTACTTCCAGTTGGGA
++
+C@CFFDDDHGHHHIIIIHJJIIHIHGIJJJJJIJJJIJIIHEHIIJJJJJJIJJIIIIIJJDHIJIJGIJIJJIJJHHGGHFFFFFFFEEEDCCC@ACCBA
+@SRR9130495.17 D00236:723:HG32CBCX2:1:1108:6742:1944/1
+NGAAACACTCTTTTTCTGGAATTTGCAAGTGGAGATTTCAGCCGCTTTGTGGTCAATGGTAGAAAAGGAAATATNTNCATATAAAAACTAGACAGAATGAT
++
+#1BDFDFFHGHGHJJJJJJJJHIJHHIJIIJJIJJGIJJIJIIJJGIJIHIJJJIIJJJHIEIIJJJJIHDEFH#,#,5=ADEEEDCDDDDDDDCDD5@CD
+@SRR9130495.18 D00236:723:HG32CBCX2:1:1108:7076:1942/1
+NGTCTAAGAATGAAGTGCTTATGGTCAACATAGGCTCCCTGTCGACAGGAGGAAGAGTTAGTGCAGTCAAGGCTNANTTGGGCAAAATTGTTTNNACCAAT
++
+#1:B:BDDHHFFHIEGGIGIDEHGEEGIGHIIIFACHIGIGCFGEHIGGHHGHGH@DCGGIDEIIIIFFHHAEE#,#,5=@BBC@BCCCCCCC##,+8?BC
+@SRR9130495.19 D00236:723:HG32CBCX2:1:1108:7440:1957/1
+CACCTGATGTCCCACAGTCCTCATAGACACTAGCACTGACTGCTGGCCATCGTCTCAGCCAGATGATGTTGACCTGCTAGCTTTTCAATTAAATTATTAAA
++
++=144=DD>D4CCD?E@AECFFIIIIEI?E+??;3EBDECEIBEECDIEIIADDDDEIDCDCA;=A@CECE7ACD=(;;A@DA@A@A:ADAAAD>AADBB>
+@SRR9130495.20 D00236:723:HG32CBCX2:1:1108:7363:1977/1
+ACTCATAGAGTTGAAGATTCCCTTTCATAGAGCAGGTTTGAAACACTCTTTCTGGAGTATCTGGATGTGGACATTTGGAGCGCTTTGATGCCTACGGTGGA
++
+CCCFFDDDFHHHHJJJIJJJJHHIIHGIJIJJJIGGHGIJIJJIIIJJJJJIJIGBFDHIIJIJGIJIGGCHGGIJHIIHHHFECDECEEDCDDCBD9?B?
+@SRR9130495.21 D00236:723:HG32CBCX2:1:1108:7298:1979/1
+AACCGTCGCCAGGTACCATCCCAGAGAACTCTGTCTTCCTTACTTATAGCCAAGTTGCCGGCAGATCACAGCTGCATGCTTATCGGTCCATCCGTCATCGC
++
+BCCDDDFFGGFGFJIBBHHIJJIIHHIIIGJIIHIIJJJIIEIGHJIIJJJJIIHHGIJFGHGFDDCEECDDDDDDDDDDEDDDDDDDBDEDDD<BBDDDB
+@SRR9130495.22 D00236:723:HG32CBCX2:1:1108:7487:1988/1
+TGAGAAAGCCTTCATCACATACAGAACACTTCTAAACCACAAAAAAATTCATCTTGGAGAAAAGCCCTATAAATGCGATGTGTGTGAGAAATCTTTTAACT
++
+CCCFFDDEFHHGHJIEGGHGIJEIGHECGIIJIIIIIIGHGGEIIIJJJIGGFGGH@FECHDHCHHHFFDCEECDCDBDBDDED@ACCDDDDCDACC>CCC
+@SRR9130495.23 D00236:723:HG32CBCX2:1:1108:7307:1995/1
+TAATTTGGTATATGTCTTTTTAAAGGCATTTTTATTAGATATTTCCTTAATTTACATTTCAAATGTTATCCCCAAAGCCCCCTATAATCTACCCCTGCCTT
++
+;?7DD?;DBFHHFIA<DBEC<EHH@3AC?C@HGE@?FGAFHDBA*1?4FBCGAGHGEB99B49D<F9BF488CBD9)7@AE:/;7;@A?@@@3;=?=;;(;
+@SRR9130495.24 D00236:723:HG32CBCX2:1:1108:7539:1956/1
+TTGTTTTGACCAGGCACGGTGGCTCACGCCTGTAATCCCAGCACTTTAGATCGGAAGAGCACACGTCTGAACTCCAGTCACCACTTCGAATCTCGTATGCC
++
+?8?=BA?DFDFFB:?F@<8AFBFDFDBFF@?BBGGEGB9?FGIIF<??CFEAEFFIDFFIFFF@9BDDCC;6;65@>;A@AABBB@B?2<58+:?<<9<@:
+@SRR9130495.25 D00236:723:HG32CBCX2:1:1108:7870:1955/1
+CTATCCCGTCGGGTGACTGTTTCCTGCTTTGCAGTTATTCAGTGGCAGAGCGTGGCGCTCTAATTTCTGCTTTCCTCTTTCCTGCAGATTGTGTGCTACAT
++
+CCCFFFDFFHHFHBHGJIIIHGIIIJJIJIIIIJHIIIIEIJJIIJJJJIJIJIJDFEDDDCEEEEEEDDDDDDDDCDDDCDDDDDDDCDDDCDDDDDDDD
+@SRR9130495.26 D00236:723:HG32CBCX2:1:1108:8157:1994/1
+GAAGTGCTCTTCGTTACTACTTAAATCCCCCTGGGCATGTTTCATTATTTTACAATTTGTGCAGAACCCTATCCAAACACACATGGAGTACAAATGACTTC
++
+CCCFFDDDDHHDHHIGIIBIHHHJJJ@FGG<FEGHGDEIGIIIIIDBBFGGB@GFGGEFHGGHEC@DCEGGDEHEHDBEFEDDEE>A?@CCCCCC@CCCDD
+@SRR9130495.27 D00236:723:HG32CBCX2:1:1108:8703:1937/1
+NATAAAAAAATAACATCCTTTCCTCCTAATAGCTTAATTATTTGAAAAAAAATATTTTCNAATCACATGNANNNNNNNNTNNNNNNNNTCTTTNNTNNCCT
++
+#1=DFDDDHHHHHIIJJJJJFIJJJIGIEGIIJJJHHIJJJJJIIJIIIIIJEHEHHHA#,;??AEDDC#,########,########++8??##+##(+2
+@SRR9130495.28 D00236:723:HG32CBCX2:1:1108:8702:1991/1
+CTCAGAGATTAAAAATGAATAACGCCTGCCGGCCAATGAGCGGACTCACAGTCCCTGTTTGTTTGTAAGCTAGGTGATTTTCAATCCACAGGGCAGGCTGA
++
+@@@DFDFFGGDHFGIIBGEHJIIIBGIIIJJIIJIJIIFGGEGIJJJHGGHHHDCFFDDDEDEDDDDDCDDDCBDDACDEDEDDDDCCCCD<?BBBBDBDB
+@SRR9130495.29 D00236:723:HG32CBCX2:1:1108:8950:1937/1
+NGGTGTGCAACGGCGTGATCACAGCTCACTGCAATCTCAACCTCCCAGGCTCCTGTTATNCTCCCACCTNANNNNNNNNANNNNNNNNGACTANNGNNATG
++
+#1=DDDDFHHHFHJJJJJJJJIIGIJGIJIJIJIJIJEHDHIIJIJJIIIJJJJGHGGH#,;BBDEEDD#,########,########++8?@##+##++<
+@SRR9130495.30 D00236:723:HG32CBCX2:1:1108:9308:1960/1
+CATCTCCTCTGTGCGTTGCAGTGAGTATGGCTTTGCTGAGAAGGTGGTGGAGGGAATGTTCATTGTGGTCAACTCCATCACCATCAAGATCCACTCCAAGG
++
+CCCFFFFFHHHHHFIJJJJJJJJJJJIJIJJJJIHIIFHJJJIJIIFGIGAGIFEHECDHGIHFHHHHFFFFEDEEEEEEDDDDDDDDDDDDDDDDDDDDD
+@SRR9130495.31 D00236:723:HG32CBCX2:1:1108:9667:1990/1
+CCACAGGAAAAGAGAATCTAAAAGAAATATGGGAGAAGTGATAGCCTTGTGACAAATTCCTCCAGTGGGGAATTTAGCCAGAACTTTTACCTTTCCTATAA
++
+CCCFFDDEHHHHHJJJJJJJJJJJJJIIIGGIIGIHIIIJJJJJIJEGGHJJIJJJJJJJIJIJJGGIJHHGFFFFFFEEEEEDDDDDDDCDDDDDDDDCC
+@SRR9130495.32 D00236:723:HG32CBCX2:1:1108:9793:1965/1
+GTTGTTACATGTTCATTCTCTCTATTTGTATCTTCTTTCTCTCTCACATCTGCTCCTCTGCCTAGACACTCCTGAGGAAAACCCTTATTTCCCTACATACA
++
+@@@FFDDFHHGHDFFGIIIJGIIBHJJJJEIJIJIJIGGIIIDIJIIGHGIIIJIIHIIIJIIJDIJIJHHIIDGIFGGGIGGHHFFFDEFEDEEDEDDCD
+@SRR9130495.33 D00236:723:HG32CBCX2:1:1108:10297:1993/1
+TTCACTTTTGGAATTTTAGGCATTCTAATAGATGTATAGTGGTATCTCATTGTGGTTTTGATTTGCATTTCTTTAATGAAATTATGTTGAGCATTTTTTCA
++
+@@@F?DADFDHHFGGIGIIFHJIGIGIHGIJJJJJJBGEF?CGF>GII@GIFGFE???BFBBEHIGGIEEHIHIGGHHGIHA3?CH;?@CB@DCCEDEDD3
+@SRR9130495.34 D00236:723:HG32CBCX2:1:1108:10535:1962/1
+AATACAGAAAAGTTAAGAGCCAGCCCCAGGCGGATTGGATGAATAGGTTGCATCTCTTTCTTGCTTATATCAAATGCCTCTTGGCAGGCTCCTTGGGAATT
++
+???BD:A:<?CACFGIIIB;A@D=+22+1:)1:D:?FD)/=<F@H=FGC@AGCE7=?E>3=?B:;?;;CA;;;A3-5>5-5:(::@8/2?8?9>>3(83(+
+@SRR9130495.35 D00236:723:HG32CBCX2:1:1108:11147:1968/1
+GCTGCCTTCTCCCCTCAAGGATGCAGTGGAAGTGTCAACCTGGAGAAGATGCTACACGATGCAGGAGGTGAACTCGGCCCTCAGTAAAATCCAGCTGGTGG
++
+CCCFFFDFHHHGHJFEGIHEGHIGIIGCCGGGIIJJIJJGGGGHCGIF>DGHIIIEHHGIIJJDBGHFHFCCFFFDDCDDDDBDDDCCDEDA:CACD@CDD
+@SRR9130495.36 D00236:723:HG32CBCX2:1:1108:11124:1986/1
+GACAGGGTTTCACCATGTTAGCCAGGACGGTCTTGATCTCCTGACCTCGTGATCCGCCTGTCTCGGCCTCCCAAAGTCCTGGGATTACAGGCGTGAGCCAC
++
+CCCFFFFBFFFHGGHGHIHIIGIJFJJJIJHIIIFGHGGIIGEGHIH@@FGGIJIIGGIHIEEHEEFFDDCCCCBDDACCDCDBAACCDDDBDDDDBDDCC
+@SRR9130495.37 D00236:723:HG32CBCX2:1:1108:11773:1947/1
+TACCTGCCTCTGCCTCTCGAGTGCTGGGATGAAAGATGTGCACACCCCCACCACCACCACCACCACTGCCTGGCNCNGTTTTTGATTTCTTATTCTCCAGA
++
+CCCFFFFFHGHHHJIJIJIIEHIJJIJJIJJIHIHJJIGFIIIIJBHHGFF>HGIJIEHHHFGDEEEEEECC?B#,#,,5?<?BDCCD@@CCDCDDCCDCA
+@SRR9130495.38 D00236:723:HG32CBCX2:1:1108:12184:1941/1
+NGTGTGTATATATTACTGCTCATTAACGGTGCACGTGGTCACCCAAGAGCTCTGATAGCAAGGTACAAAGAGATNNNTGTTGTTTTCACGCCCNNTANCAC
++
+#11ABDDDHHDFHIIIIIIIIHIIHFHFHIIIIIIGGGIIIGDFFHIIIIIHIIIIIIIIIIIHGCHIIGBEEH###,,;?ACDDDDDDDDBB##,+#+28
+@SRR9130495.39 D00236:723:HG32CBCX2:1:1108:12711:1965/1
+TTCCAGAACATCCCCAAACTTTCCAAGGTTTGGTTACACTGTGAGACGTTCATCTGCGACAGTGAGAAGCTCTCCTGCCCCGTGGTGAGGGTCCTGGCTCC
++
+@@@DDFFDHFHHFIIJJJJIJJHGEHJJFIHHEHGHHHIIIJIIHJJIHIJDGIIIIIJJJJJHHHGHEFFFFFEEEEDDDD?BDBBCDDDDDDACCDDDB
+@SRR9130495.40 D00236:723:HG32CBCX2:1:1108:13153:1937/1
+NGTGTACTTGACTAACTCCAAAGTTGTCAGTCGAAAGTGACTTTCCTGTCACAGATCATNCGGTGTTTGNTNNNNNNNNANNNNNNNNTNNAANNTNNCAG
++
+#1:BDD?DHHHHHIGIIFCE;4CHHGGI>@HF1CGBGHC<DHIGHIIGG>DD<BH@GGI#-71CFHIGH#-########,########,##,,##+##++2
+@SRR9130495.41 D00236:723:HG32CBCX2:1:1108:13100:1949/1
+CTAAAACATCGAGCTTCAAATGTCTTCCTAGTATACCGCACGAATGTTTCTTTTACCATATTTTCTGGAGTGTTNGNTTAGTTTTTCCTCAAAGAGGTGTA
++
+@@@FFEDDHHHFHJJIJJGHJIGBFHHIHJIGIJEGJJJJFIIIJJGEIHHHIIIHIJJJJJIFHIHHHHFFDD#,#,5=?BDCCBCCCDDDCDDDBCACC
+@SRR9130495.42 D00236:723:HG32CBCX2:1:1108:13438:1959/1
+CTTCCGATTCCATTCGATGATGATGGCATTCGATTCCTTTCAATCATTCCCTTTGATTCCATTCAAAGGTGATTTCATTCAAGTCCATTCGATAATTGCAT
++
+CCCFFDFFHGHHHIJJJJIIJJJIGGHEEGIIIIIIIFGJJIIJIJJIJIIJJJJIJJJIJJJIIGIHGIJGIEIJGIJIIJIHGIFEHFHHHFDBFFFCC
+@SRR9130495.43 D00236:723:HG32CBCX2:1:1108:13715:1971/1
+TTTTGCTGCAAACCTGTCGATATCAACATTTCTGCTTCATGCTTCAGGTGGGTTTTCTCAGATGTATGCCTGTGTGTGCGACTGGCTGGGCTTTTCATACA
++
+CCCFFFEDDHHHHIGIGHJIIGGIHIJHEHIIJJJJJIFIJIGIIIJIHHIJIJJIJJIHHFGIIIIGIJHHHHEEFFFFACBDDDDDDBDDBDDDDEEDC
+@SRR9130495.44 D00236:723:HG32CBCX2:1:1108:13659:1977/1
+GTATACAATATATGGTTTGTGAACTTTGATATTTCATGTAGAGTATAAAATATATATTTGGGGTACTTTGATATTTTATGTACAGTATATAATCTATGTTT
++
+CCCFFFFFHHHGHJJHIIIJJJIIJJJJJJJJJJJJIJHJJJIJJJJJJIJJJJJJHIJJJJIGHJJJJJIJJGHIJJJJJIJIJHHHHHHGHFDFFFFFE
+@SRR9130495.45 D00236:723:HG32CBCX2:1:1108:13735:1988/1
+TGGCAAGGGCTGCCCTCGTCCACATCCTGGGGTGTGTTAATGGGACTGTTGCTGTCTAATGGGAGTGCTTTGCCTGAGGGAAGCCTGCATCTCACATCCAC
++
+?@@DDBD?FD?DDHEG=E@FBHD?<FH@FGHG:@DB(9==BFE2C@>FF7=DEG.?AAC?3@EED;6@;>(-;@AC?31(,5?<?C8?CCA@>(4::A>AC
+@SRR9130495.46 D00236:723:HG32CBCX2:1:1108:14226:1948/1
+AACCTGCACCCAGAATGGCAGGAGGTCCTGGTGGCCCAGGGGGTCCTGGTGGTCCAGGAACACCAGGTCTCCCANANCCAGGTGGCCCAGGCAGGCCTGGA
++
+??1D1BDDHFHHBBHGGGAFG)AF1:?CEGD@BGAFDGIGGB'5;CE77?=???>>C<A@??C=9<<CCC:>C3#+#++228>>28((2(<??<95@AB<1
+@SRR9130495.47 D00236:723:HG32CBCX2:1:1108:14223:1987/1
+GCTTTCCTGGGAGTGAGCTCCCTGGCGGCCGCGGGGAGCTCAGGGCAGGCTCAGGCATCTCCAAGGCGGCCCTGGAGGTGATAAAACTTGAGAAATAACTA
++
+CCCFF?DDHFBHGHGGIIGGIGIEGFGIGEIIIIFBDBD?CCDDBDDDBDDDCC?CDCDDDDDDDDD@BBDBBBD<AB8ACCCCCDD>>ACC?CCDDCCD@
+@SRR9130495.48 D00236:723:HG32CBCX2:1:1108:15049:1993/1
+TGACCAAGAACTCACAGAGATCCCCCCCCCCAGGGCTAAGATTAAAGGCATGTGCCACTGCCACTGGATAGATATTATCTTTTATTTTACCTGACTGGTTG
++
+@CCFFDDDHDFHGJJJJIJGIHHHIIJJIJFE=(5;?@>@A@;@C>CAB=@<:@C@CA:>CC3:>CB<@@?344>>@@A>CDC>ACDD:>4>>>ACD?CC(
+@SRR9130495.49 D00236:723:HG32CBCX2:1:1108:15487:1951/1
+ACGGAGGGTGGGGCTGGGTGATTGTGGTTGTCTCCTTCTTCACCCAGTTCCTCTCTTACGGATCCCCGTTAGCTNTNGGGGTCTTGTATGTAGAATGGCTG
++
+BCCFD@DFDFHHGDGIIICGHIIJJIJGHIIJIIJJJIJIJIJEHIGHHHHHHHFFFFFFDDCDDCD@DDDDD:#+#+2<@8<CDCCDEDDBCCDCCDDCB
+@SRR9130495.50 D00236:723:HG32CBCX2:1:1108:15659:1969/1
+AAGTGCAGCACATGTGAAAAGTCCTTCAGCCACAAGACCAACCTGAAGTCTCATGAGATGATTCACACAGGAGAAATGCCTTATGTCTGTTCCCTATGTAG
++
+?;=BDDDEDDFFFIIIIIIIIIGGHIHHBHHIIGEGIGGEHGIII@HDHI>GHIIIEHGACFHIIGGIBHIIHHC??BDC@BBCECDCE63>@@CACCDD@
+@SRR9130495.51 D00236:723:HG32CBCX2:1:1108:15923:1957/1
+CCGCAACTGCCATGGAGCCACAGCCTGGTCCGTAATAGATGCAAAGCTTCTCAATAGTCAGGGGCGTGGTTTCGCGCAGCTTGGAGGCCAGCAACAGGCAG
++
+CCCFFFFFHFHHHIIFIIIGIIFIIGJIIJJIFHGHIIIIIJIIFIJIIIJJJJJJJGGIGJFFH@?BBBDBCDDDDDDDDDDDDDDDDDDDDDDDDDDD?
+@SRR9130495.52 D00236:723:HG32CBCX2:1:1108:15793:1968/1
+GTTTTTCCACAGACCTCTGATCTCTTACATTCGAAAGTTCTACTACTATGATCCTCAGGAAGAGGTGTACCTGTCCCTAAAGGAAGCGCAGCTCATTTCCA
++
+BB@FFFFFFFHGDGFHJJJJIFIIGGG@FIIIGIBGGDHIIIJCHIIJJDHIIJJJIIIGIIJJFHHIJCHGDHIIHHHHHFFFFFDDDDDDCDDDDEDDE
+@SRR9130495.53 D00236:723:HG32CBCX2:1:1108:16082:1968/1
+GAAACTTGTTTGTGACGTGTGTATTCAACTAACAGAGTTGAACCTTTCTTTTTACAGAGCAGCTTTGAAACACGCTTTTTGTAGAATCAGATCGGAAGAGC
++
+@<@ADDDECBFFHIFEGDG;EEHHB@<CHHHGHCFII9CDCG@@DGHGH>FHGHIIGGEHGGHGGEGEGICGCEFFDB@D>AE<A@>>ADC@CBB<B@??A
+@SRR9130495.54 D00236:723:HG32CBCX2:1:1108:16094:1977/1
+AGACAGTTTGAAAGAAATAATTGATGTGATAAGCTTGGAGTTAGTAGTGGATGCAAGCTGTCAGTTCAAGTAATCTCTCTATTACTGAAGGTTCCCATCAT
++
+@C@BFFFFHHFHDDEFGEHGIGH>FGIIJJJJIHHIJJGH?DGGHCFHHIJJEEIIJAHIJJFG=FGGGIFHHIIDHGEHIHHHHGHGEB;?CDCECEEDD
+@SRR9130495.55 D00236:723:HG32CBCX2:1:1108:16048:2000/1
+AGGACAGGAAGGACGCTTTGAGATATGATTTCACAGGCGACAGTGAGAGAAAACCAATGTCTTTAATGCATTTCTCTGCAGCATGTGACAAACTTTCAACA
++
+CCCFFFFDFHGHHIIJJJJIFGGIJJIIIIJIJIHJIIJIHGIJJIJGGIIJIJJHHHHEDCDFFFEEEDDEDEEDDDDDDDDDDCDEDDCDDDDDDCCD@
+@SRR9130495.56 D00236:723:HG32CBCX2:1:1108:16580:1970/1
+GCCTGTACTCCCAGCTACTTGGGAGGCTGAGACAGGAGAATCACTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGACCGGGCTATTGCACTAGATCG
++
+@@@FFD?DBFFHHIIEHCIJIFIJHEDCH@GGEBFHHIJJIIIIIJJJJJIFHFHF@G-6@AAEDFFF>AEC@@A?;=?BCD6/<@>BAAC>:@C:CDDA?
+@SRR9130495.57 D00236:723:HG32CBCX2:1:1108:16594:1971/1
+TCCTCTGACTTTGACACTAGTGTTGACCTTGCATGAGGAGATGTTCTCCATTTGGACTAACCTGATGTACACAGACGTTACACTTATCACAGAATACCATA
++
+CCCFFDDFFHFHFHIJIJJIHIIIJJJJJIJJJJIIIIHIGIIJJJIGIIJJIIJEHIIJIJJJIGIJJJEIHJJIIHHEFFFFFFCCEEEEDCDDDDDDC
+@SRR9130495.58 D00236:723:HG32CBCX2:1:1108:16808:1998/1
+ACCAATTTTCCCCTCCCCTTCCTCCCTCCCTCCCAGCCCCCTTCCTCTCTCTACCTCCTGTTATTGTTTTGTTCCTTGTTCTATGTAGGATTGAAGCATCT
++
+@@@FFDDFHDFHGIJJJJIIGGDFHI>DGC;DHI9??FHIJIIHG<C=8B;=CFE@EGEE@A=?EHHFFF<BAA@@AECDA>>>3>;ACCCC9:@>@:>AA
+@SRR9130495.59 D00236:723:HG32CBCX2:1:1108:17428:1967/1
+TGCATGGTGCTGAAAGCTTTGTTGCAGCTTTTCTTGGGATTGCTTAGCTGCTCCGGGTCGATCCACTTGCAGATGAGCTCTTGCTTGATGCACTGCTGCCG
++
+?<<??BDDD4:<D<DE+<C<CFEE<<+2A<?E*@E9*)?DD)::*:?4B*BDDDDIAD/@A(6??DA@;3?;;6(((.-(55(;35:9>A3>A>>AAAA?3
+@SRR9130495.60 D00236:723:HG32CBCX2:1:1108:17508:1988/1
+TTGTTCAGAAAAAAGTATCTTGAAACCAAAAGAACTGGGATCTTGTTAAATGCAGATTCTGTTCATTAGGTATAGGTATGCAGTCTTACAAAATGAGGTAG
++
+CCCFFEFFHHHHHJJJJJJJJJJJJJJJJJGIJJJJJJJIIJJJJJJJJIJJIJJJJJJJJJJJIJJIIIEHHBHGHHEFFFFFEEEEDEEDDCDCDDCDC
+@SRR9130495.61 D00236:723:HG32CBCX2:1:1108:18425:1951/1
+CCACTTAATAAATCACCTATCAAGTTGAATTATTTGTGCAAAGGCACTAGGCTGAATAGAGACCACTCAGTAGCNTNTTTTTAATCTTGCTAAGAAAGAAT
++
+CCCFFDDFHFHHGJIIJJJJJJHGHEHHHIIJIJJIJGJIHIJHEFDHGHIFIJJGHIJJJFIGGIHIIIJIII#-#-5@DFFEEEDEEEDEDDACDCCBC
+@SRR9130495.62 D00236:723:HG32CBCX2:1:1108:18468:1964/1
+CTATTGACTTTTATTAGAAAGGGTCTTGTTGCATAGGTAGGTCTTTAACAACCATCTCTTAAAGGGCTGGGATTGCCAGAGTAGGCCAACACGCCCAGCTA
++
+CCCFFFFFGGHHGIGIJIJJIIIJJJJIJJIJJJJIIJDGEHGIIJJJIJJJHIJJIGFHGIJGEGIJJJIIHHHHHHFFFFFEDEEDDDDDDDBDDBBD@
+@SRR9130495.63 D00236:723:HG32CBCX2:1:1108:18615:1941/1
+NAGCCGAGAGGCGCCGGCTCACCTGCCTGGGTCCCGGCCTTTCTCCTGCAGTGCCAGGGATTCACCTGANGNCNNNNNNTCTNCTAGGCAAGCNNATNCTT
++
+#1:DDFDDHHHHHIIJIIFGJJIEFHHIHHIIIJJIEHFFEEEEEEE<CDCDDCCCDBDDCDDDDDDDC#+#+######++8#+8??<CDDBD##+2#+2<
+@SRR9130495.64 D00236:723:HG32CBCX2:1:1108:18957:1948/1
+ATAATGAAGAAATTTTGGACCTTCTATGTTCATCTCGTGAGAAAGCTACTCAAATAAATATCCGGGAGGACCCTNANGAAGGCATAAAGGTGTGTTTTCCC
++
+CCCFFFDAHFFGHJIIJBBGGIJJIJIIJIJJJIF@GGGHIIJGEEGHI@GIGGIEIIIIJGJIIJHEEHFEBC#,#,5?BDDDDDDDDCCCCDACCDDCC
+@SRR9130495.65 D00236:723:HG32CBCX2:1:1108:18983:1999/1
+CATCATCCTGAGTAAGGTAACCCAATCACAAAAGAACTCACATGATATCTACTCACTGATAAGTGGATATTAGCCCAGAAACTTAGAATACCCAAGGTACA
++
+CCCFFFFFHHHHHIJJJHFIJJJJJJIJJIGJJJHIIIJJIJJIIJJJJJJJJJJJJJJJJIJIJJIJJJJIJJJJJHHHHFFFFDFEEEEEE@ADBDDDD
+@SRR9130495.66 D00236:723:HG32CBCX2:1:1108:19168:1981/1
+TAACCGGTGAAGTGTCAAAGAGGCAGGAGTGGAGGGCTGCGGGGGTGACAGGGTGTGGTCTGCCTGGAGCGGCGACGTGGGAGAGCGGGACAGAGGCCTGG
++
+CCCFFDFDHHHHHIJJJJJIIJJJJJIGEHGHHIJIJIJJJIIDDDDDDDDDDDDDDDCDDDCCDDDDDDDDDDDDD@BBDDDDDDDDDDDDDDDDDDDDD
+@SRR9130495.67 D00236:723:HG32CBCX2:1:1108:19555:1966/1
+ATCACATCTCCATTCAATTCACCTATTTGCCCTGTGCAGAAGACAGACAGATCTTGGAGAATGATAGTGGATTATTATAAGCTTAGCTAAGTGGTGACTCC
++
+CC@FFEFFHHFFHIIIJJJIJIJIIJIJIIIJIGHGEGGGIIFGIJGIJIIIIIJJFHIJIJJIIJICGGIJJJJIJJIHHGGHFFFFFFBAECECACDDA
+@SRR9130495.68 D00236:723:HG32CBCX2:1:1108:19764:1940/1
+NCAATTTTGGAAAAGTGAGTGAATTAAAATTCCAGGAAGAAGTTTAGCAAAATTGTAGANCGGAAGAGCNCNCNNNNNNANNNNANNNACCACNNCNNATC
++
+#1=DDDFFGGHHHJJGFGIJJIIJIJJJIJJIJIIJJIJIIGGGIJJJIIIIHHGIFHI#-<CHGIJJJ#-#-######,####,###,,8?B##+##+++
+@SRR9130495.69 D00236:723:HG32CBCX2:1:1108:19805:1986/1
+CGCAGTGCCCCGTCCTGATTGATCGCATCGCTGGGCTCAGATGACTGTAAAATGAATAGATGAAATCCTTGCTTCTGGAAGATTTTCTTGGGCATCTCCGG
++
+CCCFFFFFHHHHHJJJJJJIJJJJJJJJJJJJJIJJJHIIHHIIIJJJJJJJJIGGGHIJHHEHHGHFFFFFFEEEEEEDDDCDDDEDDDCDDDDDDDDDD
+@SRR9130495.70 D00236:723:HG32CBCX2:1:1108:20271:1962/1
+TGATGATTCCATTCCATTCCATTCAATGATTCCATTCGATTCCGTTTGATGATGATTTCATTCGAGTCCATTTGATGATTCCATTTGATTCCATTCGATGA
++
+@<<ADDDDDFHFFFFHEFHEGIIJIICHEGIJJCHHCBBHHJJIHECG@GHIIICIJJEGIGGEGIIIGHIIIIGHFCHHGDFGEGIIEEHIGHIDGGIGF
+@SRR9130495.71 D00236:723:HG32CBCX2:1:1108:21157:1952/1
+CCCAGCACCAAGCGTCCATCTGACTGCTCATCGGCGGTCTAGGGAGTAAGCCGTCTGGAGTTCTCTAACCTGATNCNGTTTCCACTTCCACAGGTGACAGA
++
+@@@DDD?>?DFF<GF;CA?FHDHAH?:E<DF4D@@DF-''=@CAFA?;;B77=@B?B@B<55>;5:AAB9>29(#+#++8++4>>:@>AA:@1<@@A(:4?
+@SRR9130495.72 D00236:723:HG32CBCX2:1:1108:1440:2047/1
+GCTGGTGCAGGACACCAGAATCCGCTCGATCATGCTCCCTAGAGAGGAGGGGCACAGTGAGTACACATAAGCACATGTACACACACACCCAGGACCCAAAG
++
+CCCFFFDEHHGHHHIIIIIIIIJJIJJJGEGHIJIJJJJIIJGHIIJJJIDFEDFFFFEEEEDEDDDDDDDDDDDDDEEEEDDDDDDDDDDDDDDDDDDDA
+@SRR9130495.73 D00236:723:HG32CBCX2:1:1108:1468:2080/1
+ACTGTCTTTTTTTTAAAACAGGTGATTGCCCGTTGATTGTTCAGTTTGCTGCTAATGATGCAAGACTTTTATCTGATGCTGCCCTGCTAGTCTGTCCCTAT
++
+CCCFFDDEHFFDHIEIIJHGCGFHCIIHIIIHH@FGGIHIGHIJJIJGIIIJBHIGEIHGHHGGHFFFFFFEEEEDEDDDDDDDDDDDCDDDEDDDDDDDD
+@SRR9130495.74 D00236:723:HG32CBCX2:1:1108:1333:2084/1
+ATGAGCACACAAGGGATGATCAGATTGATGGTGTAGAAGAGTGGCTTGCGCTTGATGATGAAGTCATAGGTCACGTCCACATAGCTGGGGTCCTGTGGGTT
++
+CCCFFFFFHHHHHJIJHDIIHHHIIJIIJJJJJIJJIIJIJJJIBDGIJJJJIJJJJGIIIJIAHEEHEFFFFF>EDCDDDDDCDDCDDDDDDDDDCDDDD
+@SRR9130495.75 D00236:723:HG32CBCX2:1:1108:1447:2137/1
+TCCACTTGTACAAAAAATTACAAAAATTAGCTGGGCATGGTGGCACACACCTGTAGTCCCAGCTACTCGGGAGGCTGAAGTGGCAGGATCACTTGAGGCAG
++
+CCCFFEFFHFHGHJJJJIJJJJIIDIEHJIIJJJIGJJJHGJIIDHIDGIJIJJIGHIJJJJJHHHFEEBDCDBBDDDDDDDDDDDDDDDDDDDDDCDDD@
+@SRR9130495.76 D00236:723:HG32CBCX2:1:1108:1499:2151/1
+GAGAAAAAGCATCCCTTTAATAAGGCCGCCCCGGTTCCAAATCAATCCTGGCATTGCAGGAGGCAAGGGGGAAACACAGCCACGAAATTGGATTAGCTCTT
++
+CCCFFFFFGGHHHJIIJHIEIJJIIIIJIIGJJIHJIJJIGIJJJIIJJHHHHHFFFFFFDCDBDDDDDDDDDDDCDDDBDBDDBBDDDDDCDDDDCDDCD
+@SRR9130495.77 D00236:723:HG32CBCX2:1:1108:1280:2166/1
+GCCTTCTTCCCAGCAGCAATATGGCTCTTTCTTCAGCTCTTATCAGTCACATCCATCAACGAGTGGCTTTTAAAAGGGTATGTTTAAACCTTTTGACGGGA
++
+CCCFFDEFHHHGGJIJJIJIJEIJJJJJIFGIIIIIIIJIIGIJJGIIBHIJJJJIJIEH>CG;CHCHGHICHFFFFFFDDC;@CCEEDDCDDCCDDDDDB
+@SRR9130495.78 D00236:723:HG32CBCX2:1:1108:1458:2216/1
+TTTCTTTCCACACATCCCACCTAACACCCAAACTAAGCACTCAGTGCTTGGAATCTCCCCACCCATTCCCTCACCCCTGCTCTTCCATCATTTCCTCCAGC
++
+CCCFFFFFHHHHHIDHIIJJJJHIIJFHIJIJIGIJHGIIIIGJEHIGIIJCGEEHJJJJJJJDHEHHGFFFFFDCDDDDDDDDDDDECCDDEEEDDDDDD
+@SRR9130495.79 D00236:723:HG32CBCX2:1:1108:1634:2001/1
+TGTGCATTTCTCATTTTTCACGATTTTCAGTGATTTCGTCATTTTTCAAGTCGTCAAGTGGATGTTTATGATTTTCCATGATTTTCAGTTTTCTTGCCATA
++
+CCCFFFFFHHHHGJJJJJJJJIJHGIJJJJIIIIJJIGIIJJJIJJJIIFIIJJJJJIJJJIJIIIIIIJIJGJJJJFHHGGHGFFFFCEFFDEEDEEDDD
+@SRR9130495.80 D00236:723:HG32CBCX2:1:1108:1566:2120/1
+GGACGAAGTAAGGGAGGAGCAACTGACAACATTCATCTTGTCTGTCTCCTCCACGTCCCGAGGTACAAGGCGGATGTCATTCTTACTAATTTTTTTCTTCT
++
+CCCFFFFFHHHHHIIJJJJIJJJIJJJJJJJIFIJJJIJIJIJIIJJIJIJJJJIJJIIJHHFFEEEEEDDDDDDDCDEDEDEEDDDEDDEECDDDDDDDD
+@SRR9130495.81 D00236:723:HG32CBCX2:1:1108:1863:2047/1
+AAATTCGGACCCCTTGGGTGGAATATTCCTTACGAATTCAATGAGACAGATCTAAGAATCAGTGTGCAGCAACTCCACATGTTCCTGGACCAGTATGAGGT
++
+@BCFFFFFHHFHHHIJIJGIIIJIJJJJIIJJIIIIJJJJGIJJJIJJIEGIIGIJIJJJEGHHHGEEHFFFFDEEEDDDDEEEDDDDDDDBBCDDCCCCC
+@SRR9130495.82 D00236:723:HG32CBCX2:1:1108:1844:2145/1
+TAACTCTCTGCCTGCGATGTCCCTACCTTCCAGAATGGTGCCATGACAACGGTGTCAACTACAAGATCGGAGAGAAGTGGGATCGGCAGGGAGAAAATGGC
++
+@CCFFFFFHHGHHJJJJJJJIJJJJJIJIIIHIIIJIIJJJJIJIIJIJJJJJJJJJIJJIIJEHHGHHFDFDDDDDCDCDDDDDDDDDDD?>BDDDDDDD
+@SRR9130495.83 D00236:723:HG32CBCX2:1:1108:1772:2188/1
+GAGGTAGGGGTGTGTGTGAATGGGTGAGTGTGTGCCTATGCTTGTATGCCATATGAGAGAAAATGCAGCATTTAAAATCAGTGGTTAACGGCCAGCACAGT
++
+B@BFDFDDHHDDHHGIGIJIJGIJ:CFHHIGGIJJIEHGIIIJIIIFHGIJBHIJJJJJJCHHIHHHHHGFDFFFFEEEECEEDDDDDDDDDDBDDDDDCA
+@SRR9130495.84 D00236:723:HG32CBCX2:1:1108:2103:2085/1
+TACAAATGTGCCAGGCACTCTTCTAAGTCCTCACATGCATGAAGTTATACAACTCTACAACAAACCTAGGAATATAAACTGAGGGCAGGGACCCCCAGCAA
++
+CCCFFFFFHHHHHJIJIJJJJJJJJJJJJIJJJJJJIJJJIJJJFHIJJJJIIJJJJJIJIIHIICHHIJJJIIIJJHHHFHHFDDDDDBDDDDDBDDDDD
+@SRR9130495.85 D00236:723:HG32CBCX2:1:1108:2067:2091/1
+ACCAGCCCTGCTGCCACCCAGCCCACGTCCCGCGCGCCACCCATGCTGCTGCCTCGGAGCTGCAGGGAGCCGGGGAGCCAGGGCCACACGCAGGTGCAGCT
++
+?@@D?A:BF8DDFFFFFFFFAECBF@GFECAEFIIIIIIFBE?DBBD;@CCCCBBBBBB@B::AABBBBBB7>BBB>@BB?B>B<BBBB@BBBBBBBBA@B
+@SRR9130495.86 D00236:723:HG32CBCX2:1:1108:2104:2209/1
+GGTTGTGAATACTGCAGTCTTTGCCTGTCCAGTCTGGCTGACAGATACACTTCCCCTCGTTGCTGCAAACCTACAGGTAGGCGAGGCCAGCATGGATAAGC
++
+@<@DDDFDHDHDFGHEGHIGGGIIHIIBGHHIHIIIIDGGGFEHIIIIIIIIIIIIGGGGFHGEAEDHIHG@EHFFF@C@1>>BB?/?A?BCCCBDDDD>@
+@SRR9130495.87 D00236:723:HG32CBCX2:1:1108:2387:2038/1
+GGCTAACCACTGCCTTGTCAAGTTGTGTAGAGTGAGATTCAGGGGTGTTGAAGTAATGTCCTTGTTACTTGCTGTAGGGCATCTGTTTTCTGTGTATCCCA
++
+CCCFFDDDDHGHGJEIGHHIJIHGGIIHGIIIIIEGBEHGGHIGGAFHIJJJJJJJJIDGHIIGIJJJIIHGFHEHFDFEDCEECDCDDACCCAACDFCCC
+@SRR9130495.88 D00236:723:HG32CBCX2:1:1108:2285:2075/1
+CTGAAAGCTGAGCGTGAGCGTGGTATCACTATTGACATCTCCCTGTGGAAATTCGAGACCAGCAAATACTATGTGACCATCATTGATGCCCCAGGACACAG
++
+?;@DDBDDDFFD>ACGED@D8@):E*::??FFC@<BDGE99?F?B?F;?CCBF>;FEF>E;CC=CC=@DDD>?;>A>A>A;AB3;A(;@:??<?89<???2
+@SRR9130495.89 D00236:723:HG32CBCX2:1:1108:2395:2081/1
+CAGACCAAGGAGAGCAAATGCTTAAGGTACCAATACCTGGTTAATTCCAAAACAATACTTACTTTAGGGTCCGAGCTCTTGAACTTTAACCTTTCCACCAA
++
+CCCFFFFFGGHFHJEIIJJJJJJIJJIJJJJJJIJJJJHIIIJJJJIJJJJJJJIJJJJJJJIJJJJJJJJIGGFFDEDCEEDDDDDDDDDDDDDDDDDDB
+@SRR9130495.90 D00236:723:HG32CBCX2:1:1108:2350:2145/1
+GGAGCTCATGGAGGAAGAACTGTATGTATCTCTGGGGAATGTACTTCCTACAGCTGACATTGCCCAGTTTAAGCAGGTGTCAAGTCTGTGGCTGGCAAGAT
++
+CCCFFFFFHHHHHIJHIGIIJIHHIJJHIJIFIJJJJGGIJHGIFJIGIHIIJJIJIJHIFHGGFIJJIJJJHJGGHHHFEFFFFEDDEEEDDBDDDD?CC
+@SRR9130495.91 D00236:723:HG32CBCX2:1:1108:2261:2146/1
+GACGATGATCTTGACTTCCCTCTGCCCGACATCCGATTAGAAGAGGGGGCCATGGAAGATGAAGAGCTGACCAACCTGAACTGGCTGCATGAGAGCAAGAA
++
+CCCFFFFFHHHGHIIJI?FHHHGJJJJJGIIJJJJIJIHHHIJJIFGIIHFDFFEEEEACDDDDDBDDDDDDDDDDDDCCDDCDD@BDDDDDDDDDDDDDD
+@SRR9130495.92 D00236:723:HG32CBCX2:1:1108:2270:2221/1
+GTTACATCATCATCATCTATCTATTGAGCCTTAACTCCCTACTCAGAGAAGAGATTTTAGTCCATATCCGGCAGCCCGAGGGTACAGCGCTGAACCACTTC
++
+<;?BD?>DFBCB4<<AEAEHE@FHB9FCGHBHG?HE9E3?CDHD<C3B@BDEII<9?:?FBFAGB:<C=@8@;:C;(59<@B8>CCD@=BB@-(4812>>>
+@SRR9130495.93 D00236:723:HG32CBCX2:1:1108:2748:2098/1
+CATCATCTTTTTTTTTTTTTTCTCCTGAAAACTGTCTAGTAGTTTGATATATTTTGTCCGAGGTTATTTCAAGTGTTTTTTTTTTTTTTTTTAAAACGGTG
++
+@@@DDDDDHHHHHIIFEHIIH8))7)7CEF9).)7;;>B@>9BD;;(6(55>DDDCBCC@/8-084@CC>C(((+4>?CBBBBBBBBBBB>&23:A(5?((
+@SRR9130495.94 D00236:723:HG32CBCX2:1:1108:2733:2156/1
+GACTGAGAAGAACAGAAAGGGAGAGAGAGGCCAATGGAAATACATGAGAAGGGAGAGAGGGAGAGAGAGGGAGGGAGGGAGGGAAGGAGGGGGAGAGGGAG
++
+CCCFFFEFGHHHHJJGIIIJJHIIHHIIJJJJJIJIIHGJJJGIJJJJJJJJJHGGHHIHHHFDFCDCDDD>BDDBDDDDDDD>BDD?BDDDDBDBDBD<B
+@SRR9130495.95 D00236:723:HG32CBCX2:1:1108:2665:2186/1
+AAGGAAGAAACTCTGGATACATCTGAACATCTGAAGGAACAAACTCCAGACACGCCATCTTTAAGAACTGTAACACTCAGATCGGAAGAGCACACGTCTGA
++
+@@@DADA?DAFHHHIJBHGIIEHJIFJJIJJIJIJJIIIJJJIGIIGIJJJGIIGIIJJJIGJIIIJIJHHHHHHFEFFDFE3;>@D?ABD@BD?BBDDDC
+@SRR9130495.96 D00236:723:HG32CBCX2:1:1108:2818:2076/1
+ACACTTCATGGCAACCTGGCTTAGATTCTTCAAAATTTCTGATCCTATACCAAAGCCTCTGTAATCACTCATCACGAAGAAGTCTTCAAGATACAGTAACT
++
+CCCFFFDDHGHHHJJJJIIJIIHIJHGCHIFEGGJJJJIJIGIIJJJIIJCEHIIIIJIBGHGGIIJIIBFGGGGHHGHFFFFDEEDECEDDDDCD>CCDE
+@SRR9130495.97 D00236:723:HG32CBCX2:1:1108:2848:2112/1
+AACCTCTTCTCTTTGTCTTTCTCTTTATCCTTCTCCCTCTTGCCAGGACTGGACTCGCTGGTGATGGTGACGACGCTGGTGGGTAAGGTCTGCGCCCGACT
++
+@@BFFFFEHGHHGIJDEHIJIIIIIIJIFHIIIJEIDHIIIIJJIIIGIEIIJJIIIJFEHFHIIIGIIJIFBEDDBD>=?BB@CACCCAACDDBDBB5<B
+@SRR9130495.98 D00236:723:HG32CBCX2:1:1108:2918:2118/1
+CCACATCCCCAACCCTGAGCCTTCCCACTCCATCATCTCTAGATCCAGTGGTGCCTGGTGAGGAACAACCACTCCCAGACATGCCCTCAGGAGCAAGCCTT
++
+?@@BDDBDHHDBFDAEGBECFIBGHEH@G@CGFGHGGIEEHGAGGCHAFGGFEGGGHIIIGHHIIDEEE?7?C>;6@;ACBCCCC?@AA>C>?<<<9<?CC
+@SRR9130495.99 D00236:723:HG32CBCX2:1:1108:3133:2096/1
+GGCACTTGGCAGTAATGTGACACACACAATAGAGCACAATCAACAGGAGAGCCATAGGAGAAGCCCCCTTACCCGGCCCCTTTACCTAGGAACATGGCCAT
++
+@C@DBBDBFHHFHIFCGIG<@9FDEHGGHGEGGIBHGD)?BF>)?FHFCAG=GFFG>FGGEGHIEEBEDEFC>C@::=BB@BCACCC@CA3:(8@C<8?CC
+@SRR9130495.100 D00236:723:HG32CBCX2:1:1108:3014:2117/1
+CCCTCCTGAAAAGGTCCAGCTCCAAAGCCTGACCCGTAGCTGCAGAGAAGAAAGCTTTTCCTCTAAAGGCTGAGGAAAAGATGAAAAATCACTGCTAGAAC
++
+CCCFFFFFHHHHGIJIJJJJJJJJJJJJJJJIJJJIJJIJJJJIJGIDHHIIIJJIJJJJJIJJJHHHHHFFFFDEEEEDDDDDDDDDDDDDDDDDDDDDD
+@SRR9130495.101 D00236:723:HG32CBCX2:1:1108:3316:2011/1
+GCAGAGCTGAATGGGCAAGCCCAGGACCCTTTTCAGACATTCTGCTGGCCTTTGGAAAGTGTACTCCTGTTGTATTTGATTACTTTTAGAGGACAGTACAT
++
+CCCFFDDFHHHGHJJJJIJFGIGHJGIJIIIIIHIIGIIJIIIIJJJIIIIJIIIGIJGIJJJJIIJJJEEEE?ECFFFFFFCCEDEEEDDDDDDDDEDCD
+@SRR9130495.102 D00236:723:HG32CBCX2:1:1108:3264:2036/1
+GGGTGCTGGAGATAGCCCACGTACACTCCTTCTTGCTGGGGTACTTGTCAGGCCAGTTGGGGCTGGTGATGGTGCCACTGGTGGATGTCACCTTGTGTTCA
++
+=@<=B+AD>BFDFIIDEDGEIGFIIIIIICDFGFFGIII;D?F>?*/9BF>DAF;CFFGI>/:=?>7@BAA:;@5=A5>@=,98?:>@(;:4>ABAB?ABD
+@SRR9130495.103 D00236:723:HG32CBCX2:1:1108:3400:2065/1
+TCTGTCTGTCACCAGGTTGGAGTGCAGTGGTAGGATCATGGCTCACTGCAGCCTCGTCCTCTTGGGTTCAAGCAATCCTCCTGCCTCAGCCTCCCAGGTAG
++
+@@BDFFFFHHHGHIJJFHEG@GHHIIAFD@HGGGEHIJJJGIJJGGGIHFDAHHHHJFCGGGHGJI;CHFCEDDFFFCEDEEDDDDDDDD<<ABBCCDD>C
+@SRR9130495.104 D00236:723:HG32CBCX2:1:1108:3468:2219/1
+TGCACTTCGTTCTCTTAATGAAACCCTTTGACTTAACCATGACTCCGCTCTGCTCTTGAGTTTGCAAGTGTGTGCGAGTGCCCGAGAGACAGTTTTTTTTT
++
+CCCFFEFFHHHHHJIJIIJJIIJJJIIJJIHIHJJJJJFHFHIIJIJJJJIJIJJJJJGGIIJJJGDIJJJIHHHGFFDDEEEDDDDDDDCCDCEDDDDDD
+@SRR9130495.105 D00236:723:HG32CBCX2:1:1108:3722:2006/1
+TCCATAGTTTCGCAGAAGACTTGGAAGGATGTTGATGTATATGCAGGTCCATTATCAGTTTTTAAATTAGATGGTTTTCCCCAAGCTGCCCATGCGTCTAA
++
+CCCFFFDDHHHHHJJIJJIIHGHIGIIDFHHIIIHHIJJIJJIJIJJJJJJIIJJIJG=DHHJJIJIIIJJJJJIGHGHHFFBFDDEEEDDDDDDBBDDDD
+@SRR9130495.106 D00236:723:HG32CBCX2:1:1108:3517:2148/1
+CTCTGTTCTGTTCCATTGATCTATATCTCTGTTTTGGTACCAGTACCATGCTGTTTTGGTTACTGTAGCCTTGTAGTATAGTTTGAAGTCAGGTAACGTGA
++
+CCCFFEBFHHHHFGGGIEEHIIJIJJIJJIIJIJJHIIJIIJJIIFHGIIIIJJJJJJFIJIJJJJGIIJIJCHIJIJHGJIJHHHHHHFFFFFFEEDECA
+@SRR9130495.107 D00236:723:HG32CBCX2:1:1108:3927:2234/1
+CTGTGCTCTATGTACACGCCCATCTGTTTGCCTGACTACCACAAGCCGCTACCACCGTGCCGTTCCGTGTGCGAGCGCGCCAAGGCCGGCTGCTCGCCGCT
++
+@C@FFFFFHHHHHJJJJGIIJIJJIJEHIIGHGJJIJJJJJJIIGHHIJIJIGHJIIJIHHGFFDEDE?BBDDBDCDDDBDDDDBDD>BDBDDDDBDDDB<
+@SRR9130495.108 D00236:723:HG32CBCX2:1:1108:4124:2011/1
+GACTCAGAGCCAGGGCCCGGGAACAGAGATGACTCGAAGGCTAGGGCTCCAGCCAGACTTACCGGCACACGTACACCTCTAGGGGTGGCAGGGTGCTGGGT
++
+CCCFFDDEGGGHHIJIIIJIIIIJIHHJJIJIIJIJIGGIIGIIHIGGIGHBHGHFEFFEECEDDDDDDDDBDDDDDCBACCDDDDDDBDDDDDDDDCD?9
+@SRR9130495.109 D00236:723:HG32CBCX2:1:1108:4130:2090/1
+TTCTATTTCTATAAACTGGCCTATTTTGGGTATTTCATATATATGGAAATATATAATTTGATTTTTTTGTTCTCTTAGCTGTATGTTTTCAGGATTCTTTC
++
+@BBFDFFFHHGHHIJJJJJJJIIIJJJJIJJJIJJJJIJJIIIJJJIJJJJIJIIJJJJJJJJJIHJIJJHHHHHHFFFFFFEEEDECEEDDDDDCDDEDD
+@SRR9130495.110 D00236:723:HG32CBCX2:1:1108:4176:2091/1
+AAATTGAAAGTAAATGTATACTGTAGTCCCACGCACGAGTGAATAAAGGGGTGTCTAAAAGGAGTGTGTTCTCTTCCAGGCTGCATCTCTCGGTACTCAGC
++
+;8;ABD?+AA=ADBHIGBHE?A<IHGA<ECFGHABFG?DGEFGHIIG@3DBF<;CAC@AHFFFHEEE@DCCACCACCCCCBBBBCC@CCDCB???>CCCCC
+@SRR9130495.111 D00236:723:HG32CBCX2:1:1108:4108:2121/1
+ATGCGGAAGTAGGCAAAAATGATGTGCTAGACTACAAGAATTCCTTTTACAGAAAGTAACAAATACAGAGCCAAGAAAGTTTTTGTTAATTATCACGGTGT
++
+@@@ADADA@AD>FIIBBBFGIBGHJDCIGEGGGHHHIJIIJJJJGHIIEHHEGHJIHGGGIFAGGGGIIG>=CHHFD?@;CCEDDDDCDD>>ACDCB@8<5
+@SRR9130495.112 D00236:723:HG32CBCX2:1:1108:4384:2110/1
+ACACAGGCAGCAATGATGTCTTTACTTCTTTATTTTTTTCGACTTCATCTACAGAGCTTAGCACAGCCATTGGAACAAAATTGGAGCTCAGTGCACAGTTA
++
+@@@FDEFDDFF3CCF?FHCH@DEEGEFHIIFGBGGGDGIHAFBGDDHHIB<CCH>AGGDGHE@CHAHBFFFF<CCEDDDDAC@CADCDAC?AACCCCA4:A
+@SRR9130495.113 D00236:723:HG32CBCX2:1:1108:4449:2134/1
+CTAGCTGGGAGTGGTTAATCCCAGATCTCTGGACACAGGGGTAGATGGAACAACTCAGTGAGTTCCAGACCAATCTGGACTACATAGCAAGTTCTAGGCCA
++
+B@CFDDDDHHHHHJJIIJJJJIJIFGIJJJIJJIIJIIJJJJJIJIIIIGIJGHIIFFHIJIIJIIHHEFHFFFFFEEEEEEDDDFDCDDDDCDEEDCDDD
+@SRR9130495.114 D00236:723:HG32CBCX2:1:1108:4398:2225/1
+GCTGAATAACCAACTGACTATGTTTCAGAAAATCAACCACTTCCCTGGCATGACGGAAATCTGCCGCAAAGATCTGCTGGCTCGGAACCTCAACCGCATGC
++
+CCCFFDFEHHHGGJIIGGIIJJHIJJJGGGHIJJJIIIIJJJIJJJJIJGIJJIIGDIIIJJJJJJHHFFFEEDEDEDDDDDDDDDDDDCDDCDDDD>BDD
+@SRR9130495.115 D00236:723:HG32CBCX2:1:1108:4445:2247/1
+TCTGTATTCTGTGTCATCTGCCATTCCTTGACTCCCTGCGCCCTTCAGCCCACAGGAAACGTGTGGATGACACACGAGGAGATGGAGTCTCTGACGGCAGC
++
+CCCFFDDDHHHHGJJJJIJJJJBHHJJIIGIIJJJIIGIFIJJIIIIGIJJIIIJIJCHIIJJJIHHFHEFFFFDDDDDBDDCDDCDCDDDDCCCDBBDDB
+@SRR9130495.116 D00236:723:HG32CBCX2:1:1108:4698:2005/1
+GAGGGAAGGAGGGAGGGAAAGAAGAAGGGAGAGAGGGAGGAAGGCAGGACTGTCGATGCAAGTACCTCGCTTCCTTGTTCTTAACTCATTTGATTCTTGCT
++
+C@BFFFFFGHHGHIIIJJIBGGDHC@FEGDHIIIHGEHHEGCGIHHHFFFFDEEDDDEDDDDCDCCCDDDDDDDDDDDDDEDCCCDDDCDDDED:CCDDDD
+@SRR9130495.117 D00236:723:HG32CBCX2:1:1108:4588:2182/1
+CTGGGGTGCAGTGGTGCAATCATAGCTCACTGCAGCCTCAATTTCCTAGGCTTAAGCATTTCTTCCACCTCAACTTCCCAAGTAGCCAGGATTACAAGCAC
++
+CCCFFADDFFHHGGHHGIIJIJJJJJJHIIJIJJIFIJJEIIJIJIGIJIJJJJJJIJJJIIHIIJHIIFFHGHHFFFFFEDEECCCCBDBDDDDDDCDBC
+@SRR9130495.118 D00236:723:HG32CBCX2:1:1108:4964:2029/1
+CCCCGTCTCTACTGAAACACACACACACACACACACACACACACACACACAATTAGCCAGGCGTGGCAGCGTCTGCCTGTAGTCCCAGCTACTCAGGAGGC
++
+;8=:DDDDFFFAFIIFFBEIIEFIFIFIEFFFIIBEGEF?BF<4;A@EE/?;AB>7;7;>@?>B?''5<@;@?;0((4:@>34@@>:4<@>BAB@(948&+
+@SRR9130495.119 D00236:723:HG32CBCX2:1:1108:4831:2078/1
+GCGAAGAAAACTGAAAAAGGTGGAAAATTTAGAAATGTCCACTGTAGGACGTGGAATATGGCAAGAAAACTGAAAATCATGGAAAATGAGAAACATCCACT
++
+CCCFFFFFGFHHFFHGIHDICFHIGGIDHIIJJJJIIIIIGIGHGIJJJJJJJJJJJIJJJIJJIHHHHHFFFFFEEEEEEEDDDDDDDDDDDDDDDDCDD
+@SRR9130495.120 D00236:723:HG32CBCX2:1:1108:4877:2117/1
+GCATAATGTTGCCACTGCACTCCAGCTGGGACGACAAAGACTGTCTCTAAAAAAGTAATAAATAAATAAAAGTTTGAAATGCATTGTCCTAGGTTTTAGTC
++
+CCCFFDEFHHHHHIIJJJJJIJIIIGIJJJJJJIIJIJJJIJJJJJJJJJJJJJIIHHGHHHHHFDFFFFFEEEEEEDDDDDCEEDEEDDDDDCDDDDDDD
+@SRR9130495.121 D00236:723:HG32CBCX2:1:1108:4918:2158/1
+AAACATGTCAATGGCCAAAAAAAACAGACAATCAAAAAATGGACAAATATATGAACAGACATTTCTCACAAGAGGACATACAAATGGCCAGCAAATATATA
++
+CCCFFFFDHHGHHIIJIJJJIIIJJJJJJJIJJIJJJIIJJJJIJJIJJIHGFHHHHFFFFFEFEEEEEDDDDDDDDCDDDDDDDCCBCDDDDDDDDEEEE
+@SRR9130495.122 D00236:723:HG32CBCX2:1:1108:4939:2211/1
+CCTGGTCTCAGCATTCCTCACACGTCATAGCGAGGCCCATGGCTGTAGAAATCCCACCATTCTCTTCTCCCCAGGCCTGGCATCCGTAGAAGCCTACAGCT
++
+@CCFFFFFHHHHDHIDIHIJIJJJJJIGGEGIJIIGIIIJJJGGIJJJJIGGHGIIIJJGHHHHHFFFFEFDEDDDDDDBDDDDDDDDD?CDDDDDDDDAC
+@SRR9130495.123 D00236:723:HG32CBCX2:1:1108:5169:2188/1
+TCTGACCCCATGTCCTCAGGCCAGAACCCGGGAGCCTGTCAGAAAAGGTCTCTCACCTAGAGTCCATGCTCTGGAAGCTCCAGGAGGACCTGCAGAGGGTG
++
+??@DD?DFHDFHFIIIIGFHEGGDFFHIBHGIAFIGGIIIFI@CHE@FGH@CDGGIFHEEFCCED@DEEEECCCCCCCCCCCCCCBB8ABC?ACAAABBBB
+@SRR9130495.124 D00236:723:HG32CBCX2:1:1108:5192:2231/1
+ACTCTCCTGGCCCACGAGAGAGTCCACACAGGAGAGAAACCTTACCAGTGTCATGAGTGCGGCAAGAACTTTAGTCAGAAATCCTACCTTCAAAGCCATCA
++
+CCCFFFFFHFHHGJJGEFGHGIIEIIFJJJIHGIJIIJIIIJIIGIEHHIGIHIJIIJIIBDFDDDDDDDDDCDDDCCDDDDDDDCDDCDDDDDCDDDDDA
+@SRR9130495.125 D00236:723:HG32CBCX2:1:1108:5408:2041/1
+TGTGTGCATCCTCATGTGTCCTTGATAAGTGGTGTGATAAATGAAGGCTTTGCCACATTCCTTACACATGTAGGGCTTCTCTCCAGTGTGAGTCCTCTCAT
++
+@@@DDDEBFHHHHIIIHIFHIDHIIIJHHJIHEGFIIHIJJIIJJEIJGHHIEIEGIIJIJJJGIGHGJJIIGIGIHJEHHHHHFFEFFFCC@CEEDDDDE
+@SRR9130495.126 D00236:723:HG32CBCX2:1:1108:5351:2057/1
+CTCTATATATTTTAACAAATGCATAATGTCATGTGTTTACCATTACAGTAGGATAAAGAACAGTCTCATTGCCTTAAAAAGTTCCCTAACATTTTAATTGT
++
+CCCFFDEDFHHHHJIJIIJJJIJJJHJJJJIJIIIHHIJIJIJJJJIIHIJJIIJJJJJIJJJJJJIJIJIJIIJJJJJJJGGIGHHFHFFFFFFFEEEEE
+@SRR9130495.127 D00236:723:HG32CBCX2:1:1108:5475:2108/1
+AGCCCAGAAGGCTGGACACACCTCCCCCTCACCCCATCCCGCTCCCCAATCAACCCAGTCCTCAAGAAGCACACTGTGGCTGCTTGCTCTCTTGCCCCCCT
++
+CCCFFDFFHGHGHJJIJJJIGIIIHIGIIJIIJJJIJJJHGIJIJIIIJHHGHHFFEDEEEECCDDDDDDDDDDDDDDDDDDDDDDDDDDCCDCDDDDDDB
+@SRR9130495.128 D00236:723:HG32CBCX2:1:1108:5542:2138/1
+TGGCTAGCTACTGCTGCTGCTGCATCAAAGCCCAAATATTCACTGGCATCAGCTGTTTTGTTCTTTAGCATATTAGTAAAGTGCTCATTTAGAGACATCTT
++
+@CCFFFFFHHHHGJIJJIJJJIJJJJJJJJJJJJJJIGGIJJJJJHJJJJJJJJJHIEIIJJJIIJJJIJIIJJJJHHHHHHHF@DFFFFEDEEEEDDCDD
+@SRR9130495.129 D00236:723:HG32CBCX2:1:1108:5707:2147/1
+CCAGCATCACTCATGGAACCGGAGGCACTAAGGCCCCTCGGGAGACGCTGAGCAGGTGGGTAGAGGCATACTTCTGGGAGATGGCATCAAGAGCCAGTCAA
++
+CC@FFDDFFDHG>FFFHGGIJIEIIIHIGIGHBHCEHGGGFH@FHGIHHFBFDEEDDEDDDDBDC?BBDCDDDDDC:?A?BDDDCCDC>ACDDDBDDACCC
+@SRR9130495.130 D00236:723:HG32CBCX2:1:1108:5614:2168/1
+AAACCATGTCTCTACTAAAACTACAAAAATTAGCTGGGCAACATGGTGGGTGCCTGTATCCCAGCTACCTGGGAGGGTGAGGCACGAGAATCACTTGAACC
++
+CCCFFFFFHHHHHIJJJJIJGJIJJJIJJJJIJJJJJIJJJJIJJHIIHJIJJJJJJJJJJJJJJJJGHFHHF@DDDDDDDDDDDDDDDBDDDDDDDDDDD
+@SRR9130495.131 D00236:723:HG32CBCX2:1:1108:5985:2027/1
+GCGGCAGCGGCCGCGATGGAAGAACTTACGGCGTTCGTCTCCAAGTCTTTTGACCAGAAAGTGAAGGAGAAGAAGGAGGCCATCACGTACCGGGAGGTGCT
++
+CCCFFFDDHHDGHFIJFHFFHHBFGHGEIJJJFFDDDDDDDDDDD@CCDCDDDDDAAACACDC@CCDBB<BDDDCDDDDBDDDDDDDDDBDDDD<>BDBD@
+@SRR9130495.132 D00236:723:HG32CBCX2:1:1108:5816:2071/1
+TTTACATATAAGAACCTGATGACCTTTTGTTTTTGTCCAGGAGAGTCCTTCTTGTCTACGAAATGCAGCTATCACAGCAGCTGGACTTGTTTCCTGAATGC
++
+C@CFFDDAFFFHHHHHHGFIHJIJFHHHCAAEHIGHJGCCGHIHEHJJJEHGIIIFIGBBAEHGIJIGIIHHEHHHFFFFEECCABCDCCCCACDDACDA:
+@SRR9130495.133 D00236:723:HG32CBCX2:1:1108:5835:2081/1
+CCAGGGCTCCAAGGGGCTGGTTACGAAGTGTCTCCTGCTGCATGAGGTCCCCACGGGAGAGATTGTGGTCCGCCTTGACCTGCAGTTGTTTGATGAGCCGT
++
+@CCDDDFFHHHGHGJGJFHIEHIGCGHIGJGIIIJJJJJJJJJIIIEIJFGIJJIJG<?BC7>CCDDBDDCDDDBDDDDCDDDDDDDD>BACDDDEDDCBD
+@SRR9130495.134 D00236:723:HG32CBCX2:1:1108:5841:2101/1
+GGGCATGGTGGCATGCGCCTGTAGTCCCAGCTATTCGGGAAGCTGAGGCAGGAAAATCTCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCAAGCTTGCA
++
+@CCF?BDDHFHGHIIIIIIIIIGHGHHIIIFIIIIIGGFGGIIIIEFGGEGHCD>CGGFHHHGGHFFFCDDADDDDDDDBDBCDCCCCA@CCCCBDDDDDD
+@SRR9130495.135 D00236:723:HG32CBCX2:1:1108:6165:2044/1
+TTTATACCATTTTTTTTTTTAGCATATATCCTTGTACTTTATAGGAATTATTTGCTTTATTCTCTTGTGACTTGTAAATTGATGTACTTAATTAAATCTTT
++
+@@CBAB;DHFFHHIGIIGGHGFF@?BGB@8=FHEGHIGD=@CGHIA;@EHFHGHBFFFCBD;>(>@A@C>>;>CA;;35>@3;>5>,;3>:;(:@:>:@@C
+@SRR9130495.136 D00236:723:HG32CBCX2:1:1108:6059:2069/1
+CTATGACCGCTATGTTGCCATCTGTAGCCCACTGCTTTATAACACTGTAATGTCCCACAAGGTCTGTTCCATAATGATGGCTGTGGTATACTCACTGGGCT
++
+CCBFFDBEHHHHFEGIIGHGIIIJIIHIJIFIJJJJJJJJJJIIJJIJJJJIIHHIJIIIFIHIJFIGIIIHGGHHHHFFFFDEEEEEDEFEDDDCDDDBC
+@SRR9130495.137 D00236:723:HG32CBCX2:1:1108:6161:2181/1
+ATGAAGCAACAACCTTATAGGCATTTTAACTCATAGGTTTTAAAACTTAAGGTTATTTTCATAGGAGTCCCTTTTAGCAGAAATGCTCACCACAGGACCAG
++
+@@C<DDDEHFDDHGGBFHIHHIGIEIIHGHEFGHHHE9?C?DFG>GGDD@4???BDHCH@GH<=FHGEGGGIGCEG@E7ACH@:77?C@A@CBAA???2<A
+@SRR9130495.138 D00236:723:HG32CBCX2:1:1108:6485:2147/1
+TTGTGCATGCATATCTGGATATGTATCACTAAAGATAATTAAATACAGCAGGTCAAAGATCAGTAACAACCATTAACCAAAAACCAAATAAGCCAAAACCT
++
+@@?DDEFFGFHGAHHGBFHHIIJJHIJJEGIJJGHHJJJJJJJJJJIGIGEIGIEIJJJJJIJHIEFGGGIJIJHIIIEIGHHHFFFCCECEC??CCDDDC
+@SRR9130495.139 D00236:723:HG32CBCX2:1:1108:6335:2229/1
+TTTAAAAAAGATATTTGATATAATTTCAAACTTACCGAATTTGGTAAGCCTTGTTTAGATCGGAAGAGCACACGTCTGAACTCCAGTCACCACTTCGAATC
++
+@@@DFEFFHHFHHIGIIGGGHGGGIIGIIGGHH@FCGHGGJIIIIFHECGHFHIJIJIGGIHGGIGEHGHBDDBCACDDCCDDDDDDDDCCDACCAB<A@?
+@SRR9130495.140 D00236:723:HG32CBCX2:1:1108:6596:2108/1
+CTGGTGACCAAACACACCTGCGTGGCTTTCTGCTAGTGAACCCCCTTTCTGTCAAAACAAGCCCTCGGGCGGCCTCCTGTCCACCCTAGCCTGGCAGGTCA
++
+CCCFFADFHDFHHJJJJJJJJFJJIIJJJJJIIIHIIIIHGGIJJHHJGIJCHGGIGHJHHHGFFFDDCDDDBBDDDDDDDDDDDDDCCDDDDDBDDC?C@
+@SRR9130495.141 D00236:723:HG32CBCX2:1:1108:6612:2130/1
+TTCTACCTGGCAATGCTCCTGTTCATGTTGTTCCTTTGCATGCTGCCCACCATTTTTGCCATTGTCCACTACAAGCCGTCTCTGAACTGTGGTCCCTTCAG
++
+CCCFFFFFHHFFHGJJJJIJJHIJIGIIGIIJIJJIHIJIJJEHIJJJJJIJJJJJIIJIIJHHIJIBGIJJFHIHHHFFFEEEEEEDDDDDDDDDCCDCD
+@SRR9130495.142 D00236:723:HG32CBCX2:1:1108:6763:2034/1
+GATGCTGTCATAGACATTTCGTCCCCACATAACTGCTTTGACAATGCTTGTAAAGTTGTCATCTGTGAGAATAATATCAGACGCTTCTTTAGCCACATCAG
++
+CCCDDDDDHHHGGIJIJJJIJJJJGGIJJGIEIJJIJJJIGGIJIJJJJGIGIIIJIJJJJIIIIIJJIJ@FG@EHIGJHHHHBFDCEDEEDDDDDDDCCC
+@SRR9130495.143 D00236:723:HG32CBCX2:1:1108:6781:2064/1
+AAGGGAGTCGGGGCAGCGGGGCGTGGCAGAGCGGGGAGCTGGACTGTGGTGTAGCTGCGACAGGGCCTTGGCTGACACCTAGATCCCAAGAGTTTAAGCAA
++
+@?@FF=ADH>FFFIGIIGIIIIFDADBDDDDDDDBBBBBBCDD@CDDDD?BDDDDDDCDDBDDDBDDDCCCCCBBCCCDCCCCDDAC>ABDDDCDDDDA@C
+@SRR9130495.144 D00236:723:HG32CBCX2:1:1108:6837:2146/1
+CCTGTTATTTTAGTTGTTAAAGGTGGCATTCTGTTCTTGTGGCTGTCTTCTTTTAGGTTTGTTGAGGGATTACCTTCTTGTTTTTTCTAGGGCATTGTTCC
++
+BCCFDDFDHFDHFGIIIIJIGIIJJIDGHIJIIJJJJJJGFIIIHFHHIJJJIGDGIGHGHIJICHGGEHGCHGFEHFHHFDDDDDDDDDDDC?CDDDDCC
+@SRR9130495.145 D00236:723:HG32CBCX2:1:1108:6804:2189/1
+TGAATCTCTCTTGGCCTCCTCCCCTCTCATGTCCCCTCCTCCCTCCTCTCCACTTACTCCTCCTCCTCCCCTCCCTCCTCCCAGATGGTTCTGTGTCTTTT
++
+CCCFFEFFHHGHHJJJIJJIJJJJIJJJJJIJIFIJIGIIGGJIJJIIIIIGIIJIJIJGIIIJIJJHHHFDFFDCDCCDDDCDBCCDCDDD@ACCCDDDD
+@SRR9130495.146 D00236:723:HG32CBCX2:1:1108:6940:2229/1
+CTTAATGCCACTATCACCACTTCCTTCAAGAGTGAGGGAGAGGAAGAGGAGGAAGAGGAGGAGGAAGAAGAGGAGGAGGAGGAAGAGGAGGGTGAAGGGGA
++
+@@@DBDDEFHHHHGIJIEGGIGECHIFIIJGFHHACCF?D:DFF;?FHH9DFCGGHFG@CA?AB?DD>?A@BDDBB=?B5<B5?AAAB8?BB??8@ADBB5
+@SRR9130495.147 D00236:723:HG32CBCX2:1:1108:6772:2250/1
+GAGGAAGGAAGGAAGGAAGAAGGGAGAGAGGAAGAGAGGGAGGGAGAAAGAAAGGGAAGGAGGAAGGGAGGGAAGGAAGGAGGAAGGAAGAAGAGGGAAGA
++
+?<???DDDF;AF:CEHCAC+ACFFCGFGFHGEII@BGFFG@;FB;@HECE?E>@BBFCAA@A;;5?BB9;=>;BB?1>A?ABD<BBDBDDBACCDDDBA?A
+@SRR9130495.148 D00236:723:HG32CBCX2:1:1108:7203:2046/1
+CCCAGGCTGGTGTGCAATGGCGCGATCCCGGCTCACTGCAAGCTCCGCCCCCCAGGTTCAAGCAATTCTAGATCGGAAGAGCACACGTCTGAACTCCAGTC
++
+@CCFDDFFHFHHHGIIJIHIIGHGGGIJGJEGGHGIJIGIGGGHIIJJIGEDBB?@ACCDEACBCCDDDEDDDDDDDDDDDDDDDDDDDDD<AC@CCC>CC
+@SRR9130495.149 D00236:723:HG32CBCX2:1:1108:7167:2101/1
+TTTCATGTTTTAGGTCTTGTAAGCAAGATTTTTCCTGTTGAAAAACTGGTTGAAGAAGCCATCCAATGTGCAGAAAAAATTGCCAGCAATTCTAAAATCGT
++
+?@?DB?DDHHGDHIHHGBIECFDHHE>C<ACFA@FE?:CEH<DGIIEECBGHGGIIHGIIIEFHF=@@FHHIIIIHHHDFFCECCCDDDDC@@C@C:@@?B
+@SRR9130495.150 D00236:723:HG32CBCX2:1:1108:7286:2036/1
+CCCATTCTTTTCTGGTGAAGGCAAACTGCCCCATCCCCTTATTGGGAAGGGATCTTCTAGCCAAAGTGAGGACCTCTATTTCCTTTGACCCTTCCCCCAAT
++
+CCCFFFFFHGHHHJJJJJJIJIJIIJGHHIIIJJIDIJJIIGIHEHGIDHIIEHIJFHIJIJJIJIJJGHFEHFFFFEEEEEDEEDCDDDBDDDCDCDDDD
+@SRR9130495.151 D00236:723:HG32CBCX2:1:1108:7407:2109/1
+CAAGTATCCCTTGTTCTCCCTTGTGATGATTAGGGTGAGAATGTCCCCAGGAGGCTCAGATGTTTGAACACATAGTCCCCAGTTGGTGGCGCTATTTGGGG
++
+1:?BBADD<?CBCFHABCAAFEC<ACHEEHIII<CEDFHHIHHCC?BD@GGEHGHIIICHHF@GCGDCGHEGHA??>7?BB7;@A(5==;88323>CDC9B
+@SRR9130495.152 D00236:723:HG32CBCX2:1:1108:7449:2110/1
+GGCTTCAGGAGCTTCAGAAGTTAAGAGCTGCAAAAAAGAAGAAAAAGGATCGGCCAAGTAAAGACTGTTCCAAGTTGGACATGCTTGCTAGAAATTTCCAG
++
+CCCFFDFEHGHHGJIIBEEHHIIIHHIGGJIIJIIGIIGGHIIIJIGGGGGGGIIJJHHFHHGFFFFFEEEEEEEDDDDDDDCDDEDDDDDDDDDDDDEDC
+@SRR9130495.153 D00236:723:HG32CBCX2:1:1108:7499:2197/1
+TTCTCATAGTTCAGCTTCCACTTGCGGTAGCTTGTTCCACTTGCGGAACATGTGGTGTTTGGTTTTTTGTACCTGCACTAGTTTGCTGAGAAAGATCGGAA
++
+@@@DDDDEHHFFHABECCAFHHHFDGIHJIIEFGHIIGIGEHEBGG0AEDHGFFFGIDG@EH=ADEBADDE@CCCBCACDDDEEDDCCCBCCC@CC>AB@@
+@SRR9130495.154 D00236:723:HG32CBCX2:1:1108:7309:2205/1
+GGAGGCTGAGGCAGGAGAATCGCTTGGACCCGGGAGGTGTAGGTTGCAGTGAGCCAAGATTGCGCCACTGCACTCCAGCCTGGGTGACAAAGTGAGATATT
++
+BC@FFFDFDHHGFIGIIIJIJJJJJIJJJIIJJJIIIHHIJIJJJIJHHHHGHFFFEBAEECEDDB:@CDDDDCDDDDDDDDDBCBDCDCDDDCD<A@CDD
+@SRR9130495.155 D00236:723:HG32CBCX2:1:1108:7701:2002/1
+CTGCGCCGGCCAAAATCCATCCAGCCCATGTAGTCCCGGTCACTTATTCTATGGCTGGGGTCCAGGCTCTGCAGGTTCTTAAGAACGGACATGCGGCCAGA
++
+;@?ADDDFFHGDFHIJJJJIGGBEI?;FHIIFIGHA@@;F;;CDH)=ECACHHCD9B<AC>BDCC?A<ACCDDDB9:3>CDD34>C@BD<>>:CB<>@BA8
+@SRR9130495.156 D00236:723:HG32CBCX2:1:1108:7518:2119/1
+TTATCAAAGAGGCCCAAGAGAAACCACTTGTCTGACTTCTACCATATGAGTTTAGAATAAGATGATGGCTGCCTATGAGGAAGCAGGCCCTCAACAGATAC
++
+@@@DDBD4CFFAAHII=G9FDHG;?F@;EEBEFCF>BGBGD<F?DCHEFB?FGGB@HAHIG)8=CCGCDGIIHHH@HFED>BECC@BBBBBBBCCABC@CC
+@SRR9130495.157 D00236:723:HG32CBCX2:1:1108:7577:2169/1
+AGTTACTTAATATACCTTAGCCGAAACTTCTGCACTGATTTCCTCCTGTGTTTCAGCCAGCCGCTTTTTGGCAAGTTCGGTTCTCCGATCACACTCTGCAA
++
+@@@DDDFFFFHGHIICGHFH@FGGHGHHJGIHJIJIJGIIIBDHCBGGHEHIJJIGIIIBGIEIGGHHCEBDFEDECD?@DDDDDDDDDDBCCDDDDDDC>
+@SRR9130495.158 D00236:723:HG32CBCX2:1:1108:7659:2196/1
+TTCTGATTTTTGCTGCAGCTTCTGCTTATAATCATATGGCCAGTTGTGCTTGTCAGAGTAATGGTGAAGTCCACAAAACAAATTTCCACATCGGCAGTCAA
++
+CCCFDDDDHDFHFGIFCHIII9FHHIGGHHIJJJJIJJEHGEGIIJJJJJJJJDHGI:DFGIIGHGJGCGHGIJJGIIHGHGFFECB@CEC@B@BDD?CCD
+@SRR9130495.159 D00236:723:HG32CBCX2:1:1108:7733:2213/1
+GGCCAGATGTTTCTGTAAAGATTGAATTAGATCCCCAGGGAGAGGCAGCACAAAGTGCAAATGAATCAAAAACTGAGTAGAATATTGTAGAGTGCCAATTA
++
+@<@DDA+AFFHHHIIFBHC@@F<FHHHEGIIIIIGI;?:D?:DDGHGICGG;F8=BGIED@FEDECGEAEAE8@?BCECC@@@ADDACDC;ACC>>@>CC:
+@SRR9130495.160 D00236:723:HG32CBCX2:1:1108:7590:2217/1
+GGGGCTGGGCCCACCTGGGACAGAGGGCCACATGTAGAGGCAGCGCTCCCCCGTCTTGAGCTGATCTTTGCAGTCGAATAGCATGAGGTTGGCCCAAGCGA
++
+CC@FFDDDGHHDHIJDGII<GIDGEHIIIJGIIGIEGGIJJIEIJGIHIFHHFCDDDDDDDCDCCDECDC(;@C9=8?C?CDDEDACD>ACBDDBBBDDD@
+@SRR9130495.161 D00236:723:HG32CBCX2:1:1108:7735:2228/1
+GCAGCACTGTCTGAGTATGGGAGCAAAGCCTAATCTGGCTTGCCCGGCCTCTCACCTCTGTGGCGCTCTGCATCATGGTGCTTCTTGTCATCTTTTATTGC
++
+?@;DDDDDFCFFHIHHGBHIBH?FHIBDEHB@GEIHIEHGHAFFHGEEH<CEHIGIGIGGIFFC<><<?CCCCCCCFCCCCA@@CCCCCA5>@CC@C@CCA
+@SRR9130495.162 D00236:723:HG32CBCX2:1:1108:7898:2065/1
+GTTGGCTTCCCCCTCCCCTCTCCCGTGAGCTGAAAAGCAACAAGGGCTCCACCAGCCTGCAAAATAAGACTTGGGGGGGGGGGGGCAGGGATTGCTTTTTT
++
+@@@FDDDDHHFHFIJIFHIIJJJDHFGIGIGJAFHIDG>@GGFHGGHJIGCHIIGEEHFGF@CFEECC>;>CCABBD<99B@BD99&)&&+9(3(4>(+:0
+@SRR9130495.163 D00236:723:HG32CBCX2:1:1108:7872:2066/1
+CACGCTGGATGAGTTCCTGTTCAGCGACCTGCAGGCGCTGGAAGTGCTGTTGCTCTACAATAACCACATTGTGGTGGTGGACCGGAATGCCTTTGAGGACA
++
+CCCFFFFFGHGGHJJJJJJJJJJIJJJJJJHJJJJJIJJIJJJIGIJJIJJJJIHHHHHHFFDFFEDDEEEEDDDDBDDDDDDDDDDDDDDDDDDDDDDDD
+@SRR9130495.164 D00236:723:HG32CBCX2:1:1108:7826:2191/1
+ATCTCTGGACCCAAACTGGAGGGTGACATTAAAGTTCCCAGGGTGGATTTGAAGGGCCCAGAAGTGGACATTTCTGCTCCCAAGGTCAATATTGATGGGAA
++
+CCCFFEFFGHHGHIHHIIJIIIJJIJIGIIJIHIGIJJJJIJJBFGGIJJIJJJJJIJIHFHHFFF@EEDEEFEEDDDDDDDDDBACDDF@CDEDEDDBDD
+@SRR9130495.165 D00236:723:HG32CBCX2:1:1108:7791:2195/1
+GGAGAACAGCGTGTAGAGCACTCACAGTCTGCTGCCTTCAGGTGTGGGAGGCACTGCTCACACTGATCTTCTTCCCGGTGTGTGTGGTGTTTGCCTGGATG
++
+CCCFFDEFFGHHHJDIIJJIFJJJJJIJJJGIJJIIJIIIJIJIIGEGHHJJJJJIIFIJJJHHHHFHFFDDFFEDC>9;?BBDDD?CDDDDDDDCC?BDC
+@SRR9130495.166 D00236:723:HG32CBCX2:1:1108:7767:2199/1
+GACTAGCCTGGCCAACATGGCAAAACCCAGTCTCTATTAAAAATACAAAAATTAGCTGGGCATGGTGGTGCACGCCTGTAGTCCCAGCTATTCAAGAGGCT
++
+@@@DDDFFFHHFBHBHBDEHHGGGHIIJIIHIHJIEEEIGHEIHIIGHIIHHGJIEHGI?G@CDHI=CA?BDFF<?ABCDDC@CDA>ACDCCDFCC32??A
+@SRR9130495.167 D00236:723:HG32CBCX2:1:1108:7824:2210/1
+GCACCACCGTGCCTGGCTAATTTTTATATATTTAGTAGAGATTGGGTTTCACTGTGTTGGCCAGGCTGATCTTGAACTCTGGACCTCAGGTGATCCTCCCG
++
+@@@FFDDFDFAHHJJIJIIGHHHHHIIJIIDGG>GHHIGGCGHGIEHGGH>FFHJJJHDGBGHJCGGGHFEHHHHFFFFFECDECEDDDCDDDDCCDDCDD
+@SRR9130495.168 D00236:723:HG32CBCX2:1:1108:8205:2084/1
+CTTAGCCGCTGGTGATGCTAAGGGCATGGTCAAAGTGTGGCAGCTGAGCACAGCCTTCACAGAACAAGGGCCCCGGGAGGTGGAGGACTTGGATCAGCTAG
++
+CCCFFDEDFFHHHJEGIDHHIIIIJJJIJGIJJJGHJIJIJJJIIIJIGGIIGIJJIGHIIJGEFHGBEFDDDBDDD;>B2<@BBDBBCCCCDDDDDDDDD
+@SRR9130495.169 D00236:723:HG32CBCX2:1:1108:8202:2124/1
+GAGACTCTTGCACACATACCGGGGAGCTGGCTCACCCTGGCCCCTCCATCCTGTCAGACTGAAGAGAACAAGTGTCTTAATTTGGGTTTTTCTTATTATTA
++
+CCCFFEFDHFHGHGJIIIJJIJJJIIIGIJJJJFIJJHGIJGHIIJJEEEHFGFFEFECCEEEEDDDDCC<A:>AD>CCDDDDCCD<?BBBDDDDDEEED@
+@SRR9130495.170 D00236:723:HG32CBCX2:1:1108:8398:2058/1
+TTATCTCACTTTATTCTCGTTCTCCTCGGACCTCCGTAGCCATATCACTTGTATAAAATAGGCTGAGATATAGTGACTGTAAGCTGTGATCTCAGTATTCA
++
+@@@FDDFEHHGHHJEGFDEHIGIIJJIJFIIIIGHIDFCGBEGCGHGGGIDHJJGGGJIJE@HHGEECECEHCFFFEFF@CDEDCEDC(;@ACCDCADDDD
+@SRR9130495.171 D00236:723:HG32CBCX2:1:1108:8469:2081/1
+ATGGCAGCCTCCAGCCGCGCACAAGTTTTAGATCTGTACCGGGCGATGATGAGAGAGAGCAAGCATTTCAGCGCCTACAATTACAGGTGACCCGGGGGGAG
++
+@@@DFBDDHFHGHIBFBFGIJIIGHH@GFFHGIJIIIJHIII8GHDDDC@CEDDDBDDDDDCDDDDDDC@CC9@BDDDCD@CDDDDDCCDDCDDDD@@B<B
+@SRR9130495.172 D00236:723:HG32CBCX2:1:1108:8385:2092/1
+CTTGTTGCTCATACTACCTCCCTCCCCAGTAACTTTGACACAATTCTCATGTGCCCTGCAGCTAGCAATGTCTCTCGTCTTCATCCTCCCTCTCAGAAAAT
++
+CCCFFFFFHHGHFIJJJIIDIJJJJJJIIJJJJJJJJJJIIJIGIJJIJJIIHIJJJJJIJJIIGJIIEIIJJJHHHHDFFEEEEEEDDDDDDDDCCDCCC
+@SRR9130495.173 D00236:723:HG32CBCX2:1:1108:8470:2098/1
+CATGCCCCTGCTAACATCAATGCCCAGAAGGAAACCGTCAACCAGCAGCTTCCCATCTGGCATCTGTTTCTGCTCAAAGTCTTGCTCCAGTCCCAGCTGGT
++
+CCCFFDADHHHHHGIIGGHEHIJJJJIJIIIIBFHIIHJGHIIGHFHIJIEHIIGIGIJIJHGHHHHHHHFFFFFEEECDEEECDDDDD@CCACCDDDCD<
+@SRR9130495.174 D00236:723:HG32CBCX2:1:1108:8304:2120/1
+CTAGTACGGCAAGGCCGAACCATCTCATACCAGGGTTGTGCCTCACAGATTTTCTTCTATCACACCCTGGGCTGTACTGAGTGCTTCCTGTATACAGTGAT
++
+CCCFFDDFHHHGFGJJJJIIHIHJJJIJJIHIGCGHIIIJIIIIJIHIJIIHGHHHHHFFFFFFDDCDDDDDDBDCDEDCDDDDEDDDDDDDEDEED@CDE
+@SRR9130495.175 D00236:723:HG32CBCX2:1:1108:8713:2027/1
+CCTCCTGGGCCGCCCCAATGAAGGAGCCAGATGCCATCAAGCTGTTTGTGGGGCAGATCCCGAGGCATCTGGAGGAAAAGGACCTGAAGCCCATCTTCGAG
++
+@@<:BADDBDHHHH<FG??CCGHHIIFG99BB8*988B=<BE3=8=CC6CC<BDB>?@@A=?8=?=BA93>CA??B@A????8<CCA:@:<<@CCCCD8(3
+@SRR9130495.176 D00236:723:HG32CBCX2:1:1108:8742:2116/1
+GGCCGACACTCAGACACTCATTAGAAGGACACTGAGGATACCATCTACCGACCTTTCCGGAAACTAAAGCACCGTTTGATTCTTCTGTATGTAGTTTTGGG
++
+CCCFFFFFHHHGHIJJJJJJJGIJIJFIIIJJIFIJIJIIIJJJIJIGIIJJJJIIHHHGFFDEEEDDCDDCDD??C@CDDEDEDCDDEEEEECADDCBDD
+@SRR9130495.177 D00236:723:HG32CBCX2:1:1108:8654:2133/1
+TTCCGCAGGCACTGCCACGTGGTGGTGTAGAGGATGAAGGCAAAGGACTTGAGCGCAATGGCGATGCTGACGTACAGGTATCTGTAGACCACATTGTCGTA
++
+CCCFFFFFHHHHGIFIHJJ@GHDFGDEDHEIIIJGGGICGIIJJJJJJIJJJJIIHHFFDCCDDDDDDCDDBBDDDEDCDEDDDEEDEDDDDDDCDEEDDD
+@SRR9130495.178 D00236:723:HG32CBCX2:1:1108:8865:2086/1
+CTCCTCCTCCTCCTCCTCCTCCTCCTCCTTCTTCTTTTTTTTTTTTTTTTAACCGAGAAGCGGGCAGAATAATGATCCTGAAAAAGCCCCTGCCTCCGGGA
++
+CCCFFFFFHHHHHJIGGCEFGG@FGEGIGGBHIGGAHGIBGHGIHDDDB0<3((&0-75(+0570&0(+(+((++(4(+:>CD(8&8?()(+224@?@>35
+@SRR9130495.179 D00236:723:HG32CBCX2:1:1108:8868:2131/1
+GTACATTGTATCTTTGTTCTCATTAGTTTCAGAGAAATTATTGATTTCTGCCTTTATTTCATTATTTACCCAAGAGTGATTTGGAAGCAGGTTGTTCAGTT
++
+<;;B?D>DFC:DBF@AEDHHAHHGH:A:AC4?<E;221?EHI*11????D9D<FH@BFBH??:9BFGIGFCGB=D=@=CHGIBDGA)6.7;;7@566.3;;
+@SRR9130495.180 D00236:723:HG32CBCX2:1:1108:8793:2183/1
+ACACAGAGACATGTTTGTACATATAGAAGTGTATGTAAGTATAACTTTGTTATGTTACTCAGCCATGACCTTTGGTTTCTGCGTGGCATTCACTCTAGGTT
++
+CCCFFFFFGHHHHJJIIJFFGIIGJJHIIHHIIJJGGIIGJJIIJJJJJHJFIIJJJJJJJFGIIIIJJJIJJEGHIJJJJIGHHBFEEEEEEEDDDDDDD
+@SRR9130495.181 D00236:723:HG32CBCX2:1:1108:8880:2229/1
+AAAGGTCACCTGAGCCCCATTTGAGTCCCAACAAGCAAGAAAGGAGTCTTTGGACAGTGGTGAATAATCTCAGGCACCCACTTTTCGTTCACATTTTCAAA
++
+CCCFFFFFDFHGGIGIJJIJIHHGJIJIGGIJGJJJJJIEGIGIIJGIIIJJJIJIHIGG@EGIIJGJGHHHHHFEFFDDDBDDCCDDDDCC@CCDCDDDD
+@SRR9130495.182 D00236:723:HG32CBCX2:1:1108:9241:2001/1
+ATATTTTCTCCTTAAGGTACCACAAGTTGATCTGGGGACCTCATAAGATGGATTCCAAAGGAGATGTTTCTGGAGTTCTGATTGCAGGTGGAGAAAATGGA
++
+@@@DFDD?FCFFHCHGBBDBEHDDABEHG?CH@HGIIHIIIEHEC??FDAGGI9?F<F:FHIHIGFF@GDHIEACAEHHH@@;>BFFEDA?ABD@ACCD:>
+@SRR9130495.183 D00236:723:HG32CBCX2:1:1108:9106:2031/1
+CTAGAAATCCTGGATTTTCAGCACAATAACTTAGCCAGGCTCTGGAAACGCGCAAACCCCGGTGGTCCCGTTAATTTCCTGAAGGGGCTGTCTCACCTCCA
++
+C@CFFDFFGGHHFJHIIJGIHCCEHHIGIFIIHIJJFIGJIGIJJIIJHIFGIJIJFFHHFDAD@BCCBDDDDBCC@CDDCCDDA<B<BDDDDDEDDDDDC
+@SRR9130495.184 D00236:723:HG32CBCX2:1:1108:9233:2138/1
+CAGAAGTGGGACAACCTAACAGGACAACTGAGGGACAGATGCGACTGGATTGACCAGGCTATCGTCAAAAGCACACAGTACCAGAGCCTGCTGAGAAGTCT
++
+CCCFFBDDFFFHGJJJJJIJJJIJJIIJIJIJIJIHIIIJIJJIJIIGIJJJGIJJJHHHHHFFFECDDCCDCDDDDDCDCDDDDDDDDDDDDDDDDCDDD
+@SRR9130495.185 D00236:723:HG32CBCX2:1:1108:9017:2163/1
+TTAGATTCAAACTCTAGCTTCACCACTTTCTTTTTTTTTTTTTTTTTTCGAAAGGGGTCCCCCCTCCCTACCCCAGGCTGGGGTCCAGGGGCCAAATTTTG
++
+<@@BDFDDFBBFBBHEABCEFHGHEH3EFGHIIIIHHIII>EFC'8;&+)+((&28&&&+((&)&&++((++8((2(((25(&&&(++(0&&&(+((+4(+
+@SRR9130495.186 D00236:723:HG32CBCX2:1:1108:9230:2213/1
+ACTTAGTGCAGTACCCACTATTCCCGCTCAGGCTCCGAATAGTAGATAGAGGGTTCCGATATCTTTGTGATTGGTTGAGAATAATCAACGATTAATGAACA
++
+CCCFFFFEHGFFHFIICIIFIJHHGBHHGIGJJIJGGHIGFHIGIIJJJIIGJCFIJI@EFDFEDFFCCEEEEDDDBDDDDDDDECCDD@BDDDCDDDCDC
+@SRR9130495.187 D00236:723:HG32CBCX2:1:1108:9264:2024/1
+AACATAAGGTTTCTCATAAAACAAAGAAAAATGTCAATTCAGTTGTGAATTCATATTGATACCTGGAACTCTCCTGCTAGACCACCTCTAAAGGCCCAGGG
++
+CCCFFFFFHHHGHIJJIDJIJJJDHIIJJJJIJJJJJJJIJJGCHIIJJJJJJJJJJIHJJJJJJGIJJIJIJIIIIJJHHHHGFFFFFECEEDDDDBBBB
+@SRR9130495.188 D00236:723:HG32CBCX2:1:1108:9293:2034/1
+GTGGGGAGGTTTGGGAGTGAGCAGCACACCCCAGTTAGACTCCTGTTGGGTTTCATAGGAGCTGGCTGCTGAATGTAAGAGTGCAGGCTACCCCGGGACTT
++
+@@@FDA;1DAFHFIIFBGIGHGADHIGIIIIIIIIHBFEHIIIIIIIIHIACEEEHHBD@CDECECCBBCCACCCCEECCCCCCCCBBBCCCB?9>>>>BC
+@SRR9130495.189 D00236:723:HG32CBCX2:1:1108:9484:2048/1
+ATGTAGAGAGAGGGAAAAAAGGAGAGAGAGAAGGATAAAGAGAAGGATGCACAAGAAGACCAAAATACCTGATCATGTAGGGGAGAGCCTCTGGGAGAAGG
++
+@@@DFDDDCDDFHICFHHDGIIHHCHCFFDGHHDCGIJIH@FFHFHGIIGIJIGIGF@CEBDFF@EECDCCCCCCDDEEEDDDDDDDDDDCDDCD<@BDCB
+@SRR9130495.190 D00236:723:HG32CBCX2:1:1108:9388:2219/1
+AGCTGCTGCGAGATGGTGGCTTGCATCTCCTTGGACGGCCGCTTGTTCTCCTTGAAGATGGCAATCAGCGTGCGGCGCTGCAGGTCTGTGAACACGAGGCG
++
+B?<DDF8BFAFCAAF93A19?;?B94?DCDHG49BDDG8BH;/5;AE>>3=?>;@DF@>CACC>;>@A>',,88>>-09599(+8>C<CDEC@>95>>>00
+@SRR9130495.191 D00236:723:HG32CBCX2:1:1108:9404:2245/1
+TCCGGCTGGTACCTTCATAACTACAGTAATAGAAGACATTGAGTGCCTCCACCGCAGCTGGCCCTCTCTGTTTGTAGCCAAAGATCAGATCTATCCATTCA
++
+CCCFFFFFHHHHHJJIJIIJEIIJJJJJIJJJIJJJIJIIIIIJJJIJJIIJJJJEIJJIHIGHHHFFFFFFDEEEEEDDDDDDDDDDDDDEDCDDDCDCC
+@SRR9130495.192 D00236:723:HG32CBCX2:1:1108:9632:2134/1
+ATAGTGGCTGCTGATGGATGTGCTCTATGCAAGGGAGGTGCTCACTATTTCTGTTCGTCAATTTGTAACCCACGGGAGGAAAGGGAACAAAGAGTGAACAA
++
+CCCFFFFFHHHGAEFFHIICHGIJHGFIIIHIJDGIJJIIIEGIJJIIFHEGHGIICHIIFIJJJJIIJJHHHFFDBDD?BDDDDBDBDDBCDD:@CCCCD
+@SRR9130495.193 D00236:723:HG32CBCX2:1:1108:9647:2175/1
+AATACCAGCCCAAGACTTTGGGAGAAGGGAAGAAAACAAAGTAAAATAACTTACCACTTTGGCCCAGTCCGAGAACAAGTGAAAATACCCAGGCTGCCCCA
++
+CCCFFFDFGHHFHIIJJGIIIJDIIJIJJJJIIHIIIIJJJHCFHHFHIJJJJJJGIHJJJIJJHGHHHFFFDDDDDCD>CCDDDDDDCDDDBDDDDDDDD
+@SRR9130495.194 D00236:723:HG32CBCX2:1:1108:9552:2194/1
+CCATGCCGACACAGGTAGATGGTACGGGGCTGCACGTGGATGTTCATCAGGTAGTATACAATTCGGCTCTGGATGTGGTCCTGCACTCTGTTCACCAAGAA
++
+@@CFFFFFGHGHHJJJIJJJJIJJJIGHFEGGIFIJIJIIIIIJJIIJJIHHHHHHHFFFFFFFDCDDDC@@ACDDCDDDDDDDDDDDDCDDD@CCDDDDD
+@SRR9130495.195 D00236:723:HG32CBCX2:1:1108:9620:2235/1
+CCAATGATGGCCAACTAGGCCATCTTCTACTATGTACGCAGCTAGAGGCACGAGCGCTGGGGGTACCGATTAGTTCATATTGGTGTTCCACCTATAGGGTT
++
+===BD?DBAABD8AC3<E9>?F?D9C<?AA94*@?C<DG706BG**926B;;F>6'5;:>7<<>8:(',&22>(((:>3>+:(+28(43>@B(>:>A((32
+@SRR9130495.196 D00236:723:HG32CBCX2:1:1108:9908:2124/1
+TCTTGTGAAGAAGATGCTGTTGGAAGCCTCTAAGAAGCCCGAACTGAATGCTCTTATAAACAATACCAGAGGAATTATTTTTTACAGTGTCCCTCACCATG
++
+CCCFFFFFHGDFGIIJJIJJIGGJJIIJJIIJHIIIIJJJJI>HHIFIJIJIJJIIHIHIJJJJIHIHHHGFDEFFEEEEEEDDDDDFDEDCCDCDDDDDD
+@SRR9130495.197 D00236:723:HG32CBCX2:1:1108:9923:2206/1
+TGGGGCTGTGAACCGAAGTCTGCTCCTTTGCGTGAGCCACCCCTGCAGCCCCTCCCACAGTTCCTGAGGAGCCTTTAGTCCTCGTCCTTTCTCAGCTGTAT
++
+@BCFFDAFHHHHHIIIIHIIJIIJIIJJJIIIJJIGGIIIJJFGGGGGEIIIGFHHEFFFEECCCC@CB@BDDDCDDCCDCCDDABBBCDDCC@CCDCCCD
+@SRR9130495.198 D00236:723:HG32CBCX2:1:1108:10131:2036/1
+ATGTGCTCAAAGGCTGGGTGGACCTTACCTCCAGTAAACCCCACGTTGTGAAGAAATCCATCAAGTACCTGGAACAAGGAACTCAAGACACCAAAGATGTG
++
+@CCFFFDDFFBHDHIIIBFEGFGHGHGDFHFGIJJIIHDGEGHIJHFHIIIIJJJJJIIIFHHHFHFFFFFFBAEAACBBCADDDDDDDDADBABCCC>AA
+@SRR9130495.199 D00236:723:HG32CBCX2:1:1108:10246:2089/1
+GCCCTGGGATTGTCCCTCTGGGCACAGGGAGTCCTGGGGTTGTCCCTCTGAGTAGTTCTGTTGGGAGAGGAGGCCCTGGGATTGTCCCTCTGGGTACAGGG
++
+CCCFFBDDHHHFHJIIIJJJJIIIIIFIIEHGIGJIJDHJIJIIJJFJIJ@FFCHJJJBEGEHHHDFDCD@DBB;=?A?@BDDDCACDDDDD@?CCCCDCB
+@SRR9130495.200 D00236:723:HG32CBCX2:1:1108:10051:2156/1
+ATGGAGGATGGCACCCTGCAGGCTGGCCCAGGAGGTGCCAGTGGGCCTCGTGCCCTGGAAATAAATAAAATGATTTCTTTTTGGAGGAATGCTCATAAACG
++
+@@CDFFDFGFHFFIJGGII<GIJGIJDIIJJIIDDIIIGIJJIJIJJJJBHGGGHC;E;@DCEFDDCCCCCCDCDECCCDCC=;@??8?CAC>CCDDADDB
diff --git a/docs/notebooks/example.parquet b/docs/notebooks/example.parquet
new file mode 100644
index 00000000..017772b7
Binary files /dev/null and b/docs/notebooks/example.parquet differ
diff --git a/docs/notebooks/report.html b/docs/notebooks/report.html
new file mode 100644
index 00000000..bbdb1bf1
--- /dev/null
+++ b/docs/notebooks/report.html
@@ -0,0 +1,250 @@
+<!DOCTYPE html>
+<html>
+    <head>
+        <meta charset="UTF-8">
+        <title>fastqc-rs report</title>
+        <style>
+            /*!
+ * Bootstrap v4.4.1 (https://getbootstrap.com/)
+ * Copyright 2011-2019 The Bootstrap Authors
+ * Copyright 2011-2019 Twitter, Inc.
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+  * Copyright 2011-2019 The Bootstrap Authors (https://github.com/twbs/bootstrap/graphs/contributors)
+  * Licensed under MIT (https://github.com/twbs/bootstrap/blob/master/LICENSE)
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s=t-a,l=e-u,c=n-a,f=r-u,h=i-a,d=o-u,p=c*c+f*f,g=h*h+d*d;return s*(f*g-p*d)-l*(c*g-p*h)+(s*s+l*l)*(c*d-f*h)<0}function ZD(t,e,n,r,i,o){const a=n-t,u=r-e,s=i-t,l=o-e,c=a*a+u*u,f=s*s+l*l,h=.5/(a*l-u*s),d=(l*c-u*f)*h,p=(a*f-s*c)*h;return d*d+p*p}function QD(t,e,n,r){if(r-n<=20)for(let i=n+1;i<=r;i++){const r=t[i],o=e[r];let a=i-1;for(;a>=n&&e[t[a]]>o;)t[a+1]=t[a--];t[a+1]=r}else{let i=n+1,o=r;KD(t,n+r>>1,i),e[t[n]]>e[t[r]]&&KD(t,n,r),e[t[i]]>e[t[r]]&&KD(t,i,r),e[t[n]]>e[t[i]]&&KD(t,n,i);const a=t[i],u=e[a];for(;;){do{i++}while(e[t[i]]<u);do{o--}while(e[t[o]]>u);if(o<i)break;KD(t,i,o)}t[n+1]=t[o],t[o]=a,r-i+1>=o-n?(QD(t,e,i,r),QD(t,e,n,o-1)):(QD(t,e,n,o-1),QD(t,e,i,r))}}function KD(t,e,n){const r=t[e];t[e]=t[n],t[n]=r}function tC(t){return t[0]}function eC(t){return t[1]}const nC=1e-6;class 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this._.length?this._:null}}class oC{constructor(t,[e,n,r,i]=[0,0,960,500]){if(!((r=+r)>=(e=+e)&&(i=+i)>=(n=+n)))throw new Error("invalid bounds");this.delaunay=t,this._circumcenters=new Float64Array(2*t.points.length),this.vectors=new Float64Array(2*t.points.length),this.xmax=r,this.xmin=e,this.ymax=i,this.ymin=n,this._init()}update(){return this.delaunay.update(),this._init(),this}_init(){const{delaunay:{points:t,hull:e,triangles:n},vectors:r}=this,i=this.circumcenters=this._circumcenters.subarray(0,n.length/3*2);for(let e,r,o=0,a=0,u=n.length;o<u;o+=3,a+=2){const u=2*n[o],s=2*n[o+1],l=2*n[o+2],c=t[u],f=t[u+1],h=t[s],d=t[s+1],p=t[l],g=t[l+1],m=h-c,y=d-f,v=p-c,_=g-f,x=m*m+y*y,b=v*v+_*_,w=2*(m*_-y*v);if(w)if(Math.abs(w)<1e-8)e=(c+p)/2,r=(f+g)/2;else{const t=1/w;e=c+(_*x-y*b)*t,r=f+(m*b-v*x)*t}else e=(c+p)/2-1e8*_,r=(f+g)/2+1e8*v;i[a]=e,i[a+1]=r}let o,a,u,s=e[e.length-1],l=4*s,c=t[2*s],f=t[2*s+1];r.fill(0);for(let n=0;n<e.length;++n)s=e[n],o=l,a=c,u=f,l=4*s,c=t[2*s],f=t[2*s+1],r[o+2]=r[l]=u-f,r[o+3]=r[l+1]=c-a}render(t){const e=null==t?t=new rC:void 0,{delaunay:{halfedges:n,inedges:r,hull:i},circumcenters:o,vectors:a}=this;if(i.length<=1)return null;for(let e=0,r=n.length;e<r;++e){const r=n[e];if(r<e)continue;const i=2*Math.floor(e/3),a=2*Math.floor(r/3),u=o[i],s=o[i+1],l=o[a],c=o[a+1];this._renderSegment(u,s,l,c,t)}let u,s=i[i.length-1];for(let e=0;e<i.length;++e){u=s,s=i[e];const n=2*Math.floor(r[s]/3),l=o[n],c=o[n+1],f=4*u,h=this._project(l,c,a[f+2],a[f+3]);h&&this._renderSegment(l,c,h[0],h[1],t)}return e&&e.value()}renderBounds(t){const e=null==t?t=new rC:void 0;return t.rect(this.xmin,this.ymin,this.xmax-this.xmin,this.ymax-this.ymin),e&&e.value()}renderCell(t,e){const n=null==e?e=new rC:void 0,r=this._clip(t);if(null===r||!r.length)return;e.moveTo(r[0],r[1]);let i=r.length;for(;r[0]===r[i-2]&&r[1]===r[i-1]&&i>1;)i-=2;for(let t=2;t<i;t+=2)r[t]===r[t-2]&&r[t+1]===r[t-1]||e.lineTo(r[t],r[t+1]);return e.closePath(),n&&n.value()}*cellPolygons(){const{delaunay:{points:t}}=this;for(let e=0,n=t.length/2;e<n;++e){const t=this.cellPolygon(e);t&&(t.index=e,yield t)}}cellPolygon(t){const e=new iC;return this.renderCell(t,e),e.value()}_renderSegment(t,e,n,r,i){let o;const a=this._regioncode(t,e),u=this._regioncode(n,r);0===a&&0===u?(i.moveTo(t,e),i.lineTo(n,r)):(o=this._clipSegment(t,e,n,r,a,u))&&(i.moveTo(o[0],o[1]),i.lineTo(o[2],o[3]))}contains(t,e,n){return(e=+e)==e&&(n=+n)==n&&this.delaunay._step(t,e,n)===t}*neighbors(t){const e=this._clip(t);if(e)for(const n of this.delaunay.neighbors(t)){const t=this._clip(n);if(t)t:for(let r=0,i=e.length;r<i;r+=2)for(let o=0,a=t.length;o<a;o+=2)if(e[r]==t[o]&&e[r+1]==t[o+1]&&e[(r+2)%i]==t[(o+a-2)%a]&&e[(r+3)%i]==t[(o+a-1)%a]){yield n;break t}}}_cell(t){const{circumcenters:e,delaunay:{inedges:n,halfedges:r,triangles:i}}=this,o=n[t];if(-1===o)return null;const a=[];let u=o;do{const n=Math.floor(u/3);if(a.push(e[2*n],e[2*n+1]),u=u%3==2?u-2:u+1,i[u]!==t)break;u=r[u]}while(u!==o&&-1!==u);return a}_clip(t){if(0===t&&1===this.delaunay.hull.length)return[this.xmax,this.ymin,this.xmax,this.ymax,this.xmin,this.ymax,this.xmin,this.ymin];const e=this._cell(t);if(null===e)return null;const{vectors:n}=this,r=4*t;return n[r]||n[r+1]?this._clipInfinite(t,e,n[r],n[r+1],n[r+2],n[r+3]):this._clipFinite(t,e)}_clipFinite(t,e){const n=e.length;let r,i,o,a,u,s=null,l=e[n-2],c=e[n-1],f=this._regioncode(l,c);for(let h=0;h<n;h+=2)if(r=l,i=c,l=e[h],c=e[h+1],o=f,f=this._regioncode(l,c),0===o&&0===f)a=u,u=0,s?s.push(l,c):s=[l,c];else{let e,n,h,d,p;if(0===o){if(null===(e=this._clipSegment(r,i,l,c,o,f)))continue;[n,h,d,p]=e}else{if(null===(e=this._clipSegment(l,c,r,i,f,o)))continue;[d,p,n,h]=e,a=u,u=this._edgecode(n,h),a&&u&&this._edge(t,a,u,s,s.length),s?s.push(n,h):s=[n,h]}a=u,u=this._edgecode(d,p),a&&u&&this._edge(t,a,u,s,s.length),s?s.push(d,p):s=[d,p]}if(s)a=u,u=this._edgecode(s[0],s[1]),a&&u&&this._edge(t,a,u,s,s.length);else if(this.contains(t,(this.xmin+this.xmax)/2,(this.ymin+this.ymax)/2))return[this.xmax,this.ymin,this.xmax,this.ymax,this.xmin,this.ymax,this.xmin,this.ymin];return s}_clipSegment(t,e,n,r,i,o){for(;;){if(0===i&&0===o)return[t,e,n,r];if(i&o)return null;let a,u,s=i||o;8&s?(a=t+(n-t)*(this.ymax-e)/(r-e),u=this.ymax):4&s?(a=t+(n-t)*(this.ymin-e)/(r-e),u=this.ymin):2&s?(u=e+(r-e)*(this.xmax-t)/(n-t),a=this.xmax):(u=e+(r-e)*(this.xmin-t)/(n-t),a=this.xmin),i?(t=a,e=u,i=this._regioncode(t,e)):(n=a,r=u,o=this._regioncode(n,r))}}_clipInfinite(t,e,n,r,i,o){let a,u=Array.from(e);if((a=this._project(u[0],u[1],n,r))&&u.unshift(a[0],a[1]),(a=this._project(u[u.length-2],u[u.length-1],i,o))&&u.push(a[0],a[1]),u=this._clipFinite(t,u))for(let e,n=0,r=u.length,i=this._edgecode(u[r-2],u[r-1]);n<r;n+=2)e=i,i=this._edgecode(u[n],u[n+1]),e&&i&&(n=this._edge(t,e,i,u,n),r=u.length);else this.contains(t,(this.xmin+this.xmax)/2,(this.ymin+this.ymax)/2)&&(u=[this.xmin,this.ymin,this.xmax,this.ymin,this.xmax,this.ymax,this.xmin,this.ymax]);return u}_edge(t,e,n,r,i){for(;e!==n;){let n,o;switch(e){case 5:e=4;continue;case 4:e=6,n=this.xmax,o=this.ymin;break;case 6:e=2;continue;case 2:e=10,n=this.xmax,o=this.ymax;break;case 10:e=8;continue;case 8:e=9,n=this.xmin,o=this.ymax;break;case 9:e=1;continue;case 1:e=5,n=this.xmin,o=this.ymin}r[i]===n&&r[i+1]===o||!this.contains(t,n,o)||(r.splice(i,0,n,o),i+=2)}if(r.length>4)for(let t=0;t<r.length;t+=2){const e=(t+2)%r.length,n=(t+4)%r.length;(r[t]===r[e]&&r[e]===r[n]||r[t+1]===r[e+1]&&r[e+1]===r[n+1])&&(r.splice(e,2),t-=2)}return i}_project(t,e,n,r){let i,o,a,u=1/0;if(r<0){if(e<=this.ymin)return null;(i=(this.ymin-e)/r)<u&&(a=this.ymin,o=t+(u=i)*n)}else if(r>0){if(e>=this.ymax)return null;(i=(this.ymax-e)/r)<u&&(a=this.ymax,o=t+(u=i)*n)}if(n>0){if(t>=this.xmax)return null;(i=(this.xmax-t)/n)<u&&(o=this.xmax,a=e+(u=i)*r)}else if(n<0){if(t<=this.xmin)return null;(i=(this.xmin-t)/n)<u&&(o=this.xmin,a=e+(u=i)*r)}return[o,a]}_edgecode(t,e){return(t===this.xmin?1:t===this.xmax?2:0)|(e===this.ymin?4:e===this.ymax?8:0)}_regioncode(t,e){return(t<this.xmin?1:t>this.xmax?2:0)|(e<this.ymin?4:e>this.ymax?8:0)}}const aC=2*Math.PI,uC=Math.pow;function sC(t){return t[0]}function lC(t){return t[1]}function cC(t,e,n){return[t+Math.sin(t+e)*n,e+Math.cos(t-e)*n]}class fC{static from(t,e=sC,n=lC,r){return new fC("length"in t?function(t,e,n,r){const i=t.length,o=new Float64Array(2*i);for(let a=0;a<i;++a){const i=t[a];o[2*a]=e.call(r,i,a,t),o[2*a+1]=n.call(r,i,a,t)}return o}(t,e,n,r):Float64Array.from(function*(t,e,n,r){let i=0;for(const o of t)yield e.call(r,o,i,t),yield n.call(r,o,i,t),++i}(t,e,n,r)))}constructor(t){this._delaunator=new YD(t),this.inedges=new Int32Array(t.length/2),this._hullIndex=new Int32Array(t.length/2),this.points=this._delaunator.coords,this._init()}update(){return this._delaunator.update(),this._init(),this}_init(){const t=this._delaunator,e=this.points;if(t.hull&&t.hull.length>2&&function(t){const{triangles:e,coords:n}=t;for(let t=0;t<e.length;t+=3){const r=2*e[t],i=2*e[t+1],o=2*e[t+2];if((n[o]-n[r])*(n[i+1]-n[r+1])-(n[i]-n[r])*(n[o+1]-n[r+1])>1e-10)return!1}return!0}(t)){this.collinear=Int32Array.from({length:e.length/2},((t,e)=>e)).sort(((t,n)=>e[2*t]-e[2*n]||e[2*t+1]-e[2*n+1]));const t=this.collinear[0],n=this.collinear[this.collinear.length-1],r=[e[2*t],e[2*t+1],e[2*n],e[2*n+1]],i=1e-8*Math.hypot(r[3]-r[1],r[2]-r[0]);for(let t=0,n=e.length/2;t<n;++t){const n=cC(e[2*t],e[2*t+1],i);e[2*t]=n[0],e[2*t+1]=n[1]}this._delaunator=new YD(e)}else delete this.collinear;const n=this.halfedges=this._delaunator.halfedges,r=this.hull=this._delaunator.hull,i=this.triangles=this._delaunator.triangles,o=this.inedges.fill(-1),a=this._hullIndex.fill(-1);for(let t=0,e=n.length;t<e;++t){const e=i[t%3==2?t-2:t+1];-1!==n[t]&&-1!==o[e]||(o[e]=t)}for(let t=0,e=r.length;t<e;++t)a[r[t]]=t;r.length<=2&&r.length>0&&(this.triangles=new Int32Array(3).fill(-1),this.halfedges=new Int32Array(3).fill(-1),this.triangles[0]=r[0],this.triangles[1]=r[1],this.triangles[2]=r[1],o[r[0]]=1,2===r.length&&(o[r[1]]=0))}voronoi(t){return new oC(this,t)}*neighbors(t){const{inedges:e,hull:n,_hullIndex:r,halfedges:i,triangles:o,collinear:a}=this;if(a){const e=a.indexOf(t);return e>0&&(yield a[e-1]),void(e<a.length-1&&(yield a[e+1]))}const u=e[t];if(-1===u)return;let s=u,l=-1;do{if(yield l=o[s],s=s%3==2?s-2:s+1,o[s]!==t)return;if(s=i[s],-1===s){const e=n[(r[t]+1)%n.length];return void(e!==l&&(yield e))}}while(s!==u)}find(t,e,n=0){if((t=+t)!=t||(e=+e)!=e)return-1;const r=n;let i;for(;(i=this._step(n,t,e))>=0&&i!==n&&i!==r;)n=i;return i}_step(t,e,n){const{inedges:r,hull:i,_hullIndex:o,halfedges:a,triangles:u,points:s}=this;if(-1===r[t]||!s.length)return(t+1)%(s.length>>1);let l=t,c=uC(e-s[2*t],2)+uC(n-s[2*t+1],2);const f=r[t];let h=f;do{let r=u[h];const f=uC(e-s[2*r],2)+uC(n-s[2*r+1],2);if(f<c&&(c=f,l=r),h=h%3==2?h-2:h+1,u[h]!==t)break;if(h=a[h],-1===h){if(h=i[(o[t]+1)%i.length],h!==r&&uC(e-s[2*h],2)+uC(n-s[2*h+1],2)<c)return h;break}}while(h!==f);return l}render(t){const e=null==t?t=new rC:void 0,{points:n,halfedges:r,triangles:i}=this;for(let e=0,o=r.length;e<o;++e){const o=r[e];if(o<e)continue;const a=2*i[e],u=2*i[o];t.moveTo(n[a],n[a+1]),t.lineTo(n[u],n[u+1])}return this.renderHull(t),e&&e.value()}renderPoints(t,e=2){const n=null==t?t=new rC:void 0,{points:r}=this;for(let n=0,i=r.length;n<i;n+=2){const i=r[n],o=r[n+1];t.moveTo(i+e,o),t.arc(i,o,e,0,aC)}return n&&n.value()}renderHull(t){const e=null==t?t=new rC:void 0,{hull:n,points:r}=this,i=2*n[0],o=n.length;t.moveTo(r[i],r[i+1]);for(let e=1;e<o;++e){const i=2*n[e];t.lineTo(r[i],r[i+1])}return t.closePath(),e&&e.value()}hullPolygon(){const t=new iC;return this.renderHull(t),t.value()}renderTriangle(t,e){const n=null==e?e=new rC:void 0,{points:r,triangles:i}=this,o=2*i[t*=3],a=2*i[t+1],u=2*i[t+2];return e.moveTo(r[o],r[o+1]),e.lineTo(r[a],r[a+1]),e.lineTo(r[u],r[u+1]),e.closePath(),n&&n.value()}*trianglePolygons(){const{triangles:t}=this;for(let e=0,n=t.length/3;e<n;++e)yield this.trianglePolygon(e)}trianglePolygon(t){const e=new iC;return this.renderTriangle(t,e),e.value()}}function hC(t){pa.call(this,null,t)}hC.Definition={type:"Voronoi",metadata:{modifies:!0},params:[{name:"x",type:"field",required:!0},{name:"y",type:"field",required:!0},{name:"size",type:"number",array:!0,length:2},{name:"extent",type:"array",array:!0,length:2,default:[[-1e5,-1e5],[1e5,1e5]],content:{type:"number",array:!0,length:2}},{name:"as",type:"string",default:"path"}]};const dC=[-1e5,-1e5,1e5,1e5];function pC(t){const e=t[0][0],n=t[0][1];let r=t.length-1;for(;t[r][0]===e&&t[r][1]===n;--r);return"M"+t.slice(0,r+1).join("L")+"Z"}ut(hC,pa,{transform(t,e){const n=t.as||"path",r=e.source;if(!r||!r.length)return e;let i=t.size;i=i?[0,0,i[0],i[1]]:(i=t.extent)?[i[0][0],i[0][1],i[1][0],i[1][1]]:dC;const o=this.value=fC.from(r,t.x,t.y).voronoi(i);for(let t=0,e=r.length;t<e;++t){const e=o.cellPolygon(t);r[t][n]=e?pC(e):null}return e.reflow(t.modified()).modifies(n)}});var gC=Object.freeze({__proto__:null,voronoi:hC}),mC=Math.PI/180,yC=2048;function vC(){var t,e,n,r,i,o,a,u=[256,256],s=kC,l=[],c=Math.random,f={};function h(t,e,n){for(var r,i,o,a=e.x,l=e.y,f=Math.sqrt(u[0]*u[0]+u[1]*u[1]),h=s(u),d=c()<.5?1:-1,p=-d;(r=h(p+=d))&&(i=~~r[0],o=~~r[1],!(Math.min(Math.abs(i),Math.abs(o))>=f));)if(e.x=a+i,e.y=l+o,!(e.x+e.x0<0||e.y+e.y0<0||e.x+e.x1>u[0]||e.y+e.y1>u[1])&&(!n||!xC(e,t,u[0]))&&(!n||wC(e,n))){for(var g,m=e.sprite,y=e.width>>5,v=u[0]>>5,_=e.x-(y<<4),x=127&_,b=32-x,w=e.y1-e.y0,k=(e.y+e.y0)*v+(_>>5),M=0;M<w;M++){g=0;for(var A=0;A<=y;A++)t[k+A]|=g<<b|(A<y?(g=m[M*y+A])>>>x:0);k+=v}return e.sprite=null,!0}return!1}return f.layout=function(){for(var s=function(t){t.width=t.height=1;var e=Math.sqrt(t.getContext("2d").getImageData(0,0,1,1).data.length>>2);t.width=2048/e,t.height=yC/e;var n=t.getContext("2d");return n.fillStyle=n.strokeStyle="red",n.textAlign="center",{context:n,ratio:e}}(Gl()),f=function(t){var e=[],n=-1;for(;++n<t;)e[n]=0;return 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qC="RawCode",PC="Literal",jC="Property",IC="Identifier",$C="ArrayExpression",WC="BinaryExpression",HC="CallExpression",YC="ConditionalExpression",VC="LogicalExpression",GC="MemberExpression",XC="ObjectExpression",JC="UnaryExpression";function ZC(t){this.type=t}var QC,KC,tF,eF,nF;ZC.prototype.visit=function(t){let e,n,r;if(t(this))return 1;for(e=function(t){switch(t.type){case $C:return t.elements;case WC:case VC:return[t.left,t.right];case HC:return[t.callee].concat(t.arguments);case YC:return[t.test,t.consequent,t.alternate];case GC:return[t.object,t.property];case XC:return t.properties;case jC:return[t.key,t.value];case JC:return[t.argument];case IC:case PC:case qC:default:return[]}}(this),n=0,r=e.length;n<r;++n)if(e[n].visit(t))return 1};(QC={})[1]="Boolean",QC[2]="<end>",QC[3]="Identifier",QC[4]="Keyword",QC[5]="Null",QC[6]="Numeric",QC[7]="Punctuator",QC[8]="String",QC[9]="RegularExpression";var rF="Identifier",iF="Unexpected token %0",oF="Invalid regular expression",aF="Invalid regular expression: missing /",uF="Octal literals are not allowed in strict mode.",sF="ILLEGAL",lF="Disabled.",cF=new 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hF(t,e){if(!t)throw new Error("ASSERT: "+e)}function dF(t){return t>=48&&t<=57}function pF(t){return"0123456789abcdefABCDEF".indexOf(t)>=0}function gF(t){return"01234567".indexOf(t)>=0}function mF(t){return 32===t||9===t||11===t||12===t||160===t||t>=5760&&[5760,6158,8192,8193,8194,8195,8196,8197,8198,8199,8200,8201,8202,8239,8287,12288,65279].indexOf(t)>=0}function yF(t){return 10===t||13===t||8232===t||8233===t}function vF(t){return 36===t||95===t||t>=65&&t<=90||t>=97&&t<=122||92===t||t>=128&&cF.test(String.fromCharCode(t))}function _F(t){return 36===t||95===t||t>=65&&t<=90||t>=97&&t<=122||t>=48&&t<=57||92===t||t>=128&&fF.test(String.fromCharCode(t))}const 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t,e;for(t=KC.charCodeAt(tF++),e=String.fromCharCode(t),92===t&&(117!==KC.charCodeAt(tF)&&UF({},iF,sF),++tF,(t=wF("u"))&&"\\"!==t&&vF(t.charCodeAt(0))||UF({},iF,sF),e=t);tF<eF&&_F(t=KC.charCodeAt(tF));)++tF,e+=String.fromCharCode(t),92===t&&(e=e.substr(0,e.length-1),117!==KC.charCodeAt(tF)&&UF({},iF,sF),++tF,(t=wF("u"))&&"\\"!==t&&_F(t.charCodeAt(0))||UF({},iF,sF),e+=t);return e}function AF(){var t,e;return t=tF,{type:1===(e=92===KC.charCodeAt(tF)?MF():function(){var t,e;for(t=tF++;tF<eF;){if(92===(e=KC.charCodeAt(tF)))return tF=t,MF();if(!_F(e))break;++tF}return KC.slice(t,tF)}()).length?3:xF.hasOwnProperty(e)?4:"null"===e?5:"true"===e||"false"===e?1:3,value:e,start:t,end:tF}}function EF(){var t,e,n,r,i=tF,o=KC.charCodeAt(tF),a=KC[tF];switch(o){case 46:case 40:case 41:case 59:case 44:case 123:case 125:case 91:case 93:case 58:case 63:case 126:return++tF,{type:7,value:String.fromCharCode(o),start:i,end:tF};default:if(61===(t=KC.charCodeAt(tF+1)))switch(o){case 43:case 45:case 47:case 60:case 62:case 94:case 124:case 37:case 38:case 42:return tF+=2,{type:7,value:String.fromCharCode(o)+String.fromCharCode(t),start:i,end:tF};case 33:case 61:return tF+=2,61===KC.charCodeAt(tF)&&++tF,{type:7,value:KC.slice(i,tF),start:i,end:tF}}}return">>>="===(r=KC.substr(tF,4))?{type:7,value:r,start:i,end:tF+=4}:">>>"===(n=r.substr(0,3))||"<<="===n||">>="===n?{type:7,value:n,start:i,end:tF+=3}:a===(e=n.substr(0,2))[1]&&"+-<>&|".indexOf(a)>=0||"=>"===e?{type:7,value:e,start:i,end:tF+=2}:"<>=!+-*%&|^/".indexOf(a)>=0?{type:7,value:a,start:i,end:++tF}:void UF({},iF,sF)}function DF(){var t,e,n;if(hF(dF((n=KC[tF]).charCodeAt(0))||"."===n,"Numeric literal must start with a decimal digit or a decimal point"),e=tF,t="","."!==n){if(t=KC[tF++],n=KC[tF],"0"===t){if("x"===n||"X"===n)return++tF,function(t){let e="";for(;tF<eF&&pF(KC[tF]);)e+=KC[tF++];return 0===e.length&&UF({},iF,sF),vF(KC.charCodeAt(tF))&&UF({},iF,sF),{type:6,value:parseInt("0x"+e,16),start:t,end:tF}}(e);if(gF(n))return function(t){let e="0"+KC[tF++];for(;tF<eF&&gF(KC[tF]);)e+=KC[tF++];return(vF(KC.charCodeAt(tF))||dF(KC.charCodeAt(tF)))&&UF({},iF,sF),{type:6,value:parseInt(e,8),octal:!0,start:t,end:tF}}(e);n&&dF(n.charCodeAt(0))&&UF({},iF,sF)}for(;dF(KC.charCodeAt(tF));)t+=KC[tF++];n=KC[tF]}if("."===n){for(t+=KC[tF++];dF(KC.charCodeAt(tF));)t+=KC[tF++];n=KC[tF]}if("e"===n||"E"===n)if(t+=KC[tF++],"+"!==(n=KC[tF])&&"-"!==n||(t+=KC[tF++]),dF(KC.charCodeAt(tF)))for(;dF(KC.charCodeAt(tF));)t+=KC[tF++];else UF({},iF,sF);return vF(KC.charCodeAt(tF))&&UF({},iF,sF),{type:6,value:parseFloat(t),start:e,end:tF}}function CF(){var t,e,n,r;return nF=null,bF(),t=tF,e=function(){var t,e,n,r;for(hF("/"===(t=KC[tF]),"Regular expression literal must start with a slash"),e=KC[tF++],n=!1,r=!1;tF<eF;)if(e+=t=KC[tF++],"\\"===t)yF((t=KC[tF++]).charCodeAt(0))&&UF({},aF),e+=t;else if(yF(t.charCodeAt(0)))UF({},aF);else if(n)"]"===t&&(n=!1);else{if("/"===t){r=!0;break}"["===t&&(n=!0)}return r||UF({},aF),{value:e.substr(1,e.length-2),literal:e}}(),n=function(){var t,e,n;for(e="",n="";tF<eF&&_F((t=KC[tF]).charCodeAt(0));)++tF,"\\"===t&&tF<eF?UF({},iF,sF):(n+=t,e+=t);return n.search(/[^gimuy]/g)>=0&&UF({},oF,n),{value:n,literal:e}}(),r=function(t,e){let n=t;e.indexOf("u")>=0&&(n=n.replace(/\\u\{([0-9a-fA-F]+)\}/g,((t,e)=>{if(parseInt(e,16)<=1114111)return"x";UF({},oF)})).replace(/[\uD800-\uDBFF][\uDC00-\uDFFF]/g,"x"));try{new RegExp(n)}catch(t){UF({},oF)}try{return new RegExp(t,e)}catch(t){return null}}(e.value,n.value),{literal:e.literal+n.literal,value:r,regex:{pattern:e.value,flags:n.value},start:t,end:tF}}function FF(){if(bF(),tF>=eF)return{type:2,start:tF,end:tF};const t=KC.charCodeAt(tF);return vF(t)?AF():40===t||41===t||59===t?EF():39===t||34===t?function(){var t,e,n,r,i="",o=!1;for(hF("'"===(t=KC[tF])||'"'===t,"String literal must starts with a 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0!==o?o:function(e,t){switch(e){case"top":case"bottom":return"horizontal";case"left":case"right":case"none":case void 0:return;default:return"gradient"===t?"horizontal":void 0}}(n,t)}function $d(e,t,n,i){const o=e.getSizeSignalRef(t).signal;return{signal:"clamp(".concat(o,", ").concat(n,", ").concat(i,")")}}function Kd(e){const t=Em(e)?function(e){const{encoding:t}=e,n={};for(const i of[Je,...ws]){const o=ua(t[i]);o&&e.getScaleComponent(i)&&(i===$e&&qr(o)&&o.type===Vi||(n[i]=ep(e,i)))}return n}(e):function(e){const{legends:t,resolve:n}=e.component;for(const i of e.children){Kd(i);for(const o of J(i.component.legends))n.legend[o]=Rd(e.component.resolve,o),"shared"===n.legend[o]&&(t[o]=tp(t[o],i.component.legends[o]),t[o]||(n.legend[o]="independent",delete t[o]))}for(const i of J(t))for(const t of e.children)t.component.legends[i]&&"shared"===n.legend[i]&&delete t.component.legends[i];return t}(e);return e.component.legends=t,t}function Zd(e,t,n,i){switch(t){case"disable":return void 0!==n;case"values":return!!(null==n?void 0:n.values);case"title":if("title"===t&&e===(null==i?void 0:i.title))return!0}return e===(n||{})[t]}function ep(e,t){var n,i,o;let r=e.legend(t);const{markDef:a,encoding:s,config:c}=e,u=c.legend,l=new Ud({},function(e,t){const n=e.scaleName(t);if("trail"===e.mark){if("color"===t)return{stroke:n};if("size"===t)return{strokeWidth:n}}return"color"===t?e.markDef.filled?{fill:n}:{stroke:n}:{[t]:n}}(e,t));!function(e,t,n){var i;const o=null===(i=e.fieldDef(t))||void 0===i?void 0:i.field;Bl(e,(e=>{var i;const r=null!==(i=e.project.hasField[o])&&void 0!==i?i:e.project.hasChannel[t];if(r&&nl.has(e)){var a;const t=null!==(a=n.get("selections"))&&void 0!==a?a:[];t.push(e.name),n.set("selections",t,!1),r.hasLegend=!0}}))}(e,t,l);const f=void 0!==r?!r:u.disable;if(l.set("disable",f,void 0!==r),f)return l;r=r||{};const d=e.getScaleComponent(t).get("type"),p=ua(s[t]),m=qr(p)?null===(n=Di(p.timeUnit))||void 0===n?void 0:n.unit:void 0,h=r.orient||c.legend.orient||"right",g=Xd({legend:r,channel:t,timeUnit:m,scaleType:d}),v={legend:r,channel:t,model:e,markDef:a,encoding:s,fieldOrDatumDef:p,legendConfig:u,config:c,scaleType:d,orient:h,legendType:g,direction:Qd({legend:r,legendType:g,orient:h,legendConfig:u})};for(const n of Wd){if("gradient"===g&&n.startsWith("symbol")||"symbol"===g&&n.startsWith("gradient"))continue;const i=n in Jd?Jd[n](v):r[n];if(void 0!==i){const o=Zd(i,n,r,e.fieldDef(t));(o||void 0===c.legend[n])&&l.set(n,i,o)}}const y=null!==(i=null===(o=r)||void 0===o?void 0:o.encoding)&&void 0!==i?i:{},b=l.get("selections"),x={},w={fieldOrDatumDef:p,model:e,channel:t,legendCmpt:l,legendType:g};for(const t of["labels","legend","title","symbols","gradient","entries"]){var A;const n=Ld(null!==(A=y[t])&&void 0!==A?A:{},e),i=t in Id?Id[t](n,w):n;void 0===i||Y(i)||(x[t]={...(null==b?void 0:b.length)&&qr(p)?{name:"".concat(K(p.field),"_legend_").concat(t)}:{},...(null==b?void 0:b.length)?{interactive:!!b}:{},update:i})}var D;Y(x)||l.set("encode",x,!!(null===(D=r)||void 0===D?void 0:D.encoding));return l}function tp(e,t){if(!e)return t.clone();const n=e.getWithExplicit("orient"),i=t.getWithExplicit("orient");if(n.explicit&&i.explicit&&n.value!==i.value)return;let o=!1;for(const n of Wd){const i=Ec(e.getWithExplicit(n),t.getWithExplicit(n),n,"legend",((e,t)=>{switch(n){case"symbolType":return np(e,t);case"title":return Ma(e,t);case"type":return o=!0,Fc("symbol")}return Cc(e,t,n,"legend")}));e.setWithExplicit(n,i)}var r,a,s,c;o&&((null===(r=e.implicit)||void 0===r||null===(a=r.encode)||void 0===a?void 0:a.gradient)&&ee(e.implicit,["encode","gradient"]),(null===(s=e.explicit)||void 0===s||null===(c=s.encode)||void 0===c?void 0:c.gradient)&&ee(e.explicit,["encode","gradient"]));return e}function np(e,t){return"circle"===t.value?t:e}function ip(e){const t=e.component.legends,n={};for(const i of J(t)){const o=e.getScaleComponent(i),r=P(o.get("domains"));if(n[r])for(const e of n[r]){tp(e,t[i])||n[r].push(t[i])}else n[r]=[t[i].clone()]}return X(n).flat().map((t=>function(e,t){var n;const{disable:i,labelExpr:o,selections:r,...a}=e.combine();if(i)return;!1===t.aria&&null==a.aria&&(a.aria=!1);if(null===(n=a.encode)||void 0===n?void 0:n.symbols){const e=a.encode.symbols.update;!e.fill||"transparent"===e.fill.value||e.stroke||a.stroke||(e.stroke={value:"transparent"});for(const t of ws)a[t]&&delete e[t]}a.title||delete a.title;if(void 0!==o){var s,c;let e=o;(null===(s=a.encode)||void 0===s||null===(c=s.labels)||void 0===c?void 0:c.update)&&Fi(a.encode.labels.update.text)&&(e=ae(o,"datum.label",a.encode.labels.update.text.signal)),function(e,t,n,i){var o,r,a;e.encode=null!==(o=e.encode)&&void 0!==o?o:{},e.encode[t]=null!==(r=e.encode[t])&&void 0!==r?r:{},e.encode[t].update=null!==(a=e.encode[t].update)&&void 0!==a?a:{},e.encode[t].update[n]=i}(a,"labels","text",{signal:e})}return a}(t,e.config))).filter((e=>void 0!==e))}function op(e){return _m(e)||Bm(e)?function(e){return e.children.reduce(((e,t)=>e.concat(t.assembleProjections())),rp(e))}(e):rp(e)}function rp(e){const t=e.component.projection;if(!t||t.merged)return[];const n=t.combine(),{name:i}=n;if(t.data){const o={signal:"[".concat(t.size.map((e=>e.signal)).join(", "),"]")},r=t.data.reduce(((t,n)=>{const i=Fi(n)?n.signal:"data('".concat(e.lookupDataSource(n),"')");return T(t,i)||t.push(i),t}),[]);if(r.length<=0)throw new Error("Projection's fit didn't find any data sources");return[{name:i,size:o,fit:{signal:r.length>1?"[".concat(r.join(", "),"]"):r[0]},...n}]}return[{name:i,translate:{signal:"[width / 2, height / 2]"},...n}]}const ap=["type","clipAngle","clipExtent","center","rotate","precision","reflectX","reflectY","coefficient","distance","fraction","lobes","parallel","radius","ratio","spacing","tilt"];class sp extends Ac{constructor(e,t,n,i){super({...t},{name:e}),this.specifiedProjection=t,this.size=n,this.data=i,Bn(this,"merged",!1)}get isFit(){return!!this.data}}function cp(e){e.component.projection=Em(e)?function(e){if(e.hasProjection){var t;const n=e.specifiedProjection,i=!(n&&(null!=n.scale||null!=n.translate)),o=i?[e.getSizeSignalRef("width"),e.getSizeSignalRef("height")]:void 0,r=i?function(e){const t=[],{encoding:n}=e;for(const i of[[Ge,He],[Ye,Ve]])(ua(n[i[0]])||ua(n[i[1]]))&&t.push({signal:e.getName("geojson_".concat(t.length))});e.channelHasField($e)&&e.typedFieldDef($e).type===Vi&&t.push({signal:e.getName("geojson_".concat(t.length))});0===t.length&&t.push(e.requestDataName(Mc.Main));return t}(e):void 0;return new sp(e.projectionName(!0),{...null!==(t=e.config.projection)&&void 0!==t?t:{},...null!=n?n:{}},o,r)}return}(e):function(e){if(0===e.children.length)return;let t;for(const t of e.children)cp(t);const n=q(e.children,(e=>{const n=e.component.projection;if(n){if(t){const e=function(e,t){const n=q(ap,(n=>!v(e.explicit,n)&&!v(t.explicit,n)||!(!v(e.explicit,n)||!v(t.explicit,n)||P(e.get(n))!==P(t.get(n)))));if(P(e.size)===P(t.size)){if(n)return e;if(P(e.explicit)===P({}))return t;if(P(t.explicit)===P({}))return e}return null}(t,n);return e&&(t=e),!!e}return t=n,!0}return!0}));if(t&&n){const n=e.projectionName(!0),i=new sp(n,t.specifiedProjection,t.size,z(t.data));for(const t of e.children){const e=t.component.projection;e&&(e.isFit&&i.data.push(...t.component.projection.data),t.renameProjection(e.get("name"),n),e.merged=!0)}return i}return}(e)}function up(e,t,n,i){if(ya(t,n)){var o,r;const a=Em(e)&&null!==(o=null!==(r=e.axis(n))&&void 0!==r?r:e.legend(n))&&void 0!==o?o:{},s=Kr(t,{expr:"datum"}),c=Kr(t,{expr:"datum",binSuffix:"end"});return{formulaAs:Kr(t,{binSuffix:"range",forAs:!0}),formula:Ar(s,c,a.format,a.formatType,i)}}return{}}function lp(e,t){return"".concat(Dn(e),"_").concat(t)}function fp(e,t,n){var i;const o=lp(null!==(i=pa(n,void 0))&&void 0!==i?i:{},t);return e.getName("".concat(o,"_bins"))}function dp(e,t,n){let i,o;i=function(e){return"as"in e}(e)?x(e.as)?[e.as,"".concat(e.as,"_end")]:[e.as[0],e.as[1]]:[Kr(e,{forAs:!0}),Kr(e,{binSuffix:"end",forAs:!0})];const r={...pa(t,void 0)},a=lp(r,e.field),{signal:s,extentSignal:c}=function(e,t){return{signal:e.getName("".concat(t,"_bins")),extentSignal:e.getName("".concat(t,"_extent"))}}(n,a);if(En(r.extent)){const e=r.extent,t=e.selection;o=nd(n.getSelectionComponent(K(t),t),e),delete r.extent}return{key:a,binComponent:{bin:r,field:e.field,as:[i],...s?{signal:s}:{},...c?{extentSignal:c}:{},...o?{span:o}:{}}}}class pp extends Hu{clone(){return new pp(null,z(this.bins))}constructor(e,t){super(e),this.bins=t}static makeFromEncoding(e,t){const n=t.reduceFieldDef(((e,n,i)=>{if(Gr(n)&&Fn(n.bin)){const{key:o,binComponent:r}=dp(n,n.bin,t);e[o]={...r,...e[o],...up(t,n,i,t.config)}}return e}),{});return Y(n)?null:new pp(e,n)}static makeFromTransform(e,t,n){const{key:i,binComponent:o}=dp(t,t.bin,n);return new pp(e,{[i]:o})}merge(e,t){for(const n of J(e.bins))n in this.bins?(t(e.bins[n].signal,this.bins[n].signal),this.bins[n].as=U([...this.bins[n].as,...e.bins[n].as],j)):this.bins[n]=e.bins[n];for(const t of e.children)e.removeChild(t),t.parent=this;e.remove()}producedFields(){return new Set(X(this.bins).map((e=>e.as)).flat(2))}dependentFields(){return new Set(X(this.bins).map((e=>e.field)))}hash(){return"Bin ".concat(j(this.bins))}assemble(){return X(this.bins).flatMap((e=>{const t=[],[n,...i]=e.as,{extent:o,...r}=e.bin,a={type:"bin",field:re(e.field),as:n,signal:e.signal,...En(o)?{extent:null}:{extent:o},...e.span?{span:{signal:"span(".concat(e.span,")")}}:{},...r};!o&&e.extentSignal&&(t.push({type:"extent",field:re(e.field),signal:e.extentSignal}),a.extent={signal:e.extentSignal}),t.push(a);for(const e of i)for(let i=0;i<2;i++)t.push({type:"formula",expr:Kr({field:n[i]},{expr:"datum"}),as:e[i]});return e.formula&&t.push({type:"formula",expr:e.formula,as:e.formulaAs}),t}))}}function mp(e,t,n,i){const o=Em(i)?i.encoding[Mt(t)]:void 0;if(Gr(n)&&Em(i)&&jr(t,n,o,i.stack,i.markDef,i.config))e.add(Kr(n,{})),e.add(Kr(n,{suffix:"end"})),n.bin&&ya(n,t)&&e.add(Kr(n,{binSuffix:"range"}));else if(t in ht){const n=function(e){switch(e){case He:return"y";case Ve:return"y2";case Ge:return"x";case Ye:return"x2"}}(t);e.add(i.getName(n))}else e.add(Kr(n));return e}class hp extends Hu{clone(){return new hp(null,new Set(this.dimensions),z(this.measures))}constructor(e,t,n){super(e),this.dimensions=t,this.measures=n}get groupBy(){return this.dimensions}static makeFromEncoding(e,t){let n=!1;t.forEachFieldDef((e=>{e.aggregate&&(n=!0)}));const i={},o=new Set;return n?(t.forEachFieldDef(((e,n)=>{const{aggregate:r,field:a}=e;if(r)if("count"===r){var s;i["*"]=null!==(s=i["*"])&&void 0!==s?s:{},i["*"].count=new Set([Kr(e,{forAs:!0})])}else{if(Ce(r)||Ee(r)){var c;const e=Ce(r)?"argmin":"argmax",t=r[e];i[t]=null!==(c=i[t])&&void 0!==c?c:{},i[t][e]=new Set([Kr({op:e,field:t},{forAs:!0})])}else{var u;i[a]=null!==(u=i[a])&&void 0!==u?u:{},i[a][r]=new Set([Kr(e,{forAs:!0})])}var l;if(vn(n)&&"unaggregated"===t.scaleDomain(n))i[a]=null!==(l=i[a])&&void 0!==l?l:{},i[a].min=new Set([Kr({field:a,aggregate:"min"},{forAs:!0})]),i[a].max=new Set([Kr({field:a,aggregate:"max"},{forAs:!0})])}else mp(o,n,e,t)})),o.size+J(i).length===0?null:new hp(e,o,i)):null}static makeFromTransform(e,t){const n=new Set,i={};for(const e of t.aggregate){const{op:t,field:n,as:a}=e;var o,r;if(t)if("count"===t)i["*"]=null!==(o=i["*"])&&void 0!==o?o:{},i["*"].count=new Set([a||Kr(e,{forAs:!0})]);else i[n]=null!==(r=i[n])&&void 0!==r?r:{},i[n][t]=new Set([a||Kr(e,{forAs:!0})])}for(const e of null!==(a=t.groupby)&&void 0!==a?a:[]){var a;n.add(e)}return n.size+J(i).length===0?null:new hp(e,n,i)}merge(e){return I(this.dimensions,e.dimensions)?(function(e,t){for(const i of J(t)){const o=t[i];for(const t of J(o)){var n;i in e?e[i][t]=new Set([...null!==(n=e[i][t])&&void 0!==n?n:[],...o[t]]):e[i]={[t]:o[t]}}}}(this.measures,e.measures),!0):(function(...e){ai.debug(...e)}("different dimensions, cannot merge"),!1)}addDimensions(e){e.forEach(this.dimensions.add,this.dimensions)}dependentFields(){return new Set([...this.dimensions,...J(this.measures)])}producedFields(){const e=new Set;for(const t of J(this.measures))for(const n of J(this.measures[t])){const i=this.measures[t][n];0===i.size?e.add("".concat(n,"_").concat(t)):i.forEach(e.add,e)}return e}hash(){return"Aggregate ".concat(j({dimensions:this.dimensions,measures:this.measures}))}assemble(){const e=[],t=[],n=[];for(const i of J(this.measures))for(const o of J(this.measures[i]))for(const r of this.measures[i][o])n.push(r),e.push(o),t.push("*"===i?null:re(i));return{type:"aggregate",groupby:[...this.dimensions].map(re),ops:e,fields:t,as:n}}}class gp extends Hu{constructor(e,t,n,i){super(e),this.model=t,this.name=n,this.data=i,Bn(this,"column",void 0),Bn(this,"row",void 0),Bn(this,"facet",void 0),Bn(this,"childModel",void 0);for(const e of xt){const n=t.facet[e];if(n){const{bin:i,sort:o}=n;this[e]={name:t.getName("".concat(e,"_domain")),fields:[Kr(n),...Fn(i)?[Kr(n,{binSuffix:"end"})]:[]],...Er(o)?{sortField:o}:u(o)?{sortIndexField:vd(n,e)}:{}}}}this.childModel=t.child}hash(){let e="Facet";for(const t of xt)this[t]&&(e+=" ".concat(t.charAt(0),":").concat(j(this[t])));return e}get fields(){const e=[];for(const n of xt){var t;(null===(t=this[n])||void 0===t?void 0:t.fields)&&e.push(...this[n].fields)}return e}dependentFields(){const e=new Set(this.fields);for(const t of xt)this[t]&&(this[t].sortField&&e.add(this[t].sortField.field),this[t].sortIndexField&&e.add(this[t].sortIndexField));return e}producedFields(){return new Set}getSource(){return this.name}getChildIndependentFieldsWithStep(){const e={};for(const t of Zt){const n=this.childModel.component.scales[t];if(n&&!n.merged){const i=n.get("type"),o=n.get("range");if(go(i)&&ki(o)){const n=am(sm(this.childModel,t));n?e[t]=n:si(Mn(t))}}}return e}assembleRowColumnHeaderData(e,t,n){const i={row:"y",column:"x"}[e],o=[],r=[],a=[];n&&n[i]&&(t?(o.push("distinct_".concat(n[i])),r.push("max")):(o.push(n[i]),r.push("distinct")),a.push("distinct_".concat(n[i])));const{sortField:s,sortIndexField:c}=this[e];if(s){const{op:e=Dr,field:t}=s;o.push(t),r.push(e),a.push(Kr(s,{forAs:!0}))}else c&&(o.push(c),r.push("max"),a.push(c));return{name:this[e].name,source:null!=t?t:this.data,transform:[{type:"aggregate",groupby:this[e].fields,...o.length?{fields:o,ops:r,as:a}:{}}]}}assembleFacetHeaderData(e){const{columns:t}=this.model.layout,{layoutHeaders:n}=this.model.component,i=[],o={};for(const e of wd){for(const t of Ad){var r;const i=null!==(r=n[e]&&n[e][t])&&void 0!==r?r:[];for(const t of i){var a;if((null===(a=t.axes)||void 0===a?void 0:a.length)>0){o[e]=!0;break}}}if(o[e]){const n='length(data("'.concat(this.facet.name,'"))'),o="row"===e?t?{signal:"ceil(".concat(n," / ").concat(t,")")}:1:t?{signal:"min(".concat(n,", ").concat(t,")")}:{signal:n};i.push({name:"".concat(this.facet.name,"_").concat(e),transform:[{type:"sequence",start:0,stop:o}]})}}const{row:s,column:c}=o;return(s||c)&&i.unshift(this.assembleRowColumnHeaderData("facet",null,e)),i}assemble(){const e=[];let t=null;const n=this.getChildIndependentFieldsWithStep(),{column:i,row:o,facet:r}=this;if(i&&o&&(n.x||n.y)){var a,s;t="cross_".concat(this.column.name,"_").concat(this.row.name);const i=[].concat(null!==(a=n.x)&&void 0!==a?a:[],null!==(s=n.y)&&void 0!==s?s:[]),o=i.map((()=>"distinct"));e.push({name:t,source:this.data,transform:[{type:"aggregate",groupby:this.fields,fields:i,ops:o}]})}for(const i of[Pe,Ne])this[i]&&e.push(this.assembleRowColumnHeaderData(i,t,n));if(r){const t=this.assembleFacetHeaderData(n);t&&e.push(...t)}return e}}function vp(e){return"'"===e[0]&&"'"===e[e.length-1]||'"'===e[0]&&'"'===e[e.length-1]?e.slice(1,-1):e}function yp(e){const t={};return S(e.filter,(e=>{if(Ti(e)){let i=null;if(_i(e))i=Aa(e.equal);else if(Oi(e))i=Aa(e.lte);else if(zi(e))i=Aa(e.lt);else if(Ni(e))i=Aa(e.gt);else if(Pi(e))i=Aa(e.gte);else if(ji(e))i=e.range[0];else if(Mi(e)){var n;i=(null!==(n=e.oneOf)&&void 0!==n?n:e.in)[0]}i&&(ci(i)?t[e.field]="date":b(i)?t[e.field]="number":x(i)&&(t[e.field]="string")),e.timeUnit&&(t[e.field]="date")}})),t}function bp(e){const t={};function n(e){var n;ha(e)?t[e.field]="date":"quantitative"===e.type&&(x(n=e.aggregate)&&T(["min","max"],n))?t[e.field]="number":ce(e.field)>1?e.field in t||(t[e.field]="flatten"):Yr(e)&&Er(e.sort)&&ce(e.sort.field)>1&&(e.sort.field in t||(t[e.sort.field]="flatten"))}if((Em(e)||Sm(e))&&e.forEachFieldDef(((t,i)=>{if(Gr(t))n(t);else{const o=Pt(i),r=e.fieldDef(o);n({...t,type:r.type})}})),Em(e)){const{mark:n,markDef:i,encoding:o}=e;if(Jo(n)&&!e.encoding.order){const e=o["horizontal"===i.orient?"y":"x"];qr(e)&&"quantitative"===e.type&&!(e.field in t)&&(t[e.field]="number")}}return t}class xp extends Hu{clone(){return new xp(null,z(this._parse))}constructor(e,t){super(e),Bn(this,"_parse",void 0),this._parse=t}hash(){return"Parse ".concat(j(this._parse))}static makeExplicit(e,t,n){let i={};const o=t.data;return!Oc(o)&&o&&o.format&&o.format.parse&&(i=o.format.parse),this.makeWithAncestors(e,i,{},n)}static makeWithAncestors(e,t,n,i){for(const e of J(n)){const t=i.getWithExplicit(e);void 0!==t.value&&(t.explicit||t.value===n[e]||"derived"===t.value||"flatten"===n[e]?delete n[e]:si(Un(e,n[e],t.value)))}for(const e of J(t)){const n=i.get(e);void 0!==n&&(n===t[e]?delete t[e]:si(Un(e,t[e],n)))}const o=new Ac(t,n);i.copyAll(o);const r={};for(const e of J(o.combine())){const t=o.get(e);null!==t&&(r[e]=t)}return 0===J(r).length||i.parseNothing?null:new xp(e,r)}get parse(){return this._parse}merge(e){this._parse={...this._parse,...e.parse},e.remove()}assembleFormatParse(){const e={};for(const t of J(this._parse)){const n=this._parse[t];1===ce(t)&&(e[t]=n)}return e}producedFields(){return new Set(J(this._parse))}dependentFields(){return new Set(J(this._parse))}assembleTransforms(e=!1){return J(this._parse).filter((t=>!e||ce(t)>1)).map((e=>{const t=function(e,t){const n=ne(e);if("number"===t)return"toNumber(".concat(n,")");if("boolean"===t)return"toBoolean(".concat(n,")");if("string"===t)return"toString(".concat(n,")");if("date"===t)return"toDate(".concat(n,")");if("flatten"===t)return n;if(0===t.indexOf("date:")){const e=vp(t.slice(5,t.length));return"timeParse(".concat(n,",'").concat(e,"')")}if(0===t.indexOf("utc:")){const e=vp(t.slice(4,t.length));return"utcParse(".concat(n,",'").concat(e,"')")}return si('Unrecognized parse "'.concat(t,'".')),null}(e,this._parse[e]);if(!t)return null;return{type:"formula",expr:t,as:se(e)}})).filter((e=>null!==e))}}class wp extends Hu{clone(){return new wp(null)}constructor(e){super(e)}dependentFields(){return new Set}producedFields(){return new Set([Ds])}hash(){return"Identifier"}assemble(){return{type:"identifier",as:Ds}}}class Ap extends Hu{clone(){return new Ap(null,this.params)}constructor(e,t){super(e),this.params=t}dependentFields(){return new Set}producedFields(){}hash(){return"Graticule ".concat(j(this.params))}assemble(){return{type:"graticule",...!0===this.params?{}:this.params}}}class Dp extends Hu{clone(){return new Dp(null,this.params)}constructor(e,t){super(e),this.params=t}dependentFields(){return new Set}producedFields(){var e;return new Set([null!==(e=this.params.as)&&void 0!==e?e:"data"])}hash(){return"Hash ".concat(j(this.params))}assemble(){return{type:"sequence",...this.params}}}class Fp extends Hu{constructor(e){var t;let n;if(super(null),Bn(this,"_data",void 0),Bn(this,"_name",void 0),Bn(this,"_generator",void 0),Oc(e=null!==(t=e)&&void 0!==t?t:{name:"source"})||(n=e.format?{...N(e.format,["parse"])}:{}),_c(e))this._data={values:e.values};else if(Bc(e)){if(this._data={url:e.url},!n.type){let t=/(?:\.([^.]+))?$/.exec(e.url)[1];T(["json","csv","tsv","dsv","topojson"],t)||(t="json"),n.type=t}}else Pc(e)?this._data={values:[{type:"Sphere"}]}:(zc(e)||Oc(e))&&(this._data={});this._generator=Oc(e),e.name&&(this._name=e.name),n&&!Y(n)&&(this._data.format=n)}dependentFields(){return new Set}producedFields(){}get data(){return this._data}hasName(){return!!this._name}get isGenerator(){return this._generator}get dataName(){return this._name}set dataName(e){this._name=e}set parent(e){throw new Error("Source nodes have to be roots.")}remove(){throw new Error("Source nodes are roots and cannot be removed.")}hash(){throw new Error("Cannot hash sources")}assemble(){return{name:this._name,...this._data,transform:[]}}}function kp(e){return e instanceof Fp||e instanceof Ap||e instanceof Dp}var Cp=new WeakMap;class Ep{constructor(){Cp.set(this,{writable:!0,value:void 0}),_n(this,Cp,!1)}setModified(){_n(this,Cp,!0)}get modifiedFlag(){return function(e,t){var n=t.get(e);if(!n)throw new TypeError("attempted to get private field on non-instance");return n.get?n.get.call(e):n.value}(this,Cp)}}class Sp extends Ep{getNodeDepths(e,t,n){n.set(e,t);for(const i of e.children)this.getNodeDepths(i,t+1,n);return n}optimize(e){const t=[...this.getNodeDepths(e,0,new Map).entries()].sort(((e,t)=>t[1]-e[1]));for(const e of t)this.run(e[0]);return this.modifiedFlag}}class Bp extends Ep{optimize(e){this.run(e);for(const t of e.children)this.optimize(t);return this.modifiedFlag}}class _p extends Bp{mergeNodes(e,t){const n=t.shift();for(const i of t)e.removeChild(i),i.parent=n,i.remove()}run(e){const t=e.children.map((e=>e.hash())),n={};for(let i=0;i<t.length;i++)void 0===n[t[i]]?n[t[i]]=[e.children[i]]:n[t[i]].push(e.children[i]);for(const t of J(n))n[t].length>1&&(this.setModified(),this.mergeNodes(e,n[t]))}}class zp extends Bp{constructor(e){super(),Bn(this,"requiresSelectionId",void 0),this.requiresSelectionId=e&&zl(e)}run(e){e instanceof wp&&(this.requiresSelectionId&&(kp(e.parent)||e.parent instanceof hp||e.parent instanceof xp)||(this.setModified(),e.remove()))}}class Op extends Ep{optimize(e){return this.run(e,new Set),this.modifiedFlag}run(e,t){let n=new Set;e instanceof Vu&&(n=e.producedFields(),H(n,t)&&(this.setModified(),e.removeFormulas(t),0===e.producedFields.length&&e.remove()));for(const i of e.children)this.run(i,new Set([...t,...n]))}}class Np extends Bp{constructor(){super()}run(e){e instanceof Gu&&!e.isRequired()&&(this.setModified(),e.remove())}}class Pp extends Sp{run(e){if(!(kp(e)||e.numChildren()>1))for(const t of e.children)if(t instanceof xp)if(e instanceof xp)this.setModified(),e.merge(t);else{if(V(e.producedFields(),t.dependentFields()))continue;this.setModified(),t.swapWithParent()}}}class jp extends Sp{run(e){const t=[...e.children],n=e.children.filter((e=>e instanceof xp));if(e.numChildren()>1&&n.length>=1){const i={},o=new Set;for(const e of n){const t=e.parse;for(const e of J(t))e in i?i[e]!==t[e]&&o.add(e):i[e]=t[e]}for(const e of o)delete i[e];if(!Y(i)){this.setModified();const n=new xp(e,i);for(const o of t){if(o instanceof xp)for(const e of J(i))delete o.parse[e];e.removeChild(o),o.parent=n,o instanceof xp&&0===J(o.parse).length&&o.remove()}}}}}class Mp extends Sp{run(e){e instanceof Gu||e.numChildren()>0||e instanceof gp||e instanceof Fp||(this.setModified(),e.remove())}}class Tp extends Sp{run(e){const t=e.children.filter((e=>e instanceof Vu)),n=t.pop();for(const e of t)this.setModified(),n.merge(e)}}class Lp extends Sp{run(e){const t=e.children.filter((e=>e instanceof hp)),n={};for(const e of t){const t=j(e.groupBy);t in n||(n[t]=[]),n[t].push(e)}for(const t of J(n)){const i=n[t];if(i.length>1){const t=i.pop();for(const n of i)t.merge(n)&&(e.removeChild(n),n.parent=t,n.remove(),this.setModified())}}}}class qp extends Sp{constructor(e){super(),this.model=e}run(e){const t=!(kp(e)||e instanceof ed||e instanceof xp||e instanceof wp),n=[],i=[];for(const o of e.children)o instanceof pp&&(t&&!V(e.producedFields(),o.dependentFields())?n.push(o):i.push(o));if(n.length>0){const t=n.pop();for(const e of n)t.merge(e,this.model.renameSignal.bind(this.model));this.setModified(),e instanceof pp?e.merge(t,this.model.renameSignal.bind(this.model)):t.swapWithParent()}if(i.length>1){const e=i.pop();for(const t of i)e.merge(t,this.model.renameSignal.bind(this.model));this.setModified()}}}class Rp extends Sp{run(e){const t=[...e.children];if(!L(t,(e=>e instanceof Gu))||e.numChildren()<=1)return;const n=[];let i;for(const o of t)if(o instanceof Gu){let t=o;for(;1===t.numChildren();){const[e]=t.children;if(!(e instanceof Gu))break;t=e}n.push(...t.children),i?(e.removeChild(o),o.parent=i.parent,i.parent.removeChild(i),i.parent=t,this.setModified()):i=t}else n.push(o);if(n.length){this.setModified();for(const e of n)e.parent.removeChild(e),e.parent=i}}}class Wp extends Hu{clone(){return new Wp(null,z(this.transform))}constructor(e,t){super(e),this.transform=t}addDimensions(e){this.transform.groupby=U(this.transform.groupby.concat(e),(e=>e))}dependentFields(){const e=new Set;return this.transform.groupby&&this.transform.groupby.forEach(e.add,e),this.transform.joinaggregate.map((e=>e.field)).filter((e=>void 0!==e)).forEach(e.add,e),e}producedFields(){return new Set(this.transform.joinaggregate.map(this.getDefaultName))}getDefaultName(e){var t;return null!==(t=e.as)&&void 0!==t?t:Kr(e)}hash(){return"JoinAggregateTransform ".concat(j(this.transform))}assemble(){const e=[],t=[],n=[];for(const i of this.transform.joinaggregate)t.push(i.op),n.push(this.getDefaultName(i)),e.push(void 0===i.field?null:i.field);const i=this.transform.groupby;return{type:"joinaggregate",as:n,ops:t,fields:e,...void 0!==i?{groupby:i}:{}}}}class Up extends Hu{clone(){return new Up(null,z(this._stack))}constructor(e,t){super(e),Bn(this,"_stack",void 0),this._stack=t}static makeFromTransform(e,t){const{stack:n,groupby:i,as:o,offset:r="zero"}=t,a=[],s=[];if(void 0!==t.sort)for(const e of t.sort)a.push(e.field),s.push(ue(e.order,"ascending"));const c={field:a,order:s};let l;return l=function(e){return u(e)&&e.every((e=>x(e)))&&e.length>1}(o)?o:x(o)?[o,o+"_end"]:[t.stack+"_start",t.stack+"_end"],new Up(e,{stackField:n,groupby:i,offset:r,sort:c,facetby:[],as:l})}static makeFromEncoding(e,t){const n=t.stack,{encoding:i}=t;if(!n)return null;const{groupbyChannel:o,fieldChannel:r,offset:a,impute:s}=n;let c;if(o){c=ca(i[o])}const l=function(e){return e.stack.stackBy.reduce(((e,t)=>{const n=Kr(t.fieldDef);return n&&e.push(n),e}),[])}(t),f=t.encoding.order;let d;return d=u(f)||qr(f)?Na(f):l.reduce(((e,t)=>(e.field.push(t),e.order.push("y"===r?"descending":"ascending"),e)),{field:[],order:[]}),new Up(e,{dimensionFieldDef:c,stackField:t.vgField(r),facetby:[],stackby:l,sort:d,offset:a,impute:s,as:[t.vgField(r,{suffix:"start",forAs:!0}),t.vgField(r,{suffix:"end",forAs:!0})]})}get stack(){return this._stack}addDimensions(e){this._stack.facetby.push(...e)}dependentFields(){const e=new Set;return e.add(this._stack.stackField),this.getGroupbyFields().forEach(e.add,e),this._stack.facetby.forEach(e.add,e),this._stack.sort.field.forEach(e.add,e),e}producedFields(){return new Set(this._stack.as)}hash(){return"Stack ".concat(j(this._stack))}getGroupbyFields(){const{dimensionFieldDef:e,impute:t,groupby:n}=this._stack;return e?e.bin?t?[Kr(e,{binSuffix:"mid"})]:[Kr(e,{}),Kr(e,{binSuffix:"end"})]:[Kr(e)]:null!=n?n:[]}assemble(){const e=[],{facetby:t,dimensionFieldDef:n,stackField:i,stackby:o,sort:r,offset:a,impute:s,as:c}=this._stack;if(s&&n){const{band:r=.5,bin:a}=n;a&&e.push({type:"formula",expr:"".concat(r,"*")+Kr(n,{expr:"datum"})+"+".concat(1-r,"*")+Kr(n,{expr:"datum",binSuffix:"end"}),as:Kr(n,{binSuffix:"mid",forAs:!0})}),e.push({type:"impute",field:i,groupby:[...o,...t],key:Kr(n,{binSuffix:"mid"}),method:"value",value:0})}return e.push({type:"stack",groupby:[...this.getGroupbyFields(),...t],field:i,sort:r,as:c,offset:a}),e}}class Ip extends Hu{clone(){return new Ip(null,z(this.transform))}constructor(e,t){super(e),this.transform=t}addDimensions(e){this.transform.groupby=U(this.transform.groupby.concat(e),(e=>e))}dependentFields(){var e,t;const n=new Set;return(null!==(e=this.transform.groupby)&&void 0!==e?e:[]).forEach(n.add,n),(null!==(t=this.transform.sort)&&void 0!==t?t:[]).forEach((e=>n.add(e.field))),this.transform.window.map((e=>e.field)).filter((e=>void 0!==e)).forEach(n.add,n),n}producedFields(){return new Set(this.transform.window.map(this.getDefaultName))}getDefaultName(e){var t;return null!==(t=e.as)&&void 0!==t?t:Kr(e)}hash(){return"WindowTransform ".concat(j(this.transform))}assemble(){const e=[],t=[],n=[],i=[];for(const o of this.transform.window)t.push(o.op),n.push(this.getDefaultName(o)),i.push(void 0===o.param?null:o.param),e.push(void 0===o.field?null:o.field);const o=this.transform.frame,r=this.transform.groupby;if(o&&null===o[0]&&null===o[1]&&t.every((e=>Se(e))))return{type:"joinaggregate",as:n,ops:t,fields:e,...void 0!==r?{groupby:r}:{}};const a=[],s=[];if(void 0!==this.transform.sort)for(const e of this.transform.sort){var c;a.push(e.field),s.push(null!==(c=e.order)&&void 0!==c?c:"ascending")}const u={field:a,order:s},l=this.transform.ignorePeers;return{type:"window",params:i,as:n,ops:t,fields:e,sort:u,...void 0!==l?{ignorePeers:l}:{},...void 0!==r?{groupby:r}:{},...void 0!==o?{frame:o}:{}}}}function Hp(e){if(e instanceof gp)if(1!==e.numChildren()||e.children[0]instanceof Gu){const n=e.model.component.data.main;Gp(n);const i=(t=e,function e(n){if(!(n instanceof gp)){const i=n.clone();if(i instanceof Gu){const e=Vp+i.getSource();i.setSource(e),t.model.component.data.outputNodes[e]=i}else(i instanceof hp||i instanceof Up||i instanceof Ip||i instanceof Wp)&&i.addDimensions(t.fields);for(const t of n.children.flatMap(e))t.parent=i;return[i]}return n.children.flatMap(e)}),o=e.children.map(i).flat();for(const e of o)e.parent=n}else{const t=e.children[0];(t instanceof hp||t instanceof Up||t instanceof Ip||t instanceof Wp)&&t.addDimensions(e.fields),t.swapWithParent(),Hp(e)}else e.children.map(Hp);var t}function Gp(e){if(e instanceof Gu&&e.type===Mc.Main&&1===e.numChildren()){const t=e.children[0];t instanceof gp||(t.swapWithParent(),Gp(e))}}const Vp="scale_";function Yp(e){for(const t of e){for(const e of t.children)if(e.parent!==t)return!1;if(!Yp(t.children))return!1}return!0}function Jp(e,t){let n=!1;for(const i of t)n=e.optimize(i)||n;return n}function Xp(e,t,n){let i=e.sources,o=!1;return o=Jp(new Np,i)||o,o=Jp(new zp(t),i)||o,i=i.filter((e=>e.numChildren()>0)),o=Jp(new Mp,i)||o,i=i.filter((e=>e.numChildren()>0)),n||(o=Jp(new Pp,i)||o,o=Jp(new qp(t),i)||o,o=Jp(new Op,i)||o,o=Jp(new jp,i)||o,o=Jp(new Lp,i)||o,o=Jp(new Tp,i)||o,o=Jp(new _p,i)||o,o=Jp(new Rp,i)||o),e.sources=i,o}class Qp{constructor(e){Bn(this,"signal",void 0),Object.defineProperty(this,"signal",{enumerable:!0,get:e})}static fromName(e,t){return new Qp((()=>e(t)))}}function $p(e){Em(e)?function(e){const t=e.component.scales;for(const n of J(t)){const i=Kp(e,n);if(t[n].setWithExplicit("domains",i),nm(e,n),e.component.data.isFaceted){let t=e;for(;!Sm(t)&&t.parent;)t=t.parent;if("shared"===t.component.resolve.scale[n])for(const e of i.value)Ci(e)&&(e.data=Vp+e.data.replace(Vp,""))}}}(e):function(e){for(const t of e.children)$p(t);const t=e.component.scales;for(const n of J(t)){let i,o=null;for(const t of e.children){const e=t.component.scales[n];if(e){i=void 0===i?e.getWithExplicit("domains"):Ec(i,e.getWithExplicit("domains"),"domains","scale",om);const t=e.get("selectionExtent");o&&t&&o.selection!==t.selection&&si(Rn),o=t}}t[n].setWithExplicit("domains",i),o&&t[n].set("selectionExtent",o,!0)}}(e)}function Kp(e,t){const n=e.getScaleComponent(t).get("type"),{encoding:i}=e,o=function(e,t,n,i){if("unaggregated"===e){const{valid:e,reason:i}=im(t,n);if(!e)return void si(i)}else if(void 0===e&&i.useUnaggregatedDomain){const{valid:e}=im(t,n);if(e)return"unaggregated"}return e}(e.scaleDomain(t),e.typedFieldDef(t),n,e.config.scale);return o!==e.scaleDomain(t)&&(e.specifiedScales[t]={...e.specifiedScales[t],domain:o}),"x"===t&&ua(i.x2)?ua(i.x)?Ec(em(n,o,e,"x"),em(n,o,e,"x2"),"domain","scale",om):em(n,o,e,"x2"):"y"===t&&ua(i.y2)?ua(i.y)?Ec(em(n,o,e,"y"),em(n,o,e,"y2"),"domain","scale",om):em(n,o,e,"y2"):em(n,o,e,t)}function Zp(e,t,n){var i;const o=null===(i=Di(n))||void 0===i?void 0:i.unit;return"temporal"===t||o?function(e,t,n){return e.map((e=>{const i=ga(e,{timeUnit:n,type:t});return{signal:"{data: ".concat(i,"}")}}))}(e,t,o):[e]}function em(e,t,n,i){const{encoding:o}=n,r=ua(o[i]),{type:a}=r,s=r.timeUnit;if(function(e){return e&&e.unionWith}(t)){const o=em(e,void 0,n,i),r=Zp(t.unionWith,a,s);return Dc([...o.value,...r])}if(Fi(t))return Dc([t]);if(t&&"unaggregated"!==t&&!xo(t))return Dc(Zp(t,a,s));const c=n.stack;if(c&&i===c.fieldChannel){if("normalize"===c.offset)return Fc([[0,1]]);const e=n.requestDataName(Mc.Main);return Fc([{data:e,field:n.vgField(i,{suffix:"start"})},{data:e,field:n.vgField(i,{suffix:"end"})}])}const u=vn(i)&&qr(r)?function(e,t,n){if(!go(n))return;const i=e.fieldDef(t),o=i.sort;if(Sr(o))return{op:"min",field:vd(i,t),order:"ascending"};const{stack:r}=e,a=r?[...r.groupbyField?[r.groupbyField]:[],...r.stackBy.map((e=>e.fieldDef.field))]:void 0;if(Er(o)){return 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0),Bn(this,"children",[]),Bn(this,"correctDataNames",(e=>(e.from&&e.from.data&&(e.from.data=this.lookupDataSource(e.from.data)),e.from&&e.from.facet&&e.from.facet.data&&(e.from.facet.data=this.lookupDataSource(e.from.facet.data)),e))),this.parent=n,this.config=o,this.view=Oo(a),this.name=null!==(s=e.name)&&void 0!==s?s:i,this.title=xa(e.title)?{text:e.title}:e.title?this.initTitle(e.title):void 0,this.scaleNameMap=n?n.scaleNameMap:new Cm,this.projectionNameMap=n?n.projectionNameMap:new Cm,this.signalNameMap=n?n.signalNameMap:new Cm,this.data=e.data,this.description=e.description,this.transforms=(null!==(c=e.transform)&&void 0!==c?c:[]).map((e=>Tc(e)?{filter:B(e.filter,Wi)}:e)),this.layout="layer"===t||"unit"===t?{}:function(e,t,n){const i=n[t],o={},{spacing:r,columns:a}=i;void 0!==r&&(o.spacing=r),void 0!==a&&(zr(e)&&!Br(e.facet)||Es(e))&&(o.columns=a),Ss(e)&&(o.columns=1);for(const t of Ps)if(void 0!==e[t])if("spacing"===t){var s,c;const n=e[t];o[t]=b(n)?n:{row:null!==(s=n.row)&&void 0!==s?s:r,column:null!==(c=n.column)&&void 0!==c?c:r}}else o[t]=e[t];return o}(e,t,o),this.component={data:{sources:n?n.component.data.sources:[],outputNodes:n?n.component.data.outputNodes:{},outputNodeRefCounts:n?n.component.data.outputNodeRefCounts:{},isFaceted:zr(e)||n&&n.component.data.isFaceted&&void 0===e.data},layoutSize:new Ac,layoutHeaders:{row:{},column:{},facet:{}},mark:null,resolve:{scale:{},axis:{},legend:{},...r?z(r):{}},selection:null,scales:null,projection:null,axes:{},legends:{}}}initTitle(e){const t=J(e),n={text:Aa(e.text)};for(const i of t)n[i]=Aa(e[i]);return n}get width(){return this.getSizeSignalRef("width")}get height(){return this.getSizeSignalRef("height")}parse(){this.parseScale(),this.parseLayoutSize(),this.renameTopLevelLayoutSizeSignal(),this.parseSelections(),this.parseProjection(),this.parseData(),this.parseAxesAndHeaders(),this.parseLegends(),this.parseMarkGroup()}parseScale(){!function(e,{ignoreRange:t}={}){Fm(e),$p(e);for(const t of So)bm(e,t);t||wm(e)}(this)}parseProjection(){cp(this)}renameTopLevelLayoutSizeSignal(){"width"!==this.getName("width")&&this.renameSignal(this.getName("width"),"width"),"height"!==this.getName("height")&&this.renameSignal(this.getName("height"),"height")}parseLegends(){Kd(this)}assembleGroupStyle(){var e,t;if("unit"===this.type||"layer"===this.type)return null!==(e=null===(t=this.view)||void 0===t?void 0:t.style)&&void 0!==e?e:"cell"}assembleEncodeFromView(e){const{style:t,...n}=e,i={};for(const e of J(n)){const t=n[e];void 0!==t&&(i[e]=Fa(t))}return i}assembleGroupEncodeEntry(e){let t={};var n;if((this.view&&(t=this.assembleEncodeFromView(this.view)),!e)&&(this.description&&(t.description=Fa(this.description)),"unit"===this.type||"layer"===this.type))return{width:this.getSizeSignalRef("width"),height:this.getSizeSignalRef("height"),...null!==(n=t)&&void 0!==n?n:{}};return Y(t)?void 0:t}assembleLayout(){if(!this.layout)return;const{spacing:e,...t}=this.layout,{component:n,config:i}=this,o=function(e,t){const n={};for(const i of xt){const o=e[i];if(null==o?void 0:o.facetFieldDef){const{titleAnchor:e,titleOrient:r}=xd(["titleAnchor","titleOrient"],o.facetFieldDef.header,t,i),a=yd(i,r),s=zd(e,a);void 0!==s&&(n[a]=s)}}return Y(n)?void 0:n}(n.layoutHeaders,i);return{padding:e,...this.assembleDefaultLayout(),...t,...o?{titleBand:o}:{}}}assembleDefaultLayout(){return{}}assembleHeaderMarks(){const{layoutHeaders:e}=this.component;let t=[];for(const n of xt)e[n].title&&t.push(Dd(this,n));for(const e of wd)t=t.concat(Cd(this,e));return t}assembleAxes(){return function(e,t){const{x:n=[],y:i=[]}=e;return[...n.map((e=>rd(e,"grid",t))),...i.map((e=>rd(e,"grid",t))),...n.map((e=>rd(e,"main",t))),...i.map((e=>rd(e,"main",t)))].filter((e=>e))}(this.component.axes,this.config)}assembleLegends(){return ip(this)}assembleProjections(){return op(this)}assembleTitle(){var e;const{encoding:t,...n}=null!==(e=this.title)&&void 0!==e?e:{},i={...ba(this.config.title).nonMark,...n,...t?{encode:{update:t}}:{}};if(i.text){var o,r;if(T(["unit","layer"],this.type)){if(T(["middle",void 0],i.anchor))i.frame=null!==(o=i.frame)&&void 0!==o?o:"group"}else i.anchor=null!==(r=i.anchor)&&void 0!==r?r:"start";return Y(i)?void 0:i}}assembleGroup(e=[]){const t={};(e=e.concat(this.assembleSignals())).length>0&&(t.signals=e);const n=this.assembleLayout();n&&(t.layout=n),t.marks=[].concat(this.assembleHeaderMarks(),this.assembleMarks());const i=!this.parent||Sm(this.parent)?cm(this):[];i.length>0&&(t.scales=i);const o=this.assembleAxes();o.length>0&&(t.axes=o);const r=this.assembleLegends();return r.length>0&&(t.legends=r),t}getName(e){return K((this.name?this.name+"_":"")+e)}getDataName(e){return this.getName(Mc[e].toLowerCase())}requestDataName(e){const t=this.getDataName(e),n=this.component.data.outputNodeRefCounts;return n[t]=(n[t]||0)+1,t}getSizeSignalRef(e){if(Sm(this.parent)){const t=on(Td(e)),n=this.component.scales[t];if(n&&!n.merged){const e=n.get("type"),i=n.get("range");if(go(e)&&ki(i)){const e=n.get("name"),i=am(sm(this,t));if(i){return{signal:Md(e,n,Kr({aggregate:"distinct",field:i},{expr:"datum"}))}}return si(Mn(t)),null}}}return{signal:this.signalNameMap.get(this.getName(e))}}lookupDataSource(e){const t=this.component.data.outputNodes[e];return t?t.getSource():e}getSignalName(e){return this.signalNameMap.get(e)}renameSignal(e,t){this.signalNameMap.rename(e,t)}renameScale(e,t){this.scaleNameMap.rename(e,t)}renameProjection(e,t){this.projectionNameMap.rename(e,t)}scaleName(e,t){return t?this.getName(e):zt(e)&&vn(e)&&this.component.scales[e]||this.scaleNameMap.has(this.getName(e))?this.scaleNameMap.get(this.getName(e)):void 0}projectionName(e){return e?this.getName("projection"):this.component.projection&&!this.component.projection.merged||this.projectionNameMap.has(this.getName("projection"))?this.projectionNameMap.get(this.getName("projection")):void 0}getScaleComponent(e){if(!this.component.scales)throw new Error("getScaleComponent cannot be called before parseScale(). Make sure you have called parseScale or use parseUnitModelWithScale().");const t=this.component.scales[e];return t&&!t.merged?t:this.parent?this.parent.getScaleComponent(e):void 0}getSelectionComponent(e,t){let n=this.component.selection[e];if(!n&&this.parent&&(n=this.parent.getSelectionComponent(e,t)),!n)throw new Error('Cannot find a selection named "'.concat(t,'".'));return n}hasAxisOrientSignalRef(){var e,t;return(null===(e=this.component.axes.x)||void 0===e?void 0:e.some((e=>e.hasOrientSignalRef())))||(null===(t=this.component.axes.y)||void 0===t?void 0:t.some((e=>e.hasOrientSignalRef())))}}class Om extends zm{vgField(e,t={}){const n=this.fieldDef(e);if(n)return Kr(n,t)}reduceFieldDef(e,t){return function(e,t,n,i){return e?J(e).reduce(((n,o)=>{const r=e[o];return u(r)?r.reduce(((e,n)=>t.call(i,e,n,o)),n):t.call(i,n,r,o)}),n):n}(this.getMapping(),((t,n,i)=>{const o=ca(n);return o?e(t,o,i):t}),t)}forEachFieldDef(e,t){Ha(this.getMapping(),((t,n)=>{const i=ca(t);i&&e(i,n)}),t)}}class Nm extends Hu{clone(){return new Nm(null,z(this.transform))}constructor(e,t){var n,i,o;super(e),this.transform=t,this.transform=z(t);const r=null!==(n=this.transform.as)&&void 0!==n?n:[void 0,void 0];this.transform.as=[null!==(i=r[0])&&void 0!==i?i:"value",null!==(o=r[1])&&void 0!==o?o:"density"]}dependentFields(){var e;return new Set([this.transform.density,...null!==(e=this.transform.groupby)&&void 0!==e?e:[]])}producedFields(){return new Set(this.transform.as)}hash(){return"DensityTransform ".concat(j(this.transform))}assemble(){const{density:e,...t}=this.transform;return{type:"kde",field:e,...t}}}class Pm extends Hu{clone(){return new Pm(null,{...this.filter})}constructor(e,t){super(e),this.filter=t}static make(e,t){const{config:n,mark:i,markDef:o}=t;if("filter"!==Ba("invalid",o,n))return null;const r=t.reduceFieldDef(((e,n,o)=>{const r=vn(o)&&t.getScaleComponent(o);if(r){vo(r.get("type"))&&"count"!==n.aggregate&&!Jo(i)&&(e[n.field]=n)}return e}),{});return J(r).length?new Pm(e,r):null}dependentFields(){return new Set(J(this.filter))}producedFields(){return new Set}hash(){return"FilterInvalid ".concat(j(this.filter))}assemble(){const e=J(this.filter).reduce(((e,t)=>{const n=this.filter[t],i=Kr(n,{expr:"datum"});return null!==n&&("temporal"===n.type?e.push("(isDate(".concat(i,") || (isValid(").concat(i,") && isFinite(+").concat(i,")))")):"quantitative"===n.type&&(e.push("isValid(".concat(i,")")),e.push("isFinite(+".concat(i,")")))),e}),[]);return e.length>0?{type:"filter",expr:e.join(" && ")}:null}}class jm extends Hu{clone(){return new jm(this.parent,z(this.transform))}constructor(e,t){super(e),this.transform=t,this.transform=z(t);const{flatten:n,as:i=[]}=this.transform;this.transform.as=n.map(((e,t)=>{var n;return null!==(n=i[t])&&void 0!==n?n:e}))}dependentFields(){return new Set(this.transform.flatten)}producedFields(){return new Set(this.transform.as)}hash(){return"FlattenTransform ".concat(j(this.transform))}assemble(){const{flatten:e,as:t}=this.transform;return{type:"flatten",fields:e,as:t}}}class Mm extends Hu{clone(){return new Mm(null,z(this.transform))}constructor(e,t){var n,i,o;super(e),this.transform=t,this.transform=z(t);const r=null!==(n=this.transform.as)&&void 0!==n?n:[void 0,void 0];this.transform.as=[null!==(i=r[0])&&void 0!==i?i:"key",null!==(o=r[1])&&void 0!==o?o:"value"]}dependentFields(){return new Set(this.transform.fold)}producedFields(){return new Set(this.transform.as)}hash(){return"FoldTransform ".concat(j(this.transform))}assemble(){const{fold:e,as:t}=this.transform;return{type:"fold",fields:e,as:t}}}class Tm extends Hu{clone(){return new Tm(null,z(this.fields),this.geojson,this.signal)}static parseAll(e,t){if(t.component.projection&&!t.component.projection.isFit)return e;let n=0;for(const i of[[Ge,He],[Ye,Ve]]){const o=i.map((e=>{const n=ua(t.encoding[e]);return qr(n)?n.field:Wr(n)?{expr:"".concat(n.datum)}:Vr(n)?{expr:"".concat(n.value)}:void 0}));(o[0]||o[1])&&(e=new Tm(e,o,null,t.getName("geojson_".concat(n++))))}if(t.channelHasField($e)){const i=t.typedFieldDef($e);i.type===Vi&&(e=new Tm(e,null,i.field,t.getName("geojson_".concat(n++))))}return e}constructor(e,t,n,i){super(e),this.fields=t,this.geojson=n,this.signal=i}dependentFields(){var e;const t=(null!==(e=this.fields)&&void 0!==e?e:[]).filter(x);return new Set([...this.geojson?[this.geojson]:[],...t])}producedFields(){return new Set}hash(){return"GeoJSON ".concat(this.geojson," ").concat(this.signal," ").concat(j(this.fields))}assemble(){return{type:"geojson",...this.fields?{fields:this.fields}:{},...this.geojson?{geojson:this.geojson}:{},signal:this.signal}}}class Lm extends Hu{clone(){return new Lm(null,this.projection,z(this.fields),z(this.as))}constructor(e,t,n,i){super(e),this.projection=t,this.fields=n,this.as=i}static parseAll(e,t){if(!t.projectionName())return e;for(const n of[[Ge,He],[Ye,Ve]]){const i=n.map((e=>{const n=ua(t.encoding[e]);return qr(n)?n.field:Wr(n)?{expr:"".concat(n.datum)}:Vr(n)?{expr:"".concat(n.value)}:void 0})),o=n[0]===Ye?"2":"";(i[0]||i[1])&&(e=new Lm(e,t.projectionName(),i,[t.getName("x"+o),t.getName("y"+o)]))}return e}dependentFields(){return new Set(this.fields.filter(x))}producedFields(){return new Set(this.as)}hash(){return"Geopoint ".concat(this.projection," ").concat(j(this.fields)," ").concat(j(this.as))}assemble(){return{type:"geopoint",projection:this.projection,fields:this.fields,as:this.as}}}class qm extends Hu{clone(){return new qm(null,z(this.transform))}constructor(e,t){super(e),this.transform=t}dependentFields(){var e;return new Set([this.transform.impute,this.transform.key,...null!==(e=this.transform.groupby)&&void 0!==e?e:[]])}producedFields(){return new Set([this.transform.impute])}processSequence(e){const{start:t=0,stop:n,step:i}=e,o=[t,n,...i?[i]:[]].join(",");return{signal:"sequence(".concat(o,")")}}static makeFromTransform(e,t){return new qm(e,t)}static makeFromEncoding(e,t){const n=t.encoding,i=n.x,o=n.y;if(qr(i)&&qr(o)){const r=i.impute?i:o.impute?o:void 0;if(void 0===r)return;const a=i.impute?o:o.impute?i:void 0,{method:s,value:c,frame:u,keyvals:l}=r.impute,f=Ga(t.mark,n);return new qm(e,{impute:r.field,key:a.field,...s?{method:s}:{},...void 0!==c?{value:c}:{},...u?{frame:u}:{},...void 0!==l?{keyvals:l}:{},...f.length?{groupby:f}:{}})}return null}hash(){return"Impute ".concat(j(this.transform))}assemble(){const{impute:e,key:t,keyvals:n,method:i,groupby:o,value:r,frame:a=[null,null]}=this.transform,s={type:"impute",field:e,key:t,...n?{keyvals:(c=n,void 0!==(null==c?void 0:c.stop)?this.processSequence(n):n)}:{},method:"value",...o?{groupby:o}:{},value:i&&"value"!==i?null:r};var c;if(i&&"value"!==i){return[s,{type:"window",as:["imputed_".concat(e,"_value")],ops:[i],fields:[e],frame:a,ignorePeers:!1,...o?{groupby:o}:{}},{type:"formula",expr:"datum.".concat(e," === null ? datum.imputed_").concat(e,"_value : datum.").concat(e),as:e}]}return[s]}}class Rm extends Hu{clone(){return new Rm(null,z(this.transform))}constructor(e,t){var n,i,o;super(e),this.transform=t,this.transform=z(t);const r=null!==(n=this.transform.as)&&void 0!==n?n:[void 0,void 0];this.transform.as=[null!==(i=r[0])&&void 0!==i?i:t.on,null!==(o=r[1])&&void 0!==o?o:t.loess]}dependentFields(){var e;return new Set([this.transform.loess,this.transform.on,...null!==(e=this.transform.groupby)&&void 0!==e?e:[]])}producedFields(){return new Set(this.transform.as)}hash(){return"LoessTransform ".concat(j(this.transform))}assemble(){const{loess:e,on:t,...n}=this.transform;return{type:"loess",x:t,y:e,...n}}}class Wm extends Hu{clone(){return new Wm(null,z(this.transform),this.secondary)}constructor(e,t,n){super(e),this.transform=t,this.secondary=n}static make(e,t,n,i){const o=t.component.data.sources,{from:r}=n;let a=null;if(function(e){return"data"in e}(r)){let e=nh(r.data,o);e||(e=new Fp(r.data),o.push(e));const n=t.getName("lookup_".concat(i));a=new Gu(e,n,Mc.Lookup,t.component.data.outputNodeRefCounts),t.component.data.outputNodes[n]=a}else if(function(e){return"selection"in e}(r)){const e=r.selection;if(n={as:e,...n},a=t.getSelectionComponent(K(e),e).materialized,!a)throw new Error('Cannot define and lookup the "'.concat(e,'" selection in the same view. ')+"Try moving the lookup into a second, layered view?")}return new Wm(e,n,a.getSource())}dependentFields(){return new Set([this.transform.lookup])}producedFields(){return new Set(this.transform.as?h(this.transform.as):this.transform.from.fields)}hash(){return"Lookup ".concat(j({transform:this.transform,secondary:this.secondary}))}assemble(){let e;if(this.transform.from.fields)e={values:this.transform.from.fields,...this.transform.as?{as:h(this.transform.as)}:{}};else{let t=this.transform.as;x(t)||(si('If "from.fields" is not specified, "as" has to be a string that specifies the key to be used for the data from the secondary source.'),t="_lookup"),e={as:[t]}}return{type:"lookup",from:this.secondary,key:this.transform.from.key,fields:[this.transform.lookup],...e,...this.transform.default?{default:this.transform.default}:{}}}}class Um extends Hu{clone(){return new Um(null,z(this.transform))}constructor(e,t){var n,i,o;super(e),this.transform=t,this.transform=z(t);const r=null!==(n=this.transform.as)&&void 0!==n?n:[void 0,void 0];this.transform.as=[null!==(i=r[0])&&void 0!==i?i:"prob",null!==(o=r[1])&&void 0!==o?o:"value"]}dependentFields(){var e;return new Set([this.transform.quantile,...null!==(e=this.transform.groupby)&&void 0!==e?e:[]])}producedFields(){return new Set(this.transform.as)}hash(){return"QuantileTransform ".concat(j(this.transform))}assemble(){const{quantile:e,...t}=this.transform;return{type:"quantile",field:e,...t}}}class Im extends Hu{clone(){return new Im(null,z(this.transform))}constructor(e,t){var n,i,o;super(e),this.transform=t,this.transform=z(t);const r=null!==(n=this.transform.as)&&void 0!==n?n:[void 0,void 0];this.transform.as=[null!==(i=r[0])&&void 0!==i?i:t.on,null!==(o=r[1])&&void 0!==o?o:t.regression]}dependentFields(){var e;return new Set([this.transform.regression,this.transform.on,...null!==(e=this.transform.groupby)&&void 0!==e?e:[]])}producedFields(){return new Set(this.transform.as)}hash(){return"RegressionTransform ".concat(j(this.transform))}assemble(){const{regression:e,on:t,...n}=this.transform;return{type:"regression",x:t,y:e,...n}}}class Hm extends Hu{clone(){return new Hm(null,z(this.transform))}constructor(e,t){super(e),this.transform=t}addDimensions(e){var t;this.transform.groupby=U((null!==(t=this.transform.groupby)&&void 0!==t?t:[]).concat(e),(e=>e))}producedFields(){}dependentFields(){var e;return new Set([this.transform.pivot,this.transform.value,...null!==(e=this.transform.groupby)&&void 0!==e?e:[]])}hash(){return"PivotTransform ".concat(j(this.transform))}assemble(){const{pivot:e,value:t,groupby:n,limit:i,op:o}=this.transform;return{type:"pivot",field:e,value:t,...void 0!==i?{limit:i}:{},...void 0!==o?{op:o}:{},...void 0!==n?{groupby:n}:{}}}}class Gm extends Hu{clone(){return new Gm(null,z(this.transform))}constructor(e,t){super(e),this.transform=t}dependentFields(){return new Set}producedFields(){return new Set}hash(){return"SampleTransform ".concat(j(this.transform))}assemble(){return{type:"sample",size:this.transform.sample}}}function Vm(e){let t=0;return function n(i,o){if(i instanceof Fp&&!i.isGenerator&&!Bc(i.data)){e.push(o);o={name:null,source:o.name,transform:[]}}var r;if(i instanceof xp&&(i.parent instanceof Fp&&!o.source?(o.format={...null!==(r=o.format)&&void 0!==r?r:{},parse:i.assembleFormatParse()},o.transform.push(...i.assembleTransforms(!0))):o.transform.push(...i.assembleTransforms())),i instanceof gp){o.name||(o.name="data_".concat(t++)),!o.source||o.transform.length>0?(e.push(o),i.data=o.name):i.data=o.source;for(const t of i.assemble())e.push(t)}else{if((i instanceof Ap||i instanceof Dp||i instanceof Pm||i instanceof ed||i instanceof gd||i instanceof Lm||i instanceof Tm||i instanceof hp||i instanceof Wm||i instanceof Ip||i instanceof Wp||i instanceof Mm||i instanceof jm||i instanceof Nm||i instanceof Rm||i instanceof Um||i instanceof Im||i instanceof wp||i instanceof 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of Zt){const o=this.child.component.scales[i];if(o&&!o.merged){const r=o.get("type"),a=o.get("range");if(go(r)&&ki(a)){const o=am(sm(this.child,i));o?(e.push(o),t.push("distinct"),n.push("distinct_".concat(o))):si(Mn(i))}}}return{fields:e,ops:t,as:n}}assembleFacet(){const{name:e,data:t}=this.component.data.facetRoot,{row:n,column:i}=this.facet,{fields:o,ops:r,as:a}=this.getCardinalityAggregateForChild(),s=[];for(const e of xt){const t=this.facet[e];if(t){s.push(Kr(t));const{bin:c,sort:l}=t;if(Fn(c)&&s.push(Kr(t,{binSuffix:"end"})),Er(l)){const{field:e,op:s=Dr}=l,c=eh(t,l);n&&i?(o.push(c),r.push("max"),a.push(c)):(o.push(e),r.push(s),a.push(c))}else if(u(l)){const n=vd(t,e);o.push(n),r.push("max"),a.push(n)}}}const c=!!n&&!!i;return{name:e,data:t,groupby:s,...c||o.length>0?{aggregate:{...c?{cross:c}:{},...o.length?{fields:o,ops:r,as:a}:{}}}:{}}}facetSortFields(e){const{facet:t}=this,n=t[e];return 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t}(this.component.data.facetRoot),n=e.assembleGroupEncodeEntry(!1),i=this.assembleLabelTitle()||e.assembleTitle(),o=e.assembleGroupStyle();return[{name:this.getName("cell"),type:"group",...i?{title:i}:{},...o?{style:o}:{},from:{facet:this.assembleFacet()},sort:{field:xt.map((e=>this.facetSortFields(e))).flat(),order:xt.map((e=>this.facetSortOrder(e))).flat()},...t.length>0?{data:t}:{},...n?{encode:{update:n}}:{},...e.assembleGroup(ml(this,[]))}]}getMapping(){return this.facet}}function nh(e,t){for(const a of t){var n,i,o,r;const t=a.data;if(e.name&&a.hasName()&&e.name!==a.dataName)continue;const s=null===(n=e.format)||void 0===n?void 0:n.mesh,c=null===(i=t.format)||void 0===i?void 0:i.feature;if(s&&c)continue;const u=null===(o=e.format)||void 0===o?void 0:o.feature;if((u||c)&&u!==c)continue;const l=null===(r=t.format)||void 0===r?void 0:r.mesh;if(!s&&!l||s===l)if(_c(e)&&_c(t)){if(_(e.values,t.values))return a}else if(Bc(e)&&Bc(t)){if(e.url===t.url)return a}else if(zc(e)&&e.name===a.dataName)return a}return null}function ih(e){var t,n,i;let o=function(e,t){if(e.data||!e.parent){if(null===e.data){const e=new Fp({values:[]});return t.push(e),e}const n=nh(e.data,t);if(n)return Oc(e.data)||(n.data.format=R({},e.data.format,n.data.format)),!n.hasName()&&e.data.name&&(n.dataName=e.data.name),n;{const n=new Fp(e.data);return t.push(n),n}}return e.parent.component.data.facetRoot?e.parent.component.data.facetRoot:e.parent.component.data.main}(e,e.component.data.sources);const{outputNodes:r,outputNodeRefCounts:a}=e.component.data,s=e.parent?e.parent.component.data.ancestorParse.clone():new Sc,c=e.data;Oc(c)?(Nc(c)?o=new Dp(o,c.sequence):jc(c)&&(o=new Ap(o,c.graticule)),s.parseNothing=!0):null===(null==c||null===(t=c.format)||void 0===t?void 0:t.parse)&&(s.parseNothing=!0),o=null!==(n=xp.makeExplicit(o,e,s))&&void 0!==n?n:o,o=new wp(o);const u=e.parent&&_m(e.parent);var l;(Em(e)||Sm(e))&&(u&&(o=null!==(l=pp.makeFromEncoding(o,e))&&void 0!==l?l:o));e.transforms.length>0&&(o=function(e,t,n){let i=0;for(const a of t.transforms){let s,c=void 0;if(Jc(a))s=e=new gd(e,a),c="derived";else if(Tc(a)){var o;const i=yp(a);s=e=null!==(o=xp.makeWithAncestors(e,{},i,n))&&void 0!==o?o:e,e=new ed(e,t,a.filter)}else if(Xc(a))s=e=pp.makeFromTransform(e,a,t),c="number";else if($c(a))c="date",void 0===n.getWithExplicit(a.field).value&&(e=new xp(e,{[a.field]:c}),n.set(a.field,c,!1)),s=e=Vu.makeFromTransform(e,a);else if(Kc(a))s=e=hp.makeFromTransform(e,a),c="number",zl(t)&&(e=new wp(e));else if(Lc(a))s=e=Wm.make(e,t,a,i++),c="derived";else if(Gc(a))s=e=new Ip(e,a),c="number";else if(Vc(a))s=e=new Wp(e,a),c="number";else if(Zc(a))s=e=Up.makeFromTransform(e,a),c="derived";else if(eu(a))s=e=new Mm(e,a),c="derived";else if(Yc(a))s=e=new jm(e,a),c="derived";else if(qc(a))s=e=new Hm(e,a),c="derived";else if(Hc(a))e=new Gm(e,a);else if(Qc(a))s=e=qm.makeFromTransform(e,a),c="derived";else if(Rc(a))s=e=new Nm(e,a),c="derived";else if(Wc(a))s=e=new Um(e,a),c="derived";else if(Uc(a))s=e=new Im(e,a),c="derived";else{if(!Ic(a)){si("Ignoring an invalid transform: ".concat(P(a),"."));continue}s=e=new Rm(e,a),c="derived"}if(s&&void 0!==c)for(const e of null!==(r=s.producedFields())&&void 0!==r?r:[]){var r;n.set(e,c,!1)}}return e}(o,e,s));const f=function(e){const t={};if(Em(e)&&e.component.selection)for(const n of J(e.component.selection)){const i=e.component.selection[n];for(const e of i.project.items)!e.channel&&ce(e.field)>1&&(t[e.field]="flatten")}return t}(e),d=bp(e);if(o=null!==(i=xp.makeWithAncestors(o,{},{...f,...d},s))&&void 0!==i?i:o,Em(e)&&(o=Tm.parseAll(o,e),o=Lm.parseAll(o,e)),Em(e)||Sm(e)){var p,m;if(!u)o=null!==(m=pp.makeFromEncoding(o,e))&&void 0!==m?m:o;o=null!==(p=Vu.makeFromEncoding(o,e))&&void 0!==p?p:o,o=gd.parseAllForSortIndex(o,e)}const h=e.getDataName(Mc.Raw),g=new Gu(o,h,Mc.Raw,a);if(r[h]=g,o=g,Em(e)){var v,y;const t=hp.makeFromEncoding(o,e);t&&(o=t,zl(e)&&(o=new wp(o))),o=null!==(v=qm.makeFromEncoding(o,e))&&void 0!==v?v:o,o=null!==(y=Up.makeFromEncoding(o,e))&&void 0!==y?y:o}var b;Em(e)&&(o=null!==(b=Pm.make(o,e))&&void 0!==b?b:o);const x=e.getDataName(Mc.Main),w=new Gu(o,x,Mc.Main,a);r[x]=w,o=w,Em(e)&&function(e,t){Bl(e,(n=>{const i=n.name,o=e.getName("lookup_".concat(i));e.component.data.outputNodes[o]=n.materialized=new Gu(new ed(t,e,{selection:i}),o,Mc.Lookup,e.component.data.outputNodeRefCounts)}))}(e,w);let A=null;if(Sm(e)){var D;const t=e.getName("facet");o=null!==(D=function(e,t){const{row:n,column:i}=t;if(n&&i){let t=null;for(const o of[n,i])if(Er(o.sort)){const{field:n,op:i=Dr}=o.sort;e=t=new Wp(e,{joinaggregate:[{op:i,field:n,as:eh(o,o.sort,{forAs:!0})}],groupby:[Kr(o)]})}return t}return null}(o,e.facet))&&void 0!==D?D:o,A=new gp(o,e,t,w.getSource()),r[t]=A}return{...e.component.data,outputNodes:r,outputNodeRefCounts:a,raw:g,main:w,facetRoot:A,ancestorParse:s}}class oh extends zm{constructor(e,t,n,i){var o,r,a,s;super(e,"concat",t,n,i,e.resolve),Bn(this,"children",void 0),"shared"!==(null===(o=e.resolve)||void 0===o||null===(r=o.axis)||void 0===r?void 0:r.x)&&"shared"!==(null===(a=e.resolve)||void 0===a||null===(s=a.axis)||void 0===s?void 0:s.y)||si("Axes cannot be shared in concatenated or repeated views yet (https://github.com/vega/vega-lite/issues/2415)."),this.children=this.getChildren(e).map(((e,t)=>Eh(e,this,this.getName("concat_"+t),void 0,i)))}parseData(){this.component.data=ih(this);for(const e of this.children)e.parseData()}parseSelections(){this.component.selection={};for(const e of this.children){e.parseSelections();for(const t of J(e.component.selection))this.component.selection[t]=e.component.selection[t]}}parseMarkGroup(){for(const e of this.children)e.parseMarkGroup()}parseAxesAndHeaders(){for(const e of this.children)e.parseAxesAndHeaders()}getChildren(e){return Ss(e)?e.vconcat:Bs(e)?e.hconcat:e.concat}parseLayoutSize(){!function(e){$m(e);const t=1===e.layout.columns?"width":"childWidth",n=void 0===e.layout.columns?"height":"childHeight";Km(e,t),Km(e,n)}(this)}parseAxisGroup(){return null}assembleSelectionTopLevelSignals(e){return this.children.reduce(((e,t)=>t.assembleSelectionTopLevelSignals(e)),e)}assembleSignals(){return this.children.forEach((e=>e.assembleSignals())),[]}assembleLayoutSignals(){const e=Nd(this);for(const t of this.children)e.push(...t.assembleLayoutSignals());return e}assembleSelectionData(e){return this.children.reduce(((e,t)=>t.assembleSelectionData(e)),e)}assembleMarks(){return this.children.map((e=>{const t=e.assembleTitle(),n=e.assembleGroupStyle(),i=e.assembleGroupEncodeEntry(!1);return{type:"group",name:e.getName("group"),...t?{title:t}:{},...n?{style:n}:{},...i?{encode:{update:i}}:{},...e.assembleGroup()}}))}assembleDefaultLayout(){const e=this.layout.columns;return{...null!=e?{columns:e}:{},bounds:"full",align:"each"}}}const rh={disable:1,gridScale:1,scale:1,...xe,labelExpr:1,encode:1},ah=J(rh);class sh extends Ac{constructor(e={},t={},n=!1){super(),this.explicit=e,this.implicit=t,this.mainExtracted=n}clone(){return new sh(z(this.explicit),z(this.implicit),this.mainExtracted)}hasAxisPart(e){return"axis"===e||("grid"===e||"title"===e?!!this.get(e):!(!1===(t=this.get(e))||null===t));var t}hasOrientSignalRef(){return Fi(this.explicit.orient)}}const ch={bottom:"top",top:"bottom",left:"right",right:"left"};function uh(e,t){if(!e)return t.map((e=>e.clone()));{if(e.length!==t.length)return;const n=e.length;for(let i=0;i<n;i++){const n=e[i],o=t[i];if(!!n!=!!o)return;if(n&&o){const t=n.getWithExplicit("orient"),r=o.getWithExplicit("orient");if(t.explicit&&r.explicit&&t.value!==r.value)return;e[i]=lh(n,o)}}}return e}function lh(e,t){for(const n of ah){const i=Ec(e.getWithExplicit(n),t.getWithExplicit(n),n,"axis",((e,t)=>{switch(n){case"title":return 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0===Ba("opacity",i,n)&&(i.opacity=function(e,t){if(T([qo,Io,Go,Vo],e)&&!Ra(t))return.7;return}(i.type,t));return void 0===Ba("cursor",i,n)&&(i.cursor=function(e,t,n){if(t.href||e.href||Ba("href",e,n))return"pointer";return e.cursor}(i,t,n)),i}function hh(e,t){const{config:n}=e;return{...Tu(e,{align:"ignore",baseline:"ignore",color:"include",size:"include",orient:"ignore",theta:"ignore"}),...Fu("x",e,{defaultPos:"mid"}),...Fu("y",e,{defaultPos:"mid"}),...xu("size",e),...xu("angle",e),...gh(e,n,t)}}function gh(e,t,n){return n?{shape:{value:n}}:xu("shape",e)}function vh(e,t,n){if(void 0===Ba("align",e,n))return"center"}function yh(e,t,n){if(void 0===Ba("baseline",e,n))return"middle"}function bh(e){var t;const{config:n,markDef:i}=e,{orient:o}=i,r="horizontal"===o?"width":"height",a=e.getScaleComponent("horizontal"===o?"x":"y"),s=null!==(t=Ba("size",i,n,{vgChannel:r}))&&void 0!==t?t:n.tick.bandSize;if(void 0!==s)return s;{const e=a?a.get("range"):void 0;if(e&&ki(e)&&b(e.step))return 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e.encoding.x||e.encoding.y||e.encoding.latitude||e.encoding.longitude?{...Tu(e,{align:"ignore",baseline:"ignore",color:"include",orient:"ignore",size:"ignore",theta:"ignore"}),...Bu("x",e,{defaultPos:"horizontal"===n?"zeroOrMax":"mid",defaultPos2:"zeroOrMin",range:"vertical"!==n}),...Bu("y",e,{defaultPos:"vertical"===n?"zeroOrMax":"mid",defaultPos2:"zeroOrMin",range:"horizontal"!==n}),...xu("size",e,{vgChannel:"strokeWidth"})}:{}}},square:{vgMark:"symbol",encodeEntry:e=>hh(e,"square")},text:{vgMark:"text",encodeEntry:e=>{const{config:t,encoding:n}=e;return{...Tu(e,{align:"include",baseline:"include",color:"include",size:"ignore",orient:"ignore",theta:"include"}),...Fu("x",e,{defaultPos:"mid"}),...Fu("y",e,{defaultPos:"mid"}),...du(e),...xu("size",e,{vgChannel:"fontSize"}),...xu("angle",e),...Wu("align",vh(e.markDef,n,t)),...Wu("baseline",yh(e.markDef,n,t)),...Fu("radius",e,{defaultPos:null,isMidPoint:!0}),...Fu("theta",e,{defaultPos:null,isMidPoint:!0})}}},tick:{vgMark:"rect",encodeEntry:e=>{const{config:t,markDef:n}=e,i=n.orient,o="horizontal"===i?"width":"height",r="horizontal"===i?"height":"width";return{...Tu(e,{align:"ignore",baseline:"ignore",color:"include",orient:"ignore",size:"ignore",theta:"ignore"}),...Fu("x",e,{defaultPos:"mid",vgChannel:"xc"}),...Fu("y",e,{defaultPos:"mid",vgChannel:"yc"}),...xu("size",e,{defaultValue:bh(e),vgChannel:o}),[r]:Fa(Ba("thickness",n,t))}}},trail:{vgMark:"trail",encodeEntry:e=>({...Tu(e,{align:"ignore",baseline:"ignore",color:"include",size:"include",orient:"ignore",theta:"ignore"}),...Fu("x",e,{defaultPos:"mid"}),...Fu("y",e,{defaultPos:"mid"}),...xu("size",e),...Ru(e)})}};function wh(e){if(T([Lo,jo,Ho],e.mark)){const t=Ga(e.mark,e.encoding);if(t.length>0)return function(e,t){return[{name:e.getName("pathgroup"),type:"group",from:{facet:{name:Ah+e.requestDataName(Mc.Main),data:e.requestDataName(Mc.Main),groupby:t}},encode:{update:{width:{field:{group:"width"}},height:{field:{group:"height"}}}},marks:Fh(e,{fromPrefix:Ah})}]}(e,t)}else if(T([Mo],e.mark)){const t=Bi.some((t=>Ba(t,e.markDef,e.config)));if(e.stack&&!e.fieldDef("size")&&t)return function(e){const[t]=Fh(e,{fromPrefix:Dh}),n=e.scaleName(e.stack.fieldChannel),i=(t={})=>e.vgField(e.stack.fieldChannel,t),o=(e,t)=>{const o=[i({prefix:"min",suffix:"start",expr:t}),i({prefix:"max",suffix:"start",expr:t}),i({prefix:"min",suffix:"end",expr:t}),i({prefix:"max",suffix:"end",expr:t})];return"".concat(e,"(").concat(o.map((e=>"scale('".concat(n,"',").concat(e,")"))).join(","),")")};let r,a;"x"===e.stack.fieldChannel?(r={...O(t.encode.update,["y","yc","y2","height",...Bi]),x:{signal:o("min","datum")},x2:{signal:o("max","datum")},clip:{value:!0}},a={x:{field:{group:"x"},mult:-1},height:{field:{group:"height"}}},t.encode.update={...N(t.encode.update,["y","yc","y2"]),height:{field:{group:"height"}}}):(r={...O(t.encode.update,["x","xc","x2","width"]),y:{signal:o("min","datum")},y2:{signal:o("max","datum")},clip:{value:!0}},a={y:{field:{group:"y"},mult:-1},width:{field:{group:"width"}}},t.encode.update={...N(t.encode.update,["x","xc","x2"]),width:{field:{group:"width"}}});for(const n of Bi){const i=_a(n,e.markDef,e.config);t.encode.update[n]?(r[n]=t.encode.update[n],delete t.encode.update[n]):i&&(r[n]=Fa(i)),i&&(t.encode.update[n]={value:0})}const s=e.fieldDef(e.stack.groupbyChannel),c=Kr(s)?[Kr(s)]:[];((null==s?void 0:s.bin)||(null==s?void 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0}(e),function(e){const t=e.component.projection;return!(!t||t.isFit)||void 0}(e)),s=Sa(i),c=o.key,l=function(e){const{encoding:t,stack:n,mark:i,markDef:o,config:r}=e,a=t.order;if(!(!u(a)&&Vr(a)&&M(a.value)||!a&&M(Ba("order",o,r)))){if((u(a)||qr(a))&&!n)return Na(a,{expr:"datum"});if(Jo(i)){const n="horizontal"===o.orient?"y":"x",i=t[n];if(qr(i)){const t=i.sort;return u(t)?{field:Kr(i,{prefix:n,suffix:"sort_index",expr:"datum"})}:Er(t)?{field:Kr({aggregate:Ra(e.encoding)?t.op:void 0,field:t.field},{expr:"datum"})}:Cr(t)?{field:Kr(e.fieldDef(t.encoding),{expr:"datum"}),order:t.order}:null===t?void 0:{field:Kr(i,{binSuffix:e.stack&&e.stack.impute?"mid":void 0,expr:"datum"})}}}}}(e),f=function(e){if(!e.component.selection)return null;const t=J(e.component.selection).length;let n=t,i=e.parent;for(;i&&0===n;)n=J(i.component.selection).length,i=i.parent;return n?{interactive:t>0||!!e.encoding.tooltip}:null}(e),d=Ba("aria",i,r),p=xh[n].postEncodingTransform?xh[n].postEncodingTransform(e):null;return[{name:e.getName("marks"),type:xh[n].vgMark,...a?{clip:!0}:{},...s?{style:s}:{},...c?{key:c.field}:{},...l?{sort:l}:{},...f||{},...!1===d?{aria:d}:{},from:{data:t.fromPrefix+e.requestDataName(Mc.Main)},encode:{update:xh[n].encodeEntry(e)},...p?{transform:p}:{}}]}class kh extends Om{constructor(e,t,n,i={},o){super(e,"unit",t,n,o,void 0,Ns(e)?e.view:void 0),Bn(this,"markDef",void 0),Bn(this,"encoding",void 0),Bn(this,"specifiedScales",{}),Bn(this,"stack",void 0),Bn(this,"specifiedAxes",{}),Bn(this,"specifiedLegends",{}),Bn(this,"specifiedProjection",{}),Bn(this,"selection",{}),Bn(this,"children",[]);const r=$o(e.mark)?{...e.mark}:{type:e.mark},a=r.type;void 0===r.filled&&(r.filled=function(e,t,{graticule:n}){if(n)return!1;const i=_a("filled",e,t),o=e.type;return ue(i,o!==qo&&o!==Lo&&o!==Wo)}(r,o,{graticule:e.data&&jc(e.data)}));const s=this.encoding=Ua(e.encoding||{},a,r.filled,o);this.markDef=mh(r,s,o),this.size=function({encoding:e,size:t}){for(const n of Zt){const i=Tt(n);Os(t[i])&&Ur(e[n])&&(delete t[i],si(ei(i)))}return t}({encoding:s,size:Ns(e)?{...i,...e.width?{width:e.width}:{},...e.height?{height:e.height}:{}}:i}),this.stack=nc(a,s),this.specifiedScales=this.initScales(a,s),this.specifiedAxes=this.initAxes(s),this.specifiedLegends=this.initLegends(s),this.specifiedProjection=e.projection,this.selection=e.selection}get hasProjection(){const{encoding:e}=this,t=this.mark===Yo,n=e&&gt.some((t=>Hr(e[t])));return t||n}scaleDomain(e){const t=this.specifiedScales[e];return t?t.domain:void 0}axis(e){return this.specifiedAxes[e]}legend(e){return this.specifiedLegends[e]}initScales(e,t){return gn.reduce(((e,n)=>{const i=ua(t[n]);var o;i&&(e[n]=this.initScale(null!==(o=i.scale)&&void 0!==o?o:{}));return e}),{})}initScale(e){const{domain:t,range:n}=e,i=Oo(e);return u(t)&&(i.domain=t.map(Aa)),u(n)&&(i.range=n.map(Aa)),i}initAxes(e){return Zt.reduce(((t,n)=>{const i=e[n];if(Hr(i)||n===Me&&Hr(e.x2)||n===Te&&Hr(e.y2)){const e=Hr(i)?i.axis:void 0;t[n]=e?this.initAxis({...e}):e}return t}),{})}initAxis(e){const t=J(e),n={};for(const i of t){const t=e[i];n[i]=ve(t)?wa(t):Aa(t)}return n}initLegends(e){return mn.reduce(((t,n)=>{const i=ua(e[n]);if(i&&function(e){switch(e){case Je:case Xe:case Qe:case Ke:case $e:case et:case it:case ot:return!0;case tt:case nt:case Ze:return!1}}(n)){const e=i.legend;t[n]=e?Oo(e):e}return t}),{})}parseData(){this.component.data=ih(this)}parseLayoutSize(){!function(e){const{size:t,component:n}=e;for(const i of Zt){const o=Tt(i);if(t[o]){const e=t[o];n.layoutSize.set(o,Os(e)?"step":e,!0)}else{const t=Zm(e,o);n.layoutSize.set(o,t,!1)}}}(this)}parseSelections(){this.component.selection=function(e,t){const n={},i=e.config.selection;for(const r of J(null!=t?t:{})){const a=z(t[r]),{fields:s,encodings:c,...u}=i[a.type];for(const e 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+/*!
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+
+        </script>
+        <style>
+            .custom-pill {
+                color: #54785a;
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+            .custom-pill a:hover {
+                color: darkgrey;
+            }
+            .custom-pill .active {
+                background-color: #54785a !important;
+            }
+        </style>
+    </head>
+    <body>
+        <nav class="navbar navbar-expand-lg navbar-dark" style="background-color: #54785a;">
+            <a class="navbar-brand" href="#">fastqc-rs report</a>
+            <div class="collapse navbar-collapse" id="navbarText">
+                <ul class="navbar-nav mr-auto">
+                    <li class="nav-item">
+                        <a class="nav-link">version 0.3.4</a>
+                    </li>
+                    <li class="nav-item">
+                        <a class="nav-link" href="hhttps://github.com/fxwiegand/fastqc-rs">github</a>
+                    </li>
+                </ul>
+                <span class="navbar-text">
+                    created Fri May 30 14:53:58 2025
+                </span>
+            </div>
+        </nav>
+        <nav aria-label="breadcrumb">
+            <ol class="breadcrumb" style="background-color: lightgrey;">
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+        
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+                        // Embed the visualization in the container with id `vis`
+                        vegaEmbed('#count-div', countSpec);
+                        </script>
+                    </div>
+                    
+                    <div class="tab-pane fade show " id="v-pills-rlen" role="tabpanel" aria-labelledby="v-pills-rlen-tab">
+                        <div id="rlen-div"></div>
+                        <script>
+                        var rlenSpec = {"$schema":"https://vega.github.io/schema/vega-lite/v4.json","data":{"values":[{"count":200,"length":101}]},"description":"Read lengths distribution","encoding":{"color":{"value":"#54785a"},"x":{"field":"count","type":"quantitative"},"y":{"axis":{"labelAngle":0},"field":"length","type":"nominal"}},"mark":"bar","title":"Read lengths distribution"};
+                        // Embed the visualization in the container with id `vis`
+                        vegaEmbed('#rlen-div', rlenSpec);
+                        </script>
+                    </div>
+                    
+                    <div class="tab-pane fade show " id="v-pills-qual" role="tabpanel" aria-labelledby="v-pills-qual-tab">
+                        <div id="qual-div"></div>
+                        <script>
+                        var qualSpec = {"$schema":"https://vega.github.io/schema/vega-lite/v4.json","data":{"values":[{"count":5,"score":32},{"count":3,"score":29},{"count":7,"score":26},{"count":1,"score":23},{"count":1,"score":20},{"count":49,"score":37},{"count":9,"score":34},{"count":5,"score":31},{"count":1,"score":28},{"count":1,"score":25},{"count":6,"score":39},{"count":33,"score":36},{"count":10,"score":33},{"count":6,"score":30},{"count":5,"score":27},{"count":1,"score":24},{"count":41,"score":38},{"count":16,"score":35}]},"description":"Sequence quality scores","encoding":{"color":{"value":"#54785a"},"x":{"field":"score","title":"Phred score","type":"quantitative"},"y":{"field":"count","title":"Occurrences of mean read qualities","type":"quantitative"}},"mark":{"interpolate":"basis","type":"line"},"title":"Sequence quality scores","width":500};
+                        // Embed the visualization in the container with id `vis`
+                        vegaEmbed('#qual-div', qualSpec);
+                        </script>
+                    </div>
+                    
+                </div>
+            </div>
+            <div class="col-2" style="overflow: auto">
+                <table class="table table-sm">
+                    
+                        <tr>
+                            <th>
+                                average GC content
+                            </th>
+                            <td>
+                                46.15999984741211
+                            </td>
+                        </tr>
+                    
+                        <tr>
+                            <th>
+                                average read length
+                            </th>
+                            <td>
+                                101
+                            </td>
+                        </tr>
+                    
+                        <tr>
+                            <th>
+                                canonical
+                            </th>
+                            <td>
+                                True
+                            </td>
+                        </tr>
+                    
+                        <tr>
+                            <th>
+                                file name
+                            </th>
+                            <td>
+                                example.fastq
+                            </td>
+                        </tr>
+                    
+                        <tr>
+                            <th>
+                                k
+                            </th>
+                            <td>
+                                5
+                            </td>
+                        </tr>
+                    
+                        <tr>
+                            <th>
+                                total reads
+                            </th>
+                            <td>
+                                200
+                            </td>
+                        </tr>
+                    
+                </table>
+            </div>
+        </div>
+    </body>
+</html>
\ No newline at end of file
diff --git a/polars_bio/__init__.py b/polars_bio/__init__.py
index 01d66d58..ffe5dce6 100644
--- a/polars_bio/__init__.py
+++ b/polars_bio/__init__.py
@@ -1,5 +1,6 @@
 from polars_bio.polars_bio import InputFormat, ReadOptions, VcfReadOptions
 
+from .base_sequnce_quality_vis import visualize_base_sequence_quality
 from .context import ctx, set_option
 from .io import (
     describe_vcf,
@@ -16,6 +17,7 @@
 from .polars_ext import PolarsRangesOperations as LazyFrame
 from .range_op import FilterOp, count_overlaps, coverage, merge, nearest, overlap
 from .range_viz import visualize_intervals
+from .quality_stats import base_sequence_quality
 
 POLARS_BIO_MAX_THREADS = "datafusion.execution.target_partitions"
 
@@ -29,6 +31,7 @@
     "coverage",
     "ctx",
     "FilterOp",
+    "visualize_base_sequence_quality",
     "visualize_intervals",
     "read_bam",
     "read_vcf",
@@ -45,4 +48,5 @@
     "ReadOptions",
     "VcfReadOptions",
     "set_option",
+    "base_sequence_quality",
 ]
diff --git a/polars_bio/base_sequnce_quality_vis.py b/polars_bio/base_sequnce_quality_vis.py
new file mode 100644
index 00000000..fd6cd51b
--- /dev/null
+++ b/polars_bio/base_sequnce_quality_vis.py
@@ -0,0 +1,51 @@
+from typing import Union
+
+import pandas as pd
+import polars as pl
+from matplotlib import pyplot as plt
+
+
+def visualize_base_sequence_quality(df: Union[pd.DataFrame, pl.DataFrame]) -> None:
+    """
+    Visualize the overlapping intervals.
+
+    Parameters:
+        df: Pandas DataFrame or Polars DataFrame. The DataFrame containing the base sequence quality results
+    """
+    assert isinstance(
+        df, (pd.DataFrame, pl.DataFrame)
+    ), "df must be a Pandas or Polars DataFrame"
+    df = df if isinstance(df, pd.DataFrame) else df.to_pandas()
+    df = df.sort_values(by="pos")
+
+    boxes = [
+        {
+            "label": int(row["pos"]),
+            "whislo": row["lower"],
+            "q1": row["q1"],
+            "med": row["median"],
+            "q3": row["q3"],
+            "whishi": row["upper"],
+        }
+        for _, row in df.iterrows()
+    ]
+
+    fig, ax = plt.subplots()
+    fig.set_size_inches(15, 5)
+
+    plot = ax.plot(df["pos"] + 1, df["avg"])
+    box_plot = ax.bxp(boxes, showfliers=False)
+
+    ax.set_title("base sequence quality")
+    ax.set_ylabel("Phred score")
+    ax.set_xlabel("Position in read (bp)")
+
+    ax.legend(
+        [plot[0], box_plot["medians"][0]],
+        ["Average of phred score", "Median of phred score"],
+    )
+
+    for label in ax.get_xticklabels():
+        label.set_fontsize(6)
+
+    plt.show()
diff --git a/polars_bio/quality_stats.py b/polars_bio/quality_stats.py
new file mode 100644
index 00000000..cc1a1be2
--- /dev/null
+++ b/polars_bio/quality_stats.py
@@ -0,0 +1,59 @@
+from pathlib import Path
+from typing import Union
+import datafusion
+import polars as pl
+import pandas as pd
+import pyarrow as pa
+from .context import ctx
+from polars_bio.polars_bio import (
+    base_sequance_quality_scan,
+    base_sequance_quality_frame,
+)
+
+
+def base_sequence_quality(
+    df: Union[str, Path, pl.DataFrame, pl.LazyFrame, pd.DataFrame],
+    quality_scores_column: str = "quality_scores",
+    output_type: str = "polars.DataFrame",
+) -> Union[pl.DataFrame, pd.DataFrame]:
+    """
+    Compute base sequence quality statistics from various dataframe/file types.
+
+    Args:
+        df: Input data as a file path or dataframe.
+        quality_scores_column: Name of the column with quality scores.
+        output_type: Output type, either "polars.DataFrame" or "pandas.DataFrame".
+
+    Returns:
+        DataFrame with base sequence quality statistics.
+    """
+    if isinstance(df, (str, Path)):
+        df = str(df)
+        supported_exts = {".parquet", ".csv", ".bed", ".vcf", ".fastq"}
+        ext = set(Path(df).suffixes)
+        if not (supported_exts & ext or not ext):
+            raise ValueError(
+                "Input file must be a Parquet, CSV, BED, VCF, or FASTQ file."
+            )
+        result: datafusion.DataFrame = base_sequance_quality_scan(
+            ctx, df, quality_scores_column
+        )
+    else:
+        if isinstance(df, pl.LazyFrame):
+            arrow_table = df.collect().to_arrow()
+        elif isinstance(df, pl.DataFrame):
+            arrow_table = df.to_arrow()
+        elif isinstance(df, pd.DataFrame):
+            arrow_table = pa.Table.from_pandas(df)
+        else:
+            raise TypeError("Unsupported dataframe type.")
+        result: datafusion.DataFrame = base_sequance_quality_frame(
+            ctx, arrow_table, quality_scores_column
+        )
+
+    if output_type == "polars.DataFrame":
+        return result.to_polars()
+    elif output_type == "pandas.DataFrame":
+        return result.to_pandas()
+    else:
+        raise ValueError("output_type must be 'polars.DataFrame' or 'pandas.DataFrame'")
diff --git a/src/context.rs b/src/context.rs
index 5f47f30e..1525ef05 100644
--- a/src/context.rs
+++ b/src/context.rs
@@ -25,7 +25,6 @@ impl PyBioSessionContext {
     pub fn new(seed: String, catalog_dir: String) -> PyResult<Self> {
         let ctx = create_context().unwrap();
         let session_config: HashMap<String, String> = HashMap::new();
-
         Ok(PyBioSessionContext {
             ctx,
             session_config,
diff --git a/src/lib.rs b/src/lib.rs
index c8890a8d..152b0736 100644
--- a/src/lib.rs
+++ b/src/lib.rs
@@ -1,6 +1,8 @@
+mod sequence_quality_histogram;
 mod context;
 mod operation;
 mod option;
+mod quantile_stats;
 mod query;
 mod scan;
 mod streaming;
@@ -16,6 +18,7 @@ use datafusion::datasource::MemTable;
 use datafusion_python::dataframe::PyDataFrame;
 use datafusion_vcf::storage::VcfReader;
 use log::{debug, error, info};
+use operation::do_base_sequence_quality;
 use polars_lazy::prelude::{LazyFrame, ScanArgsAnonymous};
 use polars_python::error::PyPolarsErr;
 use polars_python::lazyframe::PyLazyFrame;
@@ -33,6 +36,7 @@ use crate::utils::convert_arrow_rb_schema_to_polars_df_schema;
 
 const LEFT_TABLE: &str = "s1";
 const RIGHT_TABLE: &str = "s2";
+const DEFAULT_TABLE_NAME: &str = "unnamed_table";
 const DEFAULT_COLUMN_NAMES: [&str; 3] = ["contig", "start", "end"];
 
 #[pyfunction]
@@ -403,6 +407,48 @@ fn py_from_polars(
     })
 }
 
+#[pyfunction]
+#[pyo3(signature = (py_ctx, path, column))]
+fn base_sequance_quality_scan(
+    py: Python<'_>,
+    py_ctx: &PyBioSessionContext,
+    path: String,
+    column: String,
+) -> PyResult<PyDataFrame> {
+    py.allow_threads(|| {
+        let ctx = &py_ctx.ctx;
+        let rt = Runtime::new().unwrap();
+        maybe_register_table(path, &DEFAULT_TABLE_NAME.to_string(), None, ctx, &rt);
+        let data_frame = rt.block_on(do_base_sequence_quality(
+            ctx,
+            DEFAULT_TABLE_NAME.to_string(),
+            column.to_string(),
+        ));
+        Ok(PyDataFrame::new(data_frame))
+    })
+}
+
+#[pyfunction]
+#[pyo3(signature = (py_ctx, df, column))]
+fn base_sequance_quality_frame(
+    py: Python<'_>,
+    py_ctx: &PyBioSessionContext,
+    df: PyArrowType<ArrowArrayStreamReader>,
+    column: String,
+) -> PyResult<PyDataFrame> {
+    py.allow_threads(|| {
+        let ctx = &py_ctx.ctx;
+        let rt = Runtime::new().unwrap();
+        register_frame(py_ctx, df, DEFAULT_TABLE_NAME.to_string());
+        let data_frame = rt.block_on(do_base_sequence_quality(
+            ctx,
+            DEFAULT_TABLE_NAME.to_string(),
+            column.to_string(),
+        ));
+        Ok(PyDataFrame::new(data_frame))
+    })
+}
+
 #[pymodule]
 fn polars_bio(_py: Python, m: &Bound<PyModule>) -> PyResult<()> {
     pyo3_log::init();
@@ -417,7 +463,8 @@ fn polars_bio(_py: Python, m: &Bound<PyModule>) -> PyResult<()> {
     m.add_function(wrap_pyfunction!(py_describe_vcf, m)?)?;
     m.add_function(wrap_pyfunction!(py_register_view, m)?)?;
     m.add_function(wrap_pyfunction!(py_from_polars, m)?)?;
-    // m.add_function(wrap_pyfunction!(unary_operation_scan, m)?)?;
+    m.add_function(wrap_pyfunction!(base_sequance_quality_frame, m)?)?;
+    m.add_function(wrap_pyfunction!(base_sequance_quality_scan, m)?)?;
     m.add_class::<PyBioSessionContext>()?;
     m.add_class::<FilterOp>()?;
     m.add_class::<RangeOp>()?;
diff --git a/src/operation.rs b/src/operation.rs
index 13ff545f..bd50e182 100644
--- a/src/operation.rs
+++ b/src/operation.rs
@@ -6,8 +6,10 @@ use log::{debug, info};
 use sequila_core::session_context::{Algorithm, SequilaConfig};
 use tokio::runtime::Runtime;
 
+use crate::sequence_quality_histogram::SequenceQualityHistogramProvider;
 use crate::context::set_option_internal;
 use crate::option::{FilterOp, RangeOp, RangeOptions};
+use crate::quantile_stats::QuantileStatsTableProvider;
 use crate::query::{count_overlaps_query, nearest_query, overlap_query};
 use crate::udtf::CountOverlapsProvider;
 use crate::utils::default_cols_to_string;
@@ -191,6 +193,45 @@ async fn do_count_overlaps_coverage_naive(
     ctx.sql(&query).await.unwrap()
 }
 
+pub(crate) async fn do_base_sequence_quality(
+    ctx: &ExonSession,
+    table: String,
+    column: String,
+) -> datafusion::dataframe::DataFrame {
+    let session = Arc::new(ctx.session.clone());
+    let base_provider = Arc::new(SequenceQualityHistogramProvider::new(
+        session.clone(),
+        table.clone(),
+        column,
+    ));
+
+    let base_table_name = format!("{}_decoded", table);
+    session.deregister_table(base_table_name.clone()).unwrap();
+    session
+        .register_table(&base_table_name, base_provider)
+        .unwrap();
+
+    let query = format!(
+        "SELECT pos, score, SUM(count) as count FROM {} GROUP BY pos, score",
+        base_table_name
+    );
+    let base_df = ctx.sql(&query).await.unwrap();
+    let base_plan = base_df.create_physical_plan().await.unwrap();
+
+    let quantile_provider = Arc::new(QuantileStatsTableProvider::new(base_plan));
+
+    let quantile_table_name = format!("{}_quantiles", table);
+    session
+        .deregister_table(quantile_table_name.clone())
+        .unwrap();
+    session
+        .register_table(&quantile_table_name, quantile_provider)
+        .unwrap();
+
+    let query = format!("SELECT * FROM {}", quantile_table_name);
+    ctx.sql(&query).await.unwrap()
+}
+
 async fn get_non_join_columns(
     table_name: String,
     join_columns: Vec<String>,
diff --git a/src/quantile_stats.rs b/src/quantile_stats.rs
new file mode 100644
index 00000000..43645027
--- /dev/null
+++ b/src/quantile_stats.rs
@@ -0,0 +1,268 @@
+use std::any::Any;
+use std::collections::HashMap;
+use std::fmt::{Debug, Formatter};
+use std::sync::Arc;
+
+use arrow::array::{Array, Float64Builder, UInt64Array, UInt64Builder, UInt8Array};
+use arrow::compute::concat_batches;
+use arrow::datatypes::{DataType, Field, Schema, SchemaRef};
+use arrow::record_batch::RecordBatch;
+use async_trait::async_trait;
+use datafusion::catalog::{Session, TableProvider};
+use datafusion::datasource::TableType;
+use datafusion::error::Result;
+use datafusion::execution::context::TaskContext;
+use datafusion::physical_expr::EquivalenceProperties;
+use datafusion::physical_plan::memory::MemoryStream;
+use datafusion::physical_plan::{
+    collect, DisplayAs, DisplayFormatType, ExecutionMode, ExecutionPlan, Partitioning,
+    PlanProperties, SendableRecordBatchStream,
+};
+
+pub struct QuantileStatsTableProvider {
+    input: Arc<dyn ExecutionPlan>,
+    schema: SchemaRef,
+}
+
+impl QuantileStatsTableProvider {
+    pub fn new(input: Arc<dyn ExecutionPlan>) -> Self {
+        let schema = Arc::new(Schema::new(vec![
+            Field::new("pos", DataType::UInt64, false),
+            Field::new("avg", DataType::Float64, true),
+            Field::new("q1", DataType::Float64, true),
+            Field::new("median", DataType::Float64, true),
+            Field::new("q3", DataType::Float64, true),
+            Field::new("lower", DataType::Float64, true),
+            Field::new("upper", DataType::Float64, true),
+        ]));
+        Self {
+            input,
+            schema,
+        }
+    }
+}
+
+impl Debug for QuantileStatsTableProvider {
+    fn fmt(&self, _f: &mut Formatter<'_>) -> std::fmt::Result {
+        Ok(())
+    }
+}
+
+#[async_trait]
+impl TableProvider for QuantileStatsTableProvider {
+    fn as_any(&self) -> &dyn std::any::Any {
+        self
+    }
+
+    fn schema(&self) -> SchemaRef {
+        self.schema.clone()
+    }
+
+    fn table_type(&self) -> TableType {
+        TableType::Base
+    }
+
+    async fn scan(
+        &self,
+        _state: &dyn Session,
+        _projection: Option<&Vec<usize>>,
+        _filters: &[datafusion::logical_expr::Expr],
+        _limit: Option<usize>,
+    ) -> datafusion::error::Result<Arc<dyn ExecutionPlan>> {
+        Ok(Arc::new(QuantileStatsExec::new(self.input.clone())))
+    }
+}
+
+#[derive(Debug)]
+pub struct QuantileStatsExec {
+    input: Arc<dyn ExecutionPlan>,
+    schema: SchemaRef,
+    properties: PlanProperties,
+}
+
+impl QuantileStatsExec {
+    pub fn new(input: Arc<dyn ExecutionPlan>) -> Self {
+        let schema = Arc::new(Schema::new(vec![
+            Field::new("pos", DataType::UInt64, false),
+            Field::new("avg", DataType::Float64, true),
+            Field::new("q1", DataType::Float64, true),
+            Field::new("median", DataType::Float64, true),
+            Field::new("q3", DataType::Float64, true),
+            Field::new("lower", DataType::Float64, true),
+            Field::new("upper", DataType::Float64, true),
+        ]));
+
+        let schema_clone = schema.clone();
+
+        Self {
+            input,
+            schema,
+            properties: PlanProperties::new(
+                EquivalenceProperties::new(schema_clone),
+                Partitioning::UnknownPartitioning(1),
+                ExecutionMode::Bounded,
+            ),
+        }
+    }
+}
+
+impl ExecutionPlan for QuantileStatsExec {
+    fn name(&self) -> &str {
+        "QuantileAggregateExec"
+    }
+
+    fn as_any(&self) -> &dyn Any {
+        self
+    }
+
+    fn schema(&self) -> SchemaRef {
+        Arc::clone(&self.schema)
+    }
+
+    fn properties(&self) -> &PlanProperties {
+        &self.properties
+    }
+
+    fn children(&self) -> Vec<&Arc<dyn ExecutionPlan>> {
+        vec![&self.input]
+    }
+
+    fn with_new_children(
+        self: Arc<Self>,
+        _children: Vec<Arc<dyn ExecutionPlan>>,
+    ) -> Result<Arc<dyn ExecutionPlan>> {
+        Ok(self)
+    }
+
+    fn execute(
+        &self,
+        _partition: usize,
+        context: Arc<TaskContext>,
+    ) -> Result<SendableRecordBatchStream> {
+        let input = self.input.clone();
+        let schema = self.schema.clone();
+
+        let batches = futures::executor::block_on(collect(input, context.clone()))?;
+        let combined = concat_batches(&self.input.schema(), &batches)?;
+        let pos_array = combined
+            .column_by_name("pos")
+            .expect("Column 'pos' not found")
+            .as_any()
+            .downcast_ref::<UInt64Array>()
+            .expect("Expected UInt64 for pos");
+
+        let score_array = combined
+            .column_by_name("score")
+            .expect("Column 'score' not found")
+            .as_any()
+            .downcast_ref::<UInt8Array>()
+            .expect("Expected UInt8 for score");
+
+        let count_array = combined
+            .column_by_name("count")
+            .expect("Column 'count' not found")
+            .as_any()
+            .downcast_ref::<UInt64Array>()
+            .expect("Expected UInt64 for count");
+
+        let mut groups: HashMap<u64, Vec<u64>> = HashMap::new();
+        for i in 0..combined.num_rows() {
+            if pos_array.is_valid(i) && score_array.is_valid(i) && count_array.is_valid(i) {
+                let pos = pos_array.value(i);
+                let score = score_array.value(i);
+                let count = count_array.value(i);
+                let entry = groups.entry(pos).or_insert_with(|| vec![0; 256]);
+                entry[score as usize] += count;
+            }
+        }
+
+        let mut pos_builder = UInt64Builder::with_capacity(groups.len());
+        let mut avg_builder = Float64Builder::with_capacity(groups.len());
+        let mut q1_builder = Float64Builder::with_capacity(groups.len());
+        let mut median_builder = Float64Builder::with_capacity(groups.len());
+        let mut q3_builder = Float64Builder::with_capacity(groups.len());
+        let mut lower_builder = Float64Builder::with_capacity(groups.len());
+        let mut upper_builder = Float64Builder::with_capacity(groups.len());
+
+        for (pos, hist) in groups {
+            if let Some((average, q1, median, q3, lower, upper)) = calculate_histogram_stats(&hist)
+            {
+                pos_builder.append_value(pos);
+                avg_builder.append_value(average);
+                q1_builder.append_value(q1);
+                median_builder.append_value(median);
+                q3_builder.append_value(q3);
+                lower_builder.append_value(lower);
+                upper_builder.append_value(upper);
+            }
+        }
+
+        let result_batch = RecordBatch::try_new(
+            schema.clone(),
+            vec![
+                Arc::new(pos_builder.finish()),
+                Arc::new(avg_builder.finish()),
+                Arc::new(q1_builder.finish()),
+                Arc::new(median_builder.finish()),
+                Arc::new(q3_builder.finish()),
+                Arc::new(lower_builder.finish()),
+                Arc::new(upper_builder.finish()),
+            ],
+        )?;
+        let mem_stream = MemoryStream::try_new(vec![result_batch], schema, None)?;
+        Ok(Box::pin(mem_stream))
+    }
+}
+
+impl DisplayAs for QuantileStatsExec {
+    fn fmt_as(&self, _t: DisplayFormatType, _f: &mut Formatter) -> std::fmt::Result {
+        Ok(())
+    }
+}
+
+fn calculate_histogram_stats(hist: &[u64]) -> Option<(f64, f64, f64, f64, f64, f64)> {
+    let total_count: u64 = hist.iter().sum();
+    if total_count == 0 {
+        return None;
+    }
+
+    let weighted_sum: u64 = hist
+        .iter()
+        .enumerate()
+        .map(|(score, &count)| score as u64 * count)
+        .sum();
+    let average = weighted_sum as f64 / total_count as f64;
+
+    fn quantile(hist: &[u64], quantile: f64, total: u64) -> f64 {
+        let target = quantile * (total - 1) as f64;
+        let target_ = target.floor();
+        let delta = target - target_;
+        let n = target_ as u64 + 1;
+        let mut lo = None;
+        let mut acc = 0u64;
+        for (hi, &count) in hist.iter().enumerate().filter(|(_, &count)| count > 0) {
+            if acc == n && lo.is_some() {
+                let lo = lo.unwrap() as f64;
+                return  (lo + (hi as f64 - lo) * delta) as f64;
+            } else if acc + count > n {
+                return  hi as f64;
+            }
+            acc += count;
+            lo = Some(hi);
+        }
+
+        hist.iter().enumerate().fold(
+            0_usize,
+            |acc, (value, &count)| if count > 0 { value } else { acc },
+        ) as f64
+    }
+
+    let q1 = quantile(hist, 0.25, total_count);
+    let median = quantile(hist, 0.5, total_count);
+    let q3 = quantile(hist, 0.75, total_count);
+    let iqr = q3 - q1;
+    let lower = q1 - 1.5 * iqr;
+    let upper = q3 + 1.5 * iqr;
+
+    Some((average, q1, median, q3, lower, upper))
+}
diff --git a/src/scan.rs b/src/scan.rs
index 4d5b288e..34412780 100644
--- a/src/scan.rs
+++ b/src/scan.rs
@@ -61,6 +61,8 @@ pub(crate) fn get_input_format(path: &str) -> InputFormat {
         InputFormat::Bed
     } else if path.ends_with(".vcf") || path.ends_with(".vcf.gz") || path.ends_with(".vcf.bgz") {
         InputFormat::Vcf
+    } else if path.ends_with(".fastq") {
+        InputFormat::Fastq
     } else {
         panic!("Unsupported format")
     }
diff --git a/src/sequence_quality_histogram.rs b/src/sequence_quality_histogram.rs
new file mode 100644
index 00000000..9ea963ed
--- /dev/null
+++ b/src/sequence_quality_histogram.rs
@@ -0,0 +1,242 @@
+use std::any::Any;
+use std::collections::HashMap;
+use std::fmt::{Debug, Formatter};
+use std::sync::Arc;
+
+use arrow_array::{Array, StringArray};
+use async_trait::async_trait;
+use datafusion::arrow::datatypes::{DataType, Field, Schema, SchemaRef};
+use datafusion::arrow::record_batch::RecordBatch;
+use datafusion::catalog::{Session, TableProvider};
+use datafusion::datasource::TableType;
+use datafusion::error::{DataFusionError, Result};
+use datafusion::execution::context::TaskContext;
+use datafusion::physical_expr::EquivalenceProperties;
+use datafusion::physical_plan::repartition::RepartitionExec;
+use datafusion::physical_plan::stream::RecordBatchStreamAdapter;
+use datafusion::physical_plan::{
+    DisplayAs, DisplayFormatType, ExecutionMode, ExecutionPlan, Partitioning, PlanProperties,
+    SendableRecordBatchStream,
+};
+use datafusion::prelude::{col, SessionContext};
+use futures::stream::BoxStream;
+use futures::TryStreamExt;
+pub struct SequenceQualityHistogramProvider {
+    session: Arc<SessionContext>,
+    table_name: String,
+    column_name: String,
+    schema: SchemaRef,
+}
+
+impl SequenceQualityHistogramProvider {
+    pub fn new(session: Arc<SessionContext>, table_name: String, column_name: String) -> Self {
+        let schema = Arc::new(Schema::new(vec![
+            Field::new("pos", DataType::UInt64, false),
+            Field::new("score", DataType::UInt8, false),
+            Field::new("count", DataType::UInt64, false),
+        ]));
+        Self {
+            session,
+            table_name,
+            column_name,
+            schema,
+        }
+    }
+}
+
+impl Debug for SequenceQualityHistogramProvider {
+    fn fmt(&self, _f: &mut Formatter<'_>) -> std::fmt::Result {
+        Ok(())
+    }
+}
+
+#[async_trait]
+impl TableProvider for SequenceQualityHistogramProvider {
+    fn as_any(&self) -> &dyn std::any::Any {
+        self
+    }
+
+    fn schema(&self) -> SchemaRef {
+        self.schema.clone()
+    }
+
+    fn table_type(&self) -> TableType {
+        todo!()
+    }
+
+    async fn scan(
+        &self,
+        _state: &dyn Session,
+        _projection: Option<&Vec<usize>>,
+        _filters: &[datafusion::prelude::Expr],
+        _limit: Option<usize>,
+    ) -> Result<Arc<dyn ExecutionPlan>> {
+        let target_partitions = self.session.state().config().target_partitions();
+        Ok(Arc::new(SequenceQualityHistogramExec {
+            schema: self.schema.clone(),
+            session: self.session.clone(),
+            table_name: self.table_name.clone(),
+            column_name: self.column_name.clone(),
+            properties: PlanProperties::new(
+                EquivalenceProperties::new(self.schema.clone()),
+                Partitioning::UnknownPartitioning(target_partitions),
+                ExecutionMode::Bounded,
+            ),
+        }))
+    }
+}
+
+pub struct SequenceQualityHistogramExec {
+    schema: SchemaRef,
+    session: Arc<SessionContext>,
+    table_name: String,
+    column_name: String,
+    properties: PlanProperties,
+}
+
+impl Debug for SequenceQualityHistogramExec {
+    fn fmt(&self, _f: &mut Formatter<'_>) -> std::fmt::Result {
+        Ok(())
+    }
+}
+
+impl DisplayAs for SequenceQualityHistogramExec {
+    fn fmt_as(&self, _t: DisplayFormatType, _f: &mut Formatter) -> std::fmt::Result {
+        Ok(())
+    }
+}
+
+impl ExecutionPlan for SequenceQualityHistogramExec {
+    fn name(&self) -> &str {
+        "BaseSequenceQualityExec"
+    }
+
+    fn as_any(&self) -> &dyn Any {
+        self
+    }
+
+    fn schema(&self) -> SchemaRef {
+        self.schema.clone()
+    }
+
+    fn properties(&self) -> &PlanProperties {
+        &self.properties
+    }
+
+    fn children(&self) -> Vec<&Arc<dyn ExecutionPlan>> {
+        vec![]
+    }
+
+    fn with_new_children(
+        self: Arc<Self>,
+        _children: Vec<Arc<dyn ExecutionPlan>>,
+    ) -> Result<Arc<dyn ExecutionPlan>> {
+        Ok(self)
+    }
+
+    fn execute(
+        &self,
+        partition: usize,
+        context: Arc<TaskContext>,
+    ) -> Result<SendableRecordBatchStream> {
+        let fut = get_stream(
+            self.session.clone(),
+            self.table_name.clone(),
+            self.column_name.clone(),
+            self.properties.partitioning.partition_count(),
+            partition,
+            context,
+            self.schema.clone(),
+        );
+        let stream = futures::stream::once(fut).try_flatten();
+        let schema = self.schema.clone();
+        Ok(Box::pin(RecordBatchStreamAdapter::new(schema, stream)))
+    }
+}
+
+fn decode_score(c: char) -> Option<u8> {
+    let ascii = c as u8;
+    if ascii >= 33 {
+        Some(ascii - 33)
+    } else {
+        None
+    }
+}
+
+async fn get_stream(
+    session: Arc<SessionContext>,
+    table_name: String,
+    column_name: String,
+    target_partitions: usize,
+    partition: usize,
+    context: Arc<TaskContext>,
+    new_schema: SchemaRef,
+) -> Result<SendableRecordBatchStream, DataFusionError> {
+    let df = session
+        .table(table_name.clone())
+        .await?
+        .select(vec![col(&column_name)])?;
+
+    let plan = df.create_physical_plan().await?;
+
+    let repartition_stream =
+        RepartitionExec::try_new(plan, Partitioning::RoundRobinBatch(target_partitions))?;
+
+    let partition_stream = repartition_stream.execute(partition, context)?;
+
+    let final_pos_map = partition_stream.try_fold(HashMap::new(), |mut pos_map, batch| async move {
+        let col = batch.column(0); // tylko jedna kolumna
+
+        let col = arrow::compute::cast(col, &DataType::Utf8)
+            .map_err(|e| DataFusionError::Internal(format!("Cast error: {e}")))?;
+
+        let col = col
+            .as_any()
+            .downcast_ref::<StringArray>()
+            .ok_or_else(|| DataFusionError::Internal("Expected StringArray".into()))?;
+
+        col.iter().for_each(|s_opt| {
+            if let Some(s) = s_opt {
+                s.bytes().enumerate().for_each(|(pos, byte)| {
+                    if let Some(score) = decode_score(byte as char) {
+                        let entry = pos_map.entry(pos).or_insert_with(|| vec![0u64; 94]);
+                        if (score as usize) < entry.len() {
+                            entry[score as usize] += 1;
+                        }
+                    }
+                });
+            }
+        });
+
+        Ok(pos_map)
+    }).await?;
+
+    let mut positions = Vec::new();
+    let mut scores = Vec::new();
+    let mut counts = Vec::new();
+
+    for (pos, counts_vec) in final_pos_map {
+        for (score, &count) in counts_vec.iter().enumerate() {
+            if count > 0 {
+                positions.push(pos as u64);
+                scores.push(score as u8);
+                counts.push(count as u64);
+            }
+        }
+    }
+    let pos_array = Arc::new(arrow_array::UInt64Array::from(positions));
+    let score_array = Arc::new(arrow_array::UInt8Array::from(scores));
+    let count_array = Arc::new(arrow_array::UInt64Array::from(counts));
+    let new_batch = RecordBatch::try_new(
+        new_schema.clone(),
+        vec![pos_array, score_array, count_array],
+    )
+    .map_err(|e| DataFusionError::Internal(format!("Error creating RecordBatch: {e}")))?;
+
+    let iter = futures::stream::once(async move { Ok(new_batch) });
+
+    let adapted_stream =
+        RecordBatchStreamAdapter::new(new_schema.clone(), Box::pin(iter) as BoxStream<_>);
+
+    Ok(Box::pin(adapted_stream))
+}
diff --git a/tests/test_base_sequence_quality.py b/tests/test_base_sequence_quality.py
new file mode 100644
index 00000000..f7b278bd
--- /dev/null
+++ b/tests/test_base_sequence_quality.py
@@ -0,0 +1,215 @@
+from pathlib import Path
+import polars as pl
+import pandas as pd
+
+import pytest
+
+import polars_bio as pb
+
+
+class TestBaseSequenceQuality:
+    def record_header(self, len: int):
+        return f"@test\n{'N'*len}\n+\n"
+
+    def simple_test_data(self):
+        data = self.record_header(1) + chr(5 + 33) + "\n"
+        result = pl.DataFrame(
+            {
+                "pos": [0],
+                "avg": [5.0],
+                "q1": [5.0],
+                "median": [5.0],
+                "q3": [5.0],
+                "lower": [5.0],
+                "upper": [5.0],
+            }
+        )
+
+        return data, result
+
+    @pytest.mark.usefixtures("tmp_path")
+    def test_result_from_empty_fastq_should_be_empty_df_polars(self, tmp_path: Path):
+        fastq_file = tmp_path / "test.fastq"
+        fastq_file.write_text("", encoding="ascii")
+
+        result = pb.base_sequence_quality(fastq_file)
+        assert isinstance(result, pl.DataFrame)
+        assert pb.base_sequence_quality(fastq_file).is_empty()
+
+    @pytest.mark.usefixtures("tmp_path")
+    def test_result_from_empty_fastq_should_be_empty_df_pandas(self, tmp_path: Path):
+        fastq_file = tmp_path / "test.fastq"
+        fastq_file.write_text("", encoding="ascii")
+
+        result = pb.base_sequence_quality(fastq_file, output_type="pandas.DataFrame")
+        assert isinstance(result, pd.DataFrame)
+        assert pb.base_sequence_quality(fastq_file).is_empty()
+
+    @pytest.mark.usefixtures("tmp_path")
+    def test_one_record_one_length(self, tmp_path: Path):
+        data, expected_result = self.simple_test_data()
+        fastq_file = tmp_path / "test.fastq"
+        fastq_file.write_text(data, encoding="ascii")
+
+        result = pb.base_sequence_quality(fastq_file)
+        assert result.equals(expected_result)
+
+    @pytest.mark.usefixtures("tmp_path")
+    def test_one_record_one_length_lazyframe(self, tmp_path: Path):
+        data, expected_result = self.simple_test_data()
+        fastq_file = tmp_path / "test.fastq"
+        fastq_file.write_text(data, encoding="ascii")
+
+        lf = pb.read_fastq(str(fastq_file))
+        result = pb.base_sequence_quality(lf)
+
+        assert result.equals(expected_result)
+
+    @pytest.mark.usefixtures("tmp_path")
+    def test_one_record_one_length_polars(self, tmp_path: Path):
+        data, expected_result = self.simple_test_data()
+        fastq_file = tmp_path / "test.fastq"
+        fastq_file.write_text(data, encoding="ascii")
+
+        lf = pb.read_fastq(str(fastq_file))
+        polars_df = lf.collect()
+        result = pb.base_sequence_quality(polars_df)
+
+        assert result.equals(expected_result)
+
+    @pytest.mark.usefixtures("tmp_path")
+    def test_one_record_one_length_pandas(self, tmp_path: Path):
+        data, expected_result = self.simple_test_data()
+        fastq_file = tmp_path / "test.fastq"
+        fastq_file.write_text(data, encoding="ascii")
+
+        lf = pb.read_fastq(str(fastq_file))
+        pandas_df = lf.collect().to_pandas()
+        result = pb.base_sequence_quality(pandas_df)
+
+        assert result.equals(expected_result)
+
+    @pytest.mark.usefixtures("tmp_path")
+    def test_one_record_two_length(self, tmp_path: Path):
+        fastq_file = tmp_path / "test.fastq"
+        fastq_file.write_text(
+            self.record_header(1) + chr(5 + 33) + chr(6 + 33) + "\n",
+            encoding="ascii",
+        )
+
+        result = pb.base_sequence_quality(fastq_file).sort(by="pos")
+        assert result.equals(
+            pl.DataFrame(
+                {
+                    "pos": [0, 1],
+                    "avg": [5.0, 6.0],
+                    "q1": [5.0, 6.0],
+                    "median": [5.0, 6.0],
+                    "q3": [5.0, 6.0],
+                    "lower": [5.0, 6.0],
+                    "upper": [5.0, 6.0],
+                }
+            )
+        )
+
+    @pytest.mark.usefixtures("tmp_path")
+    def test_two_record_one_length(self, tmp_path: Path):
+        fastq_file = tmp_path / "test.fastq"
+
+        file_content = ""
+        for read in [0, 2]:
+            file_content += self.record_header(2) + chr(read + 33) + "\n"
+
+        fastq_file.write_text(file_content, encoding="ascii")
+
+        result = pb.base_sequence_quality(fastq_file)
+        assert result.equals(
+            pl.DataFrame(
+                {
+                    "pos": [0],
+                    "avg": [1.0],
+                    "q1": [0.5],
+                    "median": [1.0],
+                    "q3": [1.5],
+                    "lower": [-1.0],
+                    "upper": [3.0],
+                }
+            )
+        )
+
+    @pytest.mark.usefixtures("tmp_path")
+    def test_three_record_one_length(self, tmp_path: Path):
+        fastq_file = tmp_path / "test.fastq"
+
+        file_content = ""
+        for read in [0, 2, 4]:
+            file_content += self.record_header(3) + chr(read + 33) + "\n"
+
+        fastq_file.write_text(file_content, encoding="ascii")
+
+        result = pb.base_sequence_quality(fastq_file)
+        assert result.equals(
+            pl.DataFrame(
+                {
+                    "pos": [0],
+                    "avg": [2.0],
+                    "q1": [1.0],
+                    "median": [2.0],
+                    "q3": [3.0],
+                    "lower": [-2.0],
+                    "upper": [6.0],
+                }
+            )
+        )
+
+    @pytest.mark.usefixtures("tmp_path")
+    def test_four_record_one_length(self, tmp_path: Path):
+        fastq_file = tmp_path / "test.fastq"
+
+        file_content = ""
+        for read in [0, 2, 4, 9]:
+            file_content += self.record_header(3) + chr(read + 33) + "\n"
+
+        fastq_file.write_text(file_content, encoding="ascii")
+
+        result = pb.base_sequence_quality(fastq_file)
+        assert result.equals(
+            pl.DataFrame(
+                {
+                    "pos": [0],
+                    "avg": [3.75],
+                    "q1": [1.5],
+                    "median": [3.0],
+                    "q3": [5.25],
+                    "lower": [-4.125],
+                    "upper": [10.875],
+                }
+            )
+        )
+
+    @pytest.mark.usefixtures("tmp_path")
+    def test_four_record_two_length(self, tmp_path: Path):
+        fastq_file = tmp_path / "test.fastq"
+
+        file_content = ""
+        for read1, read2 in zip([0, 2, 4, 9], [1, 3, 5, 10]):
+            file_content += (
+                self.record_header(3) + chr(read1 + 33) + chr(read2 + 33) + "\n"
+            )
+
+        fastq_file.write_text(file_content, encoding="ascii")
+
+        result = pb.base_sequence_quality(fastq_file).sort(by="pos")
+        assert result.equals(
+            pl.DataFrame(
+                {
+                    "pos": [0, 1],
+                    "avg": [3.75, 4.75],
+                    "q1": [1.5, 2.5],
+                    "median": [3.0, 4.0],
+                    "q3": [5.25, 6.25],
+                    "lower": [-4.125, -3.125],
+                    "upper": [10.875, 11.875],
+                }
+            )
+        )