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| 1 | +# Allen Institute Nautilex 2026 Challenge Capsules |
| 2 | + |
| 3 | +This repository documents an AI-driven implementation sprint for the **Allen Institute Nautilex 2026** hackathon challenges. |
| 4 | + |
| 5 | +The goal was simple: take the challenge prompts, build a **Code Ocean capsule** for each one, run them as standalone research products, review the results honestly, and iterate fast. |
| 6 | + |
| 7 | +Over **4 days** and **3 implementation / review iterations**, the work was driven through **Code Ocean Aqua** and **Claude Code**: |
| 8 | + |
| 9 | +- **Aqua** was used as the Code Ocean agent layer for building and running the capsules. |
| 10 | +- **Claude Code** was used as the coding agent to implement and revise the capsules. |
| 11 | +- Claude Code was also used as a critic across iterations to review outputs, identify gaps, and drive the next round of fixes. |
| 12 | + |
| 13 | +## Live Atlas |
| 14 | + |
| 15 | +- **GitHub Pages atlas:** https://codeocean.github.io/challenges-capsules/ |
| 16 | +- **Repo atlas source:** [index.html](./index.html) |
| 17 | +- **Repo capsule index:** [index.md](./index.md) |
| 18 | +- **Iteration 03 summary:** [working-capsules-summary.md](./review-challanges-iteration-03/working-capsules-summary.md) |
| 19 | + |
| 20 | +## Outcome |
| 21 | + |
| 22 | +The current repo snapshot covers **15 capsules** for **Challenges 02-16**. |
| 23 | + |
| 24 | +- **10 completed** |
| 25 | +- **4 partially completed** |
| 26 | +- **1 blocked** |
| 27 | + |
| 28 | +The most important outcome is not just the code. It is the combination of: |
| 29 | + |
| 30 | +- runnable capsule implementations |
| 31 | +- capsule-specific READMEs |
| 32 | +- review summaries with honest limitations |
| 33 | +- a local and hosted HTML atlas for fast navigation |
| 34 | + |
| 35 | +## What Is In This Repo |
| 36 | + |
| 37 | +- `challenge_02_*` to `challenge_16_*`: the capsule codebases |
| 38 | +- [`index.html`](./index.html): the main navigable atlas |
| 39 | +- [`docs/`](./docs): styled HTML pages for every local README and review summary |
| 40 | +- [`review-challanges-iteration-03/`](./review-challanges-iteration-03): iteration-03 review bundle |
| 41 | +- [`build-embedded-docs.mjs`](./build-embedded-docs.mjs): rebuilds the embedded markdown bundle |
| 42 | +- [`build-static-doc-pages.mjs`](./build-static-doc-pages.mjs): regenerates the static HTML doc pages |
| 43 | + |
| 44 | +## Quick Navigation |
| 45 | + |
| 46 | +| Challenge | Capsule | Status | Live README | Live Review | |
| 47 | +|---|---|---:|---|---| |
| 48 | +| 02 | Agentic Data Harmonization | Completed | [README](https://codeocean.github.io/challenges-capsules/docs/challenge-02-readme.html) | [Review](https://codeocean.github.io/challenges-capsules/docs/challenge-02-review.html) | |
| 49 | +| 03 | Enhancer Designer | Completed | [README](https://codeocean.github.io/challenges-capsules/docs/challenge-03-readme.html) | [Review](https://codeocean.github.io/challenges-capsules/docs/challenge-03-review.html) | |
| 50 | +| 04 | Light Sheet Alignment QC | Completed | [README](https://codeocean.github.io/challenges-capsules/docs/challenge-04-readme.html) | [Review](https://codeocean.github.io/challenges-capsules/docs/challenge-04-review.html) | |
| 51 | +| 05 | Automate Your Productivity | Partial | [README](https://codeocean.github.io/challenges-capsules/docs/challenge-05-readme.html) | [Review](https://codeocean.github.io/challenges-capsules/docs/challenge-05-review.html) | |
| 52 | +| 06 | Plasmid Forge | Partial | [README](https://codeocean.github.io/challenges-capsules/docs/challenge-06-readme.html) | [Review](https://codeocean.github.io/challenges-capsules/docs/challenge-06-review.html) | |
| 53 | +| 07 | Engineering Automation | Completed | [README](https://codeocean.github.io/challenges-capsules/docs/challenge-07-readme.html) | [Review](https://codeocean.github.io/challenges-capsules/docs/challenge-07-review.html) | |
| 54 | +| 08 | Query BFF | Completed | [README](https://codeocean.github.io/challenges-capsules/docs/challenge-08-readme.html) | [Review](https://codeocean.github.io/challenges-capsules/docs/challenge-08-review.html) | |
| 55 | +| 09 | BindCrafting | Partial | [README](https://codeocean.github.io/challenges-capsules/docs/challenge-09-readme.html) | [Review](https://codeocean.github.io/challenges-capsules/docs/challenge-09-review.html) | |
| 56 | +| 10 | NeuroBase Foundation Model Evaluation | Blocked | [README](https://codeocean.github.io/challenges-capsules/docs/challenge-10-readme.html) | [Review](https://codeocean.github.io/challenges-capsules/docs/challenge-10-review.html) | |
| 57 | +| 11 | ABC Atlas Literature Assistant | Completed | [README](https://codeocean.github.io/challenges-capsules/docs/challenge-11-readme.html) | [Review](https://codeocean.github.io/challenges-capsules/docs/challenge-11-review.html) | |
| 58 | +| 12 | Brain Map + BKP Assistant | Completed | [README](https://codeocean.github.io/challenges-capsules/docs/challenge-12-readme.html) | [Review](https://codeocean.github.io/challenges-capsules/docs/challenge-12-review.html) | |
| 59 | +| 13 | Croissant Pipeline | Completed | [README](https://codeocean.github.io/challenges-capsules/docs/challenge-13-readme.html) | [Review](https://codeocean.github.io/challenges-capsules/docs/challenge-13-review.html) | |
| 60 | +| 14 | Segment Intestine Villi | Completed | [README](https://codeocean.github.io/challenges-capsules/docs/challenge-14-readme.html) | [Review](https://codeocean.github.io/challenges-capsules/docs/challenge-14-review.html) | |
| 61 | +| 15 | Allen Single Cell Model Pantry | Partial | [README](https://codeocean.github.io/challenges-capsules/docs/challenge-15-readme.html) | [Review](https://codeocean.github.io/challenges-capsules/docs/challenge-15-review.html) | |
| 62 | +| 16 | SciDEX | Completed | [README](https://codeocean.github.io/challenges-capsules/docs/challenge-16-readme.html) | [Review](https://codeocean.github.io/challenges-capsules/docs/challenge-16-review.html) | |
| 63 | + |
| 64 | +## Fastest Way To Explore |
| 65 | + |
| 66 | +1. Open the live atlas: https://codeocean.github.io/challenges-capsules/ |
| 67 | +2. Use the sortable top table to scan by challenge, status, inputs, or usage mode. |
| 68 | +3. Open any capsule's HTML README or review page for the styled document view. |
| 69 | +4. Jump into the matching `challenge_*` folder when you want to iterate on the code. |
| 70 | + |
| 71 | +## Quick Iteration Loop |
| 72 | + |
| 73 | +When capsule code or review markdown changes, regenerate the local docs: |
| 74 | + |
| 75 | +```bash |
| 76 | +node build-embedded-docs.mjs |
| 77 | +node build-static-doc-pages.mjs |
| 78 | +``` |
| 79 | + |
| 80 | +Then reopen [`index.html`](./index.html) locally or refresh the GitHub Pages site after pushing. |
| 81 | + |
| 82 | +## Notes |
| 83 | + |
| 84 | +- The current cloned challenge set in this repo starts at **Challenge 02**. |
| 85 | +- The review status labels are intentionally honest: some capsules are strong demonstrations, some are incomplete, and one remains blocked. |
| 86 | +- The atlas and doc pages are static and can be opened directly in a browser over `file://`, with no local server required. |
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