@@ -697,7 +697,7 @@ <h3 data-number="2.6.4" class="anchored" data-anchor-id="running-sctransform"><s
697697< span id ="cb44-3 "> < a href ="#cb44-3 " aria-hidden ="true " tabindex ="-1 "> </ a > end.time < span class ="ot "> <-</ span > < span class ="fu "> Sys.time</ span > ()</ span >
698698< span id ="cb44-4 "> < a href ="#cb44-4 " aria-hidden ="true " tabindex ="-1 "> </ a > end.time < span class ="sc "> -</ span > start.time</ span > </ code > < button title ="Copy to Clipboard " class ="code-copy-button "> < i class ="bi "> </ i > </ button > </ pre > </ div >
699699< div class ="cell-output cell-output-stdout ">
700- < pre > < code > Time difference of 18.36337 secs</ code > </ pre >
700+ < pre > < code > Time difference of 19.10482 secs</ code > </ pre >
701701</ div >
702702</ div >
703703< p > Then run PCA</ p >
@@ -836,7 +836,7 @@ <h3 data-number="2.7.4" class="anchored" data-anchor-id="harmony-integration"><s
836836< span id ="cb49-7 "> < a href ="#cb49-7 " aria-hidden ="true " tabindex ="-1 "> </ a > end.time < span class ="ot "> <-</ span > < span class ="fu "> Sys.time</ span > ()</ span >
837837< span id ="cb49-8 "> < a href ="#cb49-8 " aria-hidden ="true " tabindex ="-1 "> </ a > end.time < span class ="sc "> -</ span > start.time</ span > </ code > < button title ="Copy to Clipboard " class ="code-copy-button "> < i class ="bi "> </ i > </ button > </ pre > </ div >
838838< div class ="cell-output cell-output-stdout ">
839- < pre > < code > Time difference of 10.7184 secs</ code > </ pre >
839+ < pre > < code > Time difference of 11.29752 secs</ code > </ pre >
840840</ div >
841841</ div >
842842< div class ="cell ">
@@ -849,7 +849,7 @@ <h3 data-number="2.7.4" class="anchored" data-anchor-id="harmony-integration"><s
849849< span id ="cb51-7 "> < a href ="#cb51-7 " aria-hidden ="true " tabindex ="-1 "> </ a > end.time < span class ="ot "> <-</ span > < span class ="fu "> Sys.time</ span > ()</ span >
850850< span id ="cb51-8 "> < a href ="#cb51-8 " aria-hidden ="true " tabindex ="-1 "> </ a > end.time < span class ="sc "> -</ span > start.time</ span > </ code > < button title ="Copy to Clipboard " class ="code-copy-button "> < i class ="bi "> </ i > </ button > </ pre > </ div >
851851< div class ="cell-output cell-output-stdout ">
852- < pre > < code > Time difference of 8.304569 secs</ code > </ pre >
852+ < pre > < code > Time difference of 8.645848 secs</ code > </ pre >
853853</ div >
854854</ div >
855855< div class ="cell ">
@@ -866,7 +866,7 @@ <h3 data-number="2.7.4" class="anchored" data-anchor-id="harmony-integration"><s
866866< div class ="sourceCode cell-code " id ="cb55 "> < pre class ="sourceCode r code-with-copy "> < code class ="sourceCode r "> < span id ="cb55-1 "> < a href ="#cb55-1 " aria-hidden ="true " tabindex ="-1 "> </ a > end.time < span class ="ot "> <-</ span > < span class ="fu "> Sys.time</ span > ()</ span >
867867< span id ="cb55-2 "> < a href ="#cb55-2 " aria-hidden ="true " tabindex ="-1 "> </ a > end.time < span class ="sc "> -</ span > start.time</ span > </ code > < button title ="Copy to Clipboard " class ="code-copy-button "> < i class ="bi "> </ i > </ button > </ pre > </ div >
868868< div class ="cell-output cell-output-stdout ">
869- < pre > < code > Time difference of 1.150598 secs</ code > </ pre >
869+ < pre > < code > Time difference of 1.208647 secs</ code > </ pre >
870870</ div >
871871</ div >
872872< div class ="cell ">
@@ -879,7 +879,7 @@ <h3 data-number="2.7.4" class="anchored" data-anchor-id="harmony-integration"><s
879879< span id ="cb57-7 "> < a href ="#cb57-7 " aria-hidden ="true " tabindex ="-1 "> </ a > end.time < span class ="ot "> <-</ span > < span class ="fu "> Sys.time</ span > ()</ span >
880880< span id ="cb57-8 "> < a href ="#cb57-8 " aria-hidden ="true " tabindex ="-1 "> </ a > end.time < span class ="sc "> -</ span > start.time</ span > </ code > < button title ="Copy to Clipboard " class ="code-copy-button "> < i class ="bi "> </ i > </ button > </ pre > </ div >
881881< div class ="cell-output cell-output-stdout ">
882- < pre > < code > Time difference of 10.10729 secs</ code > </ pre >
882+ < pre > < code > Time difference of 10.72018 secs</ code > </ pre >
883883</ div >
884884</ div >
885885</ section >
@@ -985,16 +985,16 @@ <h2 data-number="2.8" class="anchored" data-anchor-id="clustering"><span class="
985985This message will be shown once per session</ code > </ pre >
986986</ div >
987987< div class ="cell-output cell-output-stderr ">
988- < pre > < code > 08:50:07 UMAP embedding parameters a = 0.9922 b = 1.112</ code > </ pre >
988+ < pre > < code > 13:30:15 UMAP embedding parameters a = 0.9922 b = 1.112</ code > </ pre >
989989</ div >
990990< div class ="cell-output cell-output-stderr ">
991- < pre > < code > 08:50:07 Read 1456 rows and found 10 numeric columns</ code > </ pre >
991+ < pre > < code > 13:30:15 Read 1456 rows and found 10 numeric columns</ code > </ pre >
992992</ div >
993993< div class ="cell-output cell-output-stderr ">
994- < pre > < code > 08:50:07 Using Annoy for neighbor search, n_neighbors = 30</ code > </ pre >
994+ < pre > < code > 13:30:15 Using Annoy for neighbor search, n_neighbors = 30</ code > </ pre >
995995</ div >
996996< div class ="cell-output cell-output-stderr ">
997- < pre > < code > 08:50:07 Building Annoy index with metric = cosine, n_trees = 50</ code > </ pre >
997+ < pre > < code > 13:30:15 Building Annoy index with metric = cosine, n_trees = 50</ code > </ pre >
998998</ div >
999999< div class ="cell-output cell-output-stderr ">
10001000< pre > < code > 0% 10 20 30 40 50 60 70 80 90 100%</ code > </ pre >
@@ -1004,86 +1004,86 @@ <h2 data-number="2.8" class="anchored" data-anchor-id="clustering"><span class="
10041004</ div >
10051005< div class ="cell-output cell-output-stderr ">
10061006< pre > < code > **************************************************|
1007- 08:50:08 Writing NN index file to temp file /tmp/Rtmp3GlxL6/file2f29163dab174d
1008- 08:50:08 Searching Annoy index using 1 thread, search_k = 3000
1009- 08:50:08 Annoy recall = 100%
1010- 08:50:09 Commencing smooth kNN distance calibration using 1 thread with target n_neighbors = 30
1011- 08:50:10 Initializing from normalized Laplacian + noise (using RSpectra)
1012- 08:50:10 Commencing optimization for 500 epochs, with 55744 positive edges
1013- 08:50:10 Using rng type: pcg
1014- 08:50:13 Optimization finished</ code > </ pre >
1007+ 13:30:15 Writing NN index file to temp file /tmp/RtmpXqTft1/file1e66443af80802
1008+ 13:30:15 Searching Annoy index using 1 thread, search_k = 3000
1009+ 13:30:16 Annoy recall = 100%
1010+ 13:30:17 Commencing smooth kNN distance calibration using 1 thread with target n_neighbors = 30
1011+ 13:30:18 Initializing from normalized Laplacian + noise (using RSpectra)
1012+ 13:30:18 Commencing optimization for 500 epochs, with 55744 positive edges
1013+ 13:30:18 Using rng type: pcg
1014+ 13:30:21 Optimization finished</ code > </ pre >
10151015</ div >
10161016< div class ="sourceCode cell-code " id ="cb89 "> < pre class ="sourceCode r code-with-copy "> < code class ="sourceCode r "> < span id ="cb89-1 "> < a href ="#cb89-1 " aria-hidden ="true " tabindex ="-1 "> </ a > all_data_sub < span class ="ot "> <-</ span > < span class ="fu "> RunUMAP</ span > (all_data_sub, < span class ="at "> reduction =</ span > < span class ="st "> "integrated.cca"</ span > , < span class ="at "> dims =</ span > < span class ="dv "> 1</ span > < span class ="sc "> :</ span > < span class ="dv "> 10</ span > , < span class ="at "> reduction.name =</ span > < span class ="st "> "umap.cca"</ span > )</ span > </ code > < button title ="Copy to Clipboard " class ="code-copy-button "> < i class ="bi "> </ i > </ button > </ pre > </ div >
10171017< div class ="cell-output cell-output-stderr ">
1018- < pre > < code > 08:50:13 UMAP embedding parameters a = 0.9922 b = 1.112
1019- 08:50:13 Read 1456 rows and found 10 numeric columns
1020- 08:50:13 Using Annoy for neighbor search, n_neighbors = 30
1021- 08:50:13 Building Annoy index with metric = cosine, n_trees = 50
1018+ < pre > < code > 13:30:21 UMAP embedding parameters a = 0.9922 b = 1.112
1019+ 13:30:21 Read 1456 rows and found 10 numeric columns
1020+ 13:30:21 Using Annoy for neighbor search, n_neighbors = 30
1021+ 13:30:21 Building Annoy index with metric = cosine, n_trees = 50
102210220% 10 20 30 40 50 60 70 80 90 100%
10231023[----|----|----|----|----|----|----|----|----|----|
10241024**************************************************|
1025- 08:50:13 Writing NN index file to temp file /tmp/Rtmp3GlxL6/file2f291636acb517
1026- 08:50:13 Searching Annoy index using 1 thread, search_k = 3000
1027- 08:50:13 Annoy recall = 100%
1028- 08:50:14 Commencing smooth kNN distance calibration using 1 thread with target n_neighbors = 30
1029- 08:50:16 Initializing from normalized Laplacian + noise (using RSpectra)
1030- 08:50:16 Commencing optimization for 500 epochs, with 58396 positive edges
1031- 08:50:16 Using rng type: pcg
1032- 08:50:18 Optimization finished</ code > </ pre >
1025+ 13:30:21 Writing NN index file to temp file /tmp/RtmpXqTft1/file1e66445b9bacb2
1026+ 13:30:21 Searching Annoy index using 1 thread, search_k = 3000
1027+ 13:30:21 Annoy recall = 100%
1028+ 13:30:22 Commencing smooth kNN distance calibration using 1 thread with target n_neighbors = 30
1029+ 13:30:24 Initializing from normalized Laplacian + noise (using RSpectra)
1030+ 13:30:24 Commencing optimization for 500 epochs, with 58396 positive edges
1031+ 13:30:24 Using rng type: pcg
1032+ 13:30:26 Optimization finished</ code > </ pre >
10331033</ div >
10341034< div class ="sourceCode cell-code " id ="cb91 "> < pre class ="sourceCode r code-with-copy "> < code class ="sourceCode r "> < span id ="cb91-1 "> < a href ="#cb91-1 " aria-hidden ="true " tabindex ="-1 "> </ a > all_data_sub < span class ="ot "> <-</ span > < span class ="fu "> RunUMAP</ span > (all_data_sub, < span class ="at "> reduction =</ span > < span class ="st "> "integrated.jpca"</ span > , < span class ="at "> dims =</ span > < span class ="dv "> 1</ span > < span class ="sc "> :</ span > < span class ="dv "> 10</ span > , < span class ="at "> reduction.name =</ span > < span class ="st "> "umap.jpca"</ span > )</ span > </ code > < button title ="Copy to Clipboard " class ="code-copy-button "> < i class ="bi "> </ i > </ button > </ pre > </ div >
10351035< div class ="cell-output cell-output-stderr ">
1036- < pre > < code > 08:50:18 UMAP embedding parameters a = 0.9922 b = 1.112
1037- 08:50:18 Read 1456 rows and found 10 numeric columns
1038- 08:50:18 Using Annoy for neighbor search, n_neighbors = 30
1039- 08:50:18 Building Annoy index with metric = cosine, n_trees = 50
1036+ < pre > < code > 13:30:26 UMAP embedding parameters a = 0.9922 b = 1.112
1037+ 13:30:26 Read 1456 rows and found 10 numeric columns
1038+ 13:30:26 Using Annoy for neighbor search, n_neighbors = 30
1039+ 13:30:26 Building Annoy index with metric = cosine, n_trees = 50
104010400% 10 20 30 40 50 60 70 80 90 100%
10411041[----|----|----|----|----|----|----|----|----|----|
10421042**************************************************|
1043- 08:50:18 Writing NN index file to temp file /tmp/Rtmp3GlxL6/file2f29161a5c0631
1044- 08:50:18 Searching Annoy index using 1 thread, search_k = 3000
1045- 08:50:18 Annoy recall = 100%
1046- 08:50:19 Commencing smooth kNN distance calibration using 1 thread with target n_neighbors = 30
1047- 08:50:21 Initializing from normalized Laplacian + noise (using RSpectra)
1048- 08:50:21 Commencing optimization for 500 epochs, with 58918 positive edges
1049- 08:50:21 Using rng type: pcg
1050- 08:50:23 Optimization finished</ code > </ pre >
1043+ 13:30:27 Writing NN index file to temp file /tmp/RtmpXqTft1/file1e66442972fd80
1044+ 13:30:27 Searching Annoy index using 1 thread, search_k = 3000
1045+ 13:30:27 Annoy recall = 100%
1046+ 13:30:28 Commencing smooth kNN distance calibration using 1 thread with target n_neighbors = 30
1047+ 13:30:30 Initializing from normalized Laplacian + noise (using RSpectra)
1048+ 13:30:30 Commencing optimization for 500 epochs, with 58918 positive edges
1049+ 13:30:30 Using rng type: pcg
1050+ 13:30:32 Optimization finished</ code > </ pre >
10511051</ div >
10521052< div class ="sourceCode cell-code " id ="cb93 "> < pre class ="sourceCode r code-with-copy "> < code class ="sourceCode r "> < span id ="cb93-1 "> < a href ="#cb93-1 " aria-hidden ="true " tabindex ="-1 "> </ a > all_data_sub < span class ="ot "> <-</ span > < span class ="fu "> RunUMAP</ span > (all_data_sub, < span class ="at "> reduction =</ span > < span class ="st "> "harmony"</ span > , < span class ="at "> dims =</ span > < span class ="dv "> 1</ span > < span class ="sc "> :</ span > < span class ="dv "> 10</ span > , < span class ="at "> reduction.name =</ span > < span class ="st "> "umap.harmony"</ span > )</ span > </ code > < button title ="Copy to Clipboard " class ="code-copy-button "> < i class ="bi "> </ i > </ button > </ pre > </ div >
10531053< div class ="cell-output cell-output-stderr ">
1054- < pre > < code > 08:50:23 UMAP embedding parameters a = 0.9922 b = 1.112
1055- 08:50:23 Read 1456 rows and found 10 numeric columns
1056- 08:50:23 Using Annoy for neighbor search, n_neighbors = 30
1057- 08:50:23 Building Annoy index with metric = cosine, n_trees = 50
1054+ < pre > < code > 13:30:32 UMAP embedding parameters a = 0.9922 b = 1.112
1055+ 13:30:32 Read 1456 rows and found 10 numeric columns
1056+ 13:30:32 Using Annoy for neighbor search, n_neighbors = 30
1057+ 13:30:32 Building Annoy index with metric = cosine, n_trees = 50
105810580% 10 20 30 40 50 60 70 80 90 100%
10591059[----|----|----|----|----|----|----|----|----|----|
10601060**************************************************|
1061- 08:50:23 Writing NN index file to temp file /tmp/Rtmp3GlxL6/file2f29163f7a3d75
1062- 08:50:23 Searching Annoy index using 1 thread, search_k = 3000
1063- 08:50:24 Annoy recall = 100%
1064- 08:50:24 Commencing smooth kNN distance calibration using 1 thread with target n_neighbors = 30
1065- 08:50:26 Initializing from normalized Laplacian + noise (using RSpectra)
1066- 08:50:26 Commencing optimization for 500 epochs, with 57540 positive edges
1067- 08:50:26 Using rng type: pcg
1068- 08:50:28 Optimization finished</ code > </ pre >
1061+ 13:30:32 Writing NN index file to temp file /tmp/RtmpXqTft1/file1e66441abc6662
1062+ 13:30:32 Searching Annoy index using 1 thread, search_k = 3000
1063+ 13:30:33 Annoy recall = 100%
1064+ 13:30:33 Commencing smooth kNN distance calibration using 1 thread with target n_neighbors = 30
1065+ 13:30:35 Initializing from normalized Laplacian + noise (using RSpectra)
1066+ 13:30:35 Commencing optimization for 500 epochs, with 57540 positive edges
1067+ 13:30:35 Using rng type: pcg
1068+ 13:30:37 Optimization finished</ code > </ pre >
10691069</ div >
10701070< div class ="sourceCode cell-code " id ="cb95 "> < pre class ="sourceCode r code-with-copy "> < code class ="sourceCode r "> < span id ="cb95-1 "> < a href ="#cb95-1 " aria-hidden ="true " tabindex ="-1 "> </ a > all_data_sub < span class ="ot "> <-</ span > < span class ="fu "> RunUMAP</ span > (all_data_sub, < span class ="at "> reduction =</ span > < span class ="st "> "integrated.rpca"</ span > , < span class ="at "> dims =</ span > < span class ="dv "> 1</ span > < span class ="sc "> :</ span > < span class ="dv "> 10</ span > , < span class ="at "> reduction.name =</ span > < span class ="st "> "umap.rpca"</ span > )</ span > </ code > < button title ="Copy to Clipboard " class ="code-copy-button "> < i class ="bi "> </ i > </ button > </ pre > </ div >
10711071< div class ="cell-output cell-output-stderr ">
1072- < pre > < code > 08:50:28 UMAP embedding parameters a = 0.9922 b = 1.112
1073- 08:50:28 Read 1456 rows and found 10 numeric columns
1074- 08:50:28 Using Annoy for neighbor search, n_neighbors = 30
1075- 08:50:28 Building Annoy index with metric = cosine, n_trees = 50
1072+ < pre > < code > 13:30:38 UMAP embedding parameters a = 0.9922 b = 1.112
1073+ 13:30:38 Read 1456 rows and found 10 numeric columns
1074+ 13:30:38 Using Annoy for neighbor search, n_neighbors = 30
1075+ 13:30:38 Building Annoy index with metric = cosine, n_trees = 50
107610760% 10 20 30 40 50 60 70 80 90 100%
10771077[----|----|----|----|----|----|----|----|----|----|
10781078**************************************************|
1079- 08:50:28 Writing NN index file to temp file /tmp/Rtmp3GlxL6/file2f2916195a7045
1080- 08:50:28 Searching Annoy index using 1 thread, search_k = 3000
1081- 08:50:29 Annoy recall = 100%
1082- 08:50:30 Commencing smooth kNN distance calibration using 1 thread with target n_neighbors = 30
1083- 08:50:31 Initializing from normalized Laplacian + noise (using RSpectra)
1084- 08:50:31 Commencing optimization for 500 epochs, with 57330 positive edges
1085- 08:50:31 Using rng type: pcg
1086- 08:50:33 Optimization finished</ code > </ pre >
1079+ 13:30:38 Writing NN index file to temp file /tmp/RtmpXqTft1/file1e664421291c83
1080+ 13:30:38 Searching Annoy index using 1 thread, search_k = 3000
1081+ 13:30:38 Annoy recall = 100%
1082+ 13:30:39 Commencing smooth kNN distance calibration using 1 thread with target n_neighbors = 30
1083+ 13:30:41 Initializing from normalized Laplacian + noise (using RSpectra)
1084+ 13:30:41 Commencing optimization for 500 epochs, with 57330 positive edges
1085+ 13:30:41 Using rng type: pcg
1086+ 13:30:43 Optimization finished</ code > </ pre >
10871087</ div >
10881088</ div >
10891089< div class ="cell ">
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