diff --git a/doc/src/usage/cli.md b/doc/src/usage/cli.md
index e1fdcd0a..25d51744 100644
--- a/doc/src/usage/cli.md
+++ b/doc/src/usage/cli.md
@@ -4,6 +4,35 @@ This page covers a few handy `fuzzamoto-cli` workflows. The CLI is built from th
 `fuzzamoto-cli` crate in this repository and provides utilities for working with
 IR corpora, scenarios, and coverage reports.
 
+## Initialize a campaign with a seed mempool
+
+The `init` subcommand accepts an optional `--seedfile` flag. When provided, the
+raw bytes of the seed file are used to create a `mempool.dat` file, which is then 
+imported via the `importmempool` RPC **before** the snapshot is taken. This means
+every fuzz input will start from a node that already has those transactions in its
+mempool, giving the fuzzer richer starting state.
+
+### Using `--seedfile` with `fuzzamoto-cli init`
+
+Pass the path to the seed file with `--seedfile`:
+
+```bash
+fuzzamoto-cli init \
+  --sharedir /tmp/fuzzamoto_share \
+  --crash-handler /path/to/crash_handler.so \
+  --bitcoind /path/to/bitcoind \
+  --scenario /path/to/scenario-generic \
+  --nyx-dir /path/to/nyx \
+  --seedfile /tmp/my_seed.dat
+```
+
+The generated `fuzz_no_pt.sh` script will automatically download the seed file
+into the Nyx VM and pass it to the scenario binary via `--seedfile`. During
+scenario initialization the seed file's bytes are written as `mempool.dat` and
+imported into the node, then the snapshot is taken with that mempool state so
+every test case executes against a node that starts with pre-populated
+transactions.
+
 ## Generate `ir.context`
 
 The CLI’s `--context` flag expects a context file dumped by the IR scenario. You can produce one outside Nyx as follows:
diff --git a/fuzzamoto-cli/src/commands/init.rs b/fuzzamoto-cli/src/commands/init.rs
index b3e5cd58..31f5835c 100644
--- a/fuzzamoto-cli/src/commands/init.rs
+++ b/fuzzamoto-cli/src/commands/init.rs
@@ -2,6 +2,12 @@ use crate::error::{CliError, Result};
 use crate::utils::{file_ops, nyx, process};
 use std::path::{Path, PathBuf};
 
+pub struct InitOptions<'a> {
+    pub secondary_bitcoind: Option<&'a PathBuf>,
+    pub rpc_path: Option<&'a PathBuf>,
+    pub seedfile: Option<&'a PathBuf>,
+}
+
 pub struct InitCommand;
 
 impl InitCommand {
@@ -9,11 +15,13 @@ impl InitCommand {
         sharedir: &Path,
         crash_handler: &Path,
         bitcoind: &Path,
-        secondary_bitcoind: Option<&PathBuf>,
         scenario: &Path,
         nyx_dir: &Path,
-        rpc_path: Option<&PathBuf>,
+        opts: &InitOptions<'_>,
     ) -> Result<()> {
+        let secondary_bitcoind = opts.secondary_bitcoind;
+        let rpc_path = opts.rpc_path;
+        let seedfile = opts.seedfile;
         file_ops::ensure_sharedir_not_exists(sharedir)?;
         file_ops::create_dir_all(sharedir)?;
 
@@ -30,6 +38,11 @@ impl InitCommand {
             file_ops::copy_file_to_dir(rpc, sharedir)?;
         }
 
+        if let Some(seed) = seedfile {
+            file_ops::ensure_file_exists(seed)?;
+            file_ops::copy_file_to_dir(seed, sharedir)?;
+        }
+
         let mut all_deps = Vec::new();
         let mut binary_names = Vec::new();
 
@@ -117,14 +130,22 @@ impl InitCommand {
             .and_then(|p| p.file_name())
             .and_then(|name| name.to_str());
 
+        let seedfile_name = seedfile
+            .as_ref()
+            .and_then(|p| p.file_name())
+            .and_then(|name| name.to_str());
+
         nyx::create_nyx_script(
             sharedir,
             &all_deps,
             &binary_names,
             &crash_handler_name,
             scenario_name,
-            secondary_name,
-            rpc_name,
+            &nyx::NyxScriptOptions {
+                secondary_bitcoind: secondary_name,
+                rpc_path: rpc_name,
+                seedfile: seedfile_name,
+            },
         )?;
 
         Ok(())
diff --git a/fuzzamoto-cli/src/main.rs b/fuzzamoto-cli/src/main.rs
index cd11ed81..6074956c 100644
--- a/fuzzamoto-cli/src/main.rs
+++ b/fuzzamoto-cli/src/main.rs
@@ -3,6 +3,7 @@ mod error;
 mod utils;
 
 use clap::{Parser, Subcommand};
+use commands::init::InitOptions;
 use commands::{CoverageCommand, InitCommand, IrCommand, ir};
 use error::Result;
 use std::path::PathBuf;
@@ -51,6 +52,12 @@ enum Commands {
             help = "Path to the file with the RPC commands that should be copied into the share directory"
         )]
         rpc_path: Option<PathBuf>,
+
+        #[arg(
+            long,
+            help = "Path to a mempool.dat seed file to be imported into the node's mempool before the snapshot is taken"
+        )]
+        seedfile: Option<PathBuf>,
     },
 
     /// Create a html coverage report for a given corpus
@@ -133,14 +140,18 @@ fn main() -> Result<()> {
             scenario,
             nyx_dir,
             rpc_path,
+            seedfile,
         } => InitCommand::execute(
             sharedir,
             crash_handler,
             bitcoind,
-            secondary_bitcoind.as_ref(),
             scenario,
             nyx_dir,
-            rpc_path.as_ref(),
+            &InitOptions {
+                secondary_bitcoind: secondary_bitcoind.as_ref(),
+                rpc_path: rpc_path.as_ref(),
+                seedfile: seedfile.as_ref(),
+            },
         ),
         Commands::Coverage {
             output,
diff --git a/fuzzamoto-cli/src/utils/nyx.rs b/fuzzamoto-cli/src/utils/nyx.rs
index f08ad721..f38559f5 100644
--- a/fuzzamoto-cli/src/utils/nyx.rs
+++ b/fuzzamoto-cli/src/utils/nyx.rs
@@ -43,15 +43,23 @@ pub fn generate_nyx_config(nyx_path: &Path, sharedir: &Path) -> Result<()> {
     Ok(())
 }
 
+pub struct NyxScriptOptions<'a> {
+    pub secondary_bitcoind: Option<&'a str>,
+    pub rpc_path: Option<&'a str>,
+    pub seedfile: Option<&'a str>,
+}
+
 pub fn create_nyx_script(
     sharedir: &Path,
     all_deps: &[String],
     binary_names: &[String],
     crash_handler_name: &str,
     scenario_name: &str,
-    secondary_bitcoind: Option<&str>,
-    rpc_path: Option<&str>,
+    opts: &NyxScriptOptions<'_>,
 ) -> Result<()> {
+    let secondary_bitcoind = opts.secondary_bitcoind;
+    let rpc_path = opts.rpc_path;
+    let seedfile = opts.seedfile;
     let mut script = vec![
         "chmod +x hget".to_string(),
         "cp hget /tmp".to_string(),
@@ -71,6 +79,10 @@ pub fn create_nyx_script(
         script.push(format!("./hget {rpc_path} {rpc_path}"));
     }
 
+    if let Some(seedfile) = seedfile {
+        script.push(format!("./hget {seedfile} {seedfile}"));
+    }
+
     // Make executables
     for exe in &["habort", "hcat", "ld-linux-x86-64.so.2", crash_handler_name] {
         script.push(format!("chmod +x {exe}"));
@@ -109,12 +121,18 @@ pub fn create_nyx_script(
     script.push(format!("echo \"{proxy_script}\" >> ./bitcoind_proxy"));
     script.push("chmod +x ./bitcoind_proxy".to_string());
 
+    // Build the seedfile argument for the scenario command
+    let seedfile_arg = seedfile
+        .map(|s| format!(" --seedfile {s}"))
+        .unwrap_or_default();
+
     // Run the scenario
     script.push(format!(
-        "RUST_LOG=debug LD_LIBRARY_PATH=/tmp LD_BIND_NOW=1 ./{} ./bitcoind_proxy {} ./{} > log.txt 2>&1",
+        "RUST_LOG=debug LD_LIBRARY_PATH=/tmp LD_BIND_NOW=1 ./{} ./bitcoind_proxy {} ./{}{} > log.txt 2>&1",
         scenario_name,
         rpc_path.unwrap_or(""),
-        secondary_bitcoind.unwrap_or("")
+        secondary_bitcoind.unwrap_or(""),
+        seedfile_arg
     ));
 
     // Debug info
diff --git a/fuzzamoto/src/scenarios/generic.rs b/fuzzamoto/src/scenarios/generic.rs
index 94a86ef7..0cd8f953 100644
--- a/fuzzamoto/src/scenarios/generic.rs
+++ b/fuzzamoto/src/scenarios/generic.rs
@@ -72,7 +72,7 @@ pub struct GenericScenario<TX: Transport, T: Target<TX>> {
 const INTERVAL: u64 = 1;
 
 impl<TX: Transport, T: Target<TX>> GenericScenario<TX, T> {
-    fn from_target(mut target: T) -> Result<Self, String> {
+    fn from_target_with_seedfile(mut target: T, seedfile: Option<&str>) -> Result<Self, String> {
         let genesis_block = bitcoin::blockdata::constants::genesis_block(bitcoin::Network::Regtest);
 
         let mut time = u64::from(genesis_block.header.time);
@@ -209,6 +209,22 @@ impl<TX: Transport, T: Target<TX>> GenericScenario<TX, T> {
             connection.send_and_recv(&("inv".to_string(), encode::serialize(&inv)), false)?;
         }
 
+        // Import mempool from seed file if provided. The seed file's raw bytes are written as
+        // mempool.dat and imported into the node before the snapshot is taken, so fuzz inputs
+        // can interact with pre-existing transactions.
+        if let Some(path) = seedfile {
+            match std::fs::read(path) {
+                Ok(bytes) => {
+                    if let Err(e) = target.import_mempool(&bytes) {
+                        log::warn!("Failed to import mempool from seed file '{path}': {e}");
+                    } else {
+                        log::info!("Imported mempool from seed file: {path}");
+                    }
+                }
+                Err(e) => log::warn!("Failed to read seed file '{path}': {e}"),
+            }
+        }
+
         Ok(Self {
             target,
             time,
@@ -222,7 +238,11 @@ impl<TX: Transport, T: Target<TX>> GenericScenario<TX, T> {
 impl<TX: Transport, T: Target<TX>> Scenario<'_, TestCase> for GenericScenario<TX, T> {
     fn new(args: &[String]) -> Result<Self, String> {
         let target = T::from_path(&args[1])?;
-        Self::from_target(target)
+        let seedfile = args
+            .windows(2)
+            .find(|w| w[0] == "--seedfile")
+            .map(|w| w[1].clone());
+        Self::from_target_with_seedfile(target, seedfile.as_deref())
     }
 
     fn run(&mut self, testcase: TestCase) -> ScenarioResult {
diff --git a/fuzzamoto/src/targets/bitcoin_core.rs b/fuzzamoto/src/targets/bitcoin_core.rs
index e46e9d14..28108fca 100644
--- a/fuzzamoto/src/targets/bitcoin_core.rs
+++ b/fuzzamoto/src/targets/bitcoin_core.rs
@@ -94,6 +94,23 @@ impl TargetNode for BitcoinCoreTarget {
         })
     }
 
+    fn import_mempool(&self, bytes: &[u8]) -> Result<(), String> {
+        let mempool_path = self.node.workdir().join("mempool.dat");
+        std::fs::write(&mempool_path, bytes)
+            .map_err(|e| format!("Failed to write mempool.dat: {e}"))?;
+        self.node
+            .client
+            .call::<serde_json::Value>(
+                "importmempool",
+                &[mempool_path
+                    .to_str()
+                    .ok_or("mempool.dat path is not valid UTF-8")?
+                    .into()],
+            )
+            .map(|_| ())
+            .map_err(|e| format!("Failed to import mempool: {e:?}"))
+    }
+
     fn set_mocktime(&mut self, time: u64) -> Result<(), String> {
         let client = &self.node.client;
 
diff --git a/fuzzamoto/src/targets/mod.rs b/fuzzamoto/src/targets/mod.rs
index f227b43b..b1f5c8cb 100644
--- a/fuzzamoto/src/targets/mod.rs
+++ b/fuzzamoto/src/targets/mod.rs
@@ -24,6 +24,19 @@ pub trait TargetNode: Sized {
 
     /// Check if the target is still alive.
     fn is_alive(&self) -> Result<(), String>;
+
+    /// Create a `mempool.dat` file from the given raw bytes and import it into the node's mempool.
+    ///
+    /// The implementation writes `bytes` to a `mempool.dat` file in the node's working directory
+    /// and then calls `importmempool` on that file. The default implementation is a no-op for
+    /// targets that do not support this operation.
+    ///
+    /// # Arguments
+    ///
+    /// * `bytes` - Raw bytes to write as the `mempool.dat` file content.
+    fn import_mempool(&self, _bytes: &[u8]) -> Result<(), String> {
+        Ok(())
+    }
 }
 
 /// `Target` is the interface that the test harness will use to interact with the target Bitcoin