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lines changed Original file line number Diff line number Diff line change @@ -89,7 +89,7 @@ enabled additional filtering on related metrics:
8989 ` --percentile-threshold ` set, this parameter will influence how both the
9090 binding cutoff and the percentile cutoff are applied. The default,
9191 ` conservative ` , will require a candidate to pass both the binding and the
92- percentile threshold while the ` exploratory ` option will require a candiate
92+ percentile threshold while the ` exploratory ` option will require a candidate
9393 to only pass either the binding or the percentile threshold.
9494
9595### Coverage Filter
Original file line number Diff line number Diff line change @@ -92,7 +92,7 @@ highlighted with a green border.
9292
9393Next, this table lists the IC50 peptide MHC binding affinity for both the Best Peptide
9494(MT) and the matched wild type (WT). These values are either a median of all of the
95- binding predictions made by the predictiors selected in your pVACseq run, or
95+ binding predictions made by the predictors selected in your pVACseq run, or
9696the lowest binding prediction made. This depends on the value set for the
9797` --top-score-metric ` in your run. The table also shows the median/lowest percentile
9898scores of all predictors that provide this value, again depending on the
@@ -279,7 +279,7 @@ ottrpal::include_slide("https://docs.google.com/presentation/d/1uz39zaObDGKhEVCG
279279## Regenerate Tiers with Custom Parameters
280280
281281During review of your data it might become apparent that different tiering
282- thresholds would've been more approriate . pVACview allows you to re-tier your
282+ thresholds would've been more appropriate . pVACview allows you to re-tier your
283283data with custom parameters by adjusting the sliders and inputs in the
284284"Advanced Options: Regenerate Tiering with different parameters" panel and
285285pressing the "Recalculate Tiering with new parameters" button. The tiering
Original file line number Diff line number Diff line change @@ -15,7 +15,7 @@ This chapter will summarize:
1515## Key conclusions
1616
1717In this course you will have gained a better understanding of the current best
18- practices for neoantigen indentification and prioritization. You will have
18+ practices for neoantigen identification and prioritization. You will have
1919learned how to run pVACtools, interpret pVACtools results, and select neoantigen
2020candidates suitable for vaccine manufacturing using pVACview.
2121
Original file line number Diff line number Diff line change @@ -9,6 +9,7 @@ Bloomberg
99Bookdown
1010bioinformatics
1111biotype
12+ CDS
1213CHROM
1314CLI
1415ClinVar
@@ -37,6 +38,7 @@ favicon
3738frameshift
3839fyi
3940GDSCN
41+ GTF
4042GenBank
4143GH
4244GitHub
6668indels
6769inframe
6870itcrtraining
71+ JunctionReadCount
6972json
7073junctional
7174Leanpub
@@ -103,17 +106,20 @@ proteomics
103106pVAC
104107pVACfuse
105108pVACseq
109+ pVACsplice
106110pvactools
107111pVACtools
108112pVACvector
109113pVACview
110114pVACviz
111115RefSeq
116+ RegTools
112117reproducibility
113118somatically
114119subclonal
115120summarization
116121STARFusion
122+ SpanningFragCount
117123tbi
118124tiering
119125TSL
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