diff --git a/.github/workflows/check-bioc.yml b/.github/workflows/check-bioc.yml
index 65610946..fab4d11a 100644
--- a/.github/workflows/check-bioc.yml
+++ b/.github/workflows/check-bioc.yml
@@ -52,7 +52,7 @@ jobs:
       fail-fast: false
       matrix:
         config:
-          - { os: ubuntu-latest, r: '4.4', bioc: '3.19', cont: "bioconductor/bioconductor_docker:devel", rspm: "https://packagemanager.rstudio.com/cran/__linux__/jammy/latest" }
+          - { os: ubuntu-latest, r: '4.5', bioc: '3.21', cont: "bioconductor/bioconductor_docker:devel", rspm: "https://packagemanager.rstudio.com/cran/__linux__/jammy/latest" }
           ## - { os: macOS-latest, r: '4.4', bioc: '3.19'}
           ## - { os: windows-latest, r: '4.4', bioc: '3.19'}
           ## Check https://github.com/r-lib/actions/tree/master/examples