diff --git a/.evergreen/buildvariants-and-tasks.in.yml b/.evergreen/buildvariants-and-tasks.in.yml
index 812a69fef2f..2501c5c1975 100644
--- a/.evergreen/buildvariants-and-tasks.in.yml
+++ b/.evergreen/buildvariants-and-tasks.in.yml
@@ -217,7 +217,7 @@ buildvariants:
 <% } %>
 
 <% for (const buildVariant of SMOKETEST_BUILD_VARIANTS) { %>
-<% for (const distribution of ['compass']) { %>
+<% for (const distribution of COMPASS_DISTRIBUTIONS) { %>
   - name: <%= buildVariant.name %>-<%= distribution %>
     display_name: <%= buildVariant.display_name %> (<%= distribution %>)
     run_on: <%= buildVariant.run_on %>
@@ -468,7 +468,7 @@ tasks:
           compass_distribution: <%= distribution %>
   <% } %>
 
-<% for (const distribution of ['compass']) { %>
+<% for (const distribution of COMPASS_DISTRIBUTIONS) { %>
   - name: smoketest-<%= distribution %>
     tags: ['required-for-publish', 'run-on-pr']
     commands:
diff --git a/.evergreen/buildvariants-and-tasks.yml b/.evergreen/buildvariants-and-tasks.yml
index 7612fdf3bc5..ee7fe4dc1cc 100644
--- a/.evergreen/buildvariants-and-tasks.yml
+++ b/.evergreen/buildvariants-and-tasks.yml
@@ -84,6 +84,22 @@ buildvariants:
         variant: package-ubuntu
     tasks:
       - name: smoketest-compass
+  - name: smoketest-ubuntu-compass-isolated
+    display_name: Smoketest Ubuntu (compass-isolated)
+    run_on: ubuntu2004-large
+    depends_on:
+      - name: package-compass-isolated
+        variant: package-ubuntu
+    tasks:
+      - name: smoketest-compass-isolated
+  - name: smoketest-ubuntu-compass-readonly
+    display_name: Smoketest Ubuntu (compass-readonly)
+    run_on: ubuntu2004-large
+    depends_on:
+      - name: package-compass-readonly
+        variant: package-ubuntu
+    tasks:
+      - name: smoketest-compass-readonly
   - name: smoketest-windows-compass
     display_name: Smoketest Windows (compass)
     run_on: windows-vsCurrent-large
@@ -92,6 +108,22 @@ buildvariants:
         variant: package-windows
     tasks:
       - name: smoketest-compass
+  - name: smoketest-windows-compass-isolated
+    display_name: Smoketest Windows (compass-isolated)
+    run_on: windows-vsCurrent-large
+    depends_on:
+      - name: package-compass-isolated
+        variant: package-windows
+    tasks:
+      - name: smoketest-compass-isolated
+  - name: smoketest-windows-compass-readonly
+    display_name: Smoketest Windows (compass-readonly)
+    run_on: windows-vsCurrent-large
+    depends_on:
+      - name: package-compass-readonly
+        variant: package-windows
+    tasks:
+      - name: smoketest-compass-readonly
   - name: smoketest-rhel-compass
     display_name: Smoketest RHEL (compass)
     run_on: rhel80-large
@@ -100,6 +132,22 @@ buildvariants:
         variant: package-rhel
     tasks:
       - name: smoketest-compass
+  - name: smoketest-rhel-compass-isolated
+    display_name: Smoketest RHEL (compass-isolated)
+    run_on: rhel80-large
+    depends_on:
+      - name: package-compass-isolated
+        variant: package-rhel
+    tasks:
+      - name: smoketest-compass-isolated
+  - name: smoketest-rhel-compass-readonly
+    display_name: Smoketest RHEL (compass-readonly)
+    run_on: rhel80-large
+    depends_on:
+      - name: package-compass-readonly
+        variant: package-rhel
+    tasks:
+      - name: smoketest-compass-readonly
   - name: smoketest-macos-x64-compass
     display_name: Smoketest MacOS Intel (compass)
     run_on: macos-14-gui
@@ -108,6 +156,22 @@ buildvariants:
         variant: package-macos-x64
     tasks:
       - name: smoketest-compass
+  - name: smoketest-macos-x64-compass-isolated
+    display_name: Smoketest MacOS Intel (compass-isolated)
+    run_on: macos-14-gui
+    depends_on:
+      - name: package-compass-isolated
+        variant: package-macos-x64
+    tasks:
+      - name: smoketest-compass-isolated
+  - name: smoketest-macos-x64-compass-readonly
+    display_name: Smoketest MacOS Intel (compass-readonly)
+    run_on: macos-14-gui
+    depends_on:
+      - name: package-compass-readonly
+        variant: package-macos-x64
+    tasks:
+      - name: smoketest-compass-readonly
   - name: smoketest-macos-arm-compass
     display_name: Smoketest MacOS Arm64 (compass)
     run_on: macos-14-arm64-gui
@@ -116,6 +180,22 @@ buildvariants:
         variant: package-macos-arm
     tasks:
       - name: smoketest-compass
+  - name: smoketest-macos-arm-compass-isolated
+    display_name: Smoketest MacOS Arm64 (compass-isolated)
+    run_on: macos-14-arm64-gui
+    depends_on:
+      - name: package-compass-isolated
+        variant: package-macos-arm
+    tasks:
+      - name: smoketest-compass-isolated
+  - name: smoketest-macos-arm-compass-readonly
+    display_name: Smoketest MacOS Arm64 (compass-readonly)
+    run_on: macos-14-arm64-gui
+    depends_on:
+      - name: package-compass-readonly
+        variant: package-macos-arm
+    tasks:
+      - name: smoketest-compass-readonly
   - name: test-eol-servers
     display_name: Test EoL Servers
     run_on: ubuntu1804-large
@@ -523,6 +603,36 @@ tasks:
           mongodb_version: 8.0.x-enterprise
           compass_distribution: compass
           debug: compass-e2e-tests*,electron*,hadron*,mongo*
+  - name: smoketest-compass-isolated
+    tags:
+      - required-for-publish
+      - run-on-pr
+    commands:
+      - func: prepare
+      - func: install
+      - func: bootstrap
+        vars:
+          scope: compass-e2e-tests
+      - func: smoketest-packaged-app
+        vars:
+          mongodb_version: 8.0.x-enterprise
+          compass_distribution: compass-isolated
+          debug: compass-e2e-tests*,electron*,hadron*,mongo*
+  - name: smoketest-compass-readonly
+    tags:
+      - required-for-publish
+      - run-on-pr
+    commands:
+      - func: prepare
+      - func: install
+      - func: bootstrap
+        vars:
+          scope: compass-e2e-tests
+      - func: smoketest-packaged-app
+        vars:
+          mongodb_version: 8.0.x-enterprise
+          compass_distribution: compass-readonly
+          debug: compass-e2e-tests*,electron*,hadron*,mongo*
   - name: test-server-40x-community-1
     tags:
       - required-for-publish
diff --git a/.evergreen/functions.yml b/.evergreen/functions.yml
index 70fd9ad2e46..49c897cd585 100644
--- a/.evergreen/functions.yml
+++ b/.evergreen/functions.yml
@@ -677,9 +677,19 @@ functions:
           npm i -w packages/compass-smoke-tests https://x-access-token:${generated_token}@github.com/10gen/compass-mongodb-com --engine-strict=false
 
           if [[ "$IS_WINDOWS" == "true" ]]; then
-            npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=windows_setup --tests time-to-first-query
-            npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=windows_zip --tests auto-update-from
-            npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=windows_msi --tests auto-update-from
+            if [[ "$HADRON_DISTRIBUTION" == "compass-readonly" ]]; then
+              npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=windows_setup --tests read-only
+            else
+              npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=windows_setup --tests time-to-first-query
+            fi
+            if [[ "$HADRON_DISTRIBUTION" == "compass-isolated" ]]; then
+              # auto-update is not supported on isolated
+              npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=windows_zip --tests time-to-first-query
+              npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=windows_msi --tests time-to-first-query
+            else
+              npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=windows_zip --tests auto-update-from
+              npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=windows_msi --tests auto-update-from
+            fi
           fi
 
           if [[ "$IS_OSX" == "true" ]]; then
@@ -688,18 +698,33 @@ functions:
             # NOTE: We're also skipping auto-update of the macOS app in CI
             # because it doesn't work. Running a different test to make sure it
             # can install and run successfully at least.
-            npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=osx_zip --tests=time-to-first-query
-            npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=osx_dmg --tests=time-to-first-query
+            if [[ "$HADRON_DISTRIBUTION" == "compass-readonly" ]]; then
+              npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=osx_zip --tests=read-only
+              npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=osx_dmg --tests=read-only
+            else
+              npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=osx_zip --tests=time-to-first-query
+              npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=osx_dmg --tests=time-to-first-query
+            fi
           fi
 
           if [[ "$IS_UBUNTU" == "true" ]]; then
-            npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=linux_deb --tests=time-to-first-query
-            npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=linux_tar --tests=time-to-first-query
+            if [[ "$HADRON_DISTRIBUTION" == "compass-readonly" ]]; then
+              npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=linux_deb --tests=read-only
+              npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=linux_tar --tests=read-only
+            else
+              npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=linux_deb --tests=time-to-first-query
+              npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=linux_tar --tests=time-to-first-query
+            fi
           fi
 
           if [[ "$IS_RHEL" == "true" ]]; then
-            npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=linux_rpm --tests=time-to-first-query
-            npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=linux_tar --tests=time-to-first-query
+            if [[ "$HADRON_DISTRIBUTION" == "compass-readonly" ]]; then
+              npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=linux_rpm --tests=read-only
+              npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=linux_tar --tests=read-only
+            else
+              npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=linux_rpm --tests=time-to-first-query
+              npm run --unsafe-perm --workspace @mongodb-js/compass-smoke-tests start -- --package=linux_tar --tests=time-to-first-query
+            fi
           fi
 
   test-web-sandbox:
diff --git a/packages/compass-smoke-tests/src/cli.ts b/packages/compass-smoke-tests/src/cli.ts
index da495021da4..3bca08581d0 100755
--- a/packages/compass-smoke-tests/src/cli.ts
+++ b/packages/compass-smoke-tests/src/cli.ts
@@ -7,6 +7,7 @@ import { SUPPORTED_TESTS } from './tests/types';
 import { type SmokeTestsContext } from './context';
 import { SUPPORTED_PACKAGES } from './packages';
 import { testTimeToFirstQuery } from './tests/time-to-first-query';
+import { testReadOnly } from './tests/read-only';
 import { testAutoUpdateFrom } from './tests/auto-update-from';
 import { testAutoUpdateTo } from './tests/auto-update-to';
 
@@ -126,6 +127,8 @@ async function run() {
 
     if (testName === 'time-to-first-query') {
       await testTimeToFirstQuery(context);
+    } else if (testName === 'read-only') {
+      await testReadOnly(context);
     } else if (testName === 'auto-update-from') {
       await testAutoUpdateFrom(context);
     } else if (testName === 'auto-update-to') {
diff --git a/packages/compass-smoke-tests/src/tests/read-only.ts b/packages/compass-smoke-tests/src/tests/read-only.ts
new file mode 100644
index 00000000000..3e93099d519
--- /dev/null
+++ b/packages/compass-smoke-tests/src/tests/read-only.ts
@@ -0,0 +1,57 @@
+import fs from 'node:fs';
+import { type SmokeTestsContext } from '../context';
+import { execute } from '../execute';
+import { getInstaller } from '../installers';
+import { createSandbox } from '../directories';
+import { getTestSubject } from '../test-subject';
+
+export async function testReadOnly(context: SmokeTestsContext) {
+  const sandboxPath = createSandbox();
+  const { kind, appName, filepath } = await getTestSubject({
+    ...context,
+    sandboxPath,
+  });
+
+  try {
+    const install = getInstaller(kind);
+
+    const { appPath, uninstall } = install({
+      appName,
+      filepath,
+      destinationPath: sandboxPath,
+    });
+
+    try {
+      execute(
+        'npm',
+        [
+          'run',
+          '--unsafe-perm',
+          'test-packaged',
+          '--workspace',
+          'compass-e2e-tests',
+          '--',
+          '--test-filter=read-only',
+        ],
+        {
+          // We need to use a shell to get environment variables setup correctly
+          shell: true,
+          env: {
+            ...process.env,
+            COMPASS_APP_NAME: appName,
+            COMPASS_APP_PATH: appPath,
+          },
+        }
+      );
+    } finally {
+      await uninstall();
+    }
+  } finally {
+    if (context.skipCleanup) {
+      console.log(`Skipped cleaning up sandbox: ${sandboxPath}`);
+    } else {
+      console.log(`Cleaning up sandbox: ${sandboxPath}`);
+      fs.rmSync(sandboxPath, { recursive: true });
+    }
+  }
+}
diff --git a/packages/compass-smoke-tests/src/tests/types.ts b/packages/compass-smoke-tests/src/tests/types.ts
index df5695dc8f9..8a0b28f4997 100644
--- a/packages/compass-smoke-tests/src/tests/types.ts
+++ b/packages/compass-smoke-tests/src/tests/types.ts
@@ -1,5 +1,6 @@
 export const SUPPORTED_TESTS = [
   'time-to-first-query',
+  'read-only',
   'auto-update-from',
   'auto-update-to',
 ] as const;