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<!DOCTYPE html>
<html>
<head>
<meta charset="utf-8" />
<meta name="description" content="PGxO">
<title>PGxO</title>
</head>
<body>
<h1>PGxO</h1>
<h2>Introduction</h2>
<p>
This document describes the namespace <a href="http://pgxo.loria.fr">http://pgxo.loria.fr/</a>.
The preferred prefix for this namespace is pgxo.
</p>
<p>
Content negotiation is supported for HTML and RDF/XML.
</p>
<p>
The OWL ontology file can be accessed directly from <a href="http://pgxo.loria.fr/data/pgxo.owl">http://pgxo.loria.fr/data/pgxo.owl</a>.
This URL should be used to import the ontology in another service, such as Protégé.
</p>
<p>
Documentation, examples and issue reporting can be found on
<a href="https://github.com/practikpharma/PGxO">GitHub</a>.<br />
A full description of the motivation, implementation and instantiation of PGxO
is available in the <a href="https://doi.org/10.1186/s12859-019-2693-9">related publication</a>.
</p>
<h2>Citing PGxO</h2>
<p>
When citing PGxO, please use the following reference:<br />
Monnin, P., Legrand, J., Husson, G., Ringot, P., Tchechmedjiev, A.,
Jonquet, C., Napoli, A., & Coulet, A.
PGxO and PGxLOD: a reconciliation of pharmacogenomic knowledge of various provenances,
enabling further comparison. BMC Bioinformatics 20-S(4): 139:1-139:16 (2019).
</p>
<pre><code>
@Article{Monnin2019,
author="Monnin, Pierre
and Legrand, Jo{\"e}l
and Husson, Graziella
and Ringot, Patrice
and Tchechmedjiev, Andon
and Jonquet, Cl{\'e}ment
and Napoli, Amedeo
and Coulet, Adrien",
title="PGxO and PGxLOD: a reconciliation of pharmacogenomic knowledge of various provenances, enabling further comparison",
journal="BMC Bioinformatics",
year="2019",
month="Apr",
day="18",
volume="20-S",
number="4",
pages="139",
issn="1471-2105",
doi="10.1186/s12859-019-2693-9",
url="https://doi.org/10.1186/s12859-019-2693-9"
}
</code></pre>
<h2>Index</h2>
<h3 id="causes">causes</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/causes">http://pgxo.loria.fr/causes</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/influences">influences</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/isCausedBy">isCausedBy</a></p>
<h3 id="decreases">decreases</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/decreases">http://pgxo.loria.fr/decreases</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/influences">influences</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/isDecreasedBy">isDecreasedBy</a></p>
<h3 id="decreasesChanceOf">decreasesChanceOf</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/decreasesChanceOf">http://pgxo.loria.fr/decreasesChanceOf</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/influences">influences</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/hasChanceDecreasedBy">hasChanceDecreasedBy</a></p>
<h3 id="Disease">Disease</h3>
<p>Class</p>
<p>URI: <a href="http://pgxo.loria.fr/Disease">http://pgxo.loria.fr/Disease</a></p>
<p>Subclass of: <a href="http://pgxo.loria.fr/Phenotype">Phenotype</a></p>
<h3 id="doesNotCause">doesNotCause</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/doesNotCause">http://pgxo.loria.fr/doesNotCause</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/doesNotInfluence">doesNotInfluence</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/isNotCausedBy">isNotCausedBy</a></p>
<h3 id="doesNotDecrease">doesNotDecrease</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/doesNotDecrease">http://pgxo.loria.fr/doesNotDecrease</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/doesNotInfluence">doesNotInfluence</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/isNotDecreasedBy">isNotDecreasedBy</a></p>
<h3 id="doesNotDecreaseChanceOf">doesNotDecreaseChanceOf</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/doesNotDecreaseChanceOf">http://pgxo.loria.fr/doesNotDecreaseChanceOf</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/doesNotInfluence">doesNotInfluence</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/hasNotChanceDecreasedBy">hasNotChanceDecreasedBy</a></p>
<h3 id="doesNotIncrease">doesNotIncrease</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/doesNotIncrease">http://pgxo.loria.fr/doesNotIncrease</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/doesNotInfluence">doesNotInfluence</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/isNotIncreasedBy">isNotIncreasedBy</a></p>
<h3 id="doesNotIncreaseChanceOf">doesNotIncreaseChanceOf</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/doesNotIncreaseChanceOf">http://pgxo.loria.fr/doesNotIncreaseChanceOf</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/doesNotInfluence">doesNotInfluence</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/hasNotChanceIncreasedBy">hasNotChanceIncreasedBy</a></p>
<h3 id="doesNotInfluence">doesNotInfluence</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/doesNotInfluence">http://pgxo.loria.fr/doesNotInfluence</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isNotAssociatedWith">isNotAssociatedWith</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/isNotInfluencedBy">isNotInfluencedBy</a></p>
<h3 id="doesNotMetabolize">doesNotMetabolize</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/doesNotMetabolize">http://pgxo.loria.fr/doesNotMetabolize</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/doesNotInfluence">doesNotInfluence</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/isNotMetabolizedBy">isNotMetabolizedBy</a></p>
<h3 id="doesNotTransport">doesNotTransport</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/doesNotTransport">http://pgxo.loria.fr/doesNotTransport</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/doesNotInfluence">doesNotInfluence</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/isNotTransportedBy">isNotTransportedBy</a></p>
<h3 id="doesNotTreat">doesNotTreat</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/doesNotTreat">http://pgxo.loria.fr/doesNotTreat</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isNotAssociatedWith">isNotAssociatedWith</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/isNotTreatedBy">isNotTreatedBy</a></p>
<h3 id="Drug">Drug</h3>
<p>Class</p>
<p>URI: <a href="http://pgxo.loria.fr/Drug">http://pgxo.loria.fr/Drug</a></p>
<h3 id="Gene">Gene</h3>
<p>Class</p>
<p>URI: <a href="http://pgxo.loria.fr/Gene">http://pgxo.loria.fr/Gene</a></p>
<p>Subclass of: <a href="http://pgxo.loria.fr/GeneticFactor">Genetic factor</a></p>
<h3 id="GeneticFactor">Genetic factor</h3>
<p>Class</p>
<p>URI: <a href="http://pgxo.loria.fr/GeneticFactor">http://pgxo.loria.fr/GeneticFactor</a></p>
<h3 id="GenomicVariation">Genomic variation</h3>
<p>Class</p>
<p>URI: <a href="http://pgxo.loria.fr/GenomicVariation">http://pgxo.loria.fr/GenomicVariation</a></p>
<p>Subclass of: <a href="http://pgxo.loria.fr/GeneticFactor">Genetic factor</a></p>
<h3 id="Haplotype">Haplotype</h3>
<p>Class</p>
<p>URI: <a href="http://pgxo.loria.fr/Haplotype">http://pgxo.loria.fr/Haplotype</a></p>
<p>Subclass of: <a href="http://pgxo.loria.fr/GenomicVariation">Genomic variation</a></p>
<h3 id="hasChanceDecreasedBy">hasChanceDecreasedBy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/hasChanceDecreasedBy">http://pgxo.loria.fr/hasChanceDecreasedBy</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isInfluencedBy">isInfluencedBy</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/decreasesChanceOf">decreasesChanceOf</a></p>
<h3 id="hasChanceIncreasedBy">hasChanceIncreasedBy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/hasChanceIncreasedBy">http://pgxo.loria.fr/hasChanceIncreasedBy</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isInfluencedBy">isInfluencedBy</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/increasesChanceOf">increasesChanceOf</a></p>
<h3 id="hasNotChanceDecreasedBy">hasNotChanceDecreasedBy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/hasNotChanceDecreasedBy">http://pgxo.loria.fr/hasNotChanceDecreasedBy</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isNotInfluencedBy">isNotInfluencedBy</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/doesNotDecreaseChanceOf">doesNotDecreaseChanceOf</a></p>
<h3 id="hasNotChanceIncreasedBy">hasNotChanceIncreasedBy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/hasNotChanceIncreasedBy">http://pgxo.loria.fr/hasNotChanceIncreasedBy</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isNotInfluencedBy">isNotInfluencedBy</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/doesNotIncreaseChanceOf">doesNotIncreaseChanceOf</a></p>
<h3 id="increases">increases</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/increases">http://pgxo.loria.fr/increases</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/influences">influences</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/isIncreasedBy">isIncreasedBy</a></p>
<h3 id="increasesChanceOf">increasesChanceOf</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/increasesChanceOf">http://pgxo.loria.fr/increasesChanceOf</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/influences">influences</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/hasChanceIncreasedBy">hasChanceIncreasedBy</a></p>
<h3 id="influences">influences</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/influences">http://pgxo.loria.fr/influences</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isAssociatedWith">isAssociatedWith</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/isInfluencedBy">isInfluencedBy</a></p>
<h3 id="isAssociatedWith">isAssociatedWith</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/isAssociatedWith">http://pgxo.loria.fr/isAssociatedWith</a></p>
<p>Symmetric property</p>
<h3 id="isCausedBy">isCausedBy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/isCausedBy">http://pgxo.loria.fr/isCausedBy</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isInfluencedBy">isInfluencedBy</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/causes">causes</a></p>
<h3 id="isDecreasedBy">isDecreasedBy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/isDecreasedBy">http://pgxo.loria.fr/isDecreasedBy</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isInfluencedBy">isInfluencedBy</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/decreases">decreases</a></p>
<h3 id="isIncreasedBy">isIncreasedBy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/isIncreasedBy">http://pgxo.loria.fr/isIncreasedBy</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isInfluencedBy">isInfluencedBy</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/increases">increases</a></p>
<h3 id="isInfluencedBy">isInfluencedBy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/isInfluencedBy">http://pgxo.loria.fr/isInfluencedBy</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isAssociatedWith">isAssociatedWith</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/influences">influences</a></p>
<h3 id="isMetabolizedBy">isMetabolizedBy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/isMetabolizedBy">http://pgxo.loria.fr/isMetabolizedBy</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isInfluencedBy">isInfluencedBy</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/metabolizes">metabolizes</a></p>
<h3 id="isNotAssociatedWith">isNotAssociatedWith</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/isNotAssociatedWith">http://pgxo.loria.fr/isNotAssociatedWith</a></p>
<p>Symmetric property</p>
<h3 id="isNotCausedBy">isNotCausedBy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/isNotCausedBy">http://pgxo.loria.fr/isNotCausedBy</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isNotInfluencedBy">isNotInfluencedBy</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/doesNotCause">doesNotCause</a></p>
<h3 id="isNotDecreasedBy">isNotDecreasedBy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/isNotDecreasedBy">http://pgxo.loria.fr/isNotDecreasedBy</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isNotInfluencedBy">isNotInfluencedBy</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/doesNotDecrease">doesNotDecrease</a></p>
<h3 id="isNotIncreasedBy">isNotIncreasedBy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/isNotIncreasedBy">http://pgxo.loria.fr/isNotIncreasedBy</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isNotInfluencedBy">isNotInfluencedBy</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/doesNotIncrease">doesNotIncrease</a></p>
<h3 id="isNotInfluencedBy">isNotInfluencedBy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/isNotInfluencedBy">http://pgxo.loria.fr/isNotInfluencedBy</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isNotAssociatedWith">isNotAssociatedWith</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/doesNotInfluence">doesNotInfluence</a></p>
<h3 id="isNotMetabolizedBy">isNotMetabolizedBy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/isNotMetabolizedBy">http://pgxo.loria.fr/isNotMetabolizedBy</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isNotInfluencedBy">isNotInfluencedBy</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/doesNotMetabolize">doesNotMetabolize</a></p>
<h3 id="isNotTransportedBy">isNotTransportedBy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/isNotTransportedBy">http://pgxo.loria.fr/isNotTransportedBy</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isNotInfluencedBy">isNotInfluencedBy</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/doesNotTransport">doesNotTransport</a></p>
<h3 id="isNotTreatedBy">isNotTreatedBy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/isNotTreatedBy">http://pgxo.loria.fr/isNotTreatedBy</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isNotAssociatedWith">isNotAssociatedWith</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/doesNotTreat">doesNotTreat</a></p>
<h3 id="isTransportedBy">isTransportedBy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/isTransportedBy">http://pgxo.loria.fr/isTransportedBy</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isInfluencedBy">isInfluencedBy</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/transports">transports</a></p>
<h3 id="isTreatedBy">isTreatedBy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/isTreatedBy">http://pgxo.loria.fr/isTreatedBy</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isAssociatedWith">isAssociatedWith</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/treats">treats</a></p>
<h3 id="metabolizes">metabolizes</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/metabolizes">http://pgxo.loria.fr/metabolizes</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/influences">influences</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/isMetabolizedBy">isMetabolizedBy</a></p>
<h3 id="PharmacodynamicPhenotype">Pharmacodynamic phenotype</h3>
<p>Class</p>
<p>URI: <a href="http://pgxo.loria.fr/PharmacodynamicPhenotype">http://pgxo.loria.fr/PharmacodynamicPhenotype</a></p>
<p>Subclass of: <a href="http://pgxo.loria.fr/Phenotype">Phenotype</a></p>
<h3 id="PharmacogenomicRelationship">Pharmacogenomic relationship</h3>
<p>Class</p>
<p>URI: <a href="http://pgxo.loria.fr/PharmacogenomicRelationship">http://pgxo.loria.fr/PharmacogenomicRelationship</a></p>
<p>Subclass of: <a href="http://www.w3.org/ns/prov#Entity">prov:Entity</a></p>
<h3 id="PharmacokineticPhenotype">Pharmacokinetic phenotype</h3>
<p>Class</p>
<p>URI: <a href="http://pgxo.loria.fr/PharmacokineticPhenotype">http://pgxo.loria.fr/PharmacokineticPhenotype</a></p>
<p>Subclass of: <a href="http://pgxo.loria.fr/Phenotype">Phenotype</a></p>
<h3 id="Phenotype">Phenotype</h3>
<p>Class</p>
<p>URI: <a href="http://pgxo.loria.fr/Phenotype">http://pgxo.loria.fr/Phenotype</a></p>
<h3 id="qualifiedProxy">qualifiedProxy</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/qualifiedProxy">http://pgxo.loria.fr/qualifiedProxy</a></p>
<h3 id="qualifiedVariation">qualifiedVariation</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/qualifiedVariation">http://pgxo.loria.fr/qualifiedVariation</a></p>
<h3 id="transports">transports</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/transports">http://pgxo.loria.fr/transports</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/influences">influences</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/isTransportedBy">isTransportedBy</a></p>
<h3 id="treats">treats</h3>
<p>Object property</p>
<p>URI: <a href="http://pgxo.loria.fr/treats">http://pgxo.loria.fr/treats</a></p>
<p>Subproperty of: <a href="http://pgxo.loria.fr/isAssociatedWith">isAssociatedWith</a></p>
<p>Inverse of: <a href="http://pgxo.loria.fr/isTreatedBy">isTreatedBy</a></p>
<h3 id="Variant">Variant</h3>
<p>Class</p>
<p>URI: <a href="http://pgxo.loria.fr/Variant">http://pgxo.loria.fr/Variant</a></p>
<p>Subclass of: <a href="http://pgxo.loria.fr/GenomicVariation">Genomic variation</a></p>
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