diff --git a/src/tools/compiletest/src/directives.rs b/src/tools/compiletest/src/directives.rs
index 93133ea0bfd2e..75c11c31e493a 100644
--- a/src/tools/compiletest/src/directives.rs
+++ b/src/tools/compiletest/src/directives.rs
@@ -854,6 +854,7 @@ const KNOWN_DIRECTIVE_NAMES: &[&str] = &[
     "ignore-openbsd",
     "ignore-pass",
     "ignore-powerpc",
+    "ignore-powerpc64",
     "ignore-remote",
     "ignore-riscv64",
     "ignore-rustc-debug-assertions",
diff --git a/tests/debuginfo/basic-types-globals-metadata.rs b/tests/debuginfo/basic-types-globals-metadata.rs
index 53fc550a2dc8c..aec8ff183ad75 100644
--- a/tests/debuginfo/basic-types-globals-metadata.rs
+++ b/tests/debuginfo/basic-types-globals-metadata.rs
@@ -59,7 +59,12 @@ static mut F64: f64 = 3.5;
 fn main() {
     _zzz(); // #break
 
-    let a = unsafe { (B, I, C, I8, I16, I32, I64, U, U8, U16, U32, U64, F16, F32, F64) };
+    let a = unsafe { (B, I, C, I8, I16, I32, I64, U, U8, U16, U32, U64, F32, F64) };
+    // FIXME: Including f16 and f32 in the same tuple emits `__gnu_h2f_ieee`, which
+    // does not exist on some targets like PowerPC.
+    // See https://github.com/llvm/llvm-project/issues/97981 and
+    // https://github.com/rust-lang/compiler-builtins/issues/655
+    let b = unsafe { F16 };
 }
 
 fn _zzz() {()}
diff --git a/tests/debuginfo/basic-types-globals.rs b/tests/debuginfo/basic-types-globals.rs
index 41b69939650da..15a0deb64c125 100644
--- a/tests/debuginfo/basic-types-globals.rs
+++ b/tests/debuginfo/basic-types-globals.rs
@@ -63,7 +63,12 @@ static mut F64: f64 = 3.5;
 fn main() {
     _zzz(); // #break
 
-    let a = unsafe { (B, I, C, I8, I16, I32, I64, U, U8, U16, U32, U64, F16, F32, F64) };
+    let a = unsafe { (B, I, C, I8, I16, I32, I64, U, U8, U16, U32, U64, F32, F64) };
+    // FIXME: Including f16 and f32 in the same tuple emits `__gnu_h2f_ieee`, which
+    // does not exist on some targets like PowerPC.
+    // See https://github.com/llvm/llvm-project/issues/97981 and
+    // https://github.com/rust-lang/compiler-builtins/issues/655
+    let b = unsafe { F16 };
 }
 
 fn _zzz() {()}
diff --git a/tests/debuginfo/by-value-non-immediate-argument.rs b/tests/debuginfo/by-value-non-immediate-argument.rs
index 5233b95f1f4ad..deacea5f6ccd8 100644
--- a/tests/debuginfo/by-value-non-immediate-argument.rs
+++ b/tests/debuginfo/by-value-non-immediate-argument.rs
@@ -3,6 +3,7 @@
 //@ compile-flags:-g
 //@ ignore-windows-gnu: #128973
 //@ ignore-aarch64-unknown-linux-gnu (gdb tries to read from 0x0; FIXME: #128973)
+//@ ignore-powerpc64: #128973 on both -gnu and -musl
 
 // === GDB TESTS ===================================================================================