diff --git a/packages/node-core/src/indexer/dynamic-ds.service.spec.ts b/packages/node-core/src/indexer/dynamic-ds.service.spec.ts
index c56aa05927..479efbd522 100644
--- a/packages/node-core/src/indexer/dynamic-ds.service.spec.ts
+++ b/packages/node-core/src/indexer/dynamic-ds.service.spec.ts
@@ -15,8 +15,8 @@ class TestDynamicDsService extends DynamicDsService<BaseDataSource, ISubqueryPro
   }
 
   // Make it public
-  getTemplate(templateName: string, startBlock?: number | undefined): BaseDataSource {
-    return super.getTemplate(templateName, startBlock);
+  getTemplate(templateName: string, startBlock?: number | undefined, endBlock?: number | undefined): BaseDataSource {
+    return super.getTemplate(templateName, startBlock, endBlock);
   }
 }
 
@@ -24,6 +24,7 @@ const testParam1 = {templateName: 'Test', startBlock: 1};
 const testParam2 = {templateName: 'Test', startBlock: 2};
 const testParam3 = {templateName: 'Test', startBlock: 3};
 const testParam4 = {templateName: 'Test', startBlock: 4};
+const testParamOther = {templateName: 'Other', startBlock: 5};
 
 const mockMetadata = (initData: DatasourceParams[] = []) => {
   let datasourceParams: DatasourceParams[] = initData;
@@ -40,7 +41,7 @@ const mockMetadata = (initData: DatasourceParams[] = []) => {
 describe('DynamicDsService', () => {
   let service: TestDynamicDsService;
   const project = {
-    templates: [{name: 'Test'}],
+    templates: [{name: 'Test'}, {name: 'Other'}],
   } as any as ISubqueryProject;
 
   beforeEach(() => {
@@ -70,6 +71,67 @@ describe('DynamicDsService', () => {
     ]);
   });
 
+  it('can destroy a dynamic datasource', async () => {
+    const meta = mockMetadata([testParam1, testParam2]);
+    await service.init(meta);
+
+    await service.destroyDynamicDatasource('Test', 50);
+
+    const updatedParams = (service as any)._datasourceParams;
+    expect(updatedParams[0]).toEqual({...testParam1, endBlock: 50});
+    expect(updatedParams[1]).toEqual(testParam2);
+
+    const datasources = (service as any)._datasources;
+    expect(datasources[0].endBlock).toBe(50);
+  });
+
+  it('throws error when destroying non-existent datasource', async () => {
+    const meta = mockMetadata([testParam1]);
+    await service.init(meta);
+
+    await expect(service.destroyDynamicDatasource('NonExistent', 50)).rejects.toThrow(
+      'Dynamic datasource with template name "NonExistent" not found'
+    );
+  });
+
+  it('throws error when destroying already destroyed datasource', async () => {
+    const destroyedParam = {...testParam1, endBlock: 30};
+    const meta = mockMetadata([destroyedParam]);
+    await service.init(meta);
+
+    await expect(service.destroyDynamicDatasource('Test', 50)).rejects.toThrow(
+      'Dynamic datasource "Test" is already destroyed'
+    );
+  });
+
+  it('allows creating new datasource after destroying existing one', async () => {
+    const meta = mockMetadata([testParam1]);
+    await service.init(meta);
+
+    expect((service as any)._datasourceParams).toEqual([testParam1]);
+
+    await service.destroyDynamicDatasource('Test', 50);
+
+    const paramsAfterDestroy = (service as any)._datasourceParams;
+    expect(paramsAfterDestroy[0]).toEqual({...testParam1, endBlock: 50});
+
+    const newParam = {templateName: 'Test', startBlock: 60};
+    await service.createDynamicDatasource(newParam);
+
+    const finalParams = (service as any)._datasourceParams;
+    const destroyedCount = finalParams.filter((p) => p.endBlock !== undefined).length;
+    const activeCount = finalParams.filter((p) => p.endBlock === undefined).length;
+
+    expect(destroyedCount).toBeGreaterThanOrEqual(1);
+    expect(activeCount).toBeGreaterThanOrEqual(1);
+
+    const destroyedParam = finalParams.find((p) => p.startBlock === 1 && p.endBlock === 50);
+    expect(destroyedParam).toBeDefined();
+
+    const newParamFound = finalParams.find((p) => p.startBlock === 60 && !p.endBlock);
+    expect(newParamFound).toBeDefined();
+  });
+
   it('resets dynamic datasources', async () => {
     const meta = mockMetadata([testParam1, testParam2, testParam3, testParam4]);
     await service.init(meta);
@@ -83,6 +145,25 @@ describe('DynamicDsService', () => {
     ]);
   });
 
+  it('handles reset after datasource destruction correctly', async () => {
+    const params = [testParam1, testParam2, testParam3, testParam4];
+    const meta = mockMetadata(params);
+    await service.init(meta);
+
+    await service.destroyDynamicDatasource('Test', 25); // Destroys testParam1
+
+    const paramsAfterDestroy = (service as any)._datasourceParams;
+    expect(paramsAfterDestroy[0]).toEqual({...testParam1, endBlock: 25});
+
+    // Reset to block 2 (should keep testParam1 and testParam2)
+    await service.resetDynamicDatasource(2, null as any);
+
+    const paramsAfterReset = (service as any)._datasourceParams;
+    expect(paramsAfterReset).toHaveLength(2);
+    expect(paramsAfterReset[0]).toEqual({...testParam1, endBlock: 25});
+    expect(paramsAfterReset[1]).toEqual(testParam2);
+  });
+
   it('getDynamicDatasources with force reloads from metadata', async () => {
     const meta = mockMetadata([testParam1, testParam2]);
     await service.init(meta);
@@ -107,6 +188,29 @@ describe('DynamicDsService', () => {
     ]);
   });
 
+  it('loads destroyed datasources with endBlock correctly', async () => {
+    const destroyedParam = {...testParam1, endBlock: 100};
+    const meta = mockMetadata([destroyedParam, testParam2]);
+    await service.init(meta);
+
+    const datasources = await service.getDynamicDatasources();
+    expect(datasources).toHaveLength(2);
+    expect((datasources[0] as any).endBlock).toBe(100);
+    expect((datasources[1] as any).endBlock).toBeUndefined();
+  });
+
+  it('updates metadata correctly when destroying datasource', async () => {
+    const meta = mockMetadata([testParam1, testParam2]);
+    await service.init(meta);
+
+    await service.destroyDynamicDatasource('Test', 75);
+
+    const metadataParams = await meta.find('dynamicDatasources');
+    expect(metadataParams).toBeDefined();
+    expect(metadataParams![0]).toEqual({...testParam1, endBlock: 75});
+    expect(metadataParams![1]).toEqual(testParam2);
+  });
+
   it('can find a template and cannot mutate the template', () => {
     const template1 = service.getTemplate('Test', 1);
     const template2 = service.getTemplate('Test', 2);
@@ -120,4 +224,35 @@ describe('DynamicDsService', () => {
     // eslint-disable-next-line @typescript-eslint/no-non-null-assertion
     expect(project.templates![0]).toEqual({name: 'Test'});
   });
+
+  it('can create template with endBlock', () => {
+    const template = service.getTemplate('Test', 1, 100);
+
+    expect(template.startBlock).toBe(1);
+    expect((template as any).endBlock).toBe(100);
+    expect((template as any).name).toBeUndefined();
+  });
+
+  it('handles multiple templates with same name during destruction', async () => {
+    const param1 = {templateName: 'Test', startBlock: 1};
+    const param2 = {templateName: 'Test', startBlock: 5};
+    const param3 = {templateName: 'Other', startBlock: 3};
+
+    const meta = mockMetadata([param1, param2, param3]);
+    await service.init(meta);
+
+    // Should destroy the first matching one
+    await service.destroyDynamicDatasource('Test', 10);
+
+    const updatedParams = (service as any)._datasourceParams;
+    expect(updatedParams[0]).toEqual({...param1, endBlock: 10});
+    expect(updatedParams[1]).toEqual(param2); // Not destroyed
+    expect(updatedParams[2]).toEqual(param3); // Not destroyed
+  });
+
+  it('throws error when service not initialized for destruction', async () => {
+    await expect(service.destroyDynamicDatasource('Test', 50)).rejects.toThrow(
+      'DynamicDsService has not been initialized'
+    );
+  });
 });
diff --git a/packages/node-core/src/indexer/dynamic-ds.service.ts b/packages/node-core/src/indexer/dynamic-ds.service.ts
index 708ab5f3bb..17a309d22b 100644
--- a/packages/node-core/src/indexer/dynamic-ds.service.ts
+++ b/packages/node-core/src/indexer/dynamic-ds.service.ts
@@ -19,11 +19,13 @@ export interface DatasourceParams {
   templateName: string;
   args?: Record<string, unknown>;
   startBlock: number;
+  endBlock?: number;
 }
 
 export interface IDynamicDsService<DS> {
   dynamicDatasources: DS[];
   createDynamicDatasource(params: DatasourceParams): Promise<DS>;
+  destroyDynamicDatasource(templateName: string, currentBlockHeight: number): Promise<void>;
   getDynamicDatasources(forceReload?: boolean): Promise<DS[]>;
 }
 
@@ -91,6 +93,34 @@ export class DynamicDsService<DS extends BaseDataSource = BaseDataSource, P exte
     }
   }
 
+  async destroyDynamicDatasource(templateName: string, currentBlockHeight: number, tx?: Transaction): Promise<void> {
+    if (!this._datasources || !this._datasourceParams) {
+      throw new Error('DynamicDsService has not been initialized');
+    }
+
+    const dsIndex = this._datasourceParams.findIndex((params) => params.templateName === templateName);
+    if (dsIndex === -1) {
+      throw new Error(`Dynamic datasource with template name "${templateName}" not found`);
+    }
+
+    const dsParam = this._datasourceParams[dsIndex];
+
+    if (dsParam.endBlock !== undefined) {
+      throw new Error(`Dynamic datasource "${templateName}" is already destroyed`);
+    }
+
+    const updatedParams = {...dsParam, endBlock: currentBlockHeight};
+    this._datasourceParams[dsIndex] = updatedParams;
+
+    if (this._datasources[dsIndex]) {
+      (this._datasources[dsIndex] as any).endBlock = currentBlockHeight;
+    }
+
+    await this.metadata.set(METADATA_KEY, this._datasourceParams, tx);
+
+    logger.info(`Destroyed dynamic datasource "${templateName}" at block ${currentBlockHeight}`);
+  }
+
   // Not force only seems to be used for project changes
   async getDynamicDatasources(forceReload?: boolean): Promise<DS[]> {
     // Workers should not cache this result in order to keep in sync
@@ -117,19 +147,19 @@ export class DynamicDsService<DS extends BaseDataSource = BaseDataSource, P exte
    *
    * This will throw if the template cannot be found by name.
    *
-   * Inserts the startBlock into the template.
+   * Inserts the startBlock and optionally endBlock into the template.
    * */
-  protected getTemplate(templateName: string, startBlock?: number): DS {
+  protected getTemplate(templateName: string, startBlock?: number, endBlock?: number): DS {
     const t = (this.project.templates ?? []).find((t) => t.name === templateName);
     if (!t) {
       throw new Error(`Unable to find matching template in project for name: "${templateName}"`);
     }
     const {name, ...template} = cloneDeep(t);
-    return {...template, startBlock} as DS;
+    return {...template, startBlock, endBlock} as DS;
   }
 
   private async getDatasource(params: DatasourceParams): Promise<DS> {
-    const dsObj = this.getTemplate(params.templateName, params.startBlock);
+    const dsObj = this.getTemplate(params.templateName, params.startBlock, params.endBlock);
 
     try {
       await this.blockchainService.updateDynamicDs(params, dsObj);
diff --git a/packages/node-core/src/indexer/indexer.manager.ts b/packages/node-core/src/indexer/indexer.manager.ts
index 9400f3707f..6d9b954993 100644
--- a/packages/node-core/src/indexer/indexer.manager.ts
+++ b/packages/node-core/src/indexer/indexer.manager.ts
@@ -116,6 +116,29 @@ export abstract class BaseIndexerManager<
           dynamicDsCreated = true;
         }, 'createDynamicDatasource');
 
+        // Inject function to destroy ds into vm
+        vm.freeze(async (templateName?: string) => {
+          if (!templateName) {
+            throw new Error('Cannot destroy datasource: template name must be provided');
+          }
+
+          await this.dynamicDsService.destroyDynamicDatasource(templateName, blockHeight);
+
+          // Mark datasources with this template for removal from current processing
+          filteredDataSources.forEach((fds) => {
+            const dsParams = this.dynamicDsService.dynamicDatasources.find((dynamicDs) => {
+              // Find the corresponding params for this datasource
+              const params = (this.dynamicDsService as any)._datasourceParams?.find(
+                (p: any) => p.templateName === templateName && p.startBlock === (fds as any).startBlock
+              );
+              return params !== undefined;
+            });
+            if (dsParams) {
+              (fds as any).endBlock = blockHeight;
+            }
+          });
+        }, 'destroyDynamicDatasource');
+
         return vm;
       });
     }
diff --git a/packages/node-core/src/indexer/worker/worker.dynamic-ds.service.ts b/packages/node-core/src/indexer/worker/worker.dynamic-ds.service.ts
index 3c6e456a08..3e09bfc070 100644
--- a/packages/node-core/src/indexer/worker/worker.dynamic-ds.service.ts
+++ b/packages/node-core/src/indexer/worker/worker.dynamic-ds.service.ts
@@ -7,11 +7,13 @@ import {DatasourceParams, IDynamicDsService} from '../dynamic-ds.service';
 
 export type HostDynamicDS<DS> = {
   dynamicDsCreateDynamicDatasource: (params: DatasourceParams) => Promise<DS>;
+  dynamicDsDestroyDynamicDatasource: (templateName: string, currentBlockHeight: number) => Promise<void>;
   dynamicDsGetDynamicDatasources: () => Promise<DS[]>;
 };
 
 export const hostDynamicDsKeys: (keyof HostDynamicDS<any>)[] = [
   'dynamicDsCreateDynamicDatasource',
+  'dynamicDsDestroyDynamicDatasource',
   'dynamicDsGetDynamicDatasources',
 ];
 
@@ -32,6 +34,10 @@ export class WorkerDynamicDsService<DS> implements IDynamicDsService<DS> {
     return this.host.dynamicDsCreateDynamicDatasource(JSON.parse(JSON.stringify(params)));
   }
 
+  async destroyDynamicDatasource(templateName: string, currentBlockHeight: number): Promise<void> {
+    return this.host.dynamicDsDestroyDynamicDatasource(templateName, currentBlockHeight);
+  }
+
   async getDynamicDatasources(): Promise<DS[]> {
     return this.host.dynamicDsGetDynamicDatasources();
   }
@@ -40,6 +46,7 @@ export class WorkerDynamicDsService<DS> implements IDynamicDsService<DS> {
 export function dynamicDsHostFunctions<DS>(dynamicDsService: IDynamicDsService<DS>): HostDynamicDS<DS> {
   return {
     dynamicDsCreateDynamicDatasource: dynamicDsService.createDynamicDatasource.bind(dynamicDsService),
+    dynamicDsDestroyDynamicDatasource: dynamicDsService.destroyDynamicDatasource.bind(dynamicDsService),
     dynamicDsGetDynamicDatasources: dynamicDsService.getDynamicDatasources.bind(dynamicDsService),
   };
 }
diff --git a/packages/types-core/src/global.ts b/packages/types-core/src/global.ts
index cbaf1be173..66d1c33861 100644
--- a/packages/types-core/src/global.ts
+++ b/packages/types-core/src/global.ts
@@ -2,7 +2,7 @@
 // SPDX-License-Identifier: GPL-3.0
 
 import type Pino from 'pino';
-import {Cache, DynamicDatasourceCreator} from './interfaces';
+import {Cache, DynamicDatasourceCreator, DynamicDatasourceDestructor} from './interfaces';
 import {Store} from './store';
 
 // base global
@@ -12,4 +12,5 @@ declare global {
   const cache: Cache;
   const chainId: string;
   const createDynamicDatasource: DynamicDatasourceCreator;
+  const destroyDynamicDatasource: DynamicDatasourceDestructor;
 }
diff --git a/packages/types-core/src/interfaces.ts b/packages/types-core/src/interfaces.ts
index bde78e77ac..28e1406103 100644
--- a/packages/types-core/src/interfaces.ts
+++ b/packages/types-core/src/interfaces.ts
@@ -2,6 +2,7 @@
 // SPDX-License-Identifier: GPL-3.0
 
 export type DynamicDatasourceCreator = (name: string, args: Record<string, unknown>) => Promise<void>;
+export type DynamicDatasourceDestructor = (name?: string) => Promise<void>;
 
 export interface Cache<T extends Record<string, any> = Record<string, any>> {
   set(key: keyof T, value: T[keyof T]): Promise<void>;