When installing guv system-wide and trying to import it afterwards as a user I get the following error message: PermissionError: [Errno 13] Permission denied: '/usr/lib/python3.4/site-packages/pyuv_cffi/__pycache__/_cffi__x9bdc36e8xf9520033.c'
The .c file and also the .so file is generated upon setup.py install, they are not copied to the install destination though. Thus, cffi tries to build it but lacks permission to write to the system directory.