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24 changes: 14 additions & 10 deletions readme.txt → readme.md
Original file line number Diff line number Diff line change
@@ -1,33 +1,37 @@
NEURON mod files for the Na, K-A, and K-DR currents from the paper:
Safronov and Vogel, J.Physiol. 487:91-106 (1995).
Safronov and Vogel, *J.Physiol*. 487:91-106 (1995).

Running the kinetics_na.hoc or kinetics_k.hoc simulation files
- Running the kinetics_na.hoc or kinetics_k.hoc simulation files
will show the activation and inactivation steady-states,
the time constants, and a family of curves generated modeling
the same protocols used in the paper.

Markers show the experimental values estimated from Figs.4C
- Markers show the experimental values estimated from Figs.4C
(Na), 8C (KA), and 10C (KDR) of the paper.
Note that m is used rather than the more usual m^3 for activation
of the Na current. Na recovery from inactivation is not implemented.

Under unix systems:
## Under unix systems:
to compile the mod files use the command
nrnivmodl
``` nrnivmodl ```
and run the simulation hoc file with the command
nrngui kinetics_na.hoc
``` nrngui kinetics_na.hoc ```
or
nrngui kinetics_k.hoc
``` nrngui kinetics_k.hoc ```


Under Windows using NEURON 5.1:
to compile the mod files use the "mknrndll" command.
## Under Windows using NEURON 5.1:
to compile the mod files use the ``` mknrndll ``` command.
A double click on the simulation files
kinetics_na.hoc or kinetics_k.hoc
will open the simulation windows.

\
Questions on the model parameters should be directed to the
authors.

Questions on how to use this model with NEURON
should be directed to [email protected]

Changelog:
----------
2024-10: Converted readme to markdown