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read-the-docs-community bot commented Oct 14, 2025

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@tristan-f-r tristan-f-r added the documentation Improvements or additions to documentation label Oct 14, 2025
For this dataset, two interactomes are merged (directed edges prioritized when available):

Databases, such as STRING, contatin interactomes that represent known interacts between proteins.
- iRefIndex v13 (159,095 undirected interactions)
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Does iRefIndex store any particular interaction like PhosphoSitePlus's kinase-substrate interactions? (We should also link to the pages.)

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I have no idea of the top of my head, but we can link the paper https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-9-405#Sec30.

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I believe iRefWeb, the website version of iRefIndex, is no longer available, so here are screenshots I have that I use to present the data it has:
image
image

Everything is a protein-protein interaction. The MI codes are an ontology describing those interactions.

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TODO: add in the errors that people could possibly run into
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[We can do this in a separate PR if we want to merge this first update in first, unless we prefer bigger documentation PR updates.]

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I think this is a work in progress for now and will constantly be updated. This could be it's own pr but if I have time I will have some stuff to add to it.

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Should this be a general troubleshooting page with a subsection on Docker?

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Oh that actually would be a better page.

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We should drop this file before merging in this PR.

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Here are two final rephrasing suggestions. Then I think we should merge and use this version for Wednesday. We can continue improving it afterward.

@ntalluri ntalluri requested a review from agitter October 21, 2025 00:35
@agitter agitter merged commit 544ca29 into Reed-CompBio:main Oct 21, 2025
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3 participants