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Releases: google-deepmind/alphagenome_research

v0.2.0

02 Apr 16:00

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Added

  • Non-zero mean computation to fine-tuning notebook.
  • Gene LFC loss for GenomeTracksHead.
  • Align alternate predictions for splice junctions when making indel
    predictions.

Changed

  • Fix splice-site and splice-site usage scoring to use the correct gene mask
    extractor.
  • Only consider splice sites that are within a gene body, and overlaps with
    the provided variant.
  • Pass requested outputs to the model prediction call, significantly reducing
    roofline memory consumption by eliding redundant computation.
  • Pad gene masks in gene scoring. This reduces the number of jit
    recompilations for different numbers of genes.

v0.1.0

20 Feb 09:46

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Added

  • Add code and notebook example for fine-tuning AlphaGenome.
  • Better support for loading pre-trained model with different heads and
    metadata.

Changed

  • Various fixes to better align predictions with the AlphaGenome API (e.g.
    metadata column names).
  • Fixed variant extraction to correctly insert variants on the negative
    strand.

v0.0.1

28 Jan 15:37

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Initial release.