Skip to content

mattspotnitz/Covid19PredictionStudies

 
 

Repository files navigation

Covid19PredictionStudies

Study Status: Started

  • Analytics use case(s): Patient-Level Prediction
  • Study type: Clinical Application
  • Tags: -
  • Study lead: Jenna Reps, Ross Williams, Peter Rijnbeek
  • Study lead forums tag: jreps, RossW, Rijnbeek
  • Study start date: Mar 26, 2020
  • Study end date: -
  • Protocol: -
  • Publications: -
  • Results explorer: -

This study repo will include all the prediction model development and validation packages from the covid-19 OHDSI study-a-thon

Background

The Corona Virus Disease 2019 (COVID-19), which started in late 2019 as an epidemic in Wuhan, Hubei Province, China, has been classified as a pandemic and a public health emergency of international concern by the World Health Organisation (WHO) in January 2020.

The OHDSI community has initiated a study-athon to attempt to provide evidence to healthcare providers, governments and patients to best aid in the understanding and treatment of the pandemic.

This specific repository contains the work of the Patient-Level Prediction group in aiding this effort.

Patient-Level Prediction Studies

There are various packages contained here:

1) Predicting which patients with signs/diagnosis will require hospitalization

The objective of this study is to inform the triage and early management of patients with diagnosed or suspected COVID-19, by developing and validating a patient-level prediction model to identify adult patients at risk of hospitalization after presenting with flu or flu-like symptoms at a general practitioner (GP), outpatient (OP) or emergency room (ER) visit.

When should this model be used? When a patient first has a diagnosis of symptom of covid-19

Protocol: link

Packages

  • OHDSI model development: link
  • OHDSI model validation: link
  • Existing model validation:

Results

Shiny app: link

2) Predicting which patients sent home after being seen at outpatient for flu or flu-like symptoms end up in hospital 2-30 days later

The objective of this study is to identify the most patients at risk of being hospitalized amongst those who have been sent home after presenting with flu and COVID-19 or symptoms.

When should this model be used? When a patient is about to be sent home after being seen with suspected covid-19

Protocol: link

Packages

  • OHDSI model development: link
  • OHDSI model validation: link
  • Existing model validation:

Results

Shiny app: link

3) Predicting which patients admitted to hospital for pneumonia will be more severe (e.g., require ventilator or ICU)

The objective of this study is to identify the most high risk patients amongst those who have been admitted to hospital with pneumonia and COVID-19.

When should this model be used? When a patient is first admitted to hospital with suspected covid-19

Protocol: link

Packages

  • OHDSI model development: link
  • OHDSI model validation: link
  • Existing model validation:

Results

Shiny app: link

4) Simple Models

This package contains the software used in the development of a simple model to answer the two prediction questions. This was done so as to increase the usability of the models in practice by reducing the feature set, whilst being provided with a benchmark to measure against.

Packages

  • OHDSI simple for Q1: Being Uploaded Soon
  • OHDSI simple for Q2:
  • OHDSI simple for Q3:

Results

Shiny app: Link

Instructions for participation

To run these studies you need the following software installed:

  • [Required] R (version 3.3.0 or higher).
  • [Required] Java (Java can be downloaded from http://www.java.com)
  • [optional] Python installation may be required for some of the machine learning algorithms. We advise to install Python 3.7 using Anaconda (https://www.continuum.io/downloads).

You need to install the latest version of the PatientLevelPrediction R package (version 3.0.15):

install.packages('devtools')
devtools::install_github('ohdsi/PatientLevelPrediction')

About

Development and validation OHDSI network studies for the covid19 prediction topic

Resources

Stars

Watchers

Forks

Releases

No releases published

Packages

 
 
 

Contributors

Languages

  • R 98.4%
  • TSQL 1.6%