Rank nearest neighbors in embedding space #211
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An ideal cell state representation has the following properties:
We observed these properties for time-regularized models visually in UMAPs. However, Euclidean distances in UMAP space carry no global meaning, so the observations cannot be directly quantified by comparing UMAP values. This PR provides methods to describe the embedding similarities close to how UMAP is computed: each sample is ranked as the$k$ -th nearest neighbor for each sample, and the displacement in this neighborhood ($k$ at $t_{i+1}$ for each $t_i$ ) can then be used to describe the fluctuation of embeddings in a way that preserves latent space topology.
Example from ALFI dataset: